Clinical trials: Open Nephrectomy
Analgesic Efficacy, External Oblique Intercostal Block
Analgesic Efficacy of External Oblique Intercostal Block vs Subcostal Transversus Abdominis Plane Block in Open Surgical Nephrectomy
To compare the efficacy of unilateral ultrasound-guided oblique subcostal transversus abdominis plane block with unilateral ultrasound-guided external oblique intercostal plane block in providing intraoperative and postoperative…
- Conditions
- Analgesic Efficacy, External Oblique Intercostal Block, Subcostal Transversus Abdominis Plane Block, Open
- Trial name
- NCT06584695
- Testing
- Transversus abdominis plane block, External Oblique Intercostal Plane Block, Control group
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Cairo University
Renal Cancer
Open vs Robotic Assisted Partial Nephrectomy
To demonstrate that Robotic-Assisted partial nephrectomy is superior to Open partial nephrectomy in reducing the number of 30 day post-operative complications (Clavien-Dindo Type I-V) for patients with intermediate to high…
- Trial name
- OpeRa (NCT03849820)
- Testing
- Robotic-assisted partial nephrectomy, Open partial nephrectomy
- Where
- 12 sites in Germany
- Volunteers
- 247 people
- Sponsor
- Intuitive Surgical
Transversus Abdominis Plane Block, External Oblique Intercostal Plane Block
Transversus Abdominis Plane Block Versus External Oblique Intercostal Plane Block for Postoperative Analgesia in Pediatrics Undergoing Open Nephrectomy
The aim of this study is to compare the ultrasound guided TAP Block and EOIP block for postoperative analgesia in pediatrics undergoing open nephrectomy.
- Conditions
- Transversus Abdominis Plane Block, External Oblique Intercostal Plane Block, Postoperative Analgesia, Pediatrics
- Trial name
- NCT06452225
- Testing
- External Oblique Intercostal Plane Block, Transversus Abdominis Plane Block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Metastatic Renal Cell Carcinoma ( mRCC)
Immediate Versus Deferred Cytoreductive Nephrectomy With Ipilimumab/Nivolumab in mRCC
The goal of this clinical trial is to learn whether the timing of surgery (cytoreductive nephrectomy) improves outcomes when combined with immunotherapy (ipilimumab and nivolumab) in adults with metastatic clear cell renal cell…
- Trial name
- IVE in mRCC (NCT07233668)
- Testing
- Ipilimumab plus Nivolumab, Cytoreductive Nephrectomy
- Volunteers
- 172 people
- Sponsor
- Seoul National University Hospital
Renal Cell Carcinoma
Study of Sunitinib in Subjects With High Risk Renal Cell Carcinoma
This study is designed to explore the molecular modulatory effect of Sunitinib when given in a neoadjuvant setting prior to radical or partial nephrectomy.
- Trial name
- NCT01070186
- Testing
- Sunitinib, Tumor biopsy, Nephrectomy
- Sponsor
- Jonsson Comprehensive Cancer Center
Trifecta Achievement, Pentafecta Achievement
Trifecta Achievement in Open and Laparoscopic Partial Nephrectomy
Background: Partial nephrectomy (PN) is a reference standard for the management of the cT1 renal mass, primarily due to better preservation of renal function.
- Trial name
- Trifecta (NCT06960135)
- Testing
- open partial nephrectomy, laparoscopic partial nephrectomy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- South Valley University
Renal Masses
Comparison of OpeN VErsus RoboTic Partial Nephrectomy
A prospective randomized controlled feasibility trial for patients undergoing partial nephrectomy for T1 renal masses at Princess Margaret. Participants will be randomized receive either open or robotic partial nephrectomy.
- Trial name
- CONVERT (NCT04011891)
- Testing
- Robotic Partial Nephrectomy, Open Partial Nephrectomy
- Where
- Canada
- Sponsor
- University Health Network, Toronto
Renal Transplant Donor of Left Kidney
Enhanced Recovery Open Versus Laparoscopic Donor Nephrectomy
A phase III randomized trial conducted to compare recovery outcomes between laparoscopic and open donor nephrectomy within a specified enhanced recovery protocol
- Trial name
- MEnROL (NCT02699489)
- Testing
- Laparoscopic donor nephrectomy, Open donor nephrectomy
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Erector Spinae Plane Block, Thoracic Epidural Analgesia
Ultrasound-guided Continuous Erector Spinae Plane Block Versus Thoracic Epidural Analgesia in Open Nephrectomy
There are different case studies about the use of erector spinae block (ESPB ) in nephrectomy, but there are no enough randomized controlled studies about it until now so it will be one of the earliest studies that investigate…
- Conditions
- Erector Spinae Plane Block, Thoracic Epidural Analgesia, Nephrectomy
- Trial name
- NCT04947644
- Testing
- Thoracic epidural analgesia, Ultrasound guided continuous erector spinae plane block
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- National Cancer Institute, Egypt
Postoperative Pain
Effects of Perioperative Intravenous Lidocaine and Ketamine on Acute and Chronic Pain After Open Nephrectomy
Open nephrectomy is one of the most common surgical procedures in urologic practice. Pain after surgery remains a significant clinical problem as it impairs recovery adversely and may lead to the transition to chronic pain.
