Clinical trials: Orthopedic
Arthropathy of Knee, Arthropathy of Hip
Nirvana Super Pro Supplementation in Orthopedic Surgery Patients
The purpose of this study is to investigate orthopedic patients undergoing either a total hip replacement (THR) or total knee arthroplasty (TKR) using two dietary supplements, PREPARE and RECOVER, and their recovery times…
- Trial name
- NCT06203691
- Testing
- Supplementation with Nirvana Super Pro Liquid Supplements, Non-Supplementation Group
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nirvana Water Sciences Corp
Dexamethasone, Bupivacaine
Effect of Adding Dexamethasone to Bupivacaine in Ultrasound-Guided Supraclavicular Brachial Plexus Blocks Versus Bupivacaine Alone for Upper Limb Orthopaedic Surgery
SCBPBs provides optimal conditions for procedures performed below the mid-upper arm (elbow, forearm, wrist, hand) due to its high success rate and ease of access.
- Conditions
- Dexamethasone, Bupivacaine, Upper Limb Surgery
- Trial name
- SCBPBs (NCT07399691)
- Testing
- Dexamethasone 8 mg
- Where
- Ethiopia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Arsi University
Spinal Anesthetic Toxicity, Inferior Vena Cava Abnormality
Transthoracic Echocardiography of Inferior Vena Cava Before Spinal Anesthesia Can Predict Hypotension
Study Protocol: Outcome Measurements Primary Outcome The main outcome will be the preoperative performance of the dIVCmax/IVCCI ratio to foresee the incidence of hypotension after spinal anesthesia in a greater extent to that of…
- Conditions
- Spinal Anesthetic Toxicity, Inferior Vena Cava Abnormality, Intraoperative Complications
- Trial name
- NCT03266250
- Testing
- spinal anesthesia
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Staphylococcus Aureus, Surgical Wound Infection
Risk Factors for Staphylococcus Aureus Surgical Site Infections in Orthopedic and Trauma Surgery
The most commonly identified organism for Surgical Site Infection (SSI) in orthopedic surgery is Staphylococcus aureus but risk factors for mono microbial S.aureus SSI are not well-known.
- Conditions
- Staphylococcus Aureus, Surgical Wound Infection, Orthopedic Disorder, Traumatology
- Trial name
- ISO (NCT03040960)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Grenoble
Radiation Exposure
A Prospective Study of Radiation Exposure to Surgeons
The purpose of this study is to measure the amount of radiation over a specific period of time that Orthopaedic Surgeons are exposed to while using the mini c-arm fluoroscopy machine.
- Trial name
- NCT00378053
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Bone Metastases, Lower Extremity Fracture
External Beam Radiation Therapy Post Surgery in Patients With Lower Extremity Bone Metastases Randomized Efficacy Trial
The objective of the present study is to evaluate the effectiveness of post-operative radiation therapy in lower extremity bone metastases.
- Conditions
- Bone Metastases, Lower Extremity Fracture, Pathological Fracture, Impending Fracture
- Trial name
- EXPLORE (NCT04109937)
- Testing
- External beam radiation therapy
- Where
- Canada
- Sponsor
- Sunnybrook Health Sciences Centre
Orthopedic Procedures, Tranexamic Acid
Thromboelastogram During Total Knee Replacement
Verify the changes in coagulation system during total knee replacement surgery with tranexamic acid single bolus infusion.
- Trial name
- NCT02373969
- Volunteers
- 30 people
- Sponsor
- Rambam Health Care Campus
Orthopedic Disorder
Digital Preop-planning of Total Hip Arthroplasties
Residual leg length discrepancy is a common issue after total hip arthroplasty(THA). Digital preoperative planning may improve the accuracy of the surgical procedure and may help the surgeon to precisely predict implants sizes
- Trial name
- PLANORTHO (NCT04090372)
- Testing
- evaluation of pre-op planning using Traumacad
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Toulouse
Musculoskeletal Diseases
Sacroiliac Orthopedic Blocking and Cervical Spine Function
This study seeks to determine if the correction of a sacroiliac lesion can produce a functional change in cervical spine. Reduction of a sacroiliac joint lesion may alter cervical spine function.
- Trial name
- NCT00523822
- Testing
- Spinal Manipulative Therapy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Logan College of Chiropractic
Pulmonary Embolism, Deep Vein Thrombosis
Study to Develop a Reliable Nomogram That Incorporates Clinical and Genetic Information
In this research study, the investigators are trying to find a better way to set the dose of a common blood-thinning medication.
