Clinical trials: Opioid-Induced Constipation (OIC), open to volunteers
Opioid-Induced Constipation (OIC)
Safety and Pharmacokinetics Study of Naldemedine in Paediatric Participants Receiving Opioids
The primary objective of this study is to evaluate the pharmacokinetic (PK) profile of naldemedine and nor-naldemedine after a single oral dose of naldemedine in pediatric participants who are receiving or about to receive…
- Trial name
- NCT05588323
- Testing
- Naldemedine
- Where
- 16 sites in Albania, Armenia and 6 more
- Volunteers
- 24 people
- Sponsor
- Shionogi
Cancer, Opioid Induced Constipation (OIC)
Naldemedine in Clinical Practice in Cancer Patients With Opioid Induced CONstipation: Clinical Outcomes and Patient Experience
This study looks at how well a medicine called naldemedine works for people with cancer who become constipated while taking opioids. Opioids are medications prescribed to treat persistent or severe pain.
- Trial name
- NOCON (NCT07231796)
- Testing
- Naldemedine, an peripherally acting opioid antagonist
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Professor Monique A. H. Steegers