Clinical trials: Obesity (Disorder)
Obesity, Obesity, Childhood
Parent-Based Intervention Following a Weight Loss Surgery
Prevention and early intervention are the most effective methods for influencing eating habits. This study helps fulfill the Department of Psychiatry's missions of clinical innovation and advancing science.
- Trial name
- PBP-B (NCT04247113)
- Testing
- Parent-based prevention following bariatric surgery
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Stanford University
Diabete Type 2, Abdominal Obesity
Translational Study Using Human Abdominal Adipose Tissue Biopsies to Investigate the Role of Cannabinoid Receptor 1 (CB1) in Controlling Endocannabinoid and Adipokine Secretion
Abdominal obesity and type 2 diabetes are associated with the hyperactivation of the endocannabinoid system. Several animal and human studies indicate that circulating endocannabinoid (EC) levels are correlated with body fat.
- Trial name
- ENDOCATA (NCT04940962)
- Testing
- Sampling of adipose tissue
- Where
- France
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Obesity, Neuraxial Ultrasound
Neuraxial Anaesthesia: Does BMI Relate to Ease of Neuraxial Anaesthesia?
Neuraxial anaesthesia can be more difficult and associated with more complications if the patient's bony landmarks are difficult to palpate.
- Conditions
- Obesity, Neuraxial Ultrasound, Obstetric Anaesthesia
- Trial name
- NCT03315845
- Testing
- Palpation of bony landmarks for neuraxial anaesthesia.
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Maternity Hospital, Ireland
Bariatric Surgery, Lipidemia
the Related Factors of Bariatric Surgery on Lipidemia
Obesity and related metabolic diseases have become a chronic disease that is a threat to human health. Bariatric surgery can effectively and long-term reduce excess body weight and relieve related metabolic diseases, including…
- Trial name
- NCT03689803
- Testing
- sleeve gastrectomy, gastric bypass
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Jinan University
Childhood Obesity
Substrate Oxidation in Children in Response to High and Low Dairy Intake
The investigators propose a randomized trial comparing higher levels of dairy intake compared to lower levels of dairy intake. Participants will be 20 boys and girls, age 10-13, overweight (>85%) who are currently consuming 1 or…
- Trial name
- NCT01664702
- Testing
- Dairy Products, Dairy Servings
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Obesity
Muscle Lipid and Insulin Resistance in the Elderly
This project will provide novel information concerning the ability of exercise to enhance the capacity for oxidative metabolism of fatty acids and improve insulin resistance in older adults who are at high risk for the…
- Trial name
- MIRA (NCT00765505)
- Testing
- Exercise Group, Health Education Group
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obesity & Overweight, Infertility, Female
Dietary Reversal of the Reprometabolic Syndrome
This study proposes to test the specific question that a eucaloric, low-fat diet given to women with obesity will result in an increase in reproductive hormones.
- Trial name
- LFD (NCT07227766)
- Testing
- Low-fat diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Host and Microbiome, Pregnancy Outcomes
Human Genes and Microbiota in Early Life
The long-term goal of the Human Genes and Microbiota in Early Life (HuGME) is to explore the short- and long-term effects of maternal microbiota during pregnancy and the microbiota colonization of their offspring early in life…
- Conditions
- Host and Microbiome, Pregnancy Outcomes, Pregnancy Complications, Neurodevelopmental Disorders
- Trial name
- HuGME (NCT06926166)
- Testing
- No intervention
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Obesity
Defining the Role of the Gut Microbiome in Mediating the Effects of Obesity on Intestinal Stem Cells
New studies are revealing how a high-fat diet could be making the cells of the intestinal lining more likely to become cancerous.
- Trial name
- NCT02863029
- Testing
- Flexible Sigmoidoscopy
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Overweight and Obesity
A Phase 1, Double-blind, Randomized Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of Single Dose and Multiple Doses of CG-0416 in Healthy Participants.
A Phase 1, double-blind, randomized study to evaluate the safety, tolerability, pharmacodynamics, and pharmacokinetics of single dose and multiple doses of CG-0416 in healthy participants. HongKong Curegene Innovation Co.
