Clinical trials: Obesity in Adolescents
Obesity
Think AHEAD (A Healthy Eating And Drinking) Study
Advice to increase water consumption as part of a weight-reducing diet - typically to 8 cups (64 fl oz, ~2 L) per day ("8x8" water recommendation) - is almost ubiquitously recommended by healthcare professionals.
- Trial name
- NCT01044134
- Testing
- Dietary counseling
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Obesity, Childhood, Obesity, Adolescent
PROBESITY-2: Synbiotics in Pediatric Obesity
The global obesity epidemic presents an unprecedented challenge to the public health worldwide. The factors associated with obesity are complex, and include health behaviours, such as eating habits and daily physical activity…
- Trial name
- PROBESITY-2 (NCT05162209)
- Testing
- Synbiotic
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Obesity, Adolescent
Myokines Role During Obesity
We showed, for the first time, that Z-score increase during obesity was dependent on sex, severity of obesity and age but also on the bone site.
- Trial name
- Bonamy (NCT02973867)
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Overweight Adolescents, Obesity, Adolescent
Effects of the Daily Mile Program on General Health in Overweight/Obese Schoolchildren
This study is a clinical trial will be carried out during academic term to assess the potential effects of the Daily Mile program on health-related physical fitness and sleep quality on overweight/obese schoolchildren.The trial…
- Trial name
- NCT05862506
- Testing
- Daily Mile
- Where
- Colombia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Unidades Tecnológicas de Santander
Childhood Obesity
Nutrition and Physical Activity Counselling
Background: Childhood obesity imposes a great burden on the healthcare system. Given the increased frequency of dental compared to medical visits during childhood, dentists may be in an ideal position to recognize patients at…
- Trial name
- NCT02637752
- Testing
- Lifestyle counseling or nutrition/physical counselling
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity, Insulin Resistance
Vitamin K to Slow Progression of Dyslipidemia and Diabetes Risk (Vita-K 'n' Kids Study II)
Animal studies have found that vitamin K-dependent proteins matrix Gla protein and osteocalcin beneficially influence lipid and glucose metabolism, respectively.
- Conditions
- Obesity, Insulin Resistance, Obesity in Diabetes, Nutritional and Metabolic Diseases
- Trial name
- NCT02959762
- Testing
- Low-Dose Vitamin K2 (menaquinone-7; 45-mcg/d), High-Dose Vitamin K2 (menaquinone-7; 90 mcg/d)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Augusta University
Obesity, Type 2 Diabetes
Activity and Metformin Intervention in Obese Adolescents
The purpose of this study is to assess the sustainability of a two-year intervention aimed at improving body mass index (BMI) and metabolic and vascular health in obese youth.
- Trial name
- REACH (NCT00934570)
- Testing
- Metformin and standard exercise, Metformin Intensive exercise, Intensive exercise
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Obesity, Cardiovascular Risk
School Based Health Promotion Program in Secondary Schools
The purpose of the study is to determine whether a school based health promotion program in secondary schools is effective with respect to an increase of physical activity, physical fitness and health.
- Trial name
- JuvenTUM 3 (NCT00988754)
- Testing
- School children and adolescents as health experts
- Where
- Germany
- Volunteers
- 595 people
- Sponsor
- Technical University of Munich
Body Weight, Nutrition Processes
Effectiveness Evaluation of Three Strategies of Promotion of Healthy Dietary and Physical Activity Behaviours to Prevent Weight Excess Among Teenagers
The aim of this study is to compare the effectiveness of three public health intervention strategies to reduce weight excess and obesity prevalence among teenagers within the frame of a public health program aiming at promoting…
- Conditions
- Body Weight, Nutrition Processes, Prevention
- Trial name
- PRALIMAP (NCT00814554)
- Testing
- Educational strategy, Screening strategy, Environmental strategy
- Where
- France
- Volunteers
- 5,458 people
- Sponsor
- University of Nancy
Polycystic Ovary Syndrome
Insulin Resistance, Polycystic Ovary Syndrome, and Bone Research Study
The purpose is to investigate the effects of 2 different treatments (drospirenone/ethinyl estradiol versus rosiglitazone) on insulin sensitivity and androgen levels, inflammatory markers, vascular markers and bone development in…
- Trial name
- NCT00640224
- Testing
- rosiglitazone, drospirenone/ethinyl estradiol
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Silva Arslanian
Adolescent Obesity
Antrum Size, Glucagon-like Peptide 1 Levels and Glycemic Control After Sleeve Gastrectomy in Morbid Obese Diabetic Adolescents
Childhood obesity can adversely affect every organ and often has serious consequences. Compare the effect of transection at 2cm vs at 5cm from the pylorus during laparoscopic sleeve gastrectomy on the postoperative weight loss…
- Trial name
- NCT04388059
- Testing
- Laparoscopic sleeve gastrectomy
- Volunteers
- 18 people
- Sponsor
- Tanta University
Obesity, Surgery
Effects of Weight Loss Surgery on Bone Health in Adolescents
The purpose of this study is to examine the impact of weight-loss surgery (Roux-en-Y gastric bypass or Vertical Sleeve Gastrectomy) on bone outcomes in girls and boys ages 13-21.
