Clinical trials: Old Adults, open to volunteers
Older Adults (60 - 85 Years Old)
Readiness to Change and the Implementation of Home Modifications for Adults Over 60
This study is focused on home modifications and the changes that older adults may experience while aging. We are conducting this study to better understand how people feel about making changes to their homes or utilizing…
- Trial name
- NCT07383727
- Testing
- Face-to-face educational session, On-line educational session
- Volunteers
- 40 people
- Sponsor
- University of Vermont
Older Adults (60 - 85 Years Old)
Gymnastics and Multicomponent Training Intervention in Community-dwelling Older Adults
Introduction: Extension projects focused on physical activity can offer health practices and promote quality of life for participants of different ages.
- Trial name
- NCT07766954
- Testing
- Multicomponent training intervention Multicomponent training intervention - Protocol includes mobility, resistance exercises for the lower and upper limbs and major muscle groups, and aerobic exercise
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Psychological Distress
Existential Group Treatment for Older Adults (75+) With Psychological Distress in Primary Care
Symptoms of depression and anxiety are common in older adults, and high suicide rates are observed in this age group in Sweden, as in many countries around the globe.
- Trial name
- NCT05503485
- Testing
- Existential group treatment, Supportive telephone calls
- Where
- 7 sites in Sweden
- Volunteers
- 140 people
- Sponsor
- Göteborg University
First Episode Psychosis (FEP), Psychosis
Mobile Application-Based Interventions for Cannabis Use in Young Adults With First Episode Psychosis
Psychotic disorders affect approximately 4% of Canadians and have a significant impact on individuals' well-being, their families and social networks, and healthcare systems.
- Conditions
- First Episode Psychosis (FEP), Psychosis, Schizophreni-form Disorder, Dependence Addictive
- Trial name
- Mobile Health (NCT07811466)
- Testing
- CHAMPS, I Can Change
- Volunteers
- 550 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Postoperative Delirium, Delirium Prevention
Evaluation of a Hospital Program to Prevent Postoperative Delirium in Older Patients
Postoperative delirium is a common complication in older adults undergoing surgery. It is characterized by an acute and fluctuating disturbance of attention, awareness, and thinking.
- Conditions
- Postoperative Delirium, Delirium Prevention, Multicomponent Care Program, Older Adults (60 - 85 Years Old)
- Trial name
- EvaDel (NCT07787832)
- Testing
- Multicomponent delirium prevention program
- Volunteers
- 720 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Older Adults (60 - 85 Years Old)
WhatsApp Radio Taiso Exercise Program for Adults Aged 60+
The aim of this research is to examine the contribution of the Radio Taiso exercise program, offered via the WhatsApp application, to the process of establishing exercise habits in individuals aged 60 and over, and to evaluate…
- Trial name
- NCT07497529
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ondokuz Mayıs University
Healthy Volunteer
A Study to Learn About the Safety of BIIB142 and How it is Processed in the Body of Healthy Adult Participants Aged 18 to 55 Years Old
In this study, researchers will learn more about the safety of BIIB142 and how it is processed in the body. This is the first time that researchers will learn about BIIB142 and how it affects people.
- Trial name
- NCT07133828
- Testing
- BIIB142
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Biogen
Balance Control in Elderly, Falls (Accidents) in Old Age
Turkish Adaptation of the Multidimensional Falls Efficacy Scale in Older Adults
Falls are a major health concern among older adults and can lead to injuries, reduced independence, and a lower quality of life.
- Conditions
- Balance Control in Elderly, Falls (Accidents) in Old Age, Older Adults (65 Years and Older)
- Trial name
- NCT07878832
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Gazi University
Aging, Parkinson's Disease (PD)
Impact of Force Control of Hip Abductor Muscles in Healthy Adults and Individuals With Parkinson's Disease
Both aging and Parkinson's disease (PD) negatively affect postural control and increase the risk of falls, with frontal plane balance being particularly challenging for these populations.
- Trial name
- NCT07568951
- Testing
- Age, Parkinson's disease (PD)
- Where
- 2 sites in Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Cognitive Impairment, Balance Changes
LSVT Big and Dual Task Training in Cognitive Impaired Patients
The goal of this study ifs to determine the comparative effects of Lee Silverman voice treatment Big and dual task training on balance, cognition and functional mobility in older adults with cognitive impairment.
- Conditions
- Cognitive Impairment, Balance Changes, Cognition Disorders in Old Age, Functional Mobility
- Trial name
- NCT06927362
- Testing
- Lee Silverman treatment big, Dual task training
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Colorectal Cancer, Older Adults (60 - 85 Years Old)
Chemo Brain Prehab Project
Colorectal cancer is 37% higher in the North West than the national average and is treated by chemotherapy, including fluorouracil, capecitabine, and oxaliplatin.
- Conditions
- Colorectal Cancer, Older Adults (60 - 85 Years Old), Physically Inactive, Chemotherapy
- Trial name
- CHEMOBRAIN (NCT07341217)
- Testing
- Exercise Prehabilitation, Multivitamins, Standard Care (in control arm)
- Where
- 4 sites in United Kingdom
- Volunteers
- 86 people
- Sponsor
- Dr. Chris Gaffney
Geriatrics, Older Adults (60 - 85 Years Old)
Comorbidity, Cognition, Gait Speed, and Respiratory Muscle Strength in Older Adults
This cross-sectional observational study aims to examine the associations of comorbidity burden and cognitive function with gait speed and respiratory muscle strength in community-dwelling adults aged 60 years and older.
