Clinical trials: Orthostatic Hypotension
Spinal Cord Injuries, Orthostatic Hypotension
Speed of Robotic Leg Movements and Orthostatic Hypotension in Subacute SCI
This study seeks to evaluate whether the speed (cadence) of lower extremity robotic movement has an impact on orthostatic hypotension and upright tolerance when training with the ErigoPro robotic tilt-stepper.
- Trial name
- NCT04029974
- Testing
- ErigoPro
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Methodist Rehabilitation Center
Hypertension
Impact of Citrulline and Arginine Supplementation on the Post-exercise Hypotension (PEH)
Post-exercise hypotension (PEH) is a established phenomenon as one of the non-pharmacological ways of reducing blood pressure, producing important impacts, particularly in hypertensive individuals.
- Trial name
- PEH (NCT03378596)
- Testing
- L-citrulline + L-arginine, L-arginine, L-citrulline
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Juliano Casonatto
Orthostatic Hypotension, Ischemia
Evaluation of the ORTHO-LBNP System
The pilot study aims to evaluate a prototype system that enables military pilots to train under conditions of orthostatic hypotension and ischemic hypoxia.
- Conditions
- Orthostatic Hypotension, Ischemia, Hypoxia
- Trial name
- ORTHO-LBNP (NCT03354234)
- Testing
- Head up tilt (HUT), Lower body negative pressure (LBNP), Head down tilt (HDT)
- Where
- Poland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Military Institute of Aviation Medicine
Orthostatic Hypotension, Syncope
The Effect of Water Carbonation on Orthostatic Tolerance
The primary purpose of this investigation is to determine whether water carbonation can improve orthostatic tolerance in healthy control volunteers.
- Conditions
- Orthostatic Hypotension, Syncope, Vasovagal Syncope
- Trial name
- NCT05621460
- Testing
- 500mL carbonated water, 500mL still water, 50mL still water
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Orthostatic Hypotension, Sarcopenia
Sarcopenia and Orthostatic Hypotension
Elderly patients generally have a tendency for having sarcopenia which refers to muscle loss that may be related to many factors. These patients also have a tendency to falls and injuries.
- Trial name
- NCT03732716
- Testing
- blood pressure measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Postexercise Hypotension
Continuous vs Aerobic Postexercise Hypotension
This study examines the effect of obesity and gender on postexercise hypotension with three different randomized exercise protocols or varying intensity.
- Trial name
- CAPER (NCT03313375)
- Testing
- Continuous Exercise, Aerobic Interval Exercise
- Where
- 2 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Orthostatic Hypotension
Dawn Simulation and Postural Hypotension
One of the most physiologically demanding things that older people do every day is to get up in the morning. After spending a night laying flat, where the blood distributes evenly across the body, when they stand in the morning…
- Trial name
- NCT02632318
- Testing
- Light
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Hypotension, Orthostatic Hypotension
Orthostatic Hypotension Among Veterans
Orthostatic hypotension (OH) is defined as a fall in blood pressure when standing. Several different underlying diseases, conditions, or combinations of medicines may contribute to OH; therefore the cause of the condition varies…
- Trial name
- OH (NCT02123303)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Hypertension, Autonomic Dysfunction
Autonomic Regulation of Blood Pressure and Heart Rate During Orthostasis and Exercise in Healthy and Hypertensive Individuals
The goal of this observational study is to assess arterial stiffness and autonomic regulation of blood pressure and heart rate in healthy adults and people with arterial hypertension during orthostatic stress and graded physical…
- Conditions
- Hypertension, Autonomic Dysfunction, Orthostatic Hypotension
- Trial name
- NCT07482462
- Where
- Slovenia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Post-Exercise Hypotension
Resistance Exercise Modify Cardiovascular Responses of Professors During Teaching and Sleep
Both work activity and reduced nocturnal dipping of blood pressure are related to increased cardiovascular risk. The aim of the present study was to assess the hemodynamic and autonomic responses of university professors during…
- Trial name
- NCT02650089
- Testing
- Resistance Exercise Low intensity, Resistance Exercise High intensity, Control
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do vale do São Francisco
Glucose Response, Blood Pressure
Effects of Meal and Exercise Sequence on Glucose and Blood Pressure Responses
The purpose of this study is to investigate whether the sequence meal and exercise (exercise before meal or exercise after meal) affects the postprandial metabolism.
- Trial name
- NCT06949683
- Testing
- Meal-Exercise, Exercise-Meal
- Where
- Taiwan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Hypotension, Orthostatic
Posture Detection for Automated Abdominal Binder
The automated inflatable abdominal binder is an investigational device for the treatment of orthostatic hypotension (low blood pressure on standing) in autonomic failure patients.
- Trial name
- NCT02280369
- Testing
- Automated abdominal binder
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Blood Pressure, Post-Exercise Hypotension
The Effects of Dietary Salt on Post-exercise Hypotension
The new American Heart Association (AHA) blood pressure guidelines are expected to raise the prevalence of high blood pressure to ~46% in the United States.
- Trial name
- NCT03565653
- Testing
- High dietary salt
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Healthy Women Volunteers
A Single Pole Dancing Session and Its Effects on Blood Pressure
This study aimed to evaluate the acute blood pressure (BP) response after a single pole dance (PD) session in adult women. Twenty-one young women (<31 years old) with normal BP and previous PD experience participated.
- Trial name
- NCT07590258
- Testing
- Pole Dance
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Catarina
Orthostatic Hypotension
Vitamin K Status and Markers of Vascular Function in Patients With and Without Postural Hypotension
Postural hypotension is common in older people, leading to falls, decline in function, and dependence. Available treatments have limited efficacy and tolerability; novel approaches to treatment are therefore needed.
- Trial name
- VITKOH (NCT02505282)
- Testing
- Vitamin K status
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Dundee
Hypertension
Post-Exercise Hypotension in Elderly Hypertensive Men
The purpose of this study is to compare the effects of two exercise protocols on post-exercise blood pressure versus a control group in elderly hypertensive men.
- Trial name
- HPE (NCT02415582)
- Testing
- Aerobic exercise, Combined exercises, Control
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hypertension, Elevated Blood Pressure
Blood Pressure Following Isometric Exercise in Inactive Adults
This study investigates how isometric exercise training (IET) affects blood pressure in physically inactive adults. Isometric exercise involves sustained muscle contractions without movement-for example, pushing against a fixed…
- Conditions
- Hypertension, Elevated Blood Pressure, Sedentary Lifestlye
- Trial name
- BELIEF-BP (NCT06937164)
- Testing
- Isometric Exercise Training (IET), Expectation-Enhancing Informational Framing
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Canterbury Christ Church University
Post-Exercise Hypotension, Ambulatory Blood Pressure Monitoring
Exercise Timing on the Morning Blood Pressure Surge
The goal of this clinical trial was to assess the effects of morning vs. evening high-intensity interval exercise on the magnitude of the morning blood pressure surge in young healthy adults.
- Conditions
- Post-Exercise Hypotension, Ambulatory Blood Pressure Monitoring, High-intensity Interval Exercise
- Trial name
- NCT06702930
- Testing
- Morning high-intensity interval exercise, Evening high-intensity interval exercise
- Where
- Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Hypotension, Orthostatic, Hypertension
Effects of Melatonin to Reduce Nocturnal Hypertension in Patients With Neurogenic Orthostatic Hypotension
Neurogenic Orthostatic Hypotension (NOH) is clinically defined as a consistent drop in systolic blood pressure (SBP) ≥30mmHg upon standing from a seated or lying position.
- Conditions
- Hypotension, Orthostatic, Hypertension, Autonomic Nervous System Diseases
- Trial name
- NCT02963181
- Testing
- Yohimbine, Melatonin
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Orthostatic; Hypotension, Neurogenic
Treatment and Prognosis of Neurogenic Orthostatic Hypotension : A Prospective Randomized Study
Compare the effect of treatment of midodrine and pyridostigmine in neurogenic orthostatic hypotension and investigate the quality of life of treatment of neurogenic orthostatic hypotension.
- Trial name
- NCT02308124
- Testing
- Midodrine, Pyridostigmine Bromide, Midodrine + pyridostigmine
- Where
- South Korea
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital