Clinical trials: Omega-3 Polyunsaturated Fatty Acids
Periodontal Disease
Omega-3 and Aspirin in Periodontal Regeneration
To evaluate the efficacy of systemic administration of omega 3 PUFA plus low dose aspirin as an adjunctive therapy to regenerative modality of grade II furcation defects in periodontitis patients.
- Trial name
- PR (NCT01113528)
- Testing
- Regenerative therapy (omega 3 PUFA plus low dose aspirin), Sugar pill
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- October 6 University
Attention Deficit Hyperactivity Disorder
Omega-3 Supplementation and Attention-deficit-hyperactivity Disorder (ADHD)
It is assumed that only 1/5 of children diagnosed with attention-deficit-hyperactivity disorder (ADHD) are treated. New treatment modalities are urgently needed.
- Trial name
- NCT00874536
- Testing
- omega-3 fatty acid alpha-linolenic acid (ALA)
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Hadassah Medical Organization
Nutritional Status, Serum Biomarkers
A Study of a Dietary Supplement on Serum Biomarkers in Children
This is a pilot clinical study designed to evaluate the effects of a dietary supplement on selected blood-based nutritional biomarkers in healthy children aged 4 to 15 years.
- Trial name
- NCT07385144
- Testing
- Dietary Supplement (Kids Multi & Omegas)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SF Research Institute, Inc.
Vitamin D Deficiency
Clinical Assessment of Adjunctive Omega-3 Versus Vitamin D Daily Supplements on Active Periodontal Therapy With Stage II Grade B Periodontitis Patients
Clinical Assessment of Adjunctive Omega-3 Versus Vitamin D daily Supplements on Active Periodontal Therapy with Stage II Grade B Periodontitis Patients: A Randomized controlled clinical trial.
- Trial name
- NCT06654063
- Testing
- non-surgical periodontal therapy (SRP), non-surgical periodontal therapy (SRP)+ Omega-3, non-surgical periodontal therapy (SRP)+ Vitamin D
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cairo University
Arthritis, Rheumatoid
Omega-3 and Exercise in Rheumatoid Arthritis People
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by autoantibody production and synovial membrane damage. It significantly impairs overall function and quality of life.
- Trial name
- NCT05945693
- Testing
- Omega-3, Aerobic exercise
- Where
- Chile
- Volunteers
- 88 people
- Sponsor
- Instituto de Ciencias de la Salud, Universidad de O'Higgins
Metabolic Syndrome
Metabolic Actions of Omega-3 Fatty Acids
The metabolic syndrome raises the risk of heart disease and is currently at epidemic proportions in the U.S. It consists of 3 of the following components: central obesity, high triglycerides, low HDL, abnormal blood pressure and…
- Trial name
- NCT01896414
- Testing
- EPA (marine fatty acids)
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Stage 0 Breast Carcinoma, Breast Neoplasms
Metformin and Omega-3 Fatty Acids in Woman With a History of Early Stage Breast Cancer
The purpose of this study is to determine whether it is feasible to give a combination of Metformin and omega-3 fatty acids for one year to women with a history of early stage breast cancer.
- Conditions
- Stage 0 Breast Carcinoma, Breast Neoplasms, Stage I Breast Carcinoma, Stage II Breast Carcinoma
- Trial name
- NCT02278965
- Testing
- Metformin, Omega-3 fatty acids
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Katherine D. Crew
Liver Metastasis, Colon Cancer
EPA for Metastasis Trial 2
A significant proportion of patients who undergo liver surgery to remove bowel cancer that has spread to the liver (metastases) develop disease recurrence and die from the disease.
- Trial name
- EMT2 (NCT03428477)
- Testing
- Icosapent Ethyl
- Where
- 13 sites in United Kingdom
- Volunteers
- 418 people
- Sponsor
- Mark A Hull, PhD FRCP
Adolescent Depression
Omega-3 Fatty Acids in Adolescent Depression
Aim. To provide preliminary data about the efficacy of omega-3FA in the treatment of adolescent MDD. To address this aim, a 10-week double blind, placebo-controlled study of omega-3FA, using a flexible dose titration is proposed.
- Trial name
- NCT00312897
- Testing
- Omega-3 Fatty Acids, corn oil
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Healthy
Omega-3 Fatty Acids and Muscle Protein Synthesis
The purpose of this study is to determine whether omega-3 fatty acid supplementation influences muscle protein synthesis rates in young and older adults.
