Clinical trials: One-Lung Ventilation
One Lung Ventillation (OLV), Erector Spina Plan Block
Effect of Erector Spinae Plane Block on Cerebral Oxygenation During One-Lung Ventilation
The aim of this study is to evaluate the effect of the erector spinae plane block, used to reduce postoperative pain, on cerebral oxygenation in thoracic surgery patients undergoing one-lung ventilation in the lateral decubitus…
- Conditions
- One Lung Ventillation (OLV), Erector Spina Plan Block, Near Infrared Spectroscopy, Cerebral Desaturation
- Trial name
- NCT07432230
- Testing
- Erector Spinae Plane Block, A preoperative erector spinae plane block will not be administered
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Kayseri City Hospital
Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease
Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on pulmonary resistance (sPAP/CO) and other hemodynamic outcomes in patients with pulmonary arterial hypertension PAH, who live permanently…
- Conditions
- Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease, High Altitude, Echocardiography
- Trial name
- NCT07804524
- Testing
- Descent from 2850m to sea level
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Silvia Ulrich Somaini
One-Lung Ventilation, Thoracic Surgery
The Effect of Anesthesia on Cerebral Oxygenation
One-lung ventilation (OLV) may cause negative changes in the oxygenation of cerebral tissue which results in postoperative cognitive dysfunction.
- Conditions
- One-Lung Ventilation, Thoracic Surgery, Postoperative Cognitive Complications
- Trial name
- NCT04760262
- Testing
- Sevoflurane, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Thoracic, Diseases
The Effect of Two Airway Interventions, During One Lung Ventilation, on Blood Oxygen Content
Patients requiring one lung ventilation (OLV) for open thoracic surgery will be ventilated (breathing performed by a breathing machine) during anesthesia using a lung protective ventilation strategy (small breath volumes at…
- Trial name
- NCT01495936
- Testing
- RM + Positive End Expiratory Pressure, Continuous Positive Airway Pressure
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lung Protective Ventilation, Cardiopulmonary Bypass
Unilateral Ventilation on Cardiopulmonary Bypass During Cardiac Surgery
This study investigates if single lung ventilation on cardiopulmonary bypass can mitigate postoperative lung water accumulation determined by lung ultrasound in the ventilated lung as compared to the non-ventilated lung in…
- Conditions
- Lung Protective Ventilation, Cardiopulmonary Bypass, High-risk Cardiac Patients, Lung Ultrasound
- Trial name
- NCT07612709
- Testing
- Ventilated lung, Non-ventilated lung.
- Where
- Austria
- Volunteers
- 45 people
- Sponsor
- Medical University of Vienna
Thoracic Surgery
Pressure-Controlled vs Volume-Controlled Ventilation During One Lung Ventilation
Compared with the information available in sepsis and trauma-associated ARDS, less is known about the cause and pattern of lung injury after thoracic surgery. Definition of lung injury in this context is difficult.
- Trial name
- NCT00975468
- Testing
- Pressure Controlled vs. Volume Controlled Ventilation during OLV
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- King Faisal University
Thoracic Surgery, One Lung Ventilation
Insertion Depth of Left-sided Double-lumen Tube: a New Predictive Formula
The authors developed a formula for predicting the accurate depth of DLT insertion into the appropriate bronchus based on height as follows [The predicted insertion depth of left DLT (cm) equals 0.249 × (BH)0.916] [R].
- Conditions
- Thoracic Surgery, One Lung Ventilation, Left-sided Double Lumen Tube
- Trial name
- NCT04329416
- Testing
- Predicted depth of insertion, Optimized depth of insertion, Adjustment of depth of insertion
- Where
- Saudi Arabia
- Volunteers
- 65 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
One Lung Ventilation
Effectiveness of Lung Sono in One-lung Ventilation
To observe the effectiveness of ultrasound-guided alveolar recruitment in thoracic surgery with one-lung ventilation(OLV).
- Trial name
- NCT03770793
- Testing
- Lung-sono guided
- Where
- South Korea
- Volunteers
- 166 people
- Sponsor
- Seoul National University Hospital
Thoracic Surgery, Cognitive Dysfunction
Cerebral Desaturation and Postoperative Dysfunction After Thoracic Surgery
The purpose of this study prospective observational study is to determine cognitive dysfunction incidence after thoracic surgery.
- Trial name
- NCT03805880
- Testing
- cerebral desaturation monitoring and cognitive examination
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Roma La Sapienza
Lung Cancer
Inflammatory Response After One-lung Ventilation According to Ventilation Methods
Unlike conventional thoracic surgery performed under general anesthesia with tracheal intubation, non-intubated thoracic surgery with sedation and regional anesthesia has been performed recently.
- Trial name
- NCT04007354
- Testing
- Ventilation method
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul St. Mary's Hospital
Mechanical Ventilation Complication, Thoracic Surgery
The Effect of Recruitment Maneuver With Protective Ventilation During Thoracic Surgery
The purpose of this study is to determine if a recruitment maneuver combined with protective ventilatory strategy could reduce the pulmonary and systemic inflammatory responses to one-lung ventilation during thoracic surgery.
