Clinical trials: Obsessive-Compulsive Symptoms
Major Depressive Episode (MDE), Major Depressive Disorder (MDD)
LHC-CIDI-5 in Hong Kong
The World Health Organization Composite International Diagnostic Interview-5th (CIDI-5) is a standardized diagnostic tool used to assess the prevalence of mental and substance use disorders over varying time frames (30 days, 12…
- Conditions
- Major Depressive Episode (MDE), Major Depressive Disorder (MDD), Persistent Depressive Disorder (PDD), Suicidal Ideation
- Trial name
- NCT06804525
- Testing
- CIDI-5, LHC-CIDI-5
- Where
- Hong Kong
- Volunteers
- 2,500 people
- Sponsor
- The University of Hong Kong
Skin-Picking
Skin Picking Approach Avoidance Task
Pathological skin picking (PSP) is conceptualized as a behavioral addiction. Research has shown that behavioral addictions (e.g., problematic alcoholism or smoking) can be reduced using a cognitive retraining tool called…
- Trial name
- SPAAT (NCT04099537)
- Testing
- Computerized cognitive training
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Wisconsin, Milwaukee
Obsessive Compulsive Disorder
Neural Mechanisms of CBT Response in Hoarding Disorder
The purpose of this research is to measure changes in brain activity with functional magnetic resonance imaging (fMRI) before and after cognitive-behavioral therapy for compulsive hoarding.
- Trial name
- NCT01956344
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Obsessive-compulsive Disorders and Symptoms
tDCS Stimulation to Treat Patients With Severe and Resistant Obsessive Compulsive Disorder-Pilot Study
The purpose is to show that bifocal tDCS with an anodal stimulation on the orbitofrontal cortex and cathodic stimulation on supplementary motor areas is an effective treatment for patients with resistant and severe obsessive…
- Trial name
- tDCS-TOC (NCT03284671)
- Testing
- bifocal stimulation with tDCS
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Henri Laborit
Obsessive-Compulsive Disorder
tDCS Associated With Symptom Provocation in the Management of Patients With Resistant Obsessive Compulsive Disorder
This is a single-center study about patients with severe resistant OCD. Main assumption is that performing 10 tDCS sessions with the anode positioned at the level of the right orbitofrontal cortex, and the cathode at the level of…
- Trial name
- PPSTDCS-TOC (NCT06017713)
- Testing
- tDCS + symptoms provocation
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Henri Laborit
Tourette Syndrome, Obsessive Compulsive Disorder
Study of the Neurobiology of Tourette Syndrome and Related Disorders
OBJECTIVES: I. Investigate the pathobiology of Tourette syndrome and related disorders by measuring various compounds of interest in cerebrospinal fluid, plasma, and urine of patients with Tourette syndrome, obsessive compulsive…
- Trial name
- NCT00004325
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Center for Research Resources (NCRR)
Social Anxiety, Generalized Anxiety
Imagery Rescripting and Imaginal Exposure for Anxiety Symptoms
This study will recruit 460 participants who self-report high symptoms of anxiety. Participants will be randomly assigned to one of 4 groups: one analog intervention of Imagery Rescripting (IR) for memories, an analog…
- Conditions
- Social Anxiety, Generalized Anxiety, Obsessive-Compulsive Symptom, Panic
- Trial name
- NCT05292807
- Testing
- Imaginal exposure for memories, Imaginal exposure for future events, Imagery rescripting for memories
- Where
- Israel
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Hebrew University of Jerusalem
Skin-Picking, Trichotillomania (Hair-Pulling Disorder)
Behavioral Treatment and Memantine in Body Focused Repetitive Behaviors
The goal of the proposed study is to compare the efficacy of behavioral treatment (BT) to memantine, a psychopharmacological agent, for BFRBs.
- Trial name
- NCT05796752
- Testing
- Memantine, ComB Behavioral Therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Chicago
Obsessive-Compulsive Disorder
Effect of the French Version If the Metagognitive Bibliotherapy Program "MYMCT" on Obsessive-compulsive Symptoms
Obsessive-compulsive disorder (OCD) is a psychiatric illness characterized by the presence of obsessions and/or compulsions. Without effective treatment, symptoms tend to worsen and become chronic.
- Trial name
- M-TOC (NCT06494735)
- Testing
- MyMCT
- Where
- France
- Volunteers
- 114 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Obsessive-compulsive Disorder, Depression
Rechargeable Neurostimulators in Deep Brain Stimulation for Psychiatric Disorders
From 1999 onwards, Deep Brain Stimulation [DBS] has been proposed as an alternative to capsulotomy in refractory cases of Obsessive-Compulsive Disorder [OCD].
- Trial name
- NCT02685280
- Testing
- Medtronic Restore Advanced 37713
- Volunteers
- 12 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
OCD, Obsessive - Compulsive Disorder
Effect of Emotion-Focused Acceptance and Commitment Therapy on Obsessive-Compulsive Disorder Symptom Severity
This study aims to investigate the effect of Emotion-Focused Acceptance and Commitment Therapy (ACT) group psychotherapy on obsessive-compulsive disorder (OCD) symptom severity.
- Trial name
- ACT-OCD (NCT07622654)
- Testing
- Emotion-Focused Acceptance and Commitment Therapy (ACT) Group Psychotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Mehmet Emrah Karadere
Emotional Regulation, Depression
A Precision Medicine Approach to Target Engagement for Emotion Regulation
The proposed study is designed to first test whether teaching people personalized or standardized emotion regulation skills leads to greater decreases in daily negative emotion intensity.
- Conditions
- Emotional Regulation, Depression, Anxiety, Borderline Personality Disorder
- Trial name
- NCT05651295
- Testing
- Checking the Facts, Opposite to Emotion Action, Mindfulness of Current Emotions
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- Matthew Southward, PhD
Trichotillomania, Alexithymia
Online Treatment of Trichotillomania
Online study for patients with trichotillomania. 4 main hypothesis. 1. Alexithymia and Trichotillomania correlated and regression analyses find association between them 2.
- Conditions
- Trichotillomania, Alexithymia, Quality of Life
- Trial name
- NCT02044237
- Testing
- Decoupling, Progressive relaxation
- Where
- Switzerland
- Volunteers
- 105 people
- Sponsor
- University of Zurich
Depression, Obsessive-Compulsive Disorder
Retrospective Analyses of TrakStar Database
In this study, real-world data will be used to better understand the effects patient characteristics, symptoms and TMS protocol parameters have on clinical outcomes with NeuroStar TMS.
- Conditions
- Depression, Obsessive-Compulsive Disorder, Anxiety Depression
- Trial name
- NCT06917339
- Testing
- NeuroStar Advanced TMS Therapy System
- Where
- United States
- Volunteers
- 156,000 people
- Sponsor
- Neuronetics