Clinical trials: Obsessive Compulsive Disorder
Obsessive-Compulsive Disorder, Tic Disorder
Pathogenesis of Pediatric Obsessive-compulsive Disorder: Based on the Microbiota-gut-brain Axis
This study aims to investigate the characteristics of the microbiota-gut-brain axis in pediatric patients with obsessive-compulsive disorder (OCD) through performing an integrated analysis of gut microbiota, serum metabolomics…
- Trial name
- NCT06754319
- Where
- China
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Obsessive - Compulsive Disorder
tDCS and Symptom Provocation in Treatment-Resistant OCD
The goal of this clinical trial is to learn if symptom provocation before transcranial Direct Current Stimulation (tDCS) in Obsessive-Compulsive Disorder (OCD) patients.
- Trial name
- PPS-TDCSTOC (NCT07429500)
- Testing
- tDCS session, symptom provocation
- Where
- 6 sites in France
- Volunteers
- 178 people
- Sponsor
- Centre Hospitalier Henri Laborit
Hoarding Disorder, Hoarding
Hoarding Disorder Treatment With Virtual Reality
This study explores whether a facilitated peer support group called Buried in Treasures (BIT) and a virtual reality decluttering practice can help individuals with clutter challenges.
- Conditions
- Hoarding Disorder, Hoarding, Clutter
- Trial name
- HDVR (NCT03828461)
- Testing
- Facilitated group therapy with behavioral practice; 16 weeks
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Stanford University
Obsessive-Compulsive Disorder (OCD)
Exploring The Metacognitive Beliefs in OCD: A Randomized Controlled Trial of Metacognitive Therapy
Exploring The Metacognitive Beliefs in OCD: A Randomized Controlled Trial of Metacognitive Therapy Introduction Obsessive-Compulsive Disorder (OCD) is a mental health condition characterized by intrusive thoughts (obsessions) and…
- Trial name
- MCT-OCD (NCT07052812)
- Testing
- MCT
- Where
- 2 sites in Pakistan
- Volunteers
- 76 people
- Sponsor
- Northeast Normal University
Obsessive-Compulsive Disorder
Mindfulness-Based Cognitive Therapy: Efficacy and fMRI-based Response Predictors in a Group of OCD Patients
Obsessive-Compulsive Disorder (OCD) patients have a response rate of 50-60% to exposure and response prevention (ERP) therapy and SSRI antidepressants.
- Trial name
- NCT03128749
- Testing
- Mindfulness Based Intervention, Treatment as Usual
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Corporacion Parc Tauli
Aneurysms, Arteriovenous Malformations
Neurosurgical Outcome Network
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared.
- Conditions
- Aneurysms, Arteriovenous Malformations, Cavernomas, Skull Base Tumors
- Trial name
- NEON (NCT06724029)
- Where
- 27 sites in Italy
- Volunteers
- 4,500 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Obsessive-Compulsive Disorder
Initial Development and Dissemination of OC-Go
The clinical component of Phase I application development examines the clinical utility, feasibility, and functionality of the OC-Go application via an 8-month pilot trial consisting of 50 standard CBT sessions augmented with…
- Trial name
- OC-GoPhaseI (NCT03126305)
- Testing
- OC-Go
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, Los Angeles
Obsessive-Compulsive Disorder
What Are You Looking for? Psychometric and Experimental Analyses of Reassurance Seeking in Obsessive-compulsive Disorder
This study evaluates the efficacy and acceptability of two cognitive-behavioural interventions for reassurance seeking behaviour in obsessive-compulsive disorder (OCD), a family accommodation reduction protocol vs.
- Trial name
- NCT02909660
- Testing
- Cognitive-behavioural therapy
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- Concordia University, Montreal
Adult ALL, Post-traumatic Stress Disorder
Effects of an EMDR Intervention on Traumatic and Obsessive Symptoms
The Eye Movement Desensitization and Reprocessing Protocol (EMDR) was first developed by Francine Shapiro in 1987 and can be adapted for online and in presence administration.
- Conditions
- Adult ALL, Post-traumatic Stress Disorder, Obsessive-Compulsive Disorder, Disgust
- Trial name
- MDL (NCT06110702)
- Testing
- EMDR
- Where
- Italy
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Hoarding Disorder
Motivational Interviewing to Enhance Behavioral Change in Older Adults With Hoarding Disorder
This study will compare two behavioral interventions for hoarding disorder in older adults.
