Clinical trials: Oral Surgery
Vitiligo
The Value of Using Mini-oral Pulse Steroid Therapy Along With Non Cultured Epidermal Cell Suspension (NCES) in Stable Resistant Vitiligo
Assessing the additive value of mini-oral pulse steroid therapy in surgical treatment of acral and difficult to treat sites of vitiligo
- Trial name
- NCES (NCT06974669)
- Testing
- oral steroid-dexamethasone, non cultured epidermal suspension
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Submandibular Gland Tumor, Parotid Gland Tumor
Human Salivary Gland Disposition of Alda-341 in Patients Undergoing Salivary Gland Surgery
The purpose of this study is determine salivary gland disposition of d-limonene, the primary component in citrus peel and a common dietary supplement.
- Trial name
- NCT04296266
- Testing
- Alda-341
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Perioperative Nutrition
Clears On the Day of Anesthesia Permissible up to One-Hour Prior (CODA-POP) to Surgery
The purpose of this study is to assess whether residual gastric volumes in patients who receive clear liquids one hour prior to time of procedure is non-inferior compared to patients who are NPO past midnight, to compare…
- Trial name
- NCT06216977
- Testing
- Clear Liquids, Standard of Care
- Where
- United States
- Sponsor
- The University of Texas Health Science Center, Houston
Healthy, Inflammation
Cyclooxygenase Levels Following Surgery to Remove Third Molars (Wisdom Teeth)
This study will measure levels of an enzyme called cyclooxygenase in gum tissue following third molar (wisdom tooth) extraction. Cyclooxygenase is thought to contribute to pain that normally follows tissue injury or surgery.
- Trial name
- NCT00006175
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
PRF
Topical Application of PRF Before Radiation Therapy
The primary goal of this study is to observe whether PRP promotes the wound healing before a radiation therapy or not, compared to the natural healing of a tooth extraction socket.
- Trial name
- PRF (NCT06406530)
- Testing
- PRF, Natural Healing
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- University of Giessen
Periimplantitis
Evaluation of the Effects of the Low-level Laser Therapy as an Adjunct to Nonsurgical Treatment in Patients With Periimplantitis
The main objective of this study is to evaluate the clinical efficacy of low-level laser therapy (LLLT) in addition to non-surgical periodontal treatment in patients with peri-implantitis.
- Trial name
- NCT07128134
- Testing
- Low Level Laser Therapy, Non-surgical Periodontal Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Mustafa Kemal University
Basal Cell Carcinoma
A Study of Vismodegib With Surgery in Participants With Previously Untreated Basal Cell Carcinoma
This randomized, double-blind, placebo-controlled study will assess the efficacy and safety of vismodegib with surgery in participants with basal cell carcinoma.
- Trial name
- NCT01898598
- Testing
- Vismodegib
- Where
- 21 sites in United States
- Volunteers
- 18 people
- Sponsor
- Hoffmann-La Roche
Postoperative Ileus
Study of the Effect of Water Soluble Oral Contrast (Gastrografin) on Postoperative Ileus After Colorectal Surgery
The purpose of this trial is to determine whether the water-soluble contrast (gastrografin) is more effective in the treatment of postoperative ileus than the conventional one.
- Trial name
- NCT01440712
- Testing
- Gastrografin, physiological serum
- Where
- 3 sites in Spain
- Volunteers
- 58 people
- Sponsor
- Hospital Universitari de Bellvitge
Periodontal Diseases
Locally Delivered Melatonin Gel in Management of Stage II Grade B Periodontitis
Background: Periodontitis is a chronic inflammatory disease characterized by the destruction of tooth-supporting tissues, driven by an imbalance between bacterial pathogens and the host immune response.
- Trial name
- NCT07813936
- Testing
- 2% Melatonin gel
- Where
- Egypt
- Volunteers
- 23 people
- Sponsor
- Alexandria University
Cleft Lip, Cleft Palate
Primary Palatoplasty in Pediatric Patients - A Retrospective Review of Surgical Outcomes
Children who are born with cleft palate need surgery in order to correct the problem. The surgery is needed because the defect allows food to leak into the nose.
- Trial name
- NCT01380171
- Where
- United States
- Volunteers
- 1,295 people
- Sponsor
- Children's Healthcare of Atlanta
Gastric Cancer, Colon Cancer
Postoperative Oral Nutritional Supplementation After Major Gastrointestinal Surgery
Patients who underwent major gastrointestinal surgery is potentially at risk of malnutrition due to reduced oral intake, increased nutritional need, reduced gastrointestinal absorption function, and/or metabolic changes after…
- Conditions
- Gastric Cancer, Colon Cancer, Pancreatic Cancer, Duodenal Cancer
- Trial name
- NCT01838109
- Testing
- oral nutritional supplement
- Where
- South Korea
- Volunteers
- 174 people
- Sponsor
- Seoul National University Hospital
Fear, Dental
Validation of Universal Scale in Oral Surgery (USOS) for Patient's Psycho-emotional Status Rating
Patient's psycho-emotional status is being affected during various dental procedures causing patient's and doctor's discomfort. There are three basic factors, composing psycho-emotional status: fear, stress and pain sensitivity.
- Trial name
- NCT03165448
- Testing
- Pre-operative USOS scale testing, Pre-operative SDPQ, MDAS and VAS testing, Post-operative doctor's reported USOS
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Inesa Astramskaitė
Breast Cancer, Stage I Breast Cancer
Vorinostat in Treating Women Who Are Undergoing Surgery For Newly Diagnosed Stage I -III Breast Cancer
This phase II trial is studying how well vorinostat works in treating women who are undergoing surgery for newly diagnosed stage I, stage II, or stage III breast cancer.
- Conditions
- Breast Cancer, Stage I Breast Cancer, Stage II Breast Cancer, Stage III Breast Cancer
- Trial name
- NCT00262834
- Testing
- vorinostat, conventional surgery
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- National Cancer Institute (NCI)
Periodontal Diseases
Evaluation of Enamel Matrix Derivative as an Adjunct to Minimally Invasive Non-surgical Treatment of Intrabony Defects.
Aim: The aim of this prospective, randomized, parallel arm, blind, controlled clinical trial is to compare the clinical and radiographic outcomes following regenerative treatment of intrabony periodontal defects using a Minimally…
- Trial name
- NCT03622255
- Testing
- MINST, MINST with EMD
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Impacted Third Molar Tooth
Changes in Resistome After Dental Extraction and Amoxicillin.
The aim of this study is to evaluate the nature of the change in oral and gut bacterial resistance profiles after antibiotic therapy for a surgical procedure in two groups.
- Trial name
- NCT02830347
- Testing
- Amoxicillin, Extraction
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dental Implant, Dental Implant Failure
Fully Guided Dental Implant Placement and Primary Stability
The precision of dental implant placement is vital for long-term implant success. The surgical guide is designed using advanced 3D imaging techniques allows for a highly accurate simulation of the ideal implant position…
- Conditions
- Dental Implant, Dental Implant Failure, Peri Implantitis, Cone Beam Computed Tomography
- Trial name
- NCT07149987
- Testing
- All implant placements were performed exclusively in the maxillary region (upper jaw) to ensure a controlled comparison within the same anatomical area
- Where
- Iraq
- Volunteers
- 30 people
- Sponsor
- University of Mosul
Peri-Implantitis and Peri-implant Mucositis
Effectiveness of Zirconia Glaze Removal and Polish in the Treatment of Peri-implant Mucositis
This clinical trial is being conducted to study peri-implant mucositis (inflammation in the gums around dental implant that does not extend into the implant-supporting bone).
- Trial name
- NCT06619158
- Testing
- Crown modification
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University of Manitoba
Postoperative Pain, Facial Swelling
Aescin-Based Herbal Extract (Reparil) for Postoperative Sequelae After Mandibular Third Molar Surgery
This randomized, single-blind, controlled clinical trial aims to evaluate the efficacy and safety of Aescin-based herbal extract (Reparil®) compared with Ibuprofen in managing postoperative sequelae following surgical removal of…
- Conditions
- Postoperative Pain, Facial Swelling, Trismus
- Trial name
- Reparil (NCT07244029)
- Testing
- Escin, Ibuprofen 400 mg
- Where
- Oman
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
Dental Implant, Tooth Loss
Flap Vs Flapless Technique for Delayed Implant Placement in the Maxillary Esthetic Zone
This randomized comparative clinical trial aims to evaluate the clinical, radiographic, and esthetic outcomes of flap versus flapless techniques for delayed dental implant placement in the maxillary esthetic zone.
- Conditions
- Dental Implant, Tooth Loss, Partial Edentulism, Maxillary Tooth Loss
- Trial name
- NCT07654452
- Testing
- Flap Implant Placement, Flapless Implant Placement
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Bleeding
Nasal Desmopressin Versus Oral Bisoprolol for Controlling Bleeding During Endoscopic Sinus Surgery
Functional endoscopic sinus surgery (FESS) is well established for treatment of chronic rhinosinusitis and nasal polyps. Masking of the surgical field can lead to severe complication as tissue injury, increase post-operative…
- Trial name
- NCT05430048
- Testing
- nasal Desmopressin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University