Clinical trials: Old Age; Debility, open to volunteers
Hospital Associated Disability, Immobility
Targeting Muscle Strength Loss Due to Hospitalization in Older Adults by Blood-flow Restriction Combined With an Electromyography-driven Serious Game.
This study investigates a new training method designed to help older adults preserve their muscle strength during hospitalization.
- Conditions
- Hospital Associated Disability, Immobility, Older Adults (65 Years and Older)
- Trial name
- GHOSTLY+ (NCT07294131)
- Testing
- Gamified isometric strength training with blood flow restriction, Standard Physiotherapy
- Where
- 3 sites in Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Old Age; Debility, Digestive Cancer
Perioperative Multicomponent Rehabilitation and Outcomes in Elderly Patients With Frailty
The study is designed to investigate the effect of a perioperative multicomponent rehabilitation pathway on early and long-term outcomes in elderly patients with frailty recovering from surgery for digestive cancer.
- Conditions
- Old Age; Debility, Digestive Cancer, Surgery, Nutrition Therapy
- Trial name
- NCT04715581
- Testing
- Preoperative nutritional optimization, Perioperative exercise training, Postoperative exercise training
- Where
- China
- Volunteers
- 540 people
- Sponsor
- Peking University First Hospital
Mild Cognitive Impairment, Old Age; Debility
Dual Task Perturbation Training for OAwMCI
Studies have determined that compared to cognitively intact older adults (CIOA), older adults with mild cognitive impairment (OAwMCI) exhibit more pronounced balance and gait impairments which lead to an increased risk of falls…
- Trial name
- NCT04938349
- Testing
- Dual task perturbation training
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Frailty Syndrome, Geriatric Health
Longitudinal Assessment of Lung Function and Respiratory Muscle Strength Following Training of the Inspiratory Muscles in Frail Older Adults (IMT-3)
This study aims to evaluate the effects of an 8-week inspiratory muscle training program on lung function and respiratory muscle strength in frail older adults aged 80 years and above.
- Conditions
- Frailty Syndrome, Geriatric Health, Respiratory Muscle Weakness, Age-Related Frailty
- Trial name
- NCT07556445
- Testing
- Inspiratory Muscle Training
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Muscle Fatigue (C23.888.592.612.612), Muscle Weakness or Atrophy
A Biomechanical Study of Collaborative FES on Lower Limb Motor Function in the Elderly
This study will first conduct a precise assessment of the differences in muscle coordination among the elderly through muscle synergy analysis; then, based on this, it will extract abnormal synergy patterns and muscle activation…
- Trial name
- NCT07245602
- Testing
- Collaborative Functional Electrical Stimulation, Traditional functional electrical stimulation
- Volunteers
- 30 people
- Sponsor
- Chen Xuan
Old Age; Debility
Impact of a Physical Exercise Program in a Rural Area
With this work we want to assess whether there are differences in the amount of physical activity per week, measured by accelerometry in 3 groups of subjects, where one group (G1) has been carrying out a PA program called…
- Trial name
- NCT06842849
- Testing
- Exercise program
- Where
- Spain
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Aging, Muscle Atrophy or Weakness
C-Protein in Fatigue and Aging
This study is investigating changes to the proteins in skeletal muscle that contribute to reduced muscle size and muscle function that occurs with aging.
- Conditions
- Aging, Muscle Atrophy or Weakness, Sarcopenia in Elderly, Sarcopenia
- Trial name
- NCT05926219
- Testing
- Fatiguing Exercise
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Critical Illness, Sarcopenia
Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors
Older ICU survivors with ICU acquired weakness (ICUAW) are malnourished, sarcopenic, and functionally debilitated as a consequence of the high burden of comorbidities common in the elderly.
- Conditions
- Critical Illness, Sarcopenia, ICU Acquired Weakness
- Trial name
- ProMoTE (NCT05326633)
- Testing
- MRP and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES)
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Maryland, Baltimore
Old Age; Debility
Fall Prevention Pathways
Falls are a leading cause of injury and loss of independence in older adults, with evidence supporting exercise-based interventions and remote monitoring as effective strategies for reducing fall risk.
- Trial name
- NCT07824141
- Testing
- The Fall Prevention Pathway (FPP)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Emory University
Resistance Exercise, Muscle Weakness
Effects of Elastic Band Resistance Exercise on Muscle Strength and Depression in Hospitalized Elderly.
With improved a five-day intensive, low-resistance elastic band exercise program to evaluate its effectiveness in improving total muscle mass, upper and lower extremity muscle strength, self-perceived fear of falling, and…
- Conditions
- Resistance Exercise, Muscle Weakness, Functional Decline
- Trial name
- NCT06205147
- Testing
- Elastic Band
- Where
- Taiwan
- Volunteers
- 62 people
- Sponsor
- National Taiwan University
Frailty Syndrome, Geriatric Health
Longitudinal Assessment of Maximal Inspiratory Pressure and Functional Capacity Following Inspiratory Muscle Training in Frail Older Adults (IMT-2)
This study aims to evaluate the effects of an 8-week inspiratory muscle training program on maximal inspiratory pressure and functional capacity in frail older adults aged 80 years and above.
- Conditions
- Frailty Syndrome, Geriatric Health, Respiratory Muscle Weakness, Age-Related Frailty
- Trial name
- NCT07328334
- Testing
- Inspiratory Muscle Training
- Volunteers
- 30 people
- Sponsor
- Universidad Francisco de Vitoria
Age Problem, Old Age; Debility
Swedish Palliative Care Guide (S-PCG) at Nursing Homes
Palliative care aims to improve the quality of life for patients and families who are affected life-threatening, incurable disease. The care should be person-centred, but it is not entirely clear how this is best achieved.
- Conditions
- Age Problem, Old Age; Debility, Dementia
- Trial name
- NCT06431659
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Region Skane
Intensive Care Units (ICUs), Muscle Atrophy or Weakness
Neuromuscular Electrical Stimulation in Critically Ill Patients Aged 80 and Over
The aim of this clinical trial is to evaluate the effectiveness of Medium-Frequency Neuromuscular Electrical Stimulation, in combination with standard physical therapy, compared to standard physical therapy alone, on muscle mass…
- Conditions
- Intensive Care Units (ICUs), Muscle Atrophy or Weakness, Old and Very Old People
- Trial name
- NMES-ICU80 (NCT07127991)
- Testing
- Medium Frequency Neuromuscular Electrical Stimulation (NMES), Standard physical therapy
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Universidad de La Frontera
Old Age; Debility
Combined Effects of NMES and LIRT on Muscle Strength, Girth, and Physical Endurance in the Geriatric Population
This study will employ a randomized controlled trial design with a pre-post design to investigate the combined effects of Neuromuscular Electrical Stimulation (NMES) and Low-Intensity Resistance Training (LIRT) on muscle…
- Trial name
- NCT07646405
- Testing
- Neuromuscular electrical stimulation, lOW intensity resistance training
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University