- Conditions
- Pulmonary Embolism, Deep Vein Thrombosis, Atrial Fibrillation
- Trial name
- NCT00401414
- Testing
- Warfarin
- Where
- 2 sites in United States
- Volunteers
- 344 people
- Sponsor
- Brigham and Women's Hospital
Orthopaedic Related Pain (Musculoskeletal Pain)
Pain in America: A Randomized Controlled Trial
Each day orthopaedic surgeons worldwide treat patients with musculoskeletal pain. But little evidence exists about orthopaedic patient understanding of the common methods of managing musculoskeletal pain.
- Trial name
- NCT02710695
- Testing
- Control, Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Missouri, Kansas City
Proximal Femoral Fracture
Proximal Femur Image Database Validation
The AO@AI Turin project is a collaborative project with a Turin group and the AO (Arbeitsgemeinschaft für Osteosynthesefragen, or in English, Association for the Study of Internal Fixation) foundation.
- Trial name
- NCT06351943
- Testing
- Fracture classification annotations provided by the Turin group, Fracture classification annotations provided by the AO expert surgeon group
- Where
- Switzerland
- Volunteers
- 2,932 people
- Sponsor
- AO Innovation Translation Center
Lower Limb Orthopedic Surgery
Intravenous Dexmedetomidine Versus Midazolam in Preventing Shivering in Trauma Patients Undergoing Lower Limb Orthopedic Surgery Under Spinal Anesthesia
Shivering is a common and significant complication following spinal anesthesia, with a reported incidence of 40-60% especially in trauma patients due to pain, stress response, blood loss, and disrupted thermoregulation.
- Trial name
- NCT07300826
- Testing
- Dexmedetomidine, Midazolam
- Volunteers
- 100 people
- Sponsor
- Assiut University
ClassII Division 1 Malocclusion, Mandibular Retrognathism
Effects of Orthopedic Mandibular Advancement in Class II Division 1 Malocclusion on Pharyngeal Airway
This study aims at evaluating the effects of mandibular advancement on pharyngeal airway space and nocturnal breathing in children with skeletal class II division1 malocclusion.
- Trial name
- NCT04255511
- Testing
- Twin Block, Fixed orthodontic appliance
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Venous Thromboembolism, Deep Vein Thrombosis
Weight-Based Enoxaparin Dosing and Real-Time Dose Adjustment in Orthopaedic Trauma
The rates of Venous thromboembolism (VTE) after orthopedic surgery are as high as 40-60% without prophylactic measures. Enoxaparin, a low-molecular-weight heparin, produces an anticoagulant effect by binding antithrombin, thereby…
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolus
- Trial name
- NCT03339349
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Utah
Orthopedic Surgery of Lower Extremity
Evaluation of Continuous Saphenous Nerve Block to Supplement a Continuous Sciatic Nerve Block After Ankle Surgery
A nerve block catheter is a small tube placed next to a nerve through a needle, and the needle is then removed. Numbing medicine is dripped through the tube to reduce pain sensation from the nerve.
- Trial name
- NCT01167907
- Testing
- 0.2% ropivacaine, saline
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Wake Forest University Health Sciences
Cleft Lip and Palate
Two Methods of Lip Taping as a Presurgical Orthopedic Appliance
A randomized clinical trial to compare the effectiveness of two methods of lip taping as a presurgical orthopedic appliances on maxillary arch dimensions in infants with bilateral cleft lip and palate.
- Trial name
- NCT05796336
- Testing
- Lip taping
- Where
- Iraq
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Acromioclavicular Joint Dislocation
Reconstruction Of Acute Coracoclavicular Ligament Disruption With and Without Tendon Graft
To evaluate patient function, radiographic changes and complication rates of acute coracoclavicular (CC) joint reconstruction with and without the use of tendon graft as an augmentation to repair.
- Trial name
- NCT03060564
- Testing
- tendon graft, No intervention
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Dr. Brian Lee
Teach-Back Communication, Arthritis
Analyzing Challenging Clinical Discussions in Orthopaedics
The goal of this study is to analyze patient:provider communication surrounding the discussion of difficult clinical conversations such as knee replacement options.
- Conditions
- Teach-Back Communication, Arthritis, Knee Osteoarthritis, Knee Arthropathy
- Trial name
- NCT03058393
- Testing
- Teach-Back Lesson
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Duke University
Neurological Disorder
Side Pole Static Ankle Foot Orthosis in Children With Neurological Disorders
Transverse-plane foot deformities are a frequently encountered issue in children with neurological disorders. They are the source of many symptoms, such as pain and walking difficulties, making their prevention very important.
- Trial name
- SPS-AFO (NCT03146598)
- Testing
- No intervention as it is a observational study
- Volunteers
- 100 people
- Sponsor
- BERTHILLIER Julien