Clinical trials: Obsessive Compulsive Behavior
Tobacco Use Disorder, Smoking Cessation
Deep rTMS and Varenicline for Smoking Cessation
The purpose of this study is to investigate the effect of deep repetitive transcranial magnetic stimulation (rTMS) using the insula H-coil on smoking outcomes in smokers receiving varenicline.
- Trial name
- NCT04083144
- Testing
- Deep Repetitive Transcranial Magnetic Stimulation (Active), Varenicline
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Centre for Addiction and Mental Health
Prader-Willi Syndrome, Obesity
Effects of Transcranial Direct Current Stimulation (tDCS) on Individuals With Prader-Willi Syndrome
Prader-Willi Syndrome (PWS) is a multisystemic genetic disease characterized by hypotonia, mental retardation, hyperphagia, and uncontrollable hunger due to hypothalamic dysfunction, caused by dysregulation of genes located in…
- Conditions
- Prader-Willi Syndrome, Obesity, Depressive Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT03324906
- Testing
- tDCS
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Addiction, Alcohol Use Disorder
Semaglutide Therapy for Alcohol Reduction (STAR)
Background: Alcohol use disorder (AUD) is a problematic pattern of alcohol use accompanied by clinically significant medical consequences.
- Trial name
- NCT06015893
- Testing
- Take Control, Semaglutide
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Internet Addiction Disorder
Evaluation of a Therapeutic Education Application in the Treatment of Young People with Moderate or Problematic Screen Use
This single-center, controlled, and randomized study evaluates the effectiveness of the Phonix Care app in regulating screen use among young people aged 11 to 25.
- Trial name
- PHONIX CARE (NCT06648538)
- Testing
- Phonix Care
- Where
- France
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Obsessive-Compulsive Disorder
Risperidone or Cognitive-Behavioral Therapy for Improving Medication Treatment for Obsessive-compulsive Disorder
This study will compare the short- and long-term effectiveness of two common therapies in improving serotonin reuptake inhibitor treatment in people with obsessive-compulsive disorder.
- Trial name
- NCT00389493
- Testing
- Risperidone, Exposure/ritual prevention therapy (EX/RP)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- New York State Psychiatric Institute
Tension-Type Headache, Sleep Disturbance
Tension-type Headache and Its Association
To estimate the prevalence of tension-type headache among adults attending the outpatient clinics at Assiut University Hospitals, and to assess its association with smartphone use, sleep quality, and quality of life.
- Conditions
- Tension-Type Headache, Sleep Disturbance, Smartphone Addiction, Quality of Life
- Trial name
- NCT07779655
- Volunteers
- 199 people
- Sponsor
- Assiut University
Obesity, Obesity, Morbid
Deep Brain Stimulation for Morbid Obesity
This is an open-label, phase I pilot trial designed to evaluate the safety and feasibility of deep brain stimulation (DBS) for the treatment of refractory morbid obesity.
- Trial name
- NCT03650309
- Testing
- Deep Brain Stimulation
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- University Health Network, Toronto
Smartphone Addictions
Examining the Effects of Fatigue According to Nomophobia Level
The aim of this study is to examine, using a comparative and experimental approach, the effects of nomophobia (fear of being without a smartphone) levels on acute neuromuscular and cognitive fatigue susceptibility induced by a…
- Trial name
- NCT07487922
- Testing
- Fatigue Induction Procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Inonu University
Internet Addiction
Efficacy of Escitalopram in the Treatment of Internet Addiction
The purpose of this study was to determine whether Lexapro (Escitalopram) is safe and effective in treating problematic internet use.
- Trial name
- NCT00565422
- Testing
- Escitalopram
- Volunteers
- 31 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pain, Pain, Acute
Assessing Opioid Care Practices Using CPV Patient Simulation Modules
This study will test the quality of opioid-related physician care decisions using a patient-simulation based measurement and feedback approach that combines multiple-choice care decisions with real-time, personalized scoring and…
- Conditions
- Pain, Pain, Acute, Pain, Chronic, Pain, Neuropathic
- Trial name
- NCT04080037
- Testing
- Quality IQ Patient Simulations
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Tobacco Use Disorder
Increasing Smoking Cessation Success Through Sleep-amplified Memory Consolidation
The goal of this subproject is to examine the hypothesized improvement of treatment with chess-based training and sleep enhancement, both together and on their own, in smokers.