- Trial name
- NCT00794079
- Testing
- omega-3 fatty acids, corn oil
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Treated Hypertension
Pilot Study: Lipoic Acid and Omega-3 Fatty Acids for Alzheimer's Prevention
The primary aim of the pilot study is to provide data that can be used to better determine sample size for the design of a larger clinical trial.
- Trial name
- NCT01780974
- Testing
- Lipoic Acid plus Omega-3 Fatty Acids
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- Oregon Health and Science University
Physical Performance, Cognitive Function
The Impact of Omega-3 Fatty Acid Supplementation on the Composition of Erythrocyte Membranes in Athletes
The aim of this study is to evaluate the effects of omega-3 fatty acid supplementation on the Omega-3 Index, erythrocyte membrane composition, cognitive function, hormonal profile, speed, endurance performance, and hematological…
- Conditions
- Physical Performance, Cognitive Function, Sports Nutrition
- Trial name
- OMEGA-PERFORM (NCT07768423)
- Testing
- EPA + DHA supplements
- Where
- Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Skeletal Muscle Energy Metabolism
The Effect of Omega-3 Fatty Acid Supplementation on Skeletal Muscle Membrane Composition and Cellular Metabolism
The biological membranes that surround a cell and its organelles are vital to the overall function of the cell. Fatty acids are the main structural component of membranes, and the presence of specific fatty acids can alter a…
- Trial name
- NCT01732003
- Testing
- Omega-3 Complete
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Healthy Diet
Nutritional Study on the Beneficial Effects of Canned Fish Consumption on Healthy Adult Population
There is sufficient evidence on the beneficial effects of fish consumption on health, mainly associated with the content of omega-3 polyunsaturated fatty acids (EPA and DHA) present mainly in blue fish.
- Trial name
- TUNACAN (NCT05213273)
- Testing
- nutritional guidelines to promote healthy diet and increase fish intake
- Where
- Spain
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Sara Arranz Martinez
Hypertriglyceridemia
A PK and PD Study of Two Formulations of Omega-3 One Gram Capsules
Comparative bioavailability and pharmacodynamics effects of MAT9001 versus an active omega-3 medication comparator.
- Trial name
- PK/PD (NCT02310022)
- Testing
- Drug Omega 3, Drug Omega-3 Comparator
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Matinas Biopharma, Inc
Multiple Sclerosis, Performance Enhancement
Effects of DHA in Patients With Multiple Sclerosis
This clinical trial will investigate the effects of combining therapeutic exercise with DHA supplementation in 100 patients with multiple sclerosis using a randomized controlled design.
- Conditions
- Multiple Sclerosis, Performance Enhancement, Supplemental Nutrition Assistance Program Education, Strength Outcomes
- Trial name
- DHAME (NCT07346703)
- Testing
- Docosahexaenoic Acid (DHA) Dietary Supplement, Sunflower Oil
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Francisco Javier Martínez Noguera
Dyslipidemias, Fatty Acid; Metabolic Disorder
Short-term Cocoa Supplementation and Elite Soccer Players
The goal of this interventional study was to investigate the impact of daily ingestion of 30g of dark chocolate on omega-3 fatty acid status and gut microbial community in professional soccer players.
- Trial name
- COCOA (NCT06073327)
- Testing
- dark chocolate, White chocolate
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- University of Padova
ASD
Omega-3, Autism Spectrum Disorder (ASD)
This is a 12 week study to investigate the effects of omega-3 polyunsaturated fatty acids (PUFAs) in youth with autism spectrum disorder (ASD).
- Trial name
- OMeASD (NCT07365553)
- Testing
- Omega-3
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- China Medical University Hospital
Inflammation
Maqui Berry Extract and Omega-3 Fatty Acids for Cytokine Reduction
The purpose of this trial is to determine the effect of maqui extract plus omega-3 fatty acids compared to a placebo for reducing inflammatory cytokine levels in older, obese adults.
- Trial name
- NCT04914312
- Testing
- Maqui berry/omeg-3 fatty acids
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Absorption of Omega-3, Omega-3 Supplementation
A Study in Healthy Adults to Compare the Bioavailability of EPA + DHA From Two Microalgal Sources to One Fish Source and Placebo
This is a randomised, double-blind, parallel, placebo-controlled study in healthy adults to compare the absorption of two microalgal formulations, to a fish oil and a placebo.
- Conditions
- Absorption of Omega-3, Omega-3 Supplementation, Healthy Participants
- Trial name
- GOBO 2 (NCT07241377)
- Testing
- life'sTM omega O1035DS nTG, life'sTM omega O3020DS nTG, MEG-3 3323rTG
- Where
- Australia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd