Clinical trials: Obsessive Compulsive Disorder
Obsessive-Compulsive Disorder, OCD
Personalized DBS for OCD Guided by Stereoencephalography Mapping
This is a double-blinded, randomized, crossover study design for SEEG-guided 4-lead DBS for treatment-refractory OCD, followed by open label stimulation for an additional 6 months.
- Trial name
- NCT06347978
- Testing
- Deep Brain Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Andrew Moses Lee, MD, PhD
Panic Disorder, Generalized Anxiety Disorder
Collabri Flex - Effect of Collaborative Care for People With Anxiety Disorders in General Practice
The aim of the study Collabri Flex is to: Develop a Danish model for collaborative care for patients with anxiety in general practice, based on past experience gained in the Collabri Project.
- Conditions
- Panic Disorder, Generalized Anxiety Disorder, Social Phobia, Obsessive-Compulsive Disorder
- Trial name
- NCT03113175
- Testing
- Collaborative care, Consultations-Liaison
- Where
- Denmark
- Volunteers
- 302 people
- Sponsor
- Amager Hospital
OCD
The Imaging Genetic Study of the Core Family of Obsessive-compulsive Disorder (OCD) Patient
To investigate the structural/functional abnormalities and the possible genetic endophenotypes of Obsessive-compulsive disorder (OCD) patients and their core families.
- Trial name
- NCT01298622
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kunming Medical University
Obsessive-compulsive Disorder
Evaluating the Feasibility, Safety and Efficacy of Psychotherapy Assisted Psilocybin for Treatment of Severe OCD
Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder characterized by recurrent distressing thoughts and substantial anxiety, accompanied by repetitive behaviors or mental rituals.
- Trial name
- NCT04882839
- Testing
- psychotherapy assisted psilocybin
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Beersheva Mental Health Center
Obsessive-Compulsive Disorder
Acceptance and Commitment Therapy in SSRI-Resistant Obsessive Compulsive Disorder
The purpose of this study is to determine whether acceptance and commitment therapy is effective in the treatment of SSRIs-resistant obsessive- compulsive disorder.
- Trial name
- NCT02955654
- Testing
- Acceptance and commitment therapy, Aripiprazole, Stress management training
- Sponsor
- Shanghai Mental Health Center
Trichotillomania, Alexithymia
Online Treatment of Trichotillomania
Online study for patients with trichotillomania. 4 main hypothesis. 1. Alexithymia and Trichotillomania correlated and regression analyses find association between them 2.
- Conditions
- Trichotillomania, Alexithymia, Quality of Life
- Trial name
- NCT02044237
- Testing
- Decoupling, Progressive relaxation
- Where
- Switzerland
- Volunteers
- 105 people
- Sponsor
- University of Zurich
Depression, Obsessive-Compulsive Disorder
Retrospective Analyses of TrakStar Database
In this study, real-world data will be used to better understand the effects patient characteristics, symptoms and TMS protocol parameters have on clinical outcomes with NeuroStar TMS.
