Clinical trials: Ocular Disorder
Dry Eye, Meibomian Gland Dysfunction (Disorder)
Effect of Low-Level Light Therapy on Ocular Surface Parameters in Patients Undergoing Cataract Surgery
This randomized, controlled clinical trial investigates the perioperative use of low-level light therapy (LLLT) to prevent or reduce signs and symptoms of dry eye disease (DED) in patients undergoing cataract surgery.
- Conditions
- Dry Eye, Meibomian Gland Dysfunction (Disorder), Ocular Surface Disease
- Trial name
- LLLT-Cataract (NCT07067294)
- Testing
- Low-Level Light Therapy
- Where
- Romania
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
MTBI - Mild Traumatic Brain Injury
Validation of Clinical Outcome Measures Specific to mTBI-Related Oculomotor Disorders
The specific aim of this project is to validate clinical tests to be used as outcome measures in studies of mTBI-related vision problems.
- Trial name
- NCT07282691
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Salus University
Vestibulo-Ocular Reflex (VOR) Dysfunction, Vestibular Function Tests
Smartphone-based Utility of the Vestibulo-ocular Reflex
The goal of this observational study is to evaluate whether a novel smartphone-based (mHealth) application can accurately assess gaze stability and vestibulo-ocular reflex (VOR) function in adults with vestibular dysfunction.
- Conditions
- Vestibulo-Ocular Reflex (VOR) Dysfunction, Vestibular Function Tests, Vestibular Function Disorder, mHealth Application
- Trial name
- NCT06856746
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Dry Eye, Meibomian Gland Dysfunction (Disorder)
Effect of Low-Level Light Therapy on Ocular Surface Parameters in Patients Undergoing Femto-Lasik Surgery
This study evaluates the role of perioperative low-level light therapy (LLLT) in reducing dry eye disease (DED) symptoms after femtosecond laser-assisted in situ keratomileusis (Femto-LASIK).
- Conditions
- Dry Eye, Meibomian Gland Dysfunction (Disorder), Ocular Surface Disease
- Trial name
- LLLT-Lasik (NCT07181668)
- Testing
- Low-Level Light Therapy
- Where
- Romania
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Dry Eye, Neuropathic Eye Pain
Azithromycin for Meibomian Gland Disease
This study aims to elucidate the effectiveness of oral azithromycin in treating symptomatic dry eye syndrome secondary to Meibomian gland dysfunction.
- Conditions
- Dry Eye, Neuropathic Eye Pain, Ocular Microbiome, Depression, Anxiety
- Trial name
- NCT03953118
- Testing
- Azithromycin Oral Product
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of California, San Francisco
Convergence Insufficiency
Effect of Oculomotor Therapy in Individuals With Convergence Insufficiency
The aim of this study is to investigate the effect of oculomotor therapy in individuals with ocular convergence insufficiency.
- Trial name
- NCT07036263
- Testing
- Oculomotor therapy, No Treatment Added
- Volunteers
- 70 people
- Sponsor
- University of Nove de Julho
Multiple Sclerosis, Clinically Isolated Syndrome
Visual Processing Speed and Objective Analysis of Ocular Movements in Multiple Sclerosis
This project aims to analyze ocular motility problems, visual processing speed and microperimetry, and their relationship with consolidated retinal structural biomarkers (optical coherence tomography, OCT) in patients with…
- Conditions
- Multiple Sclerosis, Clinically Isolated Syndrome, Relapsing Remitting Multiple Sclerosis, Progressive Multiple Sclerosis
- Trial name
- NCT05706220
- Testing
- Eye tracking, Microperimetry, Optical coherence tomography (OCT)
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA
Glaucoma Associated With Other Ocular Disorders
oCular Examination at Cell RESolution With Optical TransmissionTomography
Understanding the pathogenesis of eye diseases has benefited greatly from recent advances in ophthalmic imaging. However, current clinical imaging systems, such as optical coherence tomography (OCT), are limited in terms of…
- Trial name
- CERES-OTT (NCT06976034)
- Testing
- Optical Transmission Tomography (OTT), Optical Coherence Tomography (OCT), Specular Microscopy (SM)
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Convergence Insufficiency
Efficacy Of Pencil Pushup Exercise Vs Base Out Exercising Prism's In Patient With Convergence Insufficiency
Convergence insufficiency (CI) is a prevalent binocular vision disorder that leads to symptoms such as eye strain, headaches, and blurred vision during near work.
- Trial name
- NCT06913829
- Testing
- base-out exercising prisms, pencil pushup exercises
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Superior University
Convergence Insufficiency
Natural History of MTBI-related Convergence Insufficiency & Effectiveness of Vision Therapy for MTBI-related CI
The design of this project is a pilot study, a type of feasibility study conducted in preparation for subsequent RCTs that will assess the effectiveness of office-based vergence/accommodative therapy with movement (OBVAM) for…
- Trial name
- TBEye (NCT06848673)
- Testing
- Office-Based Vergence/Accommodative Therapy with Movement (OBVAM)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Salus University
Amblyopia, Ocular Motility Disorders
A New Approach to Vision Therapy Based on Naturalistic 3-D Computer Gaming
The research team will execute two concurrent studies within a common framework. The first will compare iCare to standard of care occlusion therapy (patching) for amblyopia in patients ages 4 to 18 (inclusive).
- Trial name
- ICARE (NCT03066063)
- Testing
- iCare, Amblyopia standard of Care, CI standard of Care
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Barron Associates, Inc.
Convergence Insufficiency
The Effectiveness of Visual Training in Convergence Insufficiency Patients
Convergence insufficiency (CI) is one of the most common binocular vision disorders. The prevalence of CI ranges from 3% to 6% in school-aged children.
- Trial name
- NCT05603962
- Testing
- Visual training
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- National Taiwan University Hospital
Convergence Insufficiency
Non-invasive Brain Stimulation for Treating Symptomatic Convergence Insufficiency
The goal of this randomized controlled trial is to test the effectiveness of non-invasive brain stimulation in treating adults with symptomatic convergence insufficiency compared to vergence/accommodative therapy.
- Trial name
- NIBSCI (NCT05877560)
- Testing
- Anodal-Transcranial Direct Current Stimulation, Office-Based Vergence/Accommodative Therapy
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Glaucoma, Macular Degeneration
BCI and Evaluation of Visual and Task Performance in Subjects With Eye Diseases
The purpose of this research study is to better understand the impact of visual impairment caused by different eye diseases on the ability to perform daily activities and compare it to that in patients without eye diseases.
- Conditions
- Glaucoma, Macular Degeneration, Glaucoma Suspect, Optic Neuropathy
- Trial name
- NCT03318549
- Testing
- Visual Performance tests, Brain-computer interface
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Miami
Multiple Sclerosis, Internuclear Ophthalmoplegia
Studying Eye Movement Deficits and Cognitive Impairment in Patients with Multiple Sclerosis Using Infrared Eye Tracking and Cognitive Tests
The goal of this observational study is to study the relationship between cognitive problems and problems in eye movements in Multiple Sclerosis (MS).
- Trial name
- VisuMS (NCT06629155)
- Testing
- Infrared oculography
- Volunteers
- 50 people
- Sponsor
- Universitair Ziekenhuis Brussel
Myasthaenia Gravis, Myasthenia
Myasthenia Gravis Foundation of America Global MG Patient Registry
The goal of this observational study is to learn about the experiences of people living with Myasthenia Gravis (MG) in the United States.
- Conditions
- Myasthaenia Gravis, Myasthenia, Myasthenia Gravis Associated with Thymoma, Myasthenia Gravis Crisis
- Trial name
- MGFAPR (NCT06617741)
- Where
- United States
- Volunteers
- 3,800 people
- Sponsor
- Myasthenia Gravis Foundation of America
Myasthenia Gravis, Autoimmune Diseases of the Nervous System
Predictors and Prognostic Factors of Myasthenia Gravis Outcome
This study aims to characterize the clinical features, frequency of different subgroups of MG, and identify predictors of treatment responsiveness among different subgroups of MG.
- Conditions
- Myasthenia Gravis, Autoimmune Diseases of the Nervous System, Neuromuscular Junction Diseases, Thymoma
- Trial name
- NCT05214612
- Testing
- Drug treatment of myasthenia gravis and treatment of crisis
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Ophthalmological Disorder
Effect of Binocular Treatment Using a Dichoptic Reading Application in Children With Convergence Insufficiency.
Convergence insufficiency is a common disorder of binocular vision that can appear as early as childhood after visual effort, and is often associated with a variety of symptoms such as eyestrain, headaches, blurred vision and…
- Trial name
- ALEDICE (NCT06465615)
- Testing
- Self-education with dichoptic reading on tablet, Conventional orthoptic rehabilitation
- Volunteers
- 26 people
- Sponsor
- University Hospital, Montpellier
Convergence Insufficiency
Effectiveness of Virtual Reality Vision Therapy - VERVE
The purpose of this research study is to see how well the treatment of a participant's eye coordination and/or focusing problems improves eye muscle responses and symptoms of eyestrain.
- Trial name
- VRVT - VERVE (NCT04691427)
- Testing
- Virtual Eye Rotation Vision Exercises (VERVE)
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- OculoMotor Technologies
Temporomandibular Disorder, Temporomandibular Joint Disorders
Effect of Exercises on Convergence Insufficiency in Individuals With Temporomandibular Disorders
Temporomandibular Disorder is a disorder that involves the muscles of mastication, the temporomandibular joint (TMJ), and associated structures.
- Conditions
- Temporomandibular Disorder, Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome, Convergence Insufficiency
- Trial name
- NCT05761106
- Testing
- Oculomotor Therapy, Therapy for Temporomandibular Disorder
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- University of Nove de Julho