Clinical trials: Oocyte Cryopreservation
Infertility, Female, Deferred Childbearing
Investigational Oocyte Cryopreservation for Medical and Non Medical Indications
This is a prospective study to assess the long term benefits and outcomes of the existing oocyte cryopreservation methods for fertility preservation in women with a potential medical or non medical risk of loss of fertility
- Trial name
- NCT04616417
- Testing
- Investigational Oocyte Cryopreservation
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Ovarian Hyperstimulation Syndrome, Infertility Drugs
Transfer of Fresh Versus Frozen/Thawed Embryos in IVF Cycles Where GnRH Agonist is Utilized for Oocyte Maturation.
It has been suggested that in IVF cycles where GNRH agonist is utilized for final oocyte maturation in patients at risk of ovarian hyperstimulation, pregnancy rates are reduced.
- Conditions
- Ovarian Hyperstimulation Syndrome, Infertility Drugs, Female
- Trial name
- NCT00365027
- Testing
- Delayed embryo transfer
- Sponsor
- HaEmek Medical Center, Israel
Oocyte Cryopreservation
Oocyte Cryopreservation Registry (HOPE Registry)
Phase IV, prospective multicenter, observational Registry will track cycle outcomes for subjects who are thawing frozen oocytes for subsequent use through in vitro fertilization (IVF) and embryo transfer (ET)
- Trial name
- NCT00699400
- Where
- 15 sites in United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- EMD Serono
Breast Cancer
Risk of Infertility Related to Adjuvant Chemotherapy for Early Breast Cancer: Oocyte/Embryo Cryopreservation
The aim of the study is to perform a French multicenter prospective interventional study in order to assess the feasibility and safety of ovarian hyperstimulation for oocyte / embryo cryopreservation in young women with breast…
- Trial name
- CHACRY (NCT02871167)
- Testing
- Controlled ovarian hyperstimulation (COH), Oocyte/embryo freezing
- Where
- 28 sites in France
- Volunteers
- 140 people
- Sponsor
- Centre Oscar Lambret
Fertility Preservation
Follicular Flushing Versus Direct Aspiration in Transabdominal Oocyte Retrieval
The goal of this observational study is to learn whether rinsing the egg sacs (follicles) during egg collection helps doctors collect more eggs in women with low egg reserve.
- Trial name
- NCT07877025
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Centrum Clinic IVF Center
Infertility
Randomized Controlled Trial Comparing Slow-freezing to Vitrification of Oocytes
Preservation of fertility is limited. Current methods include embryo cryopreservation and while still experimental, ovarian cryopreservation.
- Trial name
- NCT00777387
- Testing
- slow-freeze, vitrification
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
ART, Child Development
Cognitive, Emotional, Communicative, and Motor Development in Children Born From IOC
The study focuses on children born after in vitro fertilization (IVF) of cryopreserved oocytes.
- Trial name
- NCT05906966
- Testing
- Phone contact
- Where
- Italy
- Volunteers
- 377 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Cancer
Oocyte Cryopreservation Study (Egg Banking)
Women of reproductive age who seek to freeze eggs for future pregnancy attempts may be eligible to participate in a study investigating pregnancies that result from frozen eggs.
- Trial name
- NCT02396095
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Elective Egg Freezing, Oocyte Cryopreservation
Decision Aid for Elective Egg Freezing
The goal of this clinical trial is to evaluate whether a culturally tailored decision aid can improve decision-making and clinical outcomes for Taiwanese women considering elective egg freezing.
- Conditions
- Elective Egg Freezing, Oocyte Cryopreservation, Decision Aid, Egg Freezing
- Trial name
- DAEEF (NCT07543445)
- Testing
- elective egg freezing decision aid
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Oncological Disease, Fertility Preservation
Ovarian Tissue Cryopreservation Combined With Oocyte Cryopreservation Versus Oocyte Cryopreservation Alone
Fertility preservation is a crucial aspect of care for oncological patients undergoing gonadotoxic treatments such as chemotherapy, radiotherapy, or surgery, which can significantly reduce ovarian reserve and cause infertility or…
- Trial name
- NCT07546123
- Where
- Italy
- Volunteers
- 127 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Infertility, Egg Freezing
Egg Freezing Pilot Study
University Reproductive Associates is conducting a pilot study to study the technique of egg freezing. Your participation in this study will provide us with important information to allow us to offer this technology for women…
- Trial name
- NCT00839839
- Testing
- Oocyte Vitrification
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University Reproductive Associates
Fertility Issues, Reproductive Issues
The Stanford Egg Freezing Study
The purpose of this study is to see if the investigators can obtain non-inferior clinical outcomes (similar numbers of oocytes) using the Cardinal protocol, a cost-conscious, low-intensity egg freezing protocol, compared to other…
- Trial name
- NCT05842070
- Testing
- Low-Intensity Egg Freezing Protocol, High-Intensity Egg Freezing Protocol
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Stanford University
Fertility
Effect of Oocyte Vitrification on Fertilization Rate, Embryo Quality and Development
Indications for oocyte (egg) vitrification (fast freezing) include the preservation of reproductive competence of young cancer patients who need chemotherapy, pelvic radiation, or surgical removal of ovaries for treatment.
- Trial name
- NCT01422395
- Testing
- Freezing
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Main Line Fertility Center
Breast Cancer
Safety of Ovarian Stimulation With Letrozole and Gonadotropins in Breast Cancer Patients
Breast cancer patients are commonly treated with drugs that eggs present in the ovary and may reduce their chance for getting pregnant.
- Trial name
- NCT00504699
- Testing
- Ovarian stimulation in vitro fertilization cryopreservation
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- New York Medical College
Anxiety
The Effectiveness of Virtual Reality on Anxiety Reduction in Women Undergoing Elective Egg Cryopreservation.
A randomized trial assessing the effectiveness of virtual reality exposure prior to an oocyte retrieval procedure in terms of anxiety level .
- Trial name
- VRFORANXIETY (NCT06280222)
- Testing
- The VR instrument - Oculus Quest 2
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Infertility
Clinical Pregnancies After Cryopreservation of Donor Oocytes With an Open or Closed Device
This randomized pilot study will assess if there is a difference in clinical pregnancies using donor oocytes cryopreserved in either a closed or a semi-closed vitrification device.
- Trial name
- NCT02940106
- Testing
- Cryotop device, CBSvit device
- Where
- Belgium
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility, Infertility, Female
Effect of Vitrification and Warming Media on Pregnancy Rates in the Context of Oocyte Donation
Vitrification has become the gold standard for oocyte and embryo cryopreservation. Several commercial kits are available on the market, some are designed for specific developmental stages (e.g.
- Trial name
- NCT07288866
- Testing
- Vitrification and warming media for oocyte vitrification
- Where
- France
- Volunteers
- 111 people
- Sponsor
- University Hospital, Clermont-Ferrand
Procedure-Related Pain, Acute Pain
Virtual Reality Intervention to Reduce Pain in Women Undergoing Elective Oocyte Cryopreservation
This randomized controlled study evaluates whether exposure to relaxing virtual reality (VR) scenery prior to oocyte retrieval can reduce pain in women undergoing elective oocyte cryopreservation.
- Trial name
- OPU-VR (NCT07484815)
- Testing
- Virtual reality relaxation intervention, Standard Care Control
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Breast Cancer Female
Combining Interventions of Fertility Preservation to Mitigate Fertility Loss After Breast Cancer
This clinical prospective randomised controlled trial will evaluate the impact of an ovarian biopsy on the oocyte yield after controlled ovarian stimulation before chemotherapy in view of breast cancer.
- Trial name
- Coimbra (NCT04586686)
- Testing
- Ovarian biopsy via laparoscopy, Transvaginal oocyte retrieval
- Where
- 2 sites in Belgium
- Volunteers
- 41 people
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility, Female, Infertility
Use of Clomiphene Citrate as an Inhibitor of Ovulation in an Oocyte Cryopreservation Cycle
In vitro fertilization (IVF) has helped countless couples conceive where they otherwise were unable, but does come at a significant cost.
- Trial name
- CCOI (NCT05866068)
- Testing
- Clomiphene
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Neil Chappell