Clinical trials: Osteo Arthritis
Orthopedic, Osteo Arthritis Knee
Energy Status and Protein Intake As Prognostic Indicators of Rehabilitative Outcomes
The proposed project is novel in its goal to establish a foundation for evidence-based rehabilitative nutrition guidelines to enhance perioperative patient care and improve post-operative rehabilitative outcomes specific to…
- Conditions
- Orthopedic, Osteo Arthritis Knee, Hip Osteoarthritis, Protein-Energy Malnutrition
- Trial name
- ESPI-PRO (NCT06734845)
- Testing
- Total Knee Arthroplasty, Total Joint Arthroplasty
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Osteo Arthritis Knee, Arthritis
Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Knee Pain Related to Osteoarthritis
The purpose of this study is to assess the ability of long-duration low-intensity therapeutic ultrasound (LITUS) to alleviate knee Osteoarthritis pain over an 8-week period.
- Trial name
- NCT05882812
- Testing
- Sustained Acoustic Device with 2.5% Diclofenac Patch, Sustained Acoustic Device with 0% Diclofenac Patch, 2.5% Diclofenac Patches
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- ZetrOZ, Inc.
Osteo Arthritis Knee, Arthritis
Sustained Acoustic Medicine (SAM) Combined With a Diclofenac Ultrasound Coupling Patch for Knee Osteoarthritis
The purpose of this study is to measure the effectiveness of Sustained Acoustic Medicine (SAM) treatment combined with diclofenac ultrasound coupling gel in patients with stage II and stage III knee osteoarthritis.
- Trial name
- SAM (NCT04391842)
- Testing
- Sustained Acoustic Device with 1% Diclofenac patch
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- ZetrOZ, Inc.
Total Shoulder Arthroplasty, Osteo Arthritis Shoulders
Posterior Approach to Total Shoulder Arthroplasty
The purpose of this study is to evaluate preoperative objective measurements and operative objective measurements to determine if there is any effect to postoperative outcomes.
- Trial name
- pTSA (NCT03623269)
- Testing
- posterior approach to total shoulder arthroplasty
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- The Orthopaedic Research & Innovation Foundation
Knee Osteoarthritis
Follow-up of Osteo-articular Biomarkers After Spa Therapy in a Population With Knee Osteoarthritis and Their Correlation With the Clinical Evolution
Spa therapy is used in the treatment of various diseases and mainly osteoarthritis. Knee osteoarthritis is a very common rheumatic disease whose prevalence increases with longer life span and is a public health problem.
- Trial name
- BIOMARTHROSE (NCT04308369)
- Testing
- Blood collection arm
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- CHI MONT DE MARSAN ET PAYS DES SOURCES
Osteo Arthritis Knee
Effects of Exercise Versus Topical Agents on Knee Osteoarthritis
Osteoarthritis, a chronic and degenerative joint disease, is the most common type of arthritis and affects more than 300 million adults worldwide.
- Trial name
- NCT05827003
- Testing
- Exercise, Exercise&Topical Agent, Topical Agent
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Osteo Arthritis Knee
Surgical Excision of the Fat Pad
Introduction: The infrapatellar fat pad (Hoffa's fat pad) is a structure which is located intra-articularly. Its function is not well known.
- Trial name
- NCT04503512
- Testing
- removal of fat pad, non removal of fat pad
- Where
- United Kingdom
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Osteo Arthritis Knee, Pain, Chronic
Study of the Effects of Photobiomodulation in Patients With Osteoarthritis
PhotoBioModulation (PBM) is a mature science with therapeutic efficacy in humans and animals, and with excellent results in different medical specialties without side effects.
- Conditions
- Osteo Arthritis Knee, Pain, Chronic, Inflammation
- Trial name
- NCT03924128
- Testing
- Photobiomodulation
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Osteo Arthritis Knee, Pain, Postoperative
Single Dose Adductor Canal Block vs SPANK Block for TKA
This is a prospective, randomized control trial to compare SPANK block combined with adductor canal block to adductor canal block alone in treatment of post-operative pain after total knee arthroplasty.
- Conditions
- Osteo Arthritis Knee, Pain, Postoperative, Pain, Acute
- Trial name
- NCT03502889
- Testing
- SPANK Block (Sensory Posterior Articular Nerves of the Knee), Adductor Canal Block, Ropivacaine Hcl 0.5% Inj Vil 30Ml
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- San Antonio Uniformed Services Health Education Consortium
Arthritis, Osteo Arthritis Knee
Osteoarthritis Care Tools for Primary Care Providers
The purpose of this pilot study is to test OACareTools+, an intervention for healthcare providers that combines education, patient resources and support from a national organization, to help them make referrals of patients with…
- Trial name
- OACareTools (NCT06988163)
- Testing
- OACareTools+
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Osteo Arthritis of the Knee, Pain
The Effectiveness of BETY in Knee Osteoarthritis With Intra-Articular Injections
Osteoarthritis (OA) is the most common condition in middle-aged and elderly populations; it causes pain and physical disability and is characterized by cartilage degeneration, changes in bone tissue, inflammation of the synovial…
- Conditions
- Osteo Arthritis of the Knee, Pain, Pain Management, Exercise
- Trial name
- NCT07496203
- Testing
- BETY
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy, Osteo Arthritis Knee
[Tc-99m]-RPI-087 as an Imaging Marker in Osteoarthritis of the Knee Compared to Healthy Volunteers
The main purpose of this study is to test the safety and tolerability of T-087. The study will enroll 6 healthy volunteers (HVs) and 6-18 subjects with KOA.
- Trial name
- NCT03503825
- Testing
- [Tc-99m]-RPI-T-087 Injection
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Reiley Pharmaceuticals Inc.
Osteo Arthritis Knee
Long-Duration Ultrasound for Knee Osteoarthritis
This study will measure the 24-week pain relief from long-duration ultrasound on the symptoms of knee arthritis pain.
- Trial name
- NCT03800927
- Testing
- Long duration ultrasound
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ZetrOZ, Inc.
Arthritis;Lumbosacral, Osteo Arthritis Knee
Cooled RF Lesion MRI Characteristics
This Prospective, Single-center, Pilot Study will assist in gaining an understanding of the actual CRFA lesions in an in vivo situation in areas where CRFA is utilized as a standard of care treatment option for the relief of…
- Conditions
- Arthritis;Lumbosacral, Osteo Arthritis Knee, Sacroiliitis, Hip Osteoarthritis
- Trial name
- NCT03631030
- Testing
- Cooled radiofrequency ablation
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- International Spine, Pain and Performance Center
Steatohepatitis, Nonalcoholic, Osteo Arthritis
DDI Study of ECC0509 With Metformin, Midazolam, and Caffeine
This is a Phase 1, open-label, 2-part, fixed-sequence, single-center, two-period, drug-drug interaction trial in healthy adult participants to determine if ECC0509 administration at steady state affects the pharmacokinetics (PK)…
- Trial name
- NCT07873229
- Testing
- ECC0509, Metformin, Caffeine
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Eccogene
Osteo Arthritis Knee
The Use of Bone Growth Stimulators for Osteoarthritis of the Knee.
The hypothesis of this study is that since osteoarthritis of the knee is primarily a bone disease where the joint changes are secondary, and bone growth stimulators function to decrease intraosseous venous congestion and remodel…
- Trial name
- NCT03476382
- Testing
- Ultrasound Bone Growth Stimulator
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Coastal Carolinas Integrated Medicine
Osteo Arthritis Shoulders, Avascular Necrosis of the Head of Humerus
Easytech Reversed Shoulder System Clinical Study
The purpose of the study is to collect data to demonstrate the safety and effectiveness of the Easytech Reversed Shoulder System for the treatment of patients who require a reverse total shoulder arthroplasty.
- Conditions
- Osteo Arthritis Shoulders, Avascular Necrosis of the Head of Humerus, Rotator Cuff Tear
- Trial name
- NCT03806842
- Testing
- Easytech group
- Where
- 6 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- FX Shoulder Solutions
Osteo Arthritis Knee
Efficacy of Ipack Block and Surgeon's Joint Infiltration in Total Knee Arthroplasty
Total knee arthroplasty(TKA) is an effective modality for the treatment of advanced osteoarthritis of the knee joint with excellent outcomes.
- Trial name
- NCT03653416
- Testing
- Ipack, Bupivacaine, Peri Articular Infiltration
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Osteo-arthritis
Oral Supplement in Older Adults to Support Physical Fitness and Mental Well-being
Cucumbers have been anecdotally claimed to have anti-inflammatory activity for a long time, but the active principle was not identified.
- Trial name
- PQQA (NCT05878847)
- Testing
- Q-actin
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aberystwyth University
Shoulder Pain, Rotator Cuff Tears
Finnish Imaging of Shoulder Study
In the Finnish Imaging of Shoulder study we will recruit 600 participants from a nationally representative general population sample.
- Conditions
- Shoulder Pain, Rotator Cuff Tears, Glenoid Labrum Tear, Osteo Arthritis Shoulders
- Trial name
- FIMAGE (NCT05641415)
- Testing
- Imaging
- Where
- Finland
- Volunteers
- 603 people, healthy volunteers welcome
- Sponsor
- University of Helsinki