- Trial name
- NCT05726045
- Testing
- Standard smoking cessation program (SCP), Cognitive remediation treatment (CRT), High-intensity interval training (HIIT evening)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Central Institute of Mental Health, Mannheim
PTSD, Psychiatric Illness
Killing Pain - Use of Analgesic, Sedative and Anxiolytic Medication and the Development of Psychiatric Illness in Adolescents
Prescription of analgesic, sedative, and anxiolytic medication for children and adolescents is increasing in Western countries. In recent decades, rates have also increased in Norway, despite a relatively restrictive prescription…
- Conditions
- PTSD, Psychiatric Illness, Prescription Drug Dependence, Addiction
- Trial name
- NCT04336605
- Testing
- Age & Development, Socioeconomy, Traumatic Events
- Where
- Norway
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Pathological or "at Risk" Gambling
Transversal Multiaxial Evaluation and 5-year Follow-up of a Cohort of French Gamblers (JEU)
This study is divided into two stages. The first stage is a transversal study and corresponds to the recruitment of participants, which will last about two years.
- Trial name
- NCT01207674
- Testing
- Summons of patients and filling questionnaire
- Where
- 7 sites in France
- Volunteers
- 641 people
- Sponsor
- Nantes University Hospital
Smoking (Tobacco) Addiction
Addiction and Behavior Related to Menthol Cigarette Substitutes
The goal of the proposed study is to examine the abuse liability and substitutability of plausible menthol cigarette alternatives currently on the market, including menthol filtered little cigars (mFLC), menthol roll-your-own…
- Trial name
- MENTHOL (NCT04844762)
- Testing
- Menthol cigarettes substitutes, Usual brand menthol cigarettes and substitutes, Menthol cigarettes substitutes and menthol cigarettes
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Social Media Addiction
Roy Adaptation Model Based Strengthening Program and Social Media Addiction
In this pretest-posttest, randomized controlled study, the effect of the empowerment program developed based on Roy Adaptation on the healthy lifestyle behaviors, self-esteem and social media addiction of nursing students will be…
- Trial name
- NCT04820517
- Testing
- Roy Adaptation Model Based Strengthening Program
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Mersin University
Internet Gaming Disorder
Mental Imagery Tasks to Reduce Internet Gaming Disorder (IGD) Cravings
To test whether visual and auditory imagery tasks can effectively reduce the craving for IGD.
- Trial name
- NCT03868488
- Testing
- Imagery tasks
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jin-tao Zhang
Addictive Behavior, Substance-Related Disorders
Evaluation of the Efficacy of the Individually Adjusted Therapy Scale (ATI) on the Addiction Severity
The management of the craving is a key element in addiction treatment as the craving is linked to the probability of relapse. Several cues could induce the craving, some generic substance-induced cues or addictive…
- Trial name
- AjusT (NCT03606759)
- Testing
- Weekly assessment, Weekly assessment ajusted
- Where
- 4 sites in France
- Volunteers
- 151 people
- Sponsor
- University Hospital, Bordeaux
Obsessive-Compulsive Disorder, Autism Spectrum Disorder
ICBT for OCD in Children With Autism
The purpose of this trial is to evaluate the clinical efficacy, the cost-effectiveness and the effect durability of a therapist-guided, internet-delivered cognitive-behavior therapy intervention for obsessive-compulsive disorder…
- Trial name
- NCT06582225
- Testing
- Internet-delivered exposure and response prevention (I-ERP), Internet-delivered stress management (I-SM)
- Where
- 3 sites in Sweden
- Volunteers
- 220 people
- Sponsor
- Karolinska Institutet
Nicotine Use Disorder, Smoking Cessation
Implementation of Tobacco Cessation Programming at Community Behavioral Health Sites
The goal of this study is to: partner with Respiratory Health Association and determine barriers and unmet smoking cessation treatment needs from leaders in behavioral health organizations, treatment programs and adults who smoke…
- Conditions
- Nicotine Use Disorder, Smoking Cessation, Smoking Cessation Intervention
- Trial name
- NCT06837220
- Testing
- Enhanced Courage to Quit
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Chicago
Obsessive-Compulsive Disorder (OCD)
Impact of EsTOCma on OCD Family Members
The goal of this clinical trial is to test the acceptability, feasibility, and effectiveness of esTOCma in families and relatives of individuals with obsessive-compulsive disorder (OCD).
- Trial name
- esTOCma family (NCT06616350)
- Testing
- esTOCma: an app to fight stigma associated with OCD
- Where
- Spain
- Volunteers
- 211 people
- Sponsor
- University of Valencia