Clinical trials: Orthodontic
Malocclusion
The Effects of Extraoral Photobiomodulation on the Rate of Orthodontic Alignment
The aim of this study is to determine if extraoral OrthoPulse®, which emits extraoral LED (Light Emitting Diode) photobiomodulation (PBM), reduces the time it takes to complete orthodontic alignment.
- Trial name
- NCT02267824
- Testing
- Extraoral OrthoPulse® PBM, Fixed Orthodontic Appliance Treatment
- Where
- 4 sites in United States, Canada and 1 more
- Volunteers
- 101 people
- Sponsor
- Biolux Research Holdings, Inc.
Malocclusion, Angle Class I
A Comparison Between GUMMETAL and SS Orthodontic Wires in Space Closure
When there is space present between our teeth orthodontically we have the ability to close them through many methods. Using braces as our treatment modality this study will be investigating how efficient a new orthodontic wire is…
- Trial name
- NCT04591080
- Testing
- GUMMETAL Orthodontic Wire, Stainless Steel (CrNi)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Inflammation of Mouth, Acute Mucous Inflammation
Efficacy of Anthocyanin Mouthrinse for Oral Anti-inflammation From Orthodontic Treatment
The purpose of this study is to compare the oral inflammatory reduction effect caused from orthodontic treatment of anthocyanin and placebo mouthrinse.
- Trial name
- NCT02536781
- Testing
- Anthocyanin
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Khon Kaen University
Malocclusion
Accelerated Invisalign Therapy in Conjunction With Acceledent Aura
Purpose: The objective of this study is to investigate the effects of accelerated Invisalign and vibration therapy on rate of orthodontic tooth movement, activation of inflammation biomarkers as well as pain levels experienced by…
- Trial name
- NCT02868554
- Testing
- AcceleDent Aura, Accelerated Invisalign therapy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of North Carolina, Chapel Hill
Canine Retraction
Characterizing Orthodontic Tooth Movement With Photographic Scans
Characterizing orthodontic tooth movements in real time by using photographic scans to monitor teeth movement. The photographic scans will also be compared to 3D model scans.
- Trial name
- NCT05780788
- Testing
- Monitoring Tooth Movement
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- UConn Health
Crowding of Teeth
The Evaluation Of The Efficiency Of Micro-osteoperforation
Prolonged orthodontic treatment increases the risc of caries, periodontal problems and root resorption. Many different techniques were developed to shorten the treatment time.
- Trial name
- NCT03652454
- Testing
- micro-osteoperforation, conventional fixed appliance treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Detachment of Glued Mandibular Post-orthodontic Restraints
Comparison of Bonding Failure Rates of Fixed Lingual Mandibular Retainers in a French Sample Aged 11 or Older, Comparing Prior Enamel Sandblasting With Conventional Pumice Polishing
At the completion of orthodontic treatment, the position of the mandibular canines and incisors is being maintained on a routine basis by bonding a multi-braided wire retainer onto their lingual surfaces.
- Trial name
- CONTORTHO (NCT03954145)
- Testing
- Enamel pumicing before bonding the lingual retainer., Enamel sandblasting before bonding the lingual retainer.
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Strasbourg, France
Malocclusion
Effect of Intra-Oral Photobiomodulation on Orthodontic Treatment Time
The aim of this study is to determine the effect of OrthoPulse™, an intra-oral LED (Light Emitting Diode) photobiomodulation device, on orthodontic treatment time.
- Trial name
- NCT02267850
- Testing
- Fixed Orthodontic Appliance Treatment, OrthoPulse™, Non-Functional OrthoPulse™
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Biolux Research Holdings, Inc.
Malocclusion
Clinical Performance of a New Esthetic, Self-ligating Orthodontic Bracket
A cohort of 15 patients starting orthodontic treatment with fixed appliances will receive EXD-952 Ceramic Self-ligating brackets on all mandibular incisors and a different type of brackets on the remaining mandibular teeth.
- Trial name
- NCT02959671
- Testing
- Lower Anterior EXD-952 Self-ligating Brackets
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Minnesota
Dental Caries
Caries Lesion Activity in Orthodontic Patients - Calcivis System
This is a prospective, single-centre clinical study to monitor caries lesion activity in orthodontic patients with the Calcivis System over a 12 week period.