- Trial name
- NCT02653651
- Testing
- Ketamine, Lidocaine
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Tunis El Manar
Subtransverse Interligamentary Block, Thoracic Paravertebral Block
Ultrasound-Guided Subtransverse Interligamentary Block Versus Thoracic Paravertebral Block for Postoperative Analgesia in Patients Undergoing Open Nephrectomy
This study aims to compare ultrasound-guided subtransverse process interligamentary (STIL) block versus thoracic paravertebral block (TPVB) for postoperative analgesia in patients undergoing open nephrectomy.
- Conditions
- Subtransverse Interligamentary Block, Thoracic Paravertebral Block, Postoperative Analgesia, Open Nephrectomy
- Trial name
- NCT07138794
- Testing
- Subtransverse process interligamentary, Thoracic paravertebral block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Regional Blocks, Renal Surgery
Preoperative Versus Postoperative Quadratous Lunborum Block in Nephrectomy
A multimodal analgesia regimen is suggested after nephrectomy, although some patients still report agonising pain. Regional anesthesia approaches may improve postoperative pain management and reduce the requirement for opioids…
- Trial name
- NCT05860309
- Testing
- quadratous lumborum block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Kidney Neoplasms
Prospective Randomized Study Comparing Laparoscopic Versus Open Partial Nephrectomy
Partial nephrectomy is considered the standard treatment for renal tumors smaller than 7 cm. With the evolution of image diagnostic tools and dissemination of its use, smaller tumors are being commonly diagnosed and treated.
- Trial name
- NCT01809119
- Testing
- Partial nephrectomy
- Where
- Brazil
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Renal Cell Carcinoma
The Intrathecal Morphine for Nephrectomy
To evaluate the efficacy and the safety of the intrathecal morphine injection in the open nephrectomy.
- Trial name
- EMPON (NCT01997788)
- Testing
- The intrathecal morphine injection, The intravenous patient-controlled analgesia, Demerol on demand
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Seoul National University Hospital
Renal Cancer, Partial Nephrectomy
Complications Associated With Partial Nephrectomy for Renal Cancer
This paper evaluates the initial complications and the complications two years postoperatively necessitating re-hospitalisation for three surgical procedures for renal tumour partial nephrectomy .
- Trial name
- NCT05168761
- Testing
- partial nephrectomy
- Volunteers
- 7,664 people
- Sponsor
- Central Hospital, Nancy, France
Tumor, Nephrectomy
Laparoscopic Versus Open Partial Nephrectomy - Surgical and Oncological Outcomes
Partial Nephrectomy is the standard care for small (<4 cm) renal tumors. Despite the expanding use of laparoscopic approach, debate exist regarding the short and long term outcomes compared to the open approach.
- Conditions
- Tumor, Nephrectomy, Laparoscopy
- Trial name
- LapVsOpen prtn (NCT01093079)
- Testing
- Laparoscopic partial nephrectomy, Open partial nephrectomy
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rabin Medical Center
Postoperative Pain, Open Nephrectomy
Modified External Oblique Intercostal Plane Block Versus Erector Spinae Plane Block for Open Nephrectomy
This prospective, randomized, assessor-blinded clinical trial aims to compare the postoperative analgesic efficacy of ultrasound-guided Erector Spinae Plane Block (ESPB) and Modified External Oblique Intercostal Plane Block…
- Trial name
- EOIPB-ON (NCT07726550)
- Testing
- Erector Spinae Plane Block, Modified External Oblique Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Namik Kemal University
External Oblique Intercostal Plane Block, Transversus Abdominis Plane Block
External Oblique Intercostal Plane Block Versus Transversus Abdominis Plane Block for Postoperative Analgesia in Adult Patients Undergoing Open Nephrectomy
The aim of this study is to compare external oblique intercostal plane (EOIP) block and ultrasound guided transversus abdominis plane (TAP) Block for postoperative analgesia in adult patients undergoing open nephrectomy.
- Conditions
- External Oblique Intercostal Plane Block, Transversus Abdominis Plane Block, Postoperative Analgesia, Nephrectomy
- Trial name
- NCT06452238
- Testing
- External Oblique Intercostal Plane Block, Transversus Abdominis Plane Block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Wilms Tumor, Renal Cancer
Nephrogreen. Appearances of Exvivo Renal Tumours Under Near-infrared
Indocyanine Green (ICG) is a dye which fluoresces under near-infrared (NIR) light. It has been used for several applications in adult surgery.
- Trial name
- Nephrogreen (NCT05735977)
- Testing
- Indocyanine Green (ICG)
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Birmingham Women's and Children's NHS Foundation Trust
Hemostatic Techniques, Nephrectomy
Safety and Hemostatic Efficacy of Fibrin Fleece in Partial Nephrectomy
This is a prospective, randomized, single blind, standard care- controlled study, which will include a total of 30 patients divided into two treatment arms: First are: patents who will be treated in accordance with standard of…
- Trial name
- Fleece (NCT00598130)
- Testing
- Fleece
- Where
- 4 sites in Israel
- Volunteers
- 30 people
- Sponsor
- OMRIX Biopharmaceuticals