- Trial name
- NCT02557438
- Testing
- Roux-en-Y Gastric Bypass, Vertical Sleeve Gastrectomy
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Massachusetts General Hospital
Metabolic Syndrome
Examining the Relationship Between Tobacco Exposure, Abdominal Obesity, and Metabolic Syndrome in Adolescents (The STRONG Kids Study)
Metabolic syndrome is a term that describes a group of conditions that increase the risk of cardiovascular disease. The conditions include high blood pressure, obesity, and high cholesterol.
- Trial name
- STRONG Kids (NCT00808158)
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Obesity
Adipokines in Obese Adolescents With Insulin Resistance
The purpose of this study is to compare serum concentrations of inflammatory cytokines, interleukin 6 (IL-6), High-sensitivity C-reactive protein (hs-CRP), adiponectin, and tumour necrosis factor alpha (TNFα), before and after…
- Trial name
- NCT01410604
- Testing
- Metformin
- Where
- 2 sites in Mexico
- Volunteers
- 31 people
- Sponsor
- Hospital Regional de Alta Especialidad del Bajio
Hypertension, Retinal Artery Stenosis
Exercise, Arterial Modulation and Nutrition in Youth South Africa Study
The ExAMIN Youth SA study aims to generate new knowledge on the pathophysiology involved in early vascular aging among South African children and to identify early novel biological markers for predicting the subclinical…
- Conditions
- Hypertension, Retinal Artery Stenosis, Childhood Obesity
- Trial name
- ExAMIN-Youth (NCT04056377)
- Where
- South Africa
- Volunteers
- 1,065 people, healthy volunteers welcome
- Sponsor
- North-West University, South Africa
Dairy Consumption, Metabolic Health
The Effect of Dairy Intake on Body Weight and Composition and Metabolic Health in Adolescents and Seniors
The goal of this study is to examine how regular dairy intake affects body weight, body composition, and metabolic health in overweight and obese adolescents (ages 15-18) and older adults (ages 60-80) over six months.
- Conditions
- Dairy Consumption, Metabolic Health, Obesity Prevention
- Trial name
- NCT06879652
- Testing
- Counselling to follow Canada's Food Guide and 3 daily servings of Dairy (long-term study), Dairy (short-term study), Counselling to follow Canada's Food Guide (long-term study)
- Where
- 2 sites in Canada
- Volunteers
- 240 people
- Sponsor
- University of Toronto
Obesity & Overweight, Pediatric Obesity
Ultrasound Assessment of Tongue Characteristics in Children and Adolescents With Obesity
This longitudinal observational study aims to validate ultrasound-based tongue markers related to tongue characteristics, including fat accumulation, morphologic and mechanical properties of the tongue in children and adolescents…
- Conditions
- Obesity & Overweight, Pediatric Obesity, Obstructive Sleep Apnea (OSA)
- Trial name
- NCT07370350
- Testing
- Submental ultrasound
- Where
- 2 sites in Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Haute Ecole Bruxelles-Brabant
Metabolic Dysfunction-Associated Steatotic Liver Disease, Childhood Obesity
Lifestyle Habits and Metabolic Dysfunction-Associated Steatotic Liver Disease in Youth
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is the most common cause of chronic liver disease in children and adolescents.
- Trial name
- LIFE4MASLD (NCT07095010)
- Where
- Greece
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Obesity
"Generation Fit and Exerlearning With In the Groove"
In middle schools participating in a statewide program called "Take Time", we are randomizing youth to a 10-12 week intervention using the dance mat games on the Playstation2 (like Dance Dance Revolution).
- Trial name
- NCT00424918
- Testing
- Physical Activity, reduced sedentary behavior
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- MaineHealth
Obesity, Children
Polygenic Risk Score to Predict Weight Loss Intervention in Children With Obesity
Children with obesity are prone to suffering from metabolic diseases, which undoubtedly increases the burden of public health. Since obesity is a multiple gene disease, a comprehensive approach using polygenic risk scores (PRS)…
- Trial name
- NCT05466097
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Far Eastern Memorial Hospital