Clinical trials: Obsessive Compulsive Disorder (OCD)
Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)
Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)
Background: PANS is an illness that comes on suddenly in children. The full name is Pediatric Acute-Onset Neuropsychiatric Syndrome. It can cause sudden obsessive-compulsive behaviors.
- Trial name
- NCT03507218
- Where
- 8 sites in United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Hoarding Disorder
Cognitive Rehab and Exposure Treatment for Hoarding
This project will utilize a novel behavioral intervention for hoarding disorder that takes into account age and neurocognitive factors.
- Trial name
- CREST (NCT02402647)
- Testing
- Cognitive Rehabilitation and Exposure/Sorting Treatment (CREST), Exposure Therapy (ET)
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Obsessive-Compulsive Disorder
Efficacy and Influencing Factors of Deep Transcranial Magnetic Stimulation in the Treatment of OCD
This study aims to explore the efficacy and influencing of accelerated dTMS (deep Transcranial Magnetic Stimulation) treatment in patients with obsessive-compulsive disorder (OCD), and explores the potential neural mechanisms of…
- Trial name
- NCT06692114
- Testing
- Deep Transcranial Magnetic Stimulation, DTMS active
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Zhen Wang
Obsessive-Compulsive Disorder
An OCD Prevention Programme for at Risk Adults
The main purpose of this randomised clinical trial is to test the efficacy of a prevention program for adult who are at risk of developing OCD, thus constituting a form of tertiary prevention.
- Trial name
- ØCD (NCT06262464)
- Testing
- Prevention
- Where
- Romania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Obsessive-Compulsive Disorder
Effectiveness of a Self-guided Mobile Application in Improving Obsessive Compulsive Disorder Symptoms
Obsessive Compulsive Disorder (OCD) is a significant mental health problem worldwide. OCD typically begins in young adulthood, and without adequate intervention, often takes a chronic course.
- Trial name
- NCT06202677
- Testing
- Self-guided program on obsessive compulsive disorder, Self-guided program on cooperation
- Where
- Singapore
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Obsessive-Compulsive Disorder (OCD)
Intensive Cognitive-Behavioral Therapy For Obsessive-Compulsive Disorder
Even with the best available treatments for obsessive-compulsive disorder (OCD), most patients only partially recover and many patients do not respond at all.
- Trial name
- NCT01368510
- Testing
- Intensive Cognitive Behavioral Therapy (CBT), Waitlist
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
ADHD, Obsessive Compulsive Disorder (OCD)
Role of Theta Frequency Oscillations in Proactive and Reactive Control Processes in Youth With Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD)
Background: Attention deficit hyperactivity disorder (ADHD) is common in children. It can cause problems with attention and the ability to control actions and impulses.
- Conditions
- ADHD, Obsessive Compulsive Disorder (OCD), Healthy Volunteer
- Trial name
- NCT07566468
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Hoarding Disorder, Obsessive-Compulsive Disorder
Cognitive Rehabilitation and Exposure Therapy for Geriatric Hoarding
Hoarding disorder (HD) is a chronic, progressive, and debilitating psychiatric condition that leads to devastating personal and public consequences, particularly for older adults.
- Trial name
- CREST (NCT05254015)
- Testing
- Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST), Case Management
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obsessive Compulsive Disorder OCD
Impact of Attention on Obsessive Thoughts Through THOUGHT
Impact of attention on obsessive through the THOUGHT-scale (Troublesome Human Obsessions and Untargeted General Habitual Thoughts Scale): a description of the content of thoughts according to the level of attention demanded by…
- Trial name
- THOUGHTS (NCT05944172)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obsessive-Compulsive Disorder
Fear Conditioned Response in Healthy Subjects and in OCD Patients Pre and Post Treatment With Sertraline.
24 OCD patients and 24 healthy subjects will be submitted to a two-day fear conditioning paradigm during acquisition of functional magnetic resonance imaging (fMRI).
