Clinical trials: Orthodontic
Gingivitis, Maxillary Transversal Deficiency
St. John's Wort Oil Versus Chlorhexidine Mouthwash for Gingival Problems After Rapid Maxillary Expansion
The goal of this clinical trial was to learn whether St. John's wort (Hypericum perforatum) oil helps gum healing in children and adolescents aged 11 to 16 years after treatment with a rapid maxillary expansion appliance.
- Trial name
- SJW-CHX-RME (NCT07882771)
- Testing
- St. John's Wort Oil, Chlorhexidine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Malocclusion
A Randomised Clinical Trial: Conventional Ligation vs Figure of 8
Fixed braces (appliances) are used to straighten the malalignment of teeth. There has been a lot of research into the factors that can affect the speed of alignment of teeth but there has been very little research on how…
- Trial name
- NCT01771692
- Testing
- Extraction, Non extraction
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rachel Little
Malocclusion, Angle Class II, Overbite (Excessive) Horizontal
Long-term Stability of Treatment With the Twin Block Appliance
The objective of this observational study is to investigate the long-term stability of treatment with the Twin block appliance in a patient group previously treated with a Twin block appliance.
- Conditions
- Malocclusion, Angle Class II, Overbite (Excessive) Horizontal, Overbite (Excessive) Deep, Treatment Outcome
- Trial name
- NCT07752498
- Where
- Sweden
- Volunteers
- 72 people
- Sponsor
- Region Jönköping County
White Spot Lesion of Tooth
Fluoride Varnish, Ozone, Octenidin and WSLs in Orthodontic Patients
Objectives: to assess the efficiency of four prophylactic protocols on white spot lesions during orthodontic treatment: 1. professional mechanical tooth cleaning (PMTC)+fluoride varnish, 2.
- Trial name
- NCT04992481
- Testing
- PMTC, fluoride varnish, gaseous ozone therapy
- Volunteers
- 150 people
- Sponsor
- Pomeranian Medical University Szczecin
Malocclusion, Angle Class II
Comparison of Efficacy of Three Orthodontic Appliances
To investigate each treatment modality in its "optimal" environment to avoid operator experience bias. Therefore we propose to operate out of three "specialist centres" with specific units providing one modality alone Which of…
- Trial name
- NCT03450551
- Testing
- Twin Block, Herbst, Frog distalising appliance
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
External Apical Root Resorption in Maxillary Canines During Orthodontic Retraction
Comparison of Root Resorption in Modified Corticotomy-Assisted and Conventional Canine Retraction
This randomized controlled clinical trial will compare external apical root resorption in patients undergoing maxillary canine retraction using modified corticotomy-assisted frictionless T-loop mechanics versus conventional…
- Trial name
- MCA-CR (NCT07458139)
- Testing
- Modified Corticotomy assisted frictionless canine retraction, Conventional Frictionless Canine retraction
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Islamabad Medical and Dental College
Orthodontic Tooth Movement, Tooth Alignment
Effect of 3 Week vs 6 Week Orthodontic Appointment Intervals on Teeth Alignment
Effect of 3 week vs 6 week orthodontic appointment intervals on teeth alignment in patients with moderate to severe dental crowding: a randomized clinical trial.
- Trial name
- NCT06032702
- Testing
- tooth alignment
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Bkahtawar Amin Medical and Dental College Multan
Focus of the Study is Plaque and Gingival Index Score Before and After Instructions, Satisfaction Assessment of Orthodontic Patients With Both Instruction Modalities
Comparison of Traditional Instructions Vs AI Based Instructions With Customized Chat GPT as Remote Support System on Education of Orthodontic Patients
This study will assess the impact of voice instructions delivered by advance voice feature of Chat gpt followed by remote support with chatbot in form of customized chat gpt named Brace AI which is customized by principal…
- Conditions
- Focus of the Study is Plaque and Gingival Index Score Before and After Instructions, Satisfaction Assessment of Orthodontic Patients With Both Instruction Modalities, Knowledge Assessment, Recall Ability of Orthodontic Instructions With Both Modalities
- Trial name
- NCT07183111
- Testing
- Instructions given via artificial intelligence chatbot in form of voice instructions at chair side with Customized chatbot for remote home support, Control group instructions given by chair side orthodontist verbally and written pamphlet as home care support
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Orthodontic Brackets, Pain
Erbium-doped Yttrium Aluminum Garnet (Er:YAG) Laser vs Conventional Ceramic Bracket Debonding: A Split-Mouth Clinical Trial
This randomized split-mouth clinical trial evaluates enamel surface preservation, pulpal temperature variation, and patient-reported discomfort during ceramic orthodontic bracket removal using two Erbium-doped yttrium aluminum…
- Conditions
- Orthodontic Brackets, Pain, Temperature Change, Laser
- Trial name
- NCT07517601
- Testing
- Er:YAG Laser - Parameter 1, Er:YAG Laser - Parameter 2, Conventional Mechanical Debonding
- Where
- Lebanon
- Volunteers
- 10 people
- Sponsor
- Saint-Joseph University
Orthodontic Appliances, Adverse Effects,Gingivitis, Dental Plaque, Periodontal Diseases
Digital Manufacturing and Periodontal Performance of CAD/CAM-Customized Orthodontic Molar Bands Compared With Standard Stainless-Steel Bands
his prospective randomized clinical trial aimed to compare periodontal outcomes associated with CAD/CAM-customized orthodontic molar bands and conventional preformed stainless-steel molar bands in adolescents undergoing fixed…
- Trial name
- NCT07526805
- Testing
- Stainless-Steel Orthodontic Molar Bands
- Where
- Romania
- Volunteers
- 180 people
- Sponsor
- Dimitrie Cantemir University
Rate of Canine Retraction, Root Resorption
The Effect of Injectable PRF Vs LLL on Orthodontic Tooth Movement
The purpose of the present study is to compare the effect of injectable platelet fibrin and Low Level LASER therapy on the rate of upper canine retraction, and on root resorption of the canine
- Trial name
- NCT06520761
- Testing
- Injectable platelet rich fibrin, Low Level LASER
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Toothbrushing, Gingivitis
Effectiveness of Dual Light Electric Toothbrush vs. Manual Toothbrush in Orthodontic Patients Undergoing Oral Surgery
The study is a randomized clinical trial to compare the effectiveness of a dual light ultrasonic toothbrush on periodontal health in orthodontic patients undergoing surgery.
