Clinical trials: Organoids
Invasive Breast Cancer
Patient-Derived Breast Cancer Organoids for Therapeutic Extracellular Vesicle Isolation (PDO-Mercurial01)
The aim of this study is to establish organoid cultures, which are three-dimensional in vitro tumor models capable of supporting the long-term ex vivo growth of tumor cells derived from patients with breast carcinoma.
- Trial name
- PDO-Mercurial (NCT07421479)
- Testing
- Blood and tumor tissue collection
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Breast Cancer
Quadratic Phenotypic Optimisation Platform (QPOP) Utilisation to Enhance Selection of Patient Therapy Through Patient Derived Organoids in Breast Cancer
Based on proof-of-concept study, the investigators hypothesise that the QPOP prediction model can be further extended into use in solid tumors.
- Trial name
- QUEST (NCT05177432)
- Testing
- QPOP
- Where
- Singapore
- Volunteers
- 26 people
- Sponsor
- National University Hospital, Singapore
Organoids, Intrahepatic Cholangiocarcinoma
Clinical Transformation of Organoid Model to Predict the Efficacy of GC in the Treatment of Intrahepatic Cholangiocarcinoma
The clinical incidence of intrahepatic cholangiocarcinoma (ICC) is high and insidious, and the prognosis of advanced patients is poor.
- Trial name
- NCT05644743
- Testing
- gemcitabine + cisplatin
- Volunteers
- 40 people
- Sponsor
- Chengjun Sui,MD