- Trial name
- NCT02771522
- Testing
- Calcivis System
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Calcivis Ltd
Tooth Crowding, Dental Crowding
Analysis of Orthodontic Tooth Movement Using 3D Imaging
Purpose: This project aims to study the effects of wire dimension and ligation method (bracket type) on the first stage of orthodontic treatment using 3D imaging.
- Conditions
- Tooth Crowding, Dental Crowding, Malocclusion
- Trial name
- NCT03398798
- Testing
- .014", .016", Twin brackets
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Malocclusion
OrthoPulse™ and Its Effect on the Rate of Orthodontic Tooth Alignment: A Pilot Feasibility Study
The aim of this study is to determine the effect of OrthoPulse™, an intra-oral LED (Light Emitting Diode) photobiomodulation device, on the rate of anterior orthodontic alignment.
- Trial name
- NCT02267837
- Testing
- OrthoPulse™
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Biolux Research Holdings, Inc.
Retention, Compliance
Evaluation of Tailored Electronic Reminders on Compliance With Removable Orthodontic Retention
Participants will be recruited for inclusion at a routine adjustment appointment prior to planned removal of the appliances. Following removal of the appliances, consenting participants will be randomly allocated to one of two…
- Conditions
- Retention, Compliance, Orthodontic, Periodontal Health
- Trial name
- NCT03224481
- Testing
- Electronic reminder
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Orthodontic Appliance Complication
The Effect of Using Mobile Applications for Improving Oral Hygiene
The study aims to investigate the effect of the use of mobile phone application sending reminders to patients with orthodontic fixed appliances on oral hygiene.
- Trial name
- NCT03109769
- Testing
- Mobile phone application, Verbal oral hygiene instructions
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Dental Caries, Dental Plaque
Orthodontic Varnish Microbiology Study
Orthodontic treatment is common in teenagers, which typically involve the attachment of metal brackets to the teeth. These brackets often impede proper oral hygiene, leading to plaque accumulation and the development of white…
- Conditions
- Dental Caries, Dental Plaque, Dental White Spot
- Trial name
- NCT04528134
- Testing
- Extended Contact RMGI (Resin-modified Glass Ionomer) Varnish, 5% Sodium Fluoride Varnish
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Malocclusion
The Effect of OrthoPulse™ on the Rate of Orthodontic Tooth Movement
This open label study is designed to evaluate the ability of OrthoPulse™ to safely and effectively increase the rate of orthodontic tooth movement with fixed appliances.
- Trial name
- BX8RN (NCT02267811)
- Testing
- Orthodontic Treatment, OrthoPulse™
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Biolux Research Holdings, Inc.
Orthodontic Tooth Movement
Clinical Trial to Assess the Efficacy of Reducing the Aligners' Wear Protocol
The hypothesis of this project is that replacing the current 7-day wear protocol with a 3-day wear protocol, while integrating less tooth movement per aligner (reduce the amount of activation per aligner) may produce more…
- Trial name
- NCT05905224
- Testing
- Invisalign 7-day wear protocol, Invisalign 3-day wear protocol
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Florida
Orthodontic Appliance Complication
Effectiveness of Low Frequency Vibration on the Rate of Canine Retraction
The goal of this Randomized controlled clinical trial is To investigate the effectiveness of AcceleDent Aura vibrating device on rate of canine retraction in orthodontic treatment..
- Trial name
- NCT05818527
- Testing
- Acceledent vibrating device
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- mohamed abdelmotaleb
Orthodontic Retainers, Clinical Trial
Comparison of Modified Vacuum-formed Retainers Versus Hawley Retainer
This study will focus on the relapse of arch width in two types of retention regimes, which are modified vacuum-formed retainers and Hawley type retainers in patients after fixed appliance treatment in transverse arch expansion…
- Trial name
- NCT04237298
- Testing
- Modified vacuum-formed retainer covering the palete
- Where
- 3 sites in Malaysia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Malocclusion
Evaluation of a "Flash-free" Adhesive Resin for Orthodontic Bracket Bonding
The purpose of this study is to compare bonding time, bond survival, amount of adhesive remaining on the tooth surface after bracket debonding, and time required for adhesive remnant cleanup between a new "flash-free" and a…
- Trial name
- NCT02030002
- Testing
- APC Flash-Free Adhesive Coated Appliance System, APC II Adhesive Coated Appliance System
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Minnesota