Clinical trials: Obstetric Anesthesia
Placenta Accreta, ESPB
Evaluating the Intraoperative Analgesic Effect of Ultrasound Guided Erector Spinae Plane Block in Parturient Undergoing Elective Cesarean Section for Placenta Accreta Under General Anesthesia.
Due to the significant risk of massive bleeding complicated by profound hypotension and coagulopathy and a high likelihood of hysterectomy during caesarean delivery, general anesthesia is generally regarded as the anesthetic of…
- Conditions
- Placenta Accreta, ESPB, C-section, General Anesthesia
- Trial name
- NCT07748741
- Testing
- ultra sound guided Erector spinae plane block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Kasr El Aini Hospital
Cesarean Section Complications, Postpartum Hemorrhage
Perioperative Outcomes of Postpartum Hemorrhage in Patients Undergoing Cesarean Delivery
Postpartum haemorrhage is the common cause of maternal death worldwide. The primary purpose of this study is to identify the maternal outcomes after PPH.
- Conditions
- Cesarean Section Complications, Postpartum Hemorrhage, Anesthesia Complication, Blood Transfusion Complication
- Trial name
- NCT04833556
- Where
- Thailand
- Volunteers
- 649 people
- Sponsor
- Mahidol University
Covid19, Obstetric Anesthesia
Obstetric Anesthesia Experiences in COVID-19 Positive Patients
At the end of 2019, a new coronavirus named COVID-19 (SARS-CoV-2), one of the lower respiratory tract samples was detected in China.
- Trial name
- NCT04691934
- Testing
- Anesthesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Turkiye Yuksek Ihtisas Education and Research Hospital
Blood Patch, Post-Dural Puncture Headache
Factors Associated With the Onset of Chronic Headaches in Patients Who Received a Blood Patch in Post Partum
The purpose of this study is to identify possible links between conditions for carrying out a blood patch (BP) to treat accidental post dural puncture acute headache (PDPH) in the early post partum period and occurrence of…
- Trial name
- CHROBLOOD (NCT05888324)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 98 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anesthesia; Sexual, Analgesia
The Effect of Peripheral Nerve Blocks on Postoperative Analgesia in Elective Cesarean Section
The goal of this prospective randomized study was to compare the efficacy of transversus abdominis plane block and transversalis fascia plane block for postoperative analgesia in patients undergoing elective cesarean section…
- Trial name
- NCT05758233
- Testing
- Patients undergoing transversalis fascia plane block, Patients undergoing transversus abdominis plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Hypotension, Obstetric Anesthesia Problems
Prevention of Maternal Hypotension During Cesarean Section With Norepinephrine Infusion.
This will be a randomized study aiming at investigating the combination of a norepinephrine infusion and colloid preloading versus the combination of a norepinephrine infusion and crystalloid co-loading for the prevention of…
- Conditions
- Hypotension, Obstetric Anesthesia Problems, Cesarean Section Complications, Hypotensive
- Trial name
- annie-manos (NCT04406051)
- Testing
- norepinephrine infusion and colloid preloading (NOR-COL), norepinephrine infusion and crystalloid co-loading (NOR-CRYST)
- Where
- 2 sites in Greece
- Volunteers
- 100 people
- Sponsor
- Aretaieion University Hospital
Obesity, Morbid, Obstetric Anesthesia Problems
Intravenous Access Using Infrared Laser
Peripheral venous access is a prerequisite for anesthesiological for surgical patients.It is often difficult to establish and potentially painful in obese patients (Body mass Index > 35).
- Trial name
- AccuV (NCT03555864)
- Testing
- infrared transluminescent device
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Postoperative Pain Management, Obstetric Anesthesia
Effect of Bilateral Ultrasound-Guided TAP Block on Quality of Recovery in Cesarean Delivery Patients Receiving Intrathecal Morphine
This prospective, assessor-blinded observational cohort study will investigate the effect of adding bilateral ultrasound-guided transversus abdominis plane (TAP) block to standard intrathecal morphine (ITM) analgesia on the…
- Conditions
- Postoperative Pain Management, Obstetric Anesthesia, Recovery From Anesthesia
- Trial name
- QoR-TAP (NCT07145619)
- Testing
- Spinal Anesthesia with Intrathecal Morphine Only, Spinal Anesthesia with Intrathecal Morphine plus Bilateral TAP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- MEHMET GÖKHAN TAFLAN
Breech Presentation
Impact of Analgesia on Success of External Version: Comparison of Spinal Anesthesia Versus Sedation
At the time of birth, nearly 5% of children are in breech presentation. This type of presentation requires a medical environment and leads to more frequent use of Caesarean sections.
- Trial name
- RaVem (NCT02801201)
- Testing
- Midazolam, Bupivacaine
- Where
- France
- Volunteers
- 186 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Obstetric Pain, Anesthesia, Local
Electrical Epidural Stimulation Test for Detecting Epidural Catheter Reactivation in Obstetric Population
Following labor, epidural or combined spinal-epidural (CSE) catheters are kept in place and deactivated. However, many women opt for procedures such as tubal ligation, which may require epidural anesthesia as a method of pain…
- Trial name
- NCT04983511
- Testing
- Electrical Epidural Stimulation Test (EST)
- Volunteers
- 40 people
- Sponsor
- Stanford University
Hypotension, Spinal Anesthesia
Prophylactic Ondansetron for Preventing Spinal Anesthesia-Induced Hypotension in Elective Cesarean Section
Spinal anesthesia is the preferred technique for elective cesarean section, but it frequently causes maternal hypotension due to sympathetic blockade and the Bezold-Jarisch reflex, which can threaten both mother and baby.
- Conditions
- Hypotension, Spinal Anesthesia, Cesarean Section
- Trial name
- NCT07886151
- Testing
- Ondansetron
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Post-Dural Puncture Headache
Bilateral Sphenopalatine Ganglion Block With or Without Bilateral Greater Occipital Nerve Block for Treatment of Obstetric Post-Dural Puncture Headache
Post-dural puncture headache is a common complication, following neuraxial techniques. The obstetric population is particularly prone to PDPH. Therefore, treatment of PDPH is a key issue in obstetric anesthesia.
- Trial name
- NCT04844229
- Testing
- Bilateral transnasal sphenopalatine ganglion block., Bilateral ultrasound guided greater occipital nerve block.
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Pregnancy Complications, Cesarean Section Complications
A Quality Improvement Project - Peripartum Operating Room Leveling System
Investigators propose a four-category triaging system to delineate and facilitate the communication and action plan for all types of obstetric OR cases via a multidisciplinary approach.
- Conditions
- Pregnancy Complications, Cesarean Section Complications, Morbidity;Perinatal
- Trial name
- NCT03552419
- Volunteers
- 1,380 people
- Sponsor
- Johns Hopkins University
Postoperative Pain, Cesarean Section
Intrathecal Morphine 75 mcg Versus 100 mcg for Post-Cesarean Analgesia: A Randomized Double-blind Trial
This study evaluates the efficacy and safety of two different doses of intrathecal morphine (75 mcg versus 100 mcg) for postoperative analgesia in patients undergoing elective cesarean delivery under spinal anesthesia.
- Conditions
- Postoperative Pain, Cesarean Section, Obstetric Anesthesia
- Trial name
- ITM-CESAREAN (NCT07516717)
- Testing
- Intrathecal Morphine
- Where
- Venezuela
- Volunteers
- 240 people
- Sponsor
- Hospital Universitario de Caracas
Pregnancy
Comparison of Echo-assisted ALR Technique and Traditional ALR Technique for the Placement of an Epidural Catheter in the Obstetric Patient
This is a randomized, open-label, single-center clinical trial. The purpose of the study is to understand whether the aid of ultrasound assessment is useful in improving the competence of resident.
- Trial name
- OST-22-01 (NCT06811649)
- Testing
- Ultrasound guided injection with local anaestethic
- Where
- Italy
- Volunteers
- 146 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Hypotension Symptomatic, Vasoconstriction
Colloid Co-hydration and Vasoconstrictor Infusion for Prevention of Hypotension During Cesarean Section
This will be a double-blind randomized study, aiming at investigating a fixed rate phenylephrine infusion versus a fixed rate norepinephrine infusion versus placebo in combination with co-hydration with colloids for the…
- Conditions
- Hypotension Symptomatic, Vasoconstriction, Cesarean Section Complications, Obstetric Anesthesia Problems
- Trial name
- annie-zoe (NCT04404946)
- Testing
- phenylephrine infusion, norepinephrine infusion
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- Aretaieion University Hospital
Obstetric Anesthesia Care
Obstetric Anesthesia and Analgesia Month Attributes in Czech Republic
A national survey of current practices, preferred drug and technique choices for obstetric anesthesia and analgesia in Czech Republic.
- Trial name
- OBAAMA (NCT01830218)
- Testing
- Obstetric anesthesia and analgesia
- Where
- Czechia
- Volunteers
- 1,940 people
- Sponsor
- Charles University, Czech Republic
Labour Pain
Combined Spinal-Epidural Versus Traditional Labor Epidural
The purpose of this study to compare the use of spinal-epidural versus traditional labor epidural on maternal and fetal effects.
- Trial name
- NCT00151346
- Testing
- Bupivacaine and Fentanyl (for CSE), Bupivacaine and Fentanyl (for traditional epidural)
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Hemodynamic Instability
Effect of Intravenous Ketamine Infusion for Hemodynamic Stability in Patients Undergoing Caesarean Delivery.
Hypotension is the most frequent side effect of intrathecal anesthesia, with a found incidence of more than 80%. With a frequency of between 40% and 60% in patients undergoing surgery, Perioperative shivering is a serious…
- Trial name
- NCT05865080
- Testing
- Ketamine
- Where
- Egypt
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Breech Presentation; Before Labor
Spinal Anesthesia for External Cephalic Version
This study evaluates the potential benefits of spinal anaesthesia for nulliparous mothers scheduled for external version of babies in breech position.
- Trial name
- NCT03797833
- Testing
- Spinal Anaesthesia
- Where
- 2 sites in Sweden
- Volunteers
- 200 people
- Sponsor
- Region Skane