Clinical trials: Occupational Exposure
Human Immunodeficiency Virus
The Tolerability of, and Adherence to, Dolutegravir With Co-formulated Tenofovir-emtricitabine for HIV Non-occupational Post-exposure Prophylaxis
This study aims to describe the proportion of participants with non-occupational post-exposure prophylaxis (NPEP) failure, defined as NPEP non-completion (including loss to follow-up) at week 4 or primary HIV infection at week 4…
- Trial name
- dPEP (NCT02211690)
- Testing
- dolutegravir 50 mg (one tablet daily), emtricitabine-tenofovir 300/200 mg (one tablet daily)
- Where
- 5 sites in Australia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Andrew Carr
Sleep Initiation and Maintenance Disorders, Circadian Rhythm Sleep Disorders
Light Exposure to Treat Sleep Disruption in Older People
The purpose of this study is to test whether shifts in the timing of the biological clock to a later hour (phase delay shifts of the human circadian system) can be produced in response to four successive evenings of light…
- Conditions
- Sleep Initiation and Maintenance Disorders, Circadian Rhythm Sleep Disorders, Hypersomnia
- Trial name
- NCT00427323
- Testing
- light exposure
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Chronic Obstructive Pulmonary Disease
Molecular, Cytological Features and Genetic Susceptibility of COPD Attributable to Different Environmental Exposures
The objective of this study is to investigate molecular, cytological and genetic features of occupational chronic obstructive pulmonary disease (COPD) in conditions of different occupational exposures.
- Trial name
- NCT02220387
- Testing
- exposure to respirable silica dust, exposure to polycyclic aromatic hydrocarbons exhaust
- Where
- Russia
- Volunteers
- 352 people
- Sponsor
- Novosibirsk City Hospital #2
Exposure to Environmental Pollution, Non-occupational
The Interaction of Social Factors With Air Pollution
Purpose: The purpose of this protocol is to understand how social factors such as psychosocial stress may modify how people respond to air pollution.
- Trial name
- SOZIAL (NCT02206750)
- Testing
- Clean Air, Ozone
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Ebola Vaccine
Immunity Induced by VSV-EBOV and Assessment of a Booster Dose in Individuals at Potential Occupational Risk for Exposure
This study is a multi-center, open label, randomized phase 3b trial to assess the durability of Immunity induced by the Ebolavirus Vaccine VSV-EBOV ( with or without booster vaccination) in individuals at potential occupational…
- Trial name
- PREPARE (NCT05959421)
- Testing
- ERVEBO® (rVSV∆G-ZEBOV-GP)
- Where
- 2 sites in Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Silicosis
Reducing Silica Exposure Among Brick Kiln Workers in Nepal
Inhaling respirable silica increases the risk for silicosis, an incurable and debilitating lung disease. In South Asia, one high-risk industry is brick manufacturing, where more than 4 million manual laborers mold bricks by hand.
- Trial name
- NCT06090370
- Testing
- N95 Respirator, Protective Eyewear, Baseline Survey
- Where
- 3 sites in United States, Nepal
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Skin Cancer, Heat Tolerance
Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals
The escalating environmental heat-stress associated with global warming is a societal challenge with large and potential harmful consequences for humans.
- Conditions
- Skin Cancer, Heat Tolerance, Heat-related Illness, Hyperthermia
- Trial name
- ICARUS (NCT07510061)
- Testing
- Controlled Heat and Ultraviolet Radiation Exposure Protocol
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Body Temperature Changes, Heat Stress
Working in the Heat at Simulated Altitude: Effects of Normobaric Hypoxia on Physiological Strain
Extreme heat events are becoming more frequent, intense, and prolonged, increasing the risk of heat-related illness among workers performing physically demanding work in hot environments.
- Conditions
- Body Temperature Changes, Heat Stress, Heat Exposure, Heat Fatigue
- Trial name
- NCT07664462
- Testing
- Simulated Occupational heat exposure under normoxic conditions, Simulated Occupational heat exposure under hypoxic conditions
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Ottawa
Hiv
Evaluation of (Doravirine / Lamivudine / Tenofovir Disoproxil Fumarate) (Delstrigo®) as a New Strategy for Non-occupational Post Exposure Prophylaxis, a Prospective Open Label Study
Subjects who go to emergency room for possible contact to HIV transmission receive Delstrigo as post exposition prophylaxis.
- Trial name
- DORAVIPEP (NCT04233372)
- Testing
- Delstrigo
- Where
- 2 sites in France, Spain
- Volunteers
- 399 people
- Sponsor
- Hospital Clinic of Barcelona
Lead Poisoning
Exposure, Dose, Body Burden and Health Effects of Lead
This is a study of the effects that lead has on the health of the central nervous system (for example, memory), peripheral nervous system (for example, sensation and strength in the hands and fingers), kidneys, blood pressure…
- Trial name
- NCT00013819
- Volunteers
- 944 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Gingival Pigmentation, Occupational Heat Exposure
Reducing Gingival Pigmentation Through Workplace Mitigation in Restaurant Oven Workers
Restaurant workers who spend much of their workday near ovens, grills, or other cooking equipment may breathe smoke and experience high heat.
- Conditions
- Gingival Pigmentation, Occupational Heat Exposure, Occupational Air Pollution Exposure
- Trial name
- NCT07805824
- Testing
- Workplace Heat and Air Pollution Mitigation Package, Delayed Workplace Heat and Air Pollution Mitigation Package
- Where
- Iraq
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Salah M. Ibrahim
Biological Specimens
Rapid Acquisition of Pre- and Post-Incident Disaster Data
Background: Disasters like earthquakes, floods, and oil spills can give people health problems. Workers who respond to a disaster (like police and firefighters) are directly exposed to contaminants during the emergency response.
- Trial name
- NCT02473770
- Where
- United States
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Occupational Exposure
Knowledge- Attitude- Practice (KAP) of Post Exposure Prophylaxis for Fifth Year Dental Students of a Private Egyptian University
considering the increase number of occupational injuries, The aim of this study is to assess the current level of knowledge, attitude and practice of fifth year dental students as regards post exposure prophylaxis.
- Trial name
- Cross-section (NCT03893383)
- Volunteers
- 420 people
- Sponsor
- Cairo University
Occupational Exposure to Chemicals
Chemical and Microbiological Exposure of Women on Dairy Cattle Farms
Although professionals working on dairy cattle farms come into contact with a wide range of chemicals and microbiological agents, little is known about this possible exposure, which occurs a priori via inhalation and skin…
- Trial name
- DAISY-Expo (NCT06709989)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Occupational Exposure to Radiation
Radioprotective Light-weight Caps in the Interventional Cardiology Setting
The primary objective of the present trial is to compare the radiation attenuation provided by XPF caps (0.5mm lead-equivalent and 0.3mm lead-equivalent) to the standard protection (fabric cap, basically no protection) as…
- Trial name
- PROTECT (NCT01620658)
- Testing
- 0.5mm XPF cap, 0.3mm XPF cap, Standard cap
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Baptist Health South Florida
Work Ability, Occupational Health
The Esbjerg Cohort - A Cross-sectional Study About Work Ability and Musculoskeletal Pain in 55 to 70 Years Old Workers
The overall aim of this study is to investigate how work with physical demands affects the physical capacity, work ability, labor market affiliation, pain and self-reported health in the oldest group of workers.
- Conditions
- Work Ability, Occupational Health, Physical Capacity, Occupational Exposure
- Trial name
- NCT05811767
- Testing
- Health Examination
- Where
- Denmark
- Volunteers
- 331 people, healthy volunteers welcome
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Parkinson Disease, Secondary
Study on the Relationship Between Environmental and Occupational Exposure to Metals and Parkinson's Disease
The Department of Experimental Medicine - Section of Hygiene, Occupational Medicine, Forensic Medicine of the Second University of Naples, the Section of Neurology of the Second University of Naples and the Mediterranean…
- Trial name
- NCT02588924
- Testing
- Second University of Naples, Neuromed IRCCS
- Where
- 2 sites in Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Viral Hepatitis C
Hepatitis C Virus Post-Exposure Prophylaxis for Health Care Workers
To assess the safety and tolerability of the use of telaprevir in the setting of post-exposure prophylaxis among HCW exposed to HCV genotype 1 or genotype 2.
- Trial name
- NCT01766115
- Testing
- Telaprevir
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Interstitial Lung Diseases (ILD), Pulmonary Emphysema
Clinical Utility of LIBS Multi-Element Imaging and the IFF Algorithm in Chronic Lung Diseases
PNEUMO-LIBS is a multicenter, non-interventional observational study designed to evaluate whether multi-element tissue imaging by Laser-Induced Breakdown Spectroscopy (LIBS), combined with an artificial intelligence-based…
- Conditions
- Interstitial Lung Diseases (ILD), Pulmonary Emphysema, Chronic Lung Diseases, Occupational Lung Diseases
- Trial name
- PNEUMO-LIBS (NCT07597187)
- Where
- 3 sites in France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Grenoble
Screen Time Exposure
The Effects Of Occupation-Based Self-Regulation Program On Sensory Processing, Executive Functions and Occupational Performance In Preschool Children With Screen Addiction
The purpose of this interventional study was to measure the effectiveness of a self-regulation program for screen addiction in preschool children aged 4-5 years.
- Trial name
- NCT07004036
- Testing
- Occupation-based Self-Regulation Intervention Program, Family Awareness Training
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi