Clinical trials: Orthopaedic Surgery
Wound of Knee, Wound of Hip
Study to Compare Negative Pressure Wound Therapy or Standard Dressings After Orthopedic Surgery
The aim of this study is to assess the prevention of incision healing complications in patients undergoing Total Knee Arthroscopy (TKA) and Total Hip Arthroscopy (THA) treated with either Single-Use Incisional NPWT (Negative…
- Trial name
- PICO (NCT02064270)
- Testing
- Single-Use Negative Pressure Wound Therapy, Standard postsurgical dressings
- Where
- United States
- Volunteers
- 526 people
- Sponsor
- University of Missouri-Columbia
Arthroplasty, Replacement, Knee
Silkeborg Knee Replacement Cohort Study
In this cohort study, we will investigate short and long term outcomes after knee replacement surgery and identify preoperative and early postoperative factors associated with long term outcome.
- Trial name
- NCT03411083
- Testing
- Total or unicompartmental knee replacement
- Where
- Denmark
- Volunteers
- 1,225 people
- Sponsor
- Central Jutland Regional Hospital
Orthopedic Devices Associated With Misadventures, Infection, Surgical Site
Short Against Long Antibiotic Therapy for Infected Orthopedic Sites
The investigators will perform two concomitant RCTs, depending on the presence of infected osteosynthesis material at enrolment: SALATIO 1. Infected implant not removed (or new material inserted): Randomization 6 vs.
- Conditions
- Orthopedic Devices Associated With Misadventures, Infection, Surgical Site, Antibiotic Side Effect
- Trial name
- SALATIO (NCT05499481)
- Testing
- Antibiotic
- Where
- Switzerland
- Volunteers
- 495 people
- Sponsor
- Balgrist University Hospital
Orthopaedic Decision Making
Surgeon-Patient Communication: A Randomized Controlled Trial Evaluating the Impact of an Orthopaedic Related Smoking Cessation Discussion After Fracture Surgery
In this study, the investigators are interested in evaluating the impact of an orthopaedic related smoking cessation discussion after fracture surgery.
- Trial name
- NCT02440529
- Testing
- Intervention, Verbal Group
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Missouri, Kansas City
Knee Injuries and Disorders, Hip Injuries and Disorders
Impact of Different Educational Approaches on Post-operative Opiate Utilization After Elective Lower Extremity Surgery
The purpose of this study is to evaluate the use of post-operative opioid use after two different educational interventions. The investigators will compare changes in pain, disability and sleep between groups 6 months after…
- Conditions
- Knee Injuries and Disorders, Hip Injuries and Disorders, Opiate Addiction
- Trial name
- OpiateLEO (NCT02997644)
- Testing
- Video Education, Usual Care Group
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brooke Army Medical Center
Orthopedic Disorder
Opioid Counseling Following Orthopaedic Surgery
Postoperative pain management and opioid consumption following outpatient orthopaedic surgery may be influenced by a number of variables including knowledge of safe opioid use.
- Trial name
- NCT04138264
- Testing
- Preoperative opioid counseling
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- Rothman Institute Orthopaedics
Rehabilitation, Cerebral Palsy (CP)
Effects of Motor Imagery Training After Muscle Lengthening Surgery in Children With Cerebral Palsy
In children with cerebral palsy (CP), spasticity occurs in the muscles due to upper motor neuron lesions. The muscle groups that are mostly spastic in the lower extremity are; the hip adductor and flexors, hamstrings, and ankle…
- Conditions
- Rehabilitation, Cerebral Palsy (CP), Exercise, Tenotomy
- Trial name
- NCT06838858
- Testing
- Motor Imagery Training, Conventional Post-operative Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Saglik Bilimleri Universitesi
Surgery, Anxiety
Pediatric Preoperative Virtual Reality Program
Does the introduction of a preparatory virtual reality (VR) program that is used in the home environment, have an effect on the anxiety level of children immediately before surgery, prior to administration of preoperative…
- Trial name
- PPVRP (NCT03957525)
- Testing
- Pre-Operative Preparatory Virtual Reality Program
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- Thoralf Liebs
Idiopathic Toe-walking
Efficacy of Surgery for Idiopathic Toe Walking
BACKGROUND: For children who walk on their tip toes, surgery is often done to lengthen their Achilles Tendon. However, there is little research to help children's surgeons choose which children with idiopathic toe walking should…
- Trial name
- FOREFOOT (NCT06610591)
- Testing
- Achilles Lengthening Surgery
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Oxford
Severe Hyperglycemia, Postoperative Infection
Intraoperative Hyperglycemia and Infections After Orthopedic Surgery
Postoperative infections are a common complication. A relationship between perioperative severe hyperglycemia and postoperative infections has been found in patients undergoing craniotomy.
- Conditions
- Severe Hyperglycemia, Postoperative Infection, Orthopedic Patients
- Trial name
- NCT03903354
- Testing
- Incidence of infections within 7 days postoperatively
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Federico Bilotta
Orthopedic Disorder
End Button Tenodesis in Failed Developmental Dysplasia of the Hip Surgery
Adequate growth and development of the hip depends on two main factors: concentric positioning of femoral head into the acetabular cavity and adequate balance in growth between tri-radiate and acetabular cartilage.
- Trial name
- NCT05603858
- Testing
- Tenodesis by end button
- Volunteers
- 3 people
- Sponsor
- Al-Azhar University
Older Patients, Orthopedic Surgery
Buccal Acupuncture for Delirium Treatment in Older Patients Recovering From Orthopedic Surgery
This study is designed to test the hypothesis that, for older orthopedic patients who developed postoperative delirium, combining buccal acupuncture with routine care will shorten delirium duration and relieve delirium severity.
- Conditions
- Older Patients, Orthopedic Surgery, Postoperative Delirium, Acupuncture
- Trial name
- NCT05537155
- Testing
- Buccal acupuncture in addition to routine care, Routine care
- Sponsor
- Peking University First Hospital
Orthopedic Surgery
Monitoring of Intensity of Stimulation and Injection Pressure in US Guided Peripheral Nerve Block According to Anatomic Needle Type Position
The purpose of the study is define the minimal intensity of stimulation range at which the needle is closed to the nerve without penetrating its surface (epineurium layer) in ultrasound guided peripheral nerve blockade
- Trial name
- NCT03430453
- Testing
- Measure of the minimal intensity of stimulation during ultrasound guided peripheral nerve blockade
- Where
- 9 sites in France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Montpellier
Orthopedic Disorder
Patient-controlled Sedation With Propofol Versus Anesthesiologist-administered Sedation for Orthopedic Surgery
The purpose of this study is to compare patient satisfaction with patient-controlled sedation with propofol and anesthesiologist-controlled sedation during orthopedic procedures of the upper limb under locoregional anesthesia.
- Trial name
- PACOSA (NCT06451380)
- Testing
- orthopaedic surgery, propofol anesthesia
- Where
- France
- Volunteers
- 70 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Geriatric Population, Spinal Anesthesia Induced Hypotension
HEIGHT-BASED AND CONVENTIONAL SPINAL ANAESTHETIC DOSING IN GERIATRIC PATIENTS
The goal of this clinical trial is to find out whether height-based dosing of spinal anaesthesia provides better hemodynamic stability and anesthetic outcome than conventional fixed dosing in elderly patients undergoing lower…
- Conditions
- Geriatric Population, Spinal Anesthesia Induced Hypotension, Spinal Anesthesia in Elderly Patients
- Trial name
- NCT07363941
- Testing
- Group A : Spinal Anaesthetic Dose, Group B : Conventional Dose
- Where
- Pakistan
- Volunteers
- 104 people
- Sponsor
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma
Obstructive Sleep Apnea
Pre and Post Orthopedic Surgery Sleep and Cardiac Testing (PROSPECT)
Evaluate sleep disordered breathing before and after orthopedic surgery utilizing a FDA cleared to market (510k) home sleep study device (Nexan Inc., ClearPath System) Compare Berlin Questionnaire and Epworth Sleep Scale…
- Trial name
- PROSPECT (NCT00785070)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Memorial Health System
Hemophilia A
Phase 3/4 Study of a Recombinant Protein-Free Factor VIII (rAHF-PFM): Comparison of Continuous Infusion Versus Intermittent Bolus Infusion in Hemophilia A Subjects Undergoing Major Orthopedic Surgery
The purpose of this study is to compare the hemostatic efficacy and safety of continuous infusion versus intermittent bolus infusion in the peri- and post-operative setting, employing rAHF-PFM, a recombinant antihemophilic factor…
- Trial name
- NCT00357656
- Testing
- Recombinant Protein-Free Factor VIII (rAHF-PFM)
- Where
- 36 sites in United States, Austria and 12 more
- Volunteers
- 85 people
- Sponsor
- Baxalta now part of Shire
Lower Extremity Problem, Delirium
Intraoperative Sedatives and Postoperative Deilirium
Delirium occurs commonly in elderly patients. Its incidence after orthopedic surgery has been reported to be 5-61%. Delirium is classified into three sub-types: Hypoactive, hyperactive, and mixed.
- Conditions
- Lower Extremity Problem, Delirium, Propofol, Dexmedetomidine
- Trial name
- NCT03251651
- Testing
- Propofol, Dexmedetomidine
- Where
- South Korea
- Volunteers
- 748 people
- Sponsor
- Seoul National University Bundang Hospital
Arthroscopic Surgery, Nutrition
The Effect of Nutritional Education on Post-Arthroscopic Nutritional Status
The purpose of this study is to determine how patient nutrition effects post-operative outcomes for patients undergoing arthroscopic surgery
- Conditions
- Arthroscopic Surgery, Nutrition, Orthopedic Surgery, Shoulder Arthroscopic Surgery
- Trial name
- NCT07723742
- Testing
- Standard of Care, Nutritional Video
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Alabama at Birmingham
Orthopedic Disorder, Post Operative Pain
Nonpharmacological Management of Postoperative Pain in Children
The 3 non-pharmacological methods of online gaming, cold application, and placebo were chosen to reduce postoperative pain in children undergoing orthopedic and traumatology surgery.
- Trial name
- NCT05893680
- Testing
- Group to play online games, Group that received cold application, Group that played an online game and received cold application at the same time
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- İlke Karabıyık