- Trial name
- NCT07724431
- Testing
- CG-0416
- Where
- Australia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- HongKong Curegene Innovation Co., Limited
Obesity and Obesity-related Medical Conditions
A Study of MET233 in Combination With MET097 in Individuals With Obesity or Overweight With or Without Diabetes
This study is designed to test how well the combination of MET233 with MET097 works to treat individuals with obesity or overweight with or without diabetes.
- Trial name
- NCT06924320
- Testing
- MET233 and MET097, MET097
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Pfizer
Prediabetes
Effects of Coffee Consumption on Metabolic Markers in Adults With Prediabetes and Obesity
Epidemiological studies have shown an inverse association between coffee consumption and risk of type 2 diabetes. However, the randomized controlled trials in prediabetes are limited to evaluate the effects of coffee.
- Trial name
- NCT06330727
- Testing
- Coffee capsule, Corn starch capsule
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Obesity, Appetitive Behavior
Pre- and Post-prandial Levels of Appetite Regulatory Hormones in Adults
The present study aims to evaluate in adults with normal weight and with overweight or obesity who live in the city of La Plata the circulating levels of various hormones that regulate appetite and the gene expression of their…
- Trial name
- NCT05815641
- Testing
- food (breakfast)
- Where
- Argentina
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Instituto de Desarrollo e Investigaciones Pediátricas Prof. Dr. Fernando E. Viteri
Obesity, Overweight
Comparing Effect of Short Sleep Duration on Weight Loss of Overweight and Obese Women Attending a Weight Loss Program
The purpose of the present study is to evaluate the effect of sleep duration on weight loss of obese and overweight adult when they are in a weight loss plan (NovinDiet Protocol).
- Trial name
- NCT03120260
- Testing
- Diet
- Where
- Iran
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Novindiet Clinic
Energy Expenditure, Body Composition
The Energy Cost of 1-Hour Football Training
This study aims at investigating the energy expenditure following a single Football trainning session in middle aged males. The participants will perform a soccer training session [A single training session including 60 minutes…
- Conditions
- Energy Expenditure, Body Composition, Resting Metabolic Rate, Overweight and Obesity
- Trial name
- FAM (NCT06477705)
- Testing
- FAM
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Mood, Stress
Walking Green: The Effects of Walking in Forested and Urban Areas
This research hypothesizes that moderate physical activity in a "green environment" (e.g. a forest preserve path) has increased benefits on psychological measures (stress, anxiety, mood, depression, attention) and on…
- Conditions
- Mood, Stress, Anxiety, Depression
- Trial name
- NUWG (NCT03950661)
- Testing
- Walking
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Overweight, Obesity
Mitochondrial Methylation in Type 2 Diabetes
The overarching goal of this proposal is to determine whether DNA methylation of the mitochondrial DNA impairs mitochondrial function in insulin resistant states such as overweight/obesity and type 2 diabetes.
- Conditions
- Overweight, Obesity, Diabetes Mellitus, Type 2, Insulin Resistance
- Trial name
- NCT04126551
- Testing
- Methylation status
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Obesity, Overweight
Nutrition and Soccer for Pediatric Overweight and Obesity
This study will examine whether two months of youth soccer, combined with a single brief behavioral/nutritional intervention, can reduce BMI in 5th grade overweight or obese females.
- Trial name
- NCT00365651
- Testing
- Youth Soccer
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Leach Chiropractic Clinic
Polycystic Ovary Syndrome
Mediterranean Diet Versus Hypocaloric Diet in PCOS
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy of reproductive-aged women that manifests itself with chronic anovulation, hyperandrogenism and insulin resistance.
- Trial name
- NCT02397174
- Testing
- mediterranean diet, restricted calorie, hypocaloric diet, restricted calorie
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera OO.RR. S. Giovanni di Dio e Ruggi D'Aragona
Obesity, Diabetes Mellitus
Type 2 Diabetes Primary Prevention for At Risk Girls
Purpose: To evaluate two approaches to prevent obesity and type 2 diabetes in young girls. The Need: We are experiencing an epidemic of childhood obesity.
- Conditions
- Obesity, Diabetes Mellitus, Pre Diabetes
- Trial name
- NCT00063674
- Testing
- Nutrition Education, After-school dance class
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
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