Clinical trials: Opioid Consumption
Total Knee Replacement, Post Operative Pain
Effect of Mindfulness on Pain After Total Knee Arthroplasty
This study will be a prospective randomized controlled trial evaluating the effectiveness of using Headspace before and after undergoing total knee replacement surgery.
- Conditions
- Total Knee Replacement, Post Operative Pain, Opioid Use
- Trial name
- NCT06118073
- Testing
- Headspace, Total Knee Replacement
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Upper Limb Surgery, Iliac Crest Bone Harvest
Transversalis Fascial Plane Nerve Block in Iliac Crest Bone Graft
Hand or wrist surgery often requires the use of bony material in order to accomplish any associated reconstructive aspects required for the surgery.
- Trial name
- NCT01133730
- Testing
- Active treatment
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University Health Network, Toronto
Obesity, Postoperative Pain
OFA vs OBA in Bariatric Surgery
This study compares two different anesthesia techniques in patients with obesity undergoing bariatric surgery: one that includes opioids (OBA), and one that avoids them completely (OFA).
- Conditions
- Obesity, Postoperative Pain, Bariatric Surgery, Opioid-free Anesthesia
- Trial name
- OFA VS OBA1 (NCT07075302)
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Hospital HM Nou Delfos
Postoperative Pain
Effect of Different Volumes of SPSIP Block in Breast Surgery
This randomized, double-blind study will compare the effectiveness of three different volumes of serratus posterior superior intercostal plane block for postoperative pain control in patients undergoing unilateral breast surgery…
- Trial name
- SPSIP-VOLUME (NCT07783386)
- Testing
- Bupivacaine 0.25% (20 mL), Bupivacaine 0.25% (30 mL), Bupivacaine 0.25% (40 mL)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa City Hospital
Pengblock, over65years
Comparıson Of The Effects Of Perıcapsulary Nerve Group Block (Peng Block) And Lumbar Erector Spına Plan Block (Lesp Block) On Postoperatıve Opıoıd Consumptıon
The aim is to demonstrate that lumbar ESP block provides more effective postoperative analgesia than PENG block in geriatric patients with hip fractures, and reduces postoperative opioid consumption more than PENG block
- Conditions
- Pengblock, over65years, Lumbar Erector Spinae Plane Block, Hipfracture
- Trial name
- NCT06995079
- Testing
- Postoperative pain assessment of patients who underwent block
- Volunteers
- 70 people
- Sponsor
- Sakarya University
Central Sleep Apnea, Secondary
Effect of Acetazolamide on Central Sleep Apnea Related to Opium Consumption
Acetazolamide improves central sleep apnea related to opium consumption.
- Trial name
- NCT02371473
- Where
- Iran
- Volunteers
- 12 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Postoperative Pain, Opioid Use
Erector Spinea Plane Block in Pediatric Hip Surgery
This prospective randomized controlled double-blind study will be carried out to evaluate the effect of ultrasound-guided erector spinae plane block on the postoperative analgesia in children after hip surgeries, the total…
- Trial name
- NCT04374396
- Testing
- Real ultrasound-guided single shot erector spinae plane block (ESP B)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Pain
Effect of Gabapentin Enacarbil on Opioid Consumption and Pain Scores
Opioids are effective analgesics, but cause side effects including sedation, respiratory depression, low blood pressure, nausea, and constipation.
- Trial name
- NCT02840240
- Testing
- Gabapentin enacarbil
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- The Cleveland Clinic
Knee Osteoarthritis, Total Knee Arthroplasty
Effect of Preoperative Cold Therapy on Early Postoperative Outcomes in Total Knee Arthroplasty
This prospective, single-center, randomized controlled trial investigates the effects of preoperative cold therapy on early postoperative outcomes in patients undergoing unilateral primary total knee arthroplasty (TKA).
- Conditions
- Knee Osteoarthritis, Total Knee Arthroplasty, Cryotherapy, Postoperative Pain Management
- Trial name
- NCT07134283
- Testing
- Preoperative and Postoperative Cold Therapy with Gel Cold Pack, Postoperative Cold Therapy with Gel Cold Pack
- Where
- Turkey (Türkiye)
- Volunteers
- 208 people
- Sponsor
- Ankara City Hospital Bilkent
Analgesia, Pain, Postoperative
Wound Infiltration With Tramadol, Dexmedetomidine, or Magnesium Plus Ropivacaine for Pain Relief After Spine Surgery
The rationale for multimodal analgesia is to achieve additive or synergistic analgesic properties while decreasing the incidence of side effects by reducing the dose of each agent.
- Conditions
- Analgesia, Pain, Postoperative, Spinal Stenosis, Spinal Disease
- Trial name
- NCT04391855
- Testing
- Tramadol with ropivacaine, Dexmedetomidine with ropivacaine, Magnesium with ropivacaine
- Where
- Greece
- Volunteers
- 72 people
- Sponsor
- Aristotle University Of Thessaloniki
Laparoscopic Cholecystectomy, Postoperative Quality of Recovery
Effect of Preoperative Melatonin on Quality of Recovery After Elective Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is one of the most commonly performed abdominal surgical procedures worldwide. Although the widespread implementation of Enhanced Recovery after Surgery (ERAS) protocols has improved perioperative…
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Quality of Recovery, Preoperative Anxiety, Postoperative Sleep Quality
- Trial name
- MEL-REC (NCT07553143)
- Testing
- Melatonin (N-acetyl-5-methoxytryptamine)
- Where
- Bangladesh
- Volunteers
- 84 people
- Sponsor
- Armed Forces Medical Institute Bangladesh
Arthropathy of Hip, Hip Arthropathy
Pericapsular Nerve Group (PENG) Block Combined With Lateral Femoral Cutaneous Nerve (LFCN) Block or Wound Infiltration for Postoperative Analgesia in Anterior Approach Total Hip Arthroplasty: A Randomized Controlled Trial
This prospective, randomized controlled trial aims to compare two multimodal regional anesthesia strategies for postoperative analgesia in elective total hip arthroplasty (THA) performed via anterior approach.
- Conditions
- Arthropathy of Hip, Hip Arthropathy, Locoregional Anesthesia, Complication of Anesthesia
- Trial name
- Peng_lfcn/WI (NCT07284615)
- Testing
- PENG plus LFCN block, PENG plus WI
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Ospedale Edoardo Bassini
Hip Osteoarthritis, Total Hip Arthroplasty (THA)
QIPB vs SI-FICB for Postoperative Analgesia After Total Hip Arthroplasty
Total hip arthroplasty (THA) causes moderate-to-severe postoperative pain. The PROSPECT guideline recommends the supra-inguinal fascia iliaca compartment block (SI-FICB) for THA, whereas evidence for newer…
- Conditions
- Hip Osteoarthritis, Total Hip Arthroplasty (THA), Postoperative Pain, Acute Pain
- Trial name
- NCT07683663
- Testing
- Supra-Inguinal Fascia Iliaca Compartment Block, Quadro-Iliac Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Dokuz Eylul University
Compartment Syndrome of Leg
Effects of Perioperative Patient Education Regarding Compartment Syndrome on Post-operative Opioid Consumption
This study is a prospective, randomized trial. Our study aims to study the effects of perioperative patient education about compartment syndrome on patients' perception of their own pain, amount of opioid medication utilization…
- Trial name
- NCT03359031
- Testing
- Patient education
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Rothman Institute Orthopaedics
Postoperative Pain
Comparison of SE-TAP, M-TAPA, and Rectus Sheath Block in Abdominal Surgeries
The aim of this randomised controlled study is to compare the effects of three different fascial plane block [subcostal exterior semilunaris transverses abdominis plane (SE-TAP) block, modified thoracoabdominal nerves block…
- Trial name
- NCT05259345
- Testing
- Bilateral SE-TAP, Bilateral M-TAPA, Bilateral RSB
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Inonu University
MeSH C23.300.707.374.875, MeSH E01.370.388.250.520
Comparing Two Nerve Block Methods for Pain Relief in Laparoscopic Hernia Surgery
After inguinal hernia repair, patients having chronic pain approximately 20 percent. If patients don't have postoperatively acute pain, they will tend to have less chronic pain.
- Conditions
- MeSH C23.300.707.374.875, MeSH E01.370.388.250.520, MeSH E03.155.086.711, MeSH C23.550.767.700
- Trial name
- NCT07676123
- Testing
- Anterior Quadratus Lumborum Block, Ilioinguinal-Iliohypogastric Block
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ankara University
Postoperative Pain
Effects of TAP and QLB-1 Blocks on Opioid Consumption
Laparoscopic cholecystectomy is associated with less pain than open surgery and a shorter recovery time. While the type of pain experienced after laparoscopy differs from that experienced after laparotomy, it is predominantly…
- Trial name
- NCT06663345
- Testing
- Transversus Abdominis Plan Block (TAPB), Lateral Quadratum Lumborum (QLB-1) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Pain, Postoperative
Erector Spinae Plane Block Analgesia for Lumbar Spine Fusion Surgery
The purpose of this study was to investigate the effect of a bilateral ultrasound guided erector spinae plane block on the pain scores and opoid utiliziation in fusion surgery of the lumbar spine.
- Trial name
- NCT04749095
- Testing
- Erector spinae plane block
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Benha University
TURP(Transurethral Resection of Prostate)
Sacral Erector Spinae Plane Block in Transurethral Prostate Resection Surgery
The aim of this study is to investigate the effects of bilateral sacral erector spinae plane block on hemodynamic values, postoperative pain, analgesic use and patient satisfaction during operative period in Transurethral…
- Trial name
- NCT06962085
- Testing
- sacral erector spinae plane block group, Opioid Analgesics
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Adiyaman University
Postoperative Pain
Transversalis Fascia Plane Block Versus Low-Dose Intrathecal Morphine for Open Inguinal Hernia Repair
Open inguinal hernia repair is commonly associated with early postoperative pain, which may delay mobilization, reduce patient satisfaction, and increase opioid consumption.
- Trial name
- NCT07695935
- Testing
- Intrathecal morphine, Ultrasound-guided transversalis fascia plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hitit University