Clinical trials: Obstetric Pain
Pain, Obstetric
Efficacy of Extended-Release Liposomal Bupivacaine for Post-Partum Pain Management Following Obstetrical Laceration
We propose a prospective, randomized, single blinded trial with subjects recruited from the WRNMMC Labor and Delivery Unit to study post-partum efficacy of Exparel® for pain control in patients undergoing a vaginal delivery who…
- Trial name
- NCT03152877
- Testing
- Bupivacaine Liposome Injectable Product, 0.25% plain bupivacaine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Obstetric Pain, Other Complications of Obstetric Anesthesia - Delivered
Epidural Dexamethasone for Labor Analgesia: the Effects on Ropivacaine Consumption and Labour Outcome
To assess the efficacy of epidural dexamethasone administration, compared to placebo, in reducing local anesthetics consumption during labor epidural analgesia in parturient women
- Trial name
- DEXAPER (NCT02857465)
- Testing
- Dexamethasone, Ropivacaine, Sufentanil
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Obstetric Pain
Ropivacaine Continuous Wound Infusion Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Delivery
Cesarean delivery is one of the most common surgical procedures, performed at an increasingly high rate. It is associated with intense postoperative pain that may hamper the rehabilitation process and interfere with patient…
- Trial name
- NCT03502642
- Testing
- wound infusion (Dosi-Pain® Kit, LEVENTON SAU, Spain), Spinal Anesthesia, intrathecal morphine
- Where
- Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Obstetric Pain
Bupivacaine Verus Pethidine for Post Cesarean Section Pain Relief
The aim of this study is to compare between the effect of wound infiltration with bupivacaine or pethidine for post cesarean section pain relief.
- Trial name
- NCT03652116
- Testing
- Wound infiltration by Bupivacaine, Wound infiltration by Pethidine
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Ain Shams University
Obstetric Pain
The Effect of the Transversus Abdominis Plane Block to Postoperative Analgesia for Cesarean Section
The transversus abdominis plane block (TAP block) has effect to postoperative analgesia for cesarean section with spinal anesthesia but it was limited for cesarean section with general anesthesia.
- Trial name
- TAP (NCT03634111)
- Testing
- TAP block, Morphine, Ropivacaine
- Where
- Vietnam
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gia Dinh People Hospital
Labor Pain, Obstetric Pain
Color Doppler Ultrasound to Locate Needle in Labor Epidural
Color Flow Doppler (CFD) utilizes Doppler information obtained from signals sent to and received from a transducer. This information is color-encoded and then displayed as color on an overlay of the two-dimensional image.
- Trial name
- NCT03596333
- Testing
- Retrospective chart review
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Augusta University
Obstetric Pain
Effect of Preemptive Epidural Analgesia in Labor on Cytokine Production
During labor there is an increased production of inflammatory mediators called cytokines. Higher concentration of certain cytokines has been linked to adverse neonatal and maternal outcomes.
- Trial name
- NCT00361712
- Testing
- Preemptive epidural analgesia, Standard of care
- Where
- Israel
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Labor Complication, Labor Pain
Wide Use of Paperless Partograph in Evaluation of Labour
Paperless partograph wide using in labour room as simple tool in evaluation of labour
- Trial name
- labourRecord (NCT03276117)
- Where
- 6 sites in Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Preterm Labor, Preterm Contractions
Screening To Obviate Preterm Birth
Our objective is to investigate the predictive value of a panel of biomarkers associated with two biologically plausible pathways of preterm birth: membrane breakdown and cervical remodeling.
- Conditions
- Preterm Labor, Preterm Contractions, Abdominal Cramping, Back Pain
- Trial name
- STOP (NCT01868308)
- Where
- United States
- Volunteers
- 589 people
- Sponsor
- University of Pennsylvania
Obstetric Pain
Analgesic Efficacy of Two Concentrations of Bupivacaine in Women in Labor
Abstract. Epidural analgesia is the most safe and effective for the treatment of pain of childbirth method. Epidural Bupivacaine provided excellent analgesia for labor and remains the most widely used local anesthetic in…
- Trial name
- EBWL (NCT02244086)
- Testing
- bupivacaine
- Where
- Mexico
- Volunteers
- 114 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Labor Pain, Obstetric Pain
ANSiStim Study for Active Labor Pain
The specific aim of the study is to do comparison between ANSiStim and Placebo for pain relief in labor. During the treatment, pain relief will be assesed with ANSiStim in active labor through continues checking of VAS SCORE.
- Trial name
- ANSS-ALP (NCT02427139)
- Testing
- ANSiStim
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- DyAnsys, Inc.
Pregnancy, Obstetric Labor
Effects of Digital Vaginal Examination During Labor on Pain and Anxiety Levels
Digital vaginal examination is the most common method for assessing progress of labor and delivery. Considering it is the most common intervention women receive during course of labor, evidence for psychological effects of…
- Trial name
- NCT02599610
- Testing
- Digital vaginal examination, Transperineal ultrasound examination
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ankara University
Labor, Obstetric, Pain
Estimation of Pain During Epidural Analgesia During Labor
Epidural regional anesthesia is a technique to eliminate or lessen pain during obstetric labor and childbirth. It consists in establishing a catheter into the epidural space and to block the transmission of pain sensations by…
- Trial name
- PERIDANS (NCT02551354)
- Testing
- Portable video pupillometer
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pain, Postoperative, Gynecologic Surgical Procedures
Comparison of Subcuticular Suture Versus Surgical Staples for Closure of Pfannenstiel Skin Incisions
This study compares methods of closure for Pfannenstiel incisions commonly used during gynecological and obstetrical surgery. Patients are assigned to closure by either surgical staples or a buried suture.
- Conditions
- Pain, Postoperative, Gynecologic Surgical Procedures, Obstetric Surgical Procedures
- Trial name
- NCT00186732
- Testing
- Subcuticular Suture, Surgical Staples
- Where
- Canada
- Volunteers
- 288 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Pain, Labor Complications
Dilute Versus Concentrated Epidural Bupivacaine in Labor
This study studies labor epidural analgesia and compares dilute (0.0625%) with concentrated (0.25%) bupivacaine. We hypothesize that patients randomize to receive the concentrated drug will require more drug, will have a more…
- Trial name
- NCT00197327
- Testing
- Epidural bupivacaine (0.25% versus 0.0625%)
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Hadassah Medical Organization