Clinical trials: Olfactory Dysfunction
Endonasal Surgery, Endoscopic Sinus Surgery
In Vivo Imaging of the Olfactory Epithelium Using Confocal Laser Endomicroscopy
This research is being done to better characterize the part of the nose that helps people smell. Currently, the only ways to study smell loss mostly rely on how people report it, rather than being able to see the underlying…
- Conditions
- Endonasal Surgery, Endoscopic Sinus Surgery, Olfactory Dysfunction
- Trial name
- NCT07546617
- Testing
- CONVIVO system, Fluorescein injection, USP 10%
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Olfactory Dysfunction, Wellbeing
Impact of Smell Testing on Health Outcomes
Smell dysfunction is frequent yet neglected. The sense of smell plays a crucial role in signaling disease, safety, and overall quality of life.
- Trial name
- NCT07222891
- Testing
- Patient-centered information and education
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Monell Chemical Senses Center
Olfactory Dysfunction, Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Neural Dissimilarity in Patients With Chronic Rhinosinusitis With Nasal Polyps Treated With Biologics
This project will focus on rehabilitation of olfactory dysfunction in patients with chronic rhinosinusitis with polyps given biological treatment based on functional magnetic resonance imaging.
- Conditions
- Olfactory Dysfunction, Chronic Rhinosinusitis With Nasal Polyps (CRSwNP), Functional Magnetic Resonance Imaging (fMRI)
- Trial name
- NCT07819162
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Olfactory Dysfunction
Olfactory Dysfunction in Aging Adults
This prospective longitudinal cohort study will enroll adults aged 50 years and older to characterize olfactory dysfunction in aging.
- Trial name
- NCT07660887
- Testing
- Clinical and Biomarker Assessments
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Healthy Aging, Frailty
Characterisation of Functional and Cognitive Responses Following Olfactory Stimulation and/or Functional Training in Older Adults.
This randomized controlled trial will evaluate the effects of olfactory stimulation and/or multicomponent physical training in adults aged 60 years and older.
- Conditions
- Healthy Aging, Frailty, Cognitive Decline, Olfactory Dysfunction
- Trial name
- INNOLFACT 2 (NCT07623122)
- Testing
- Olfactory stimulation, Multicomponent physical training, Combined olfactory stimulation and multicomponent physical training
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fundacion Miguel Servet