Clinical trials: Omega-3 Polyunsaturated Fatty Acids
Eczema
Omega-3 Monoglyceride Based Topic Products as Skin Prebiotics for Eczema
This exploratory study aims to verify the impact on the severity of eczema as well as the prebiotic potential of a daily application of Omega-3 serum and cream on a skin with eczema.
- Trial name
- NCT06155513
- Testing
- Omega-3 monoglyceride based topical Serum and cream of formulation A (light), Omega-3 monoglyceride based topical Serum and cream of formulation B (rich)
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- SCF Pharma
Absorption of Omega-3, Omega-3 Supplementation
A Study in Healthy Adults to Compare the Bioavailability of EPA + DHA From Two Microalgal Sources to One Fish Source and Placebo
This is a randomised, double-blind, parallel, placebo-controlled study in healthy adults to compare the absorption of two microalgal formulations, to a fish oil and a placebo.
- Conditions
- Absorption of Omega-3, Omega-3 Supplementation, Healthy Participants
- Trial name
- GOBO 2 (NCT07241377)
- Testing
- life'sTM omega O1035DS nTG, life'sTM omega O3020DS nTG, MEG-3 3323rTG
- Where
- Australia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Cardiovascular Disease
Omacor and Placebo in Carotid Plaque Stability
The purpose of this study is to investigate the effect of intake of Omacor (Omega-3-acid ethyl ester 90) 2g/day on specified parameters related to the stability of carotid plaque in patients awaiting endarterectomy.
- Trial name
- NCT00294216
- Testing
- Omega-3-acid ethyl ester 90 (n-3 PUFA)
- Where
- United Kingdom
- Volunteers
- 121 people
- Sponsor
- Pronova BioPharma
IgA Nephropathy
Efficacy and Safety of Omega-3 Fatty Acids(Omacor®) for the Treatment of Immunoglobulin A Nephropathy
The purpose of this study is to compare omega-3 fatty acids with placebo for efficacy in retardation of increase of serum creatinine(SCr) in IgA Nephropathy
- Trial name
- IgAN (NCT00549692)
- Testing
- Omega-3 fatty acid ethylester90
- Where
- 5 sites in South Korea
- Volunteers
- 152 people
- Sponsor
- Kuhnil Pharmaceutical Co., Ltd.
Evaporative Dry Eye Disease
Safety and Efficacy of NovaTears® + Omega-3 (0.2%) Eye Drops on Signs and Symptoms of Dry Eye
This PMCF study is carried out following successful CE marking of NovaTears® + Omega-3 and is intended to generate systematic clinical data on the safety and performance of the device when used in accordance with the intended…
- Trial name
- NCT04521465
- Testing
- NovaTears® + Omega-3 (Perfluorohexyloctane with 0.2% w/w Omega-3 fatty acid ethyl esters)
- Where
- 2 sites in Germany
- Volunteers
- 36 people
- Sponsor
- Novaliq GmbH
Hypertriglyceridemia
Effect of AMR101 (Ethyl Icosapentate) on Triglyceride (Tg) Levels in Patients on Statins With High Tg Levels (≥ 200 and < 500 mg/dL)
The primary objective is to determine the efficacy of AMR101 (ethyl icosapentate) compared to placebo in lowering high fasting triglyceride levels in patients with high risk for cardiovascular disease and fasting triglyceride…
- Trial name
- ANCHOR (NCT01047501)
- Testing
- AMR101 (ethyl icosapentate) - 4 g/day, AMR101 (ethyl icosapentate) - 2 g/day
- Where
- 80 sites in United States
- Volunteers
- 702 people
- Sponsor
- Amarin Pharma Inc.
Patients With Hypertriglyceridemia
The Effect of Phytosterol Esters of Omega-3 (Vayarol) Versus Omega-3 Acids Ethyl Esters in Reducing Triglyceride Levels
The primary objective is to determine the efficacy of phytosterol esters of omega-3 (Vayarol) versus Omega-3 acids ethyl esters in reducing triglyceride levels in hypertriglyceridemia patients with fasting triglyceride levels ≥…
- Trial name
- NCT01712867
- Testing
- Omega-3 acid ethyl esters, Phytosterol esters of omega-3
- Where
- Israel
- Volunteers
- 201 people
- Sponsor
- Enzymotec
Age-Related Cognitive Decline, Age-Related Memory Disorders
Memory Improvement With Docosahexaenoic Acid Study (MIDAS)
The purpose of this study is to investigate the effect of docosahexaenoic acid (DHA, 22:6n-3) in improving cognitive functions in subjects with age-related cognitive decline.
- Trial name
- MIDAS (NCT00278135)
- Where
- 14 sites in United States
- Volunteers
- 485 people
- Sponsor
- dsm-firmenich Switzerland AG
Healthy
A Ph1 Study in Healthy Male Japanese and Caucasian After Single and Multiple Doses of D5884(Omega-3-carboxylic Acids)
The purpose of this study is to assess safety, tolerability and pharmacokinetics of D5884 following administration of single and multiple doses in healthy male Japanese subjects.
- Trial name
- NCT02209766
- Testing
- D5884
- Where
- Japan
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Critical Illness
Parenteral Nutrition With Intravenous and Oral Fish Oil for Intensive Care Patients
The primary objective is to assess the effect of fish oil-enriched enteral and parenteral nutrition on blood oxygenation in critically ill patients.
- Trial name
- NCT01162928
- Testing
- Nutriflex Omega special + Oxepa, Nutriflex Lipid special + Pulmocare
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- B. Braun Melsungen AG
Healthy
Plasma Level of Various Omega-3 Lipids
The primary objective of this study is to evaluate the pharmacokinetic properties of 3 OM3 oils after a single-dose administration in healthy volunteers
- Trial name
- NCT03118999
- Testing
- OM3-FFA, OM3-MAG, OM3-EE
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Skin Health
A Study to Evaluate the Effect of Fish Oil Concentrate on Skin Function
The primary objective of the study is to determine the benefits of the food product EPAX Omega 3-9-11 on skin function. Benefits (if any) will be determined by evaluating biophysical measurements of the face and inner forearm.
- Trial name
- NEMO (NCT07133477)
- Testing
- Omega 3-9-11
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Epax Norway AS
Diabetic Foot Ulcer
Omega3 Wound Fish Skin Graft in the Treatment of DFUs
The purpose of this clinical evaluation is to collect patient outcome data on a commercially available 510K FDA-approved product that is derived from minimal processing of Atlantic cod fish skin: KerecisTM Omega3 Wound.
- Trial name
- NCT04133493
- Testing
- Kerecis Omega3 Wound, Fibracol
- Where
- 5 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kerecis Ltd.
Healthy
Bioavailability of Omega-3 Food Supplements in Healthy Subjects
The study will evaluate the bioavailability of omega-3 based dietary supplements under fasted conditions in healthy adult subjects. Each subject will participate in 5 treatment periods.
- Trial name
- NCT02376621
- Testing
- PronovaPure 150:500 triglycerides, Pronovum PRF-048, Pronovum PRF-037
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pronova BioPharma
Dry Eye Disease
The Influence of PRN Dry Eye Omega-3 Nutritional Regimen on Tear Osmolarity In Cases Of Dry Eye Disease
The investigators hypothesize that oral omega-3-acid triglyceride form will decrease dry-eye related symptoms as well as clinical markers associated with dry eye disease (TearOsmolarity, Schirmer-1 test values, corneal staining…
- Trial name
- NCT02260960
- Testing
- Omega-3 (Triglyceride form)
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Physician Recommended Nutriceuticals
Pharmacokinetic in Normal Population
Effect of Fish Oil Monoglycerides on the Omega-3 Index
The objective of this study is to establish the pharmacokinetic curve for two different doses of MaxSimil at steady-state over a 20-week period, namely two (2) or three (3) tablets per day.
- Trial name
- NCT03735836
- Testing
- MAG-EPA/MAG-DHA omega-3 oils
- Where
- 2 sites in Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Samuel Fortin
Healthy
Toxicity and Safety Evaluation of an Omega-3 Fatty Acid and a Multivitamin and Antioxidant Nutritional Preparation
To evaluate the safety and tolerability of two supplements in healthy subjects taken daily for six months.
- Trial name
- NCT01221714
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- AmeriSciences LP
Enteral Nutrition
The Effect of a New Specific Enteral Formula Compared to a Standard Formula on the Tolerability of a Combined Radio- and Chemotherapy in Cancer Patients
The purpose of the study is to determine the impact of a specific nutrition formula with a high content of eicosapentaenoic acid (EPA) and fat in oncology patients receiving radio-/chemotherapy on body weight, body composition…
- Trial name
- NCT01025167
- Testing
- Supportan(R) (Disease-specific enteral tube feed, food for special medical purposes), Fresubin(R)
- Where
- 10 sites in Germany
- Volunteers
- 111 people
- Sponsor
- Fresenius Kabi
Preterm Infants, Parenteral Nutrition n-3 Fatty Acids
Comparison of Two Different Lipid Emulsions for Parenteral Nutrition in Preterm Infants
The study shall provide evidence for the save and efficient use of a fish oil containing lipid emulsion in parenteral nutrition of preterm infants.Safety will be assessed by monitoring hepatological and hematological laboratory…
- Trial name
- NCT00497289
- Testing
- Lipofundin MCT/LCT 20 %, Lipidem 20%
- Where
- 2 sites in Germany
- Volunteers
- 48 people
- Sponsor
- B. Braun Melsungen AG
Subclinical Hypothyroidism
Dietary Intervention With Únicla Dairy Products (DANTIAN)
Dietary intervention with Únicla dairy products, naturally enriched with selenium and omega-3 fatty acids, may improve thyroid-stimulating hormone (TSH) levels in women with subclinical hypothyroidism
- Trial name
- DANTIAN (NCT05019118)
- Testing
- Experimental milk, Experimental yogur, Experimental fresh cheese
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Cooperativas Lacteas Unidas