Clinical trials: Older Adults (65 Years and Older), open to volunteers
Older Adults (65 Years and Older), Fitness Testing
Health-related Physical Fitness and Executive Function in Older Adults: A Prospective Study
This study aims to explore the relationship between health-related physical fitness and behavioural and electrophysiological aspects of cool and hot executive function in older adults through a year prospective study design.
- Conditions
- Older Adults (65 Years and Older), Fitness Testing, Executive Function (Cognition), Prospective Study
- Trial name
- NCT07048561
- Testing
- observation alone
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Older Adults (65 Years and Older)
CBT-I in Older African American Adults
Sleep problems, like insomnia, are common in older African Americans. About 25% of older adults in the US have at least 2 symptoms of insomnia, such as having trouble falling asleep, staying asleep, or getting good sleep for a…
- Trial name
- NCT06791356
- Testing
- Cognitive-behavioral therapy for insomnia, Sleep hygiene education
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rutgers, The State University of New Jersey
Frailty, Social Isolation in Older Adults
A Pilot Study to Explore the Feasibility of Navigator and Coach Support for Community Participation by Older People
Frailty is a multidimensional syndrome in which a person accumulates age-related deficits across life domains, increasingly including social components such as social isolation.
- Conditions
- Frailty, Social Isolation in Older Adults, Frailty in Older Adults
- Trial name
- ENGAGE (NCT07836465)
- Testing
- Navigation support, Coaching support
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Bastiaan Van Grootven
Balance Control in Elderly, Falls (Accidents) in Old Age
Turkish Adaptation of the Multidimensional Falls Efficacy Scale in Older Adults
Falls are a major health concern among older adults and can lead to injuries, reduced independence, and a lower quality of life.
- Conditions
- Balance Control in Elderly, Falls (Accidents) in Old Age, Older Adults (65 Years and Older)
- Trial name
- NCT07878832
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Gazi University
Acute Coronary Syndromes (ACS)
Prognostic Value of Functional-Nutritional Status in Older Adults With Acute Coronary Syndrome
This study aims to find out whether reduced everyday functioning before the acute illness and malnutrition help predict health outcomes in adults aged 65 years and older hospitalized with acute coronary syndrome (heart attack or…
- Trial name
- FNS-ACS65 (NCT07898345)
- Testing
- Functional-Nutritional Burden
- Where
- 2 sites in Russia
- Volunteers
- 270 people
- Sponsor
- Samara State Medical University
Multimorbidity, Older Adults (65 Years and Older)
Integrated Care for Older Adults With Major Depression and Physical Multimorbidity - The I-CONNECT
The goal of this clinical trial is to learn if I-CONNECT (Integrated Care for Older Adults with Major Depression and Physical Multimorbidity) can improve the health and well-being of older adults with depression or bipolar…
- Conditions
- Multimorbidity, Older Adults (65 Years and Older), Mood Disorders, Depression - Major Depressive Disorder
- Trial name
- I-CONNECT (NCT07211750)
- Testing
- integrated care intervention tailored to the needs of older adults leaving at home with mood disorders and multimorbidity in Leuven
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- KU Leuven
Awareness During General Anesthesia
Is Density Spectral Array Display Along With Bispectral Index Superior to the Display of Bispectral Index Alone
A study to evaluate the use of density spectral array display in comparison with Bispectral index in a clinical setting.
- Trial name
- DSA-Light (NCT07232160)
- Testing
- Depth of anesthesia monitoring using processed EEG
- Where
- Australia
- Volunteers
- 70 people
- Sponsor
- The University of Queensland
Discharge Planning, Older Adults (65 Years and Older)
Discharge Recommendations for Older Adults Using Physical Outcome Measure
The aim of this study is to explore if the use of Sit to Stand Test and Gait speed Test could assist physiotherapist with discharge planning decisions for older adults who are admitted to an acute hospital.
- Conditions
- Discharge Planning, Older Adults (65 Years and Older), Acute Hospitalization, OUTCOME MEASURES
- Trial name
- DROP (NCT06903832)
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- National University Hospital, Singapore
Hospital Associated Disability, Immobility
Targeting Muscle Strength Loss Due to Hospitalization in Older Adults by Blood-flow Restriction Combined With an Electromyography-driven Serious Game.
This study investigates a new training method designed to help older adults preserve their muscle strength during hospitalization.
- Conditions
- Hospital Associated Disability, Immobility, Older Adults (65 Years and Older)
- Trial name
- GHOSTLY+ (NCT07294131)
- Testing
- Gamified isometric strength training with blood flow restriction, Standard Physiotherapy
- Where
- 3 sites in Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Older Adults (65 Years and Older), Postoperative Care
The Perioperative Pathway for Older Adults
More than 1.5 million people undergo surgery in Sweden each year, and over 770,000 of them are aged 65 years or older. Older adults often have more complex health needs and may require additional support throughout the surgical…
- Conditions
- Older Adults (65 Years and Older), Postoperative Care, Preoperative Care, Intraoperative Care
- Trial name
- POP (NCT07764289)
- Testing
- No intervention
- Volunteers
- 1,000,000 people
- Sponsor
- Örebro University, Sweden
Type 2 Diabetes Mellitus (T2DM), Hyperglycemia
Effects of Short and Long Courses of Intermittent Hypoxic-Hyperoxic Training in Patients With Type 2 Diabetes Including Elderly
This is a single-center randomized controlled trial evaluating the efficacy and safety of short (3 days) versus long (10 days) courses of intermittent hypoxic-hyperoxic training (IHHT) in patients with type 2 diabetes mellitus…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Hyperglycemia, Metabolic Syndrome, Older Adults (65 Years and Older)
- Trial name
- EFIR (NCT07574333)
- Testing
- Intermittent Hypoxic-Hyperoxic Training (3 days), Intermittent Hypoxic-Hyperoxic Training (10 days), Normoxic gas breathing
- Where
- Russia
- Volunteers
- 250 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Loneliness, Older Adults (65 Years and Older)
Using Virtual Reality Travel to Reduce Loneliness in Older Adults
This study aims to investigate whether and how virtual reality travel (VRT) can reduce loneliness among older adults. It will utilize a mixed-methods research design that combines an randomly assigned experiment with follow-up…
- Conditions
- Loneliness, Older Adults (65 Years and Older), Virtual Reality, Leisure Activities
- Trial name
- VRT (NCT07644416)
- Testing
- Virtual Reality Travel, Puzzle-Based Attention Control Activity
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Indiana University
Dehydration, Older Adults (65 Years and Older)
Effect of a Mobile-Based Hydration Tracking Program on Knowledge, Attitudes, and Behaviors in Older Adults
This randomized controlled trial aims to evaluate the impact of a mobile-friendly, web-based hydration tracking application (named "SIVI") on hydration-related knowledge, attitudes, and behaviors in older adults.
- Conditions
- Dehydration, Older Adults (65 Years and Older), Hydration Status, Self-management Behavior
- Trial name
- SIVI (NCT07043933)
- Testing
- Mobile-Compatible Web-Based Hydration Tracking Program
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ezgi Atasoy
Geriatric Assessment, Patients Over 65 Years Old
Transcultural and Psychometric Validation of the Lubben Social Network Scale in Older Adults Living in the French West Indies
Social isolation and loneliness are common among older adults. They are associated with high morbidity and mortality, with an impact comparable to that of other known risk factors such as obesity, a sedentary lifestyle, smoking…
- Trial name
- VALLUB (NCT06909591)
- Testing
- Self-assessment questionnaire
- Where
- Martinique
- Volunteers
- 150 people
- Sponsor
- University Hospital Center of Martinique
Attention Deficit Hyperactivity Disorder
Evaluation of Foquest in Adults 65 Years and Older With ADHD
This study is evaluating the safety and effectiveness of Foquest (multilayer-release methylphenidate), a once-daily extended-release medication for attention-deficit/hyperactivity disorder (ADHD), in adults aged 65 years and…
- Trial name
- NCT07710014
- Testing
- Methylphenidate hydrochloride extended-release capsules
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Dar Clinical Research Inc.
Hypertension Arterial, 65 Years Older
Mitigation of Health Effects in Older Adults With Hypertension by Reducing Exposure to Heat and Air Pollution
The goal of this clinical trial is to assess the effectiveness of an intervention (combination of behavioural recommendations and technical measures) in reducing personal exposure to heat and air pollution and related health…
- Trial name
- ISMED CLIM OH (NCT07606859)
- Testing
- Heat intervention, Heat and air pollution mitigation intervention
- Where
- 2 sites in Cyprus, Spain
- Volunteers
- 102 people
- Sponsor
- University of Cyprus
Older Adults (65 Years and Older), Medical Patients in the Emergency Department
Zinc Supplementation and Infections in Older Medical Patients
The goal of this clinical trial is to learn about the effect of zinc supplementation once daily for 12 months in older acute medical patients.
- Trial name
- ZOOM OUT (NCT07367412)
- Testing
- Zinc (zinc sulphate)
- Where
- 2 sites in Denmark
- Volunteers
- 8,000 people
- Sponsor
- Herlev Hospital
Healthy Volunteer, Older Adults (65-85 Years)
Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
This study plans to learn more about the safety and tolerability of psychedelic administration (psilocybin) in healthy older adults ages 65-85.
- Trial name
- Psil-Pk (NCT07516405)
- Testing
- Psilocybin (Usona Institute)
- Where
- 6 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Older Adults (65 Years and Older)
Technology-based Hand Rehabilitation in Older People
Because hand and cognitive functions decline in the elderly, intervention programs addressing these problems are necessary. In recent years, creating rehabilitation programs using technology has gained popularity.
- Trial name
- NCT07507279
- Testing
- Technological hand rehabilitation exercises, Home exercises, Dual task with technological hand exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Muscle Power, Functional Performance
Acute Power Training Effects in Older Adults
The goal of this clinical trial is to learn how older adults respond to power training when the level of fatigue during exercise is different.
- Conditions
- Muscle Power, Functional Performance, Older Adults (65 Years and Older), Neuromuscular Function
- Trial name
- APTE-OA (NCT07522398)
- Testing
- Power Training at Different Fatigue Levels
- Where
- Belgium
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hasselt University