- Conditions
- Depression, Obsessive-Compulsive Disorder, Anxiety Depression
- Trial name
- NCT06917339
- Testing
- NeuroStar Advanced TMS Therapy System
- Where
- United States
- Volunteers
- 156,000 people
- Sponsor
- Neuronetics
Obsessive Compulsive Disorder (OCD), Comorbid Post-Traumatic Stress Disorder and OCD
ERP to Improve Functioning in Veterans With OCD
Obsessive compulsive disorder (OCD) is a debilitating psychiatric illness impacting work, social, and family functioning. Exposure and Response Prevention (ERP) is the sole evidence-based psychotherapy for OCD; however, no…
- Trial name
- NCT05240924
- Testing
- Exposure and Response Prevention, Stress Management Training
- Where
- 19 sites in United States
- Volunteers
- 160 people
- Sponsor
- VA Office of Research and Development
Trichotillomania
Awareness Enhancement and Monitoring Device for Treatment of Trichotillomania
The goals of the study are to further design, develop, and test an awareness enhancement and monitoring device, which will be used in the self-awareness training and general treatment of patients with compulsive hair-pulling…
- Trial name
- NCT01654523
- Testing
- Awareness Enhancement and Monitoring Device for Treatment of Trichotillomania
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Michigan
Obsessive-Compulsive Disorder
Sonication-based OCD Neurosurgical Intervention Via Capsulotomy
The goal of this clinical trial is to determine if ExAblate MR-guided Focused Ultrasound (MRgFUS) bilateral anterior capsulotomy can be used safely and effectively to relieve symptoms of moderate to severe obsessive compulsive…
- Trial name
- SONIC (NCT06131502)
- Testing
- ExAblate MR-guided Focused Ultrasound Bilateral Anterior Capsulotomy
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- Brigham and Women's Hospital
Obsessive Compulsive Disorder OCD
Impact of Attention on Obsessive Thoughts Through THOUGHT
Impact of attention on obsessive through the THOUGHT-scale (Troublesome Human Obsessions and Untargeted General Habitual Thoughts Scale): a description of the content of thoughts according to the level of attention demanded by…
- Trial name
- THOUGHTS (NCT05944172)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obsessive-Compulsive Disorder
Brain Recordings in Patients Undergoing Deep Brain Stimulation (DBS) for Severe Obsessive-Compulsive Disorder (OCD)
Obsessive-compulsive disorder effects approximately 2-3% of the population. The only established first-line treatments for OCD are cognitive-behavioral therapy (CBT) with exposure/response prevention and serotonin reuptake…
- Trial name
- NCT05915741
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Baylor College of Medicine
Obsessive Compulsive Disorder
SONATA LIFU for OCD
The study tests ATTN201, an investigational non-invasive headband that delivers low-intensity focused ultrasound (LIFU) to the subthalamic nucleus (STN) as a treatment for obsessive-compulsive disorder (OCD).
- Trial name
- NCT07728994
- Testing
- Low Intensity Focused Ultrasound
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pennsylvania
Obsessive-Compulsive Disorder (OCD)
Impact of EsTOCma on OCD Family Members
The goal of this clinical trial is to test the acceptability, feasibility, and effectiveness of esTOCma in families and relatives of individuals with obsessive-compulsive disorder (OCD).
- Trial name
- esTOCma family (NCT06616350)
- Testing
- esTOCma: an app to fight stigma associated with OCD
- Where
- Spain
- Volunteers
- 211 people
- Sponsor
- University of Valencia
Obsessive-Compulsive Disorder
Evaluation of the Long Term Efficacy and Durability of the BrainsWay Deep TMS in OCD Subjects
A Prospective Double Blind Randomized Controlled Trial to Evaluate the Long Term Efficacy and Durability of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) in Obsessive-Compulsive Subjects
- Trial name
- NCT05404360
- Testing
- BrainsWay Deep TMS HAC/H7-Coil
- Volunteers
- 124 people
- Sponsor
- Brainsway
Hoarding Disorder, Attentional Impairment
Cognitive Remediation for Neuropsychological Impairment in Compulsive Hoarding
The primary aim of this pilot randomized controlled trial is to examine whether cognitive remediation, compared to a placebo, improves attention and related cognitive functions in patients with compulsive hoarding.
- Trial name
- NCT01451697
- Testing
- Cognitive Remediation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hartford Hospital
Obsessive-Compulsive Disorder
Transcranial Direct Current Stimulation (tDCS) in the Treatment of Drug-naïve Obsessive-compulsive Disorder(OCD)
This study will evaluate the possible therapeutic effects of Transcranial Direct Current Stimulation (tDCS) in drug-naïve obsessive-compulsive disorder (OCD) patients, and the underlying neural mechanism by magnetic resonance…
- Trial name
- NCT04086446
- Testing
- high-definition transcranial direct current stimulation
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Shanghai Mental Health Center