- Conditions
- Toothbrushing, Gingivitis, Cleft Lip and Palate
- Trial name
- NCT06122805
- Testing
- Toothbrush
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Orthodontic Treatment, Bracket Failure
Comparison of One-Step and Two-Step Light Curing of Bonding Agents and Composite in Orthodontics
Effectiveness of One-Step Versus Two-Step Light Curing of Bonding Agent and Composite in Orthodontic Bracket Bonding: Study Design: A Randomized Controlled Trial (RCT) Study Type: Interventional Allocation: Randomized…
- Trial name
- 1STEP-2STEP-LC (NCT07491796)
- Testing
- One step light curing of bonding agent and composite, Two step light curing of bonding agent and composite
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Relapse of the Lower Anterior Teeth
Comparison Between Effectiveness of Different Esthetic Orthodontic Appliances
The purpose of this study is to compare the effectiveness of active fixed lingual wire, removable aligners, and lingual braces in managing crowding of the lower anterior teeth resulting from relapse.
- Trial name
- NCT06803433
- Testing
- Aligners, Lingual braces, Active fixed lingual wire
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Intrabony Periodontal Defect
Comparison of the GTR Procedure Alone and in Combination With Immediate OTM
The aim is to evaluate in a prospective, randomized, controlled clinical study the healing of a GTR procedure, when it is combined with an immediate orthodontic tooth movement or used alone.
- Trial name
- NCT04896450
- Testing
- Guided tissue regeneration (GTR), Orthodontic tooth movement (OTM)
- Where
- Hungary
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Orthognathic Surgical Procedures, Three Dimensional (3D) Orthodontic Device
Accuracy of Three-Dimensional Soft Tissue Prediction Using Dolphin 3D Software in Patients With Mandibular Deformities Undergoing Orthognathic Surgery
This study aims to evaluate the accuracy of "Dolphin 3D" software for prediction of soft tissue changes in management of patients seeking orthognathic surgery to treat their mandibular deformities and collecting their feedback…
- Trial name
- NCT07557758
- Testing
- Dolphin 3D Software
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Healthy Subjects With Fixed Orthodontics
The Effect of Probiotic Lactobacillus Reuteri Prodentis Consumption on Gingival Crevicular Fluid Inflammatory Response and Metagenomic Profiles of Oral Microbiome in Orthodontic Patients.
In this study, researchers will test the effectiveness of probiotic consumption against oral pathogenic bacteria and reduce the occurrence of gingival inflammation in subjects using orthodontic fixed appliances (braces).
- Trial name
- NCT04847960
- Testing
- BioGaia Probiotic Lozenges
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Trisakti University
Orthopedic Disorder
Evaluation of Architectural Changes in Mandibular Bone Pattern After Functional Treatment by Fractal Dimension Analysis
In this study it was aimed to examine the changes in mandibular bone after functional treatment by using fractal dimension (FD) and cortical thickness (CT) analysis.
- Trial name
- NCT04730115
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Orthodontic Pathological Resorption of External Root, Orthodontic Appliance Complication
Photobiomodulation and Root Resorption
Objectives: The aim of this study is to investigate the effect of photobiomodulation therapies on root resorption compared with the placebo group. Materials and Methods: 30 patients, who were admitted to the ………….
- Conditions
- Orthodontic Pathological Resorption of External Root, Orthodontic Appliance Complication, Orthodontic Tooth Movement
- Trial name
- NCT04044989
- Testing
- Laser, light-emitting diode (LED)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Increased Overbite
Orthodontic Reduction of an Increased Overbite in Adolescents - the Mechanism and Rate of Occlusal Adaptation
The correction of a deep overbite is assumed to involve incisor intrusion and the extrusion or eruption of premolars and molars.
- Trial name
- NCT02925468
- Testing
- Bite turbo
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- NHS Tayside