- Conditions
- Mechanical Ventilation Complication, Thoracic Surgery, Inflammation
- Trial name
- NCT01630395
- Testing
- protective ventilation, Recruitment maneuver combined with protective ventilation
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Lung Cancer
The Effect of Iloprost on Oxygenation During One-lung Ventilation for Lung Surgery
During one-lung ventilation in patients undergoing thoracic surgery, the persistent flow in the non-ventilated lung increases intrapulmonary shunt and decreases systemic arterial oxygenation.
- Trial name
- NCT03936140
- Testing
- Inhaled iloprost, Distilled water
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Seoul St. Mary's Hospital
Thoracic Anesthesia, One Lung Ventillation (OLV)
Association Between One Lung Ventilation and Myocardial Injury Markers (Troponin T and I) in Thoracic Surgical Procedures (OLVTIS)
This prospective single-group cohort study aims to investigate the association between the One-Lung Ventilation (OLV) technique and myocardial injury, as measured by postoperative Troponin T and Troponin I levels, in patients…
- Trial name
- OLVTIS (NCT07302243)
- Where
- Indonesia
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Universitas Jenderal Soedirman
Postoperative Pain
Comparison of Paravertebral Versus Epidural Block for Post-thoracotomy Pain Control
This is a randomized, assessor-blinded, non-inferiority clinical trial comparing continuous thoracic paravertebral block (BPV) versus continuous thoracic epidural block (BPD) for postoperative pain control in adult patients…
- Trial name
- NCT07763249
- Testing
- Continuous Thoracic Paravertebral Block, Continuous Thoracic Epidural Block
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pneumothorax
Disconnection Technique With a Bronchial Blocker for Improving Lung Deflation
One lung ventilation (OLV) is accomplished with a double lumen tube (DLT) or a bronchial blocker (BB). In this study, the investigators compared the effectiveness of lung collapse using DLT, BB with spontaneous collapse, and BB…
- Trial name
- NCT01846936
- Testing
- DLT with conventional technique, BB with conventional technique, Disconnection technique
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Ajou University School of Medicine
Double-lumen Tube, One-lung Ventilation (OLV)
The Role of Existing Formulas in the Double-lumen Tube in Thoracic Surgery Anesthesia
In most clinical scenarios, left DLT is preferred for one-lung ventilation because of its anatomical ease of placement; these tubes allow separate ventilation of both lungs.
- Conditions
- Double-lumen Tube, One-lung Ventilation (OLV), Thoracic Anesthesia
- Trial name
- NCT07191002
- Testing
- placement depth of the double lumen tube
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Thoracic Surgery
A Clinical Comparison of Three Bronchial Blockers for One-Lung Ventilation in Thoracic Surgery
This is a clinical trial comparing surgical conditions during one-lung ventilation with three different bronchial blockers or with double-lumen endobronchial tubes.
- Trial name
- NCT00188916
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
Endobronchial Intubation, Double Lumen Tube Intubation
Hyperangulated vs Standard Videolaryngoscopy vs Direct Laryngoscopy for Double-Lumen Endobronchial Tube Intubation
This is a prospective, randomized, single-center, three-arm, open-label, low-risk medical device clinical study conducted at the Department of Anesthesiology and Reanimation, Trakya University Medical Faculty.
- Conditions
- Endobronchial Intubation, Double Lumen Tube Intubation, Thoracic Surgery, One Lung Ventillation (OLV)
- Trial name
- NCT07614529
- Testing
- C-MAC Hyperangulated D-Blade Videolaryngoscopy, C-MAC Macintosh Blade Videolaryngoscopy, Direct Macintosh Laryngoscopy
- Volunteers
- 180 people
- Sponsor
- Trakya University
Postoperative Pulmonary Complications, One Lung Ventilation
The Effect of Single Lung Ventilation Duration on Postoperative Pulmonary Complications in Thoracic Surgery
This observational study investigates the relationship between the duration of single-lung ventilation (SLV) and the incidence of postoperative pulmonary complications (PPCs) such as pneumonia, pneumothorax, hemothorax, acute…
- Conditions
- Postoperative Pulmonary Complications, One Lung Ventilation, Ards, Postoperative Pulmonary Atelectasis
- Trial name
- NCT07100860
- Testing
- One-Lung ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
One Lung Ventilation, Intubation Complication
Videolaryngoscopy vs Direct Laryngoscopy for Double Lumen Tube Lumen Tube Placement - A Multicentre Randomized-controlled Trial (VOLCANO Study)
The general aim of the study is to observe whether the use of the Mc Grath™ videolaryngoscope instead of direct laryngoscopy can represent, as in the case of the single-lumen tube, an added value in the placement of the…
- Trial name
- VOLCANO (NCT06466759)
- Testing
- Mc Grath Videolaryngoscope
- Volunteers
- 750 people
- Sponsor
- Luca Brazzi