- Trial name
- NCT05237466
- Testing
- RECLAIM: Reducing Clutter and Increasing Meaning, Sorting Practice
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Mississippi State University
Obsessive-Compulsive Disorder
The Safety and Efficacy of Long-term Treatment of PINS Stimulator System for Patients With Obsessive-Compulsive Disorder
The purpose of this clinical study is To verify the long term effectiveness and safety of a bilateral deep brain stimulation (DBS) produced by Beijing PINS Medical Co., Ltd.
- Trial name
- NCT02253472
- Testing
- Deep Brain Stimulation
- Volunteers
- 30 people
- Sponsor
- Beijing Pins Medical Co., Ltd
Obsessive-Compulsive Disorder
Neurofeedback for Obsessive-Compulsive Disorder (OCD)
The aim of this study is to train patients with obsessive-compulsive disorder to control a region of their brain that has been associated with their symptoms.
- Trial name
- NCT02206945
- Testing
- neurofeedback, control feedback
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Yale University
OCD
Does TMS Affect Neuroplasticity? The Role of Brain-derived Neurotrophic Factor and Neuronal Cell Adhesion Molecules - an Intensive Clinical Protocol Among Patients With Obsessive-compulsive Disorders
Patients expressing interest in participating will undergo psychiatric assessment to verify the diagnosis of treatment-resistant obsessive-compulsive disorder (OCD), assess symptom severity, and exclude TMS contraindications.
- Trial name
- NCT06231095
- Testing
- continuous theta burst stimulation - cTBS
- Where
- 2 sites in Poland
- Volunteers
- 40 people
- Sponsor
- Wroclaw Medical University
Obsessive Compulsive Disorder, Body Dysmorphic Disorder
Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals
To examine the effectiveness and clinical care outcomes of cognitive-behavioral therapy interventions at Massachusetts General Hospital (MGH).
- Conditions
- Obsessive Compulsive Disorder, Body Dysmorphic Disorder, Tourette Syndrome, Trichotillomania
- Trial name
- NCT01075672
- Testing
- Cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Massachusetts General Hospital
Obsessive-Compulsive Disorder
Psycho-education Intervention for Postpartum OCD and it's Influence on Symptom Severity and Treatment Self Referral Rates
The rationale for conducting the experiment including quantitative measures and a description of the method of recruitment: This study provides psycho-educational intervention aimed at raising awareness of post partum…
- Trial name
- NCT03172728
- Testing
- psycho-education pamphlet
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obsessive Compulsive Disorder
CBT for Pediatric OCD: Community Training Pilot
This study examines a training program for clinicians who work in mental health clinics that serve children with OCD. We will provide clinician training in conducting exposure-based treatments for children with OCD.
- Trial name
- NCT02202915
- Testing
- Behavioral Checklist
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Rhode Island Hospital
Obsessive-compulsive Disorder, Ocd
Riluzole Augmentation in Treatment-refractory Obsessive-compulsive Disorder
Obsessive-compulsive disorder (OCD) affects 2-3% of the population and leads to a great deal of suffering. Many patients benefit from established treatments, the mainstay of which are cognitive behavioral therapy and a group of…
- Trial name
- NCT00523718
- Testing
- riluzole
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Yale University
OCD
Therapist Guided, Parent-led, Cognitive Behavioural Therapy (CBT) for Preadolescent Children With Obsessive Compulsive Disorder (OCD)
This preliminary study aims to examine the outcomes from a therapist guided, parent-led, CBT treatment for preadolescent children (aged 5 to 12 years old) with OCD. Specifically, this study aims to: 1.
- Trial name
- NCT05981690
- Testing
- Therapist guided, parent-led CBT for preadolescent children with OCD
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Reading
Obsessive-Compulsive Disorder
The Neurocircuitry of Relief During Avoidance Learning in Patients With Obsessive-compulsive Disorder
To investigate the neuro-mechanisms underpinning persistent avoidance in OCD patients
- Trial name
- AvoidOCD (NCT04685018)
- Testing
- fMRI acquisition
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KU Leuven
OCD, Obsessive-Compulsive Disorder
Locating Biomarkers in OCD Through Behavioral Tasks
Subjects that have a diagnosis of OCD will participate in a clinical interview and cognitive tasks, during which they will be exposed to their individual OC stressors or will be asked to make decisions related to information…
- Trial name
- NCT03313622
- Testing
- Beads Task, PROVOC Tasks
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine