Clinical trials: Obsessive - Compulsive Disorder
Obsessive-Compulsive Disorder
Decision-making Impairments in OCD: An Integrated Behavioral Economics Model
The investigators are examining whether conditions of ambiguity during decision-making may prime intolerance of uncertainty beliefs (i.e., difficulties coping with ambiguity, unpredictability, and the future) and lead to impaired…
- Trial name
- NCT03420495
- Testing
- Decision-Making Tasks
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obsessive-Compulsive Disorder
Unique Electroencephalography (EEG) Markers of Habit Behaviors in Obsessive-Compulsive Disorder (OCD)
This study focuses on explaining the occurrence and development of compulsive behaviors from habit hypothesis. Investigators will study both OCD patients and healthy individuals using Hardwick's forced-response time task(2019)…
- Trial name
- NCT06882902
- Testing
- habit formation training
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Obsessive-compulsive Disorder
Electrophysiological Recording for Patients Receiving Deep Brain Stimulation Electrode for Treatment-resistant Obsessive-compulsive Disorder
The purpose of this project is to study live recordings from neuronal population of the human nucleus accumbens during the implantation of deep brain stimulation (DBS) electrodes for the treatment-resistant obsessive compulsive…
- Trial name
- NCT01429558
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Arizona
OCD, Major Depressive Disorder (MDD)
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
This is an observational study which does NOT directly administer a psychedelic substance but rather recruits participants who are already participating in another clinical trial in which they may receive a serotonergic…
- Conditions
- OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer
- Trial name
- NCT06624137
- Testing
- Serotonergic Psychedelic
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Yale University
Obsessive-Compulsive Disorder
Fear Conditioned Response in Healthy Subjects and in OCD Patients Pre and Post Treatment With Sertraline.
24 OCD patients and 24 healthy subjects will be submitted to a two-day fear conditioning paradigm during acquisition of functional magnetic resonance imaging (fMRI).
- Trial name
- FEARCON (NCT03068429)
- Testing
- Sertraline Hydrochloride
- Where
- Brazil
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Obsessive-Compulsive Disorder
Alternative Treatment to Reduce Chronicity in OCD: Research Into Brain Response and Adequacy of Treatment
Rationale: Obsessive-Compulsive Disorder (OCD) is a disabling neuropsychiatric disorder that often has a chronic disease course.
- Trial name
- arrIBA (NCT03929081)
- Testing
- Inference Based Approach (IBA), Cognitive Behavioural Therapy (CBT)
- Where
- 7 sites in Netherlands
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- GGZ Centraal
Obsessive-Compulsive Disorder
Reinforcement Learning and Obsessive-compulsive Disorder: Exploring the Role of the Orbitofrontal Cortex
Obsessive-compulsive disorder (OCD) is a neuropsychiatric condition affecting 1-3% of the population. Typically, symptoms start in adolescence or early adulthood, are time-consuming, and have a significant impact on quality of…
- Trial name
- NEUROCOMP (NCT06566781)
- Where
- Portugal
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Fundacao Champalimaud
Obsessive Compulsive Disorder
Overlapping Neural Circuits in Pediatric OCD
The purpose of this study is to examine the brain functioning of children and adolescent with OCD before and after treatment with Exposure and Response Prevention (EXRP) therapy.
- Trial name
- NCT02421315
- Testing
- CBT treatment for OCD based on Exposure & Response Prevention (EX/RP) and when indicated medication treatment
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Obsessive-Compulsive Disorder
Study on the Efficacy Mechanism of Natural Psychotherapy for Neurosis
explore objective indicators of the efficacy of natural psychotherapy in the treatment of disorders such as obsessive-compulsive disorder
- Trial name
- NCT05552014
- Testing
- Natural Psychotherapy, waitlist control group
- Where
- 2 sites in China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Beijing HuiLongGuan Hospital
Obsessive Compulsive Disorder
Neurobiology of Sensory Phenomena in Obsessive-Compulsive Disorder
The Research Domain Criteria (RDoC) approach seeks to address the neurobiological mechanisms of sensory symptoms in patients with obsessive-compulsive disorder (OCD) by investigating dimensional components of behavior that more…
- Trial name
- NCT03451409
- Testing
- Tasked based functional MRI (fMRI), Eye Tracking Device
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Anorexia Nervosa, Obsessive-compulsive Disorder
Neural Links Between OCD and Anorexia
Individuals with anorexia nervosa (AN) have long been observed to demonstrate symptoms in common with obsessive-compulsive disorder (OCD), in particular, an obsessive fear of normal weight leading to dangerous food restriction…
- Trial name
- NCT02085057
- Testing
- Functional Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Stanford University
Anorexia Nervosa, Obsessive-Compulsive Disorder
Radical Openness for Adolescents Pilot
Heightened performance monitoring and overcontrol (HPM/OC) is characterized by inflexibility, a need for control, perfectionism, anxious apprehension and high error monitoring.
- Conditions
- Anorexia Nervosa, Obsessive-Compulsive Disorder, Social Phobia, Depression, Anxiety
- Trial name
- ROA (NCT05913557)
- Testing
- Radically Open Dialectical Behavior Therapy (RO DBT)
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obsessive-Compulsive Disorder
Exposure and Response Prevention With Behavioral- Versus Cognitive Therapy Rationale in Obsessive Compulsive Disorder
The aim of the study is to determine whether exposure and response prevention (ERP) is more effective when patients are presented with a behavioral therapy versus cognitive therapy rationale in the treatment of…
- Trial name
- NCT00184262
- Testing
- ERP cognitive therapy, ERP behavioral therapy
- Where
- Norway
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Obsessive-Compulsive Disorder, Cognitive Behavioral Therapy
Brief Culturally Adapted CBT for OCD
The purpose aims to assess the efficacy of Brief Culturally Adapted Cognitive Behaviour Therapy (Ca-CBT) for the treatment of Obsessive Compulsive Disorder (OCD).
- Trial name
- NCT07232823
- Testing
- Brief culturally adapted cognitive behaviour therapy (CaCBT)
- Where
- Pakistan
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Pakistan Association of Cognitive Therapists
Autism, Asperger's Syndrome
Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
Autism spectrum disorders affect as many as 1 out of 150 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Generalized Anxiety Disorder, Social Phobia
- Trial name
- NCT01178385
- Testing
- Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Obsessive Compulsive Disorder OCD
Impact of Attention on Obsessive Thoughts Through THOUGHT
Impact of attention on obsessive through the THOUGHT-scale (Troublesome Human Obsessions and Untargeted General Habitual Thoughts Scale): a description of the content of thoughts according to the level of attention demanded by…
- Trial name
- THOUGHTS (NCT05944172)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obsessive Compulsive Disorder
Cost-Effectiveness of Adding Web-Based Cognitive-Behavioral Therapy (CBT) to Luvox CR for Obsessive Compulsive Disorder (OCD)
This study will test the hypotheses that: 1. 12 weeks of Luvox-CR plus web-based Cognitive-Behavioral Therapy (CBT) [CT-STEPS] will produce greater symptom relief of OCD than treatment with Luvox-CR alone; and, 2.
- Trial name
- NCT00743834
- Testing
- Luvox CR, Behavioral Therapy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rogers Center for Research & Training, Inc.
Major Depressive Disorder, Obsessive-Compulsive Disorder
Bioequivalence Study of Paroxetine Tablets and Paxil® Under Fasting and Fed Conditions in Chinese Healthy Volunteers
The objective of this study is to compare the rate and extent of absorption of paroxetine hydrochloride 20 mg tablets (test) and Paxil® (reference) administered as 20 mg tablet under fed conditions.
- Conditions
- Major Depressive Disorder, Obsessive-Compulsive Disorder, Panic Disorder, Social Anxiety Disorder
- Trial name
- NCT03504475
- Testing
- Paroxetine Hydrochloride Tablet 20 mg, Paxil® 20 mg
- Where
- 2 sites in China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Obsessive-Compulsive Disorder, Anxiety Disorders
Efficacy of Exposure and Response Prevention(ERP) and SSRIs in Chinese OCD Patients
The purpose of this study is to evaluate the efficiency of SSRIs（Selective Serotonin Reuptake Inhibitor） ,ERP（Exposure and Response Prevention） and the combination of the two therapies for OCD(Obsessive-Compulsive Disorder)…
- Conditions
- Obsessive-Compulsive Disorder, Anxiety Disorders, Mental Disorders
- Trial name
- NCT02022709
- Testing
- Fluoxetine, Sertraline, Paroxetine
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
OBSESSIVE COMPULSIVE DISORDER (OCD)
The Efficacy of TBCT Compared to ERP in the Treatment of OCD Patients, by the Assessment of Magnetic Resonance.
This is a sample made up of ninety-six adult individuals of both sexes to be divided into three groups: the experimental group of thirty-two patients with OCD who will be undergone Trial-Based Cognitive Therapy; the gold…
- Trial name
- NCT02656784
- Testing
- Cognitive Therapy, Behavioral Therapy
- Where
- Brazil
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do PiauÍ