- Trial name
- FEARCON (NCT03068429)
- Testing
- Sertraline Hydrochloride
- Where
- Brazil
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Obsessive-Compulsive Disorder
Characterize The Modulatory Effects Of Dopamine D2/D3 Receptor Agonist And Antagonist Drugs On Compulsive Behaviors
3 groups of subjects (healthy controls, OCD subjects and stimulant-dependent subjects) will receive pramipexole (1.5 mg, single dose), amisulpride (400 mg, single dose) or placebo in a cross-over, double-blind, placebo-controlled…
- Trial name
- NCT00471588
- Testing
- Pramipexole, Amisulpride
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Depression, Obsessive-Compulsive Disorder
Pharmacogenetics in Primary Care Psychotropics
Pragmatic trial of pharmacogenetic testing at the time of prescription for a selective serotonin reuptake inhibitor, tricyclic antidepressant or atypical antipsychotic. Does real time intervention improve patient outcomes?
- Conditions
- Depression, Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
- Trial name
- NCT03232502
- Testing
- Pharmacogenetic testing
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Obsessive-Compulsive Disorder
Cognitive Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder
This study will examine the way cognitive behavioral therapy changes the structure of the brain in patients with obsessive-compulsive disorder and will thereby determine what makes cognitive behavioral therapy an effective…
- Trial name
- NCT00748761
- Testing
- Cognitive Behavioral Therapy (CBT), Waitlist
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Obsessive-Compulsive Disorder
Neurocircuit Mechanisms of OCD Across the Lifespan
Obsessive-compulsive disorder (OCD), characterized by intrusive thoughts (obsessions) and related behavioral rituals (compulsions), is a common psychiatric illness that often emerges in childhood and causes life-long disability…
- Trial name
- NCT02437773
- Testing
- Cognitive Behavioral Therapy - Adolescents, Stress Management Therapy - Adolescents, Optional CBT - Adolescents
- Where
- United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Anxiety Disorders, Depressive Disorder
Transdiagnostic Treatment Personalization
The primary purpose of this study is to explore whether the efficiency of treatment for anxiety and depressive disorders can be increased using two discrete strategies: personalized skill ordering and 2) treatment discontinuation…
- Conditions
- Anxiety Disorders, Depressive Disorder, Post Traumatic Stress Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT04584879
- Testing
- Standard UP Treatment, Capitalization UP Treatment, Compensation UP Treatment
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Obsessive Compulsive Disorder
Neural Mechanisms of CBT Response in Hoarding Disorder
The purpose of this research is to measure changes in brain activity with functional magnetic resonance imaging (fMRI) before and after cognitive-behavioral therapy for compulsive hoarding.
- Trial name
- NCT01956344
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Obsessive-Compulsive Disorder
Neurocircuitry of Obsessive-Compulsive Disorder: Modulation by Transcranial Magnetic Stimulation
The purpose of this study is to test the effects of non-invasive neuromodulation, transcranial magnetic stimulation on brain function in individuals with obsessive-compulsive disorder (OCD).
- Trial name
- NCT02704117
- Testing
- Transcranial Magentic Stimulation
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Anorexia Nervosa, Obsessive-Compulsive Disorder
Radical Openness for Adolescents Pilot
Heightened performance monitoring and overcontrol (HPM/OC) is characterized by inflexibility, a need for control, perfectionism, anxious apprehension and high error monitoring.
- Conditions
- Anorexia Nervosa, Obsessive-Compulsive Disorder, Social Phobia, Depression, Anxiety
- Trial name
- ROA (NCT05913557)
- Testing
- Radically Open Dialectical Behavior Therapy (RO DBT)
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obsessive Compulsive Disorder
Treatment Youth With Obsessive-Compulsive Disorder
Although research suggests that patients with obsessive-compulsive disorder (OCD) exhibit specific deficits in their high cognitive processes, it is still unknown how these deficits relate to the clinical symptoms of the…
- Trial name
- NCT00708240
- Testing
- Escitalopram
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Obsessive-Compulsive Disorder
Neural Correlates of Compulsivity
This study aims to collect data from individuals with obsessive-compulsive disorder (OCD) and healthy controls in order to clarify how learning strategies are employed differently by individuals with compulsive psychopathology…
- Trial name
- NCT05195476
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Columbia University