Clinical trials: Osteo Arthritis
Amputation, Osteo Arthritis Knee
Femoral Cartilage Thickness In Patients With Lower Limb Amputation
The aim of the study to investigate any relation with functional parameters and femoral cartilage thickness evaluation by ultrasonography in lower extremity amputate individuals.
- Trial name
- NCT04422717
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Osteo Arthritis Knee
Analgesic Value of Adductor Canal vs Femoral Block After Total Knee Arthroplasty
An observational study of the effect of femoral nerve block in addition to an adductor canal block for pain following total knee arthroplasty.
- Trial name
- NCT03395990
- Testing
- Active comparator: chloroprocaine
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Duke University
Osteo Arthritis Knee
Knee Biofeedback Rehabilitation Interface for Game-based Home Therapy for Patients With Knee Osteoarthritis
Osteoarthritis (OA) is the leading cause of disability in the United States. As osteoarthritis is associated with the lower limb muscle weakness, rehabilitation through quadriceps strengthening is a well-established treatment for…
- Trial name
- KneeBRIGHT (NCT04187092)
- Testing
- KneeBright Group, Standard Rehabilitation group
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Virginia
Osteo Arthritis Knee
Traditional Versus Alternative Alignment in TKR
As many as 20% of patients are unhappy with the results of total knee replacement (TKR). Various changes to surgical technique have tried to address this but have not led to a significant improvement in the numbers of patients…
- Trial name
- NCT03196011
- Testing
- TKR with mechanical alignment method, TKR with alternative alignment method
- Where
- United Kingdom
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Neurogenic Myositis Ossificans, Neurogenic Para-osteo-arthritis
Comparison Between CT and MRI in Preoperative Evaluation of Neurogenic Myositis Ossificans or Neurogenic Para-osteo-arthritis
The principal objective of the study is to compare between CT and MRI diagnostic performance (sensibility and specificity) in the preoperative assessment of neurogenic para-osteo-arthritis.
- Trial name
- MON-IRM (NCT03832556)
- Testing
- CT scan, MRI examination
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis
Gait Rehabilitation to Treat FastOA
The purpose of this study is to determine the effects of real-time gait biofeedback delivered over a 6-week period on early markers of FastOA and conduct 6-week and 6-month follow-up assessments in anterior cruciate ligament…
- Conditions
- Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Knee Osteoarthritis, Osteo Arthritis Knee
- Trial name
- NCT05848622
- Testing
- Real-time gait biofeedback
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of North Carolina, Chapel Hill
Osteo Arthritis Knee, Central Sensitisation
Central Sensitization in Knee Osteoarthritis
The stimuli that activate nociceptors cause the dorsal horn of the spinal cord neurons to be sensitive to low-intensive afferent stimuli by decreasing the excitation threshold in patients with osteoarthritis.
- Trial name
- NCT04308967
- Testing
- balance exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cukurova University
Pain, Osteo Arthritis Knee
Clinical Trial to Evaluate the Efficacy and Safety of LEVI-04 in Patients With Osteoarthritis of the Knee
This is a phase 2, randomized, double-blind, placebo-controlled trial of multiple doses and multiple administrations of LEVI-04 for the treatment of pain due to osteoarthritis of the knee.
- Conditions
- Pain, Osteo Arthritis Knee, Knee Osteoarthritis, Arthritis
- Trial name
- NCT05618782
- Testing
- LEVI-04
- Where
- 13 sites in Czechia, Denmark and 3 more
- Volunteers
- 518 people
- Sponsor
- Levicept
Osteoarthritis, Knee, Osteo Arthritis Knee
Study to Evaluate Resiniferatoxin in Patients With Knee Osteoarthritis Whose Total Knee Replacement Surgery is Delayed
Efficacy and safety study of resiniferatoxin versus placebo to manage pain in patients with knee osteoarthritis whose TKR surgery is delayed
- Conditions
- Osteoarthritis, Knee, Osteo Arthritis Knee, Knee Pain Chronic
- Trial name
- NCT04386980
- Testing
- Resiniferatoxin
- Sponsor
- Sorrento Therapeutics, Inc.
Knee Osteoarthritis
Tele-rehabilitation in Knee Osteo Arthritis
Osteoarthritis (OA) is the most common degenerative joint disease with an inflammatory component that starts from the matrix of the articular cartilage.
- Trial name
- NCT06430242
- Testing
- Tele rehabilitation, Exercise
- Where
- Saudi Arabia
- Volunteers
- 56 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Knee Osteoarthritis, Knee Arthritis
ROMTECH PortableConnect Rehabilitation Device Usage Post Unilateral Total Knee Arthroplasty (TKA)
ROMTech is focused on transforming the healthcare market by delivering lower extremity rehabilitation systems that are effective, efficient for patient use, cost-effective, and provide better patient outcomes while simultaneously…
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Disease
- Trial name
- NCT04497129
- Testing
- ROMTech PortableConnect, Traditional Rehabilitation and CPM Device
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- ROM Technologies, INC
Knee Osteoarthritis, Osteo Arthritis Knee
Effectiveness of Physical Therapy in Stem Cell Transplant Recipients for Knee Osteoarthritis
Knee osteoarthritis has been considered as 11th highest contributor factor to nonfatal burdens in the world. It is considered one of the most common degenerative diseases of synovial joint and major cause of muscle impairment…
- Conditions
- Knee Osteoarthritis, Osteo Arthritis Knee, OA Knee
- Trial name
- NCT05959902
- Testing
- Forward Walking, Physiotherapy Exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 48 people
- Sponsor
- Dow University of Health Sciences
Pain, Chronic, Dementia, Mild
Developing a Nonpharmacological Pain Intervention for Community-dwelling Older Adults With Dementia
The purpose of this study is to develop an exercise treatment program for knee osteoarthritis that works well for people with memory problems. This study will include two parts.
- Conditions
- Pain, Chronic, Dementia, Mild, Mobility Limitation, Physical Disability
- Trial name
- NCT06264362
- Testing
- Tailored Physical Activity Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Drexel University
Knee Osteoarthritis
Regenerative Medicine of Articular Cartilage: Characterization and Comparison of Chondrogenic Potential and Immunomodulatory Adult Mesenchymal Stem Cells
Articular cartilage can be the seat of many diseases including osteoarthritis and traumatic defaults. The cartilage has no intrinsic ability to repair resulting at long term in function loss in the joints.
- Trial name
- ARTHROSTEM (NCT01879046)
- Testing
- arthroplasty
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Nantes University Hospital