- Conditions
- Geriatrics, Older Adults (60 - 85 Years Old), Aging
- Trial name
- NCT07753421
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Acibadem University
Falls (Accidents) in Old Age, Psychotropic Drugs
Association Between Intake of Psychotropic Medications and Risk of Falls in Older Adults
The aim of the study is to assess the association between intake of psychotropic medications and increased risk of falls in older adults discharged from Ain Shams University Geriatric Hospital as a primary outcome and incident…
- Trial name
- NCT07112573
- Where
- Egypt
- Volunteers
- 398 people
- Sponsor
- Ain Shams University
Parkinson's Disease (PD), Alzheimer's Disease (AD) and Related Disorders
Moving Yourself in Space and Time: MYSTIC
This study is being done to answer the question: Do people with Parkinson's benefit from a new stepping therapy, and how do people with Parkinson's best learn new steps and rhythms set to music? Researchers will also compare…
- Conditions
- Parkinson's Disease (PD), Alzheimer's Disease (AD) and Related Disorders, Older Adults (60 - 85 Years Old)
- Trial name
- MYSTIC (NCT07697664)
- Testing
- Complex Rhythmic Movement Sequences (CRMS) Sessions
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Emory University
Acute Disease, Old Age
Physical Activity During Hospitalization and Hospital-Associated Disability
This study examines physical activity during and after hospitalization in acutely hospitalized older adults and its association with hospital-associated disability (HAD).
- Conditions
- Acute Disease, Old Age, Geriatric, Physical Activity
- Trial name
- NCT07830381
- Testing
- Physical Activity During and After Hospitalization
- Where
- Denmark
- Volunteers
- 170 people
- Sponsor
- Hvidovre University Hospital
Sedation, Analgesia Assessment
Study Comparing Atomizerd Midazolam & Fentanyl and Dexmedomidine for Procedural Sedation in Adult and Pediatric Patient (2 to 60 Years Old)
To evaluate the depth of sedation, as well as onset, and recovery times, satisfaction of sedation , adverse events associated with Atomized Midazolam \& Fentanyl and Dexmedetomidine during procedural sedation in a diverse…
- Trial name
- NCT07166666
- Testing
- atomizer, rescue medication, Midazolam
- Where
- Oman
- Volunteers
- 128 people
- Sponsor
- Oman Medical Speciality Board
Cognitive Decline, Alzheimer Disease
Effects of Real vs. Soundless Acoustic Stimulation During Deep Sleep on Brain Activity, Memory, and Blood Biomarkers in Older Adults (60-85) With Mild Memory Impairment
This study aims to explore a non-invasive way to improve memory and slow cognitive decline in older adults by enhancing sleep quality.
- Conditions
- Cognitive Decline, Alzheimer Disease, Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI)
- Trial name
- NCT06669546
- Testing
- Phase-locked auditory stimulation (PLAS)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University of Bern
Acute Respiratory Failure, Delirium in Old Age
Exploring the Correlations of Lung Ultrasound with Delirium and Outcomes in Acute GEriatrics World: a Multicenter, Prospective, Observational Study from the GRETA Group of the Italian Society of Gerontology and Geriatrics
The purpose of this observational study is to investigate the prognostic relevance of lung ultrasound (LUS) performed on older patients (aged 65 and above) admitted to the hospital with acute respiratory symptoms.
- Conditions
- Acute Respiratory Failure, Delirium in Old Age, Pneumonia, Acute Heart Failure (AHF)
- Trial name
- ECO-AGE (NCT06670118)
- Where
- Italy
- Volunteers
- 480 people
- Sponsor
- University of Milano Bicocca
Insulin Resistance, Inflammation Biomarkers
The Effect of Time Restricted Eating on Glycemic and Proinflammatory Biomarkers Among Prediabetic Obese Jordanian Adults Aged 18-40 Years Old
Obesity, a global epidemic, significantly contributes to prediabetes, cardiovascular diseases, and other chronic diseases due to its pro-inflammatory nature.
- Conditions
- Insulin Resistance, Inflammation Biomarkers, Time Restricted Eating, Caloric Restriction
- Trial name
- NCT06911918
- Testing
- time restricted eating with caloric restriction, time restricted eating without caloric restriction, Caloric restriction without Time restricted eating
- Where
- Jordan
- Volunteers
- 120 people
- Sponsor
- University of Jordan
Stress
Effect of Daily Humiome® Post LB Intake on Wellbeing in Older Individuals With Moderate Stress Levels
The placebo-controlled, double blind parallel intervention trial "PostWelLB" aims to test whether 3 months of daily supplementation with the postbiotic product "Humiome® Post LB" (HPLB; 340 mg / day) can reduce self-reported…
- Trial name
- PostWelLB (NCT07471659)
- Testing
- Humiome Post LB, Microcrystalline Cellulose
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG