Clinical trials: Onychomycosis of Toenails
Onychomycosis of Toenail
A Phase 2 Study to Assess the Effectiveness of Topical Terbinafine in Participants With Mild to Moderate Onychomycosis of the Toenails
Onychomycosis is a fungal infection of the toenail caused by a range of organisms, including dermophytes, non-dermophyte molds, and yeasts.
- Trial name
- NCT07382427
- Testing
- 2.4% Topical Terbinafine, 10% Topical Efinaconazole, Vehicle Control
- Volunteers
- 200 people
- Sponsor
- Onyx Axiom
Onychomycosis of Toenails
A Clinical Investigation to Evaluate the Safety and Performance of a Treatment Kit for Ingrowing Toenail
This purpose of this study is to evaluate the safety and performance of a treatment kit for ingrowing toenail, primarily by determining the number of subjects who show a reduction in the severity of their ingrowing toenail.
- Trial name
- NCT02131363
- Testing
- Ingrowing Toenail Treatment Kit
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Infected Toenails, Onychomycosis
PinPointe FootLaser for the Treatment of Onychomycosis
To evaluate the safety and efficacy of the PathoLase FootLaser treatment of infected toenails.
- Trial name
- NCT00935649
- Testing
- PinPointe FootLaser
- Where
- 4 sites in United States, Canada
- Volunteers
- 134 people
- Sponsor
- PathoLase, Inc.
Onychomycosis of Toenails
Study in Patients With Onychomycosis Treated With Mycoclear® and Ciclopirox
The goal of this study is to learn about the effectiveness and safety of two products, ciclopirox or Mycoclear®, in treating fungal infections.
- Trial name
- NCT06971341
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Bologna
Onychomycosis of Toenails
Evaluation of the Performance of a Fungal Nail Treatment on the Visual Signs of Onychomycosis
This is a prospective, open label, non-comparative clinical investigation to evaluate the performance of a Fungal Nail Treatment on the visual signs of onychomycosis.
- Trial name
- NCT02546258
- Testing
- A Fungal Nail Treatment
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Onychomycosis of Toenails
Efficacy and Safety Evaluation of AN2690 Topical Solution to Treat Onychomycosis of the Toenail
The purpose of this study is to determine whether AN2690 topical solution is a safe and effective treatment for onychomycosis of the toenail.
- Trial name
- NCT01270971
- Testing
- AN2690 Topical Solution, 5%, Solution Vehicle
- Where
- 27 sites in United States
- Volunteers
- 594 people
- Sponsor
- Pfizer
Onychomycosis
Safety and Efficacy Study of Subjects With Onychomycosis of the Great Toenail
The purpose of the study is to determine the safety and efficacy of 5.0% and 7.5% AN2690 Solution in the treatment of distal, subungual onychomycosis of the great target toenail.
- Trial name
- NCT00679523
- Testing
- AN2690 Solution, 5.0%, AN2690 Solution, 7.5%
- Where
- 9 sites in Mexico
- Volunteers
- 60 people
- Sponsor
- Pfizer
Onychomycosis
Safety and Efficacy Evaluation of Topically Applied AN2690 Solutions for Subjects With Onychomycosis
The purpose of the study is to determine the safety and efficacy of 1% and 5% AN2690 solutions in the treatment of distal, subungual onychomycosis of the great toenail.
- Trial name
- NCT00680134
- Testing
- AN2690
- Where
- 7 sites in United States
- Volunteers
- 60 people
- Sponsor
- Pfizer
Onychomycosis
Diode Laser Treatment of Onychomycosis
The purpose of this study is to evaluate the V-Raser diode laser system with investigational Nail Fungus Handpiece in the treatment of onychomycosis.
- Trial name
- NCT01452490
- Testing
- Diode Laser Treatment
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- ConBio, a Cynosure Company
Onychomycosis
A Study to Evaluate the Efficacy and Safety of Oral VT-1161 in Patients With Onychomycosis of the Toenail
Several properties of VT-1161 suggest that it might be a safer and more effective treatment for onychomycosis of the toenail (also known as toenail fungus) than other oral antifungal medicines.
- Trial name
- NCT02267356
- Testing
- VT-1161
- Where
- 33 sites in United States
- Volunteers
- 259 people
- Sponsor
- Viamet
Tinea Unguium, Onychomycosis
Systemic Uptake of Diclofenac Sodium in Combination With Miconazole as Antifungal Nail Gel When Applied Daily With Monitoring of Hepatic and Renal Enzymes, and Serum Levels of Diclofenac 12 Hours After Application, and at 3 and 6 Months Study
Study evaluates these take of diclofenac sodium when used in conjunction with miconazole and urea as a topical antifungal nail gel treatment for onychomycosis.
- Trial name
- NCT04341402
- Testing
- Antifungal Nail Gel Study
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- William N Handelman
Onychomycosis of Toenail
A Study to See if Low Level Laser Light Can Help to Treat Toenail Fungus
The purpose of this study is to determine whether low level laser therapy (LLLT) using the Erchonia LunulaLaser device is effective in clearing toenails with onychomycosis.
- Trial name
- NCT03066336
- Testing
- Erchonia LunulaLaser
- Where
- United States
- Sponsor
- Erchonia Corporation
Onychomycosis of Toenail
Safety, Tolerability and Efficacy of Trichostatin A in Patients With Mild to Severe Onychomycosis
This is a multicenter, open label study designed to evaluate the safety, tolerability, and efficacy of topically administered VTR-297 solution.
- Trial name
- NCT07065773
- Testing
- Trichostatin A
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- Vanda Pharmaceuticals
Onychomycosis
TDT 067 Open Label Multi-Dose Onychomycosis Study
The aim of this study is to establish a clinical bridge to Lamisil® tablets by conducting a clinical pharmacokinetic (PK) study comparing the systemic exposure of a Lamisil® tablet with that of with TDT 067 under maximal use…
- Trial name
- NCT01790165
- Testing
- TDT067 and Lamisil
- Volunteers
- 27 people
- Sponsor
- Celtic Pharma Development Services
Mild to Moderate Onychomycosis Due to Dermatophyte
Phase IV Clinical Trial to Evaluate the Efficacy and Safety of Jublia® in Mild to Moderate Toenail Onychomycosis
The antifungal efficacy and safety of Jublia® topical solution will be assessed through an administration for 48 weeks to patients diagnosed with a mild or moderate onychomycosis due to dermatophyte.
- Trial name
- NCT03280927
- Testing
- Jublia®
- Where
- South Korea
- Volunteers
- 97 people
- Sponsor
- Dong-A ST Co., Ltd.
Onychomycosis of Toenail
Light Therapy for Onychomycosis Study
This is a pilot prospective study designed to capture information about the safety and effectiveness of the ToeFX Therapy Light.
- Trial name
- NCT05139888
- Testing
- Single wavelength light (red) only, Dual wavelength light (red/blue)
- Where
- Canada
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- ToeFX Inc.
Onychomycosis
Resin vs. Amorolfine vs. Terbinafine Treatment in Onychomycosis
The current study is conducted to corroborate the previous observational clinical trial with more valid methods and a more clinically relevant experimental design.
- Trial name
- NCT01851590
- Testing
- Resin Lacquer, Amorolfine, Terbinafine
- Where
- 2 sites in Finland
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Onychomycosis
Study to Evaluate the Efficacy and Safety of P-3058 10% Nail Solution in the Treatment of Toenail Onychomycosis
The purpose of this study is to determine whether P-3058 nail solution is a safe and effective treatment for onychomycosis.
- Trial name
- NCT02549001
- Testing
- P-3058 10%, vehicle of P-3058 10%, amorolfine 5%
- Where
- 13 sites in Belgium, Bulgaria and 11 more
- Volunteers
- 953 people
- Sponsor
- Polichem S.A.
Onychomycosis of Toenail
Effect of the Erchonia® LunulaLaser™ for the Treatment of Toenail Onychomycosis
The purpose of this clinical study is to demonstrate the efficacy of the Erchonia LunulaLaser™, for the treatment of onychomycosis of the toenail.
- Trial name
- NCT06006455
- Testing
- Erchonia LunulaLaser
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Erchonia Corporation
Onychomycosis
Efficacy and Safety of RV4104A Ointment in Onychomycosis
The purpose of the study is to evaluate the efficacy of RV4104A ointment versus bifonazole-urea ointment for the complete removal of the clinically infected nail plate area in patients with toenail onychomycosis.
- Trial name
- NCT00808366
- Testing
- Keratolytic/Antifungal
- Where
- France
- Volunteers
- 228 people
- Sponsor
- Pierre Fabre Dermo Cosmetique