Clinical trials: Obesity, pill or tablet or capsule or oral
Type 2 Diabetes Mellitus, Insulin Resistance
Anti-Inflammatory Small Drug Adjunctive Therapy for Type 2 Diabetes
The role of individual leukocyte populations in type 2 diabetes (T2D) and immunometabolism in general represent important gaps in knowledge to better understand the etiopathogenesis of T2D.
- Trial name
- NCT02597101
- Testing
- Metformin, saxagliptin, AZD9668
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Nick Giannoukakis, PhD
Obesity and Type 2 Diabetes
BMS-646256 in Obese and Overweight Type 2 Diabetics
This is a placebo-controlled, randomized, double-blind, parallel arm, multicenter, dose-ranging phase IIb trial to assess glycemic and weight loss efficacy and safety of BMS-646256 in overweight and obese patients with type 2…
- Trial name
- NCT00541567
- Testing
- ibipinabant
- Volunteers
- 600 people
- Sponsor
- Solvay Pharmaceuticals
PreDiabetes, Blood Glucose, High
Investigation of Cinnamon Spice on Glucose Tolerance in Subjects With Pre-diabetes
This study aims to determine whether the effectiveness of cinnamon spice capsules vs. placebo capsules on glucose tolerance in prediabetic subjects who are overweight or obese.
- Trial name
- CINNII (NCT04342624)
- Testing
- Cinnamon
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Obesity and Cardiovascular Risk
A Phase 2 Study to Evaluate the Pharmacodynamics, Safety and Tolerability of BGE-102 in Participants With Obesity and Cardiovascular Risk Factors
The purpose of this study is to learn about the effects of BGE-102 on blood biomarkers including hsCRP, which is a lab value used to measure inflammation.
- Trial name
- QUELL-CV (NCT07656727)
- Testing
- Oral BGE-102
- Where
- 17 sites in United States, Puerto Rico
- Volunteers
- 160 people
- Sponsor
- BioAge Labs, Inc.
Obesity, Prediabetic State
The Study Aims to Investigate the Effects of Oral Inositols on Insulin-resistance in Children With Obesity.
The study aims to investigate the effects of oral inositols on insulin-resistance and metabolic variables (triglycerides, total cholesterol, HDL cholesterol) in children aged 8-12 years with obesity and insulin-resistance.
- Conditions
- Obesity, Prediabetic State, Dyslipidemias, Insulin Resistance
- Trial name
- ONIRICO (NCT05701813)
- Testing
- INOSITOLS, CELLULOSE
- Volunteers
- 56 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Obesity & Overweight
Xanthigen and Its Impact on Weight and Metabolic Health
Randomized, controlled, triple-blind clinical trial with three parallel arms based on the product consumed (low-dose experimental product, high-dose experimental product, and placebo product) and conducted at a single center to…
- Trial name
- XAN (NCT07519980)
- Testing
- Experimental group: Xanthigen®, Control product
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Bariatric Surgery Candidate, Dysbiosis
The Effect of Probiotics on Systemic Inflammation and Metabolic Endotoxemia in Patients Undergoing Bariatric Surgery
This study explores the effects of probiotic administration on the outcomes of surgical treatment, and also on the state of the intestinal microbiota and the intestinal barrier.
- Trial name
- NCT05407090
- Testing
- probiotic supplementation
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Medical University of Gdansk
Asymptomatic Conditions
Effects of Caffeine and Coffee on Resting Metabolic Rate, Comparing Normal Weight Men to Obese Men
Background. The prevalence of obesity has increased in the last two decades. To maintain body weight energy expenditure (EE) should be equal to energy intake (EI).
- Trial name
- RMR (NCT02751840)
- Testing
- Caffeine, Coffee, Decaffeinated
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
Hypothalamic Obesity, Hypothalamic Tumor
Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity
Hypothalamic obesity (HO) refers to the substantial weight gain that often complicates hypothalamic brain tumors. Children with this treatment-recalcitrant form of obesity have excess rates of metabolic sequelae compared to…
- Conditions
- Hypothalamic Obesity, Hypothalamic Tumor, Craniopharyngioma
- Trial name
- NCT06299891
- Testing
- Phentermine / Topiramate Extended Release Oral Capsule [Qsymia]
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Seattle Children's Hospital
Satiety, Appetite
A Study of NatureU Burn on Satiety in Healthy Adults
This single-center, single-blind, non-randomized crossover exploratory study evaluated the short-term effects of NatureU Burn on postprandial satiety in healthy adults.
- Conditions
- Satiety, Appetite, Food Intake, Fat Disorder
- Trial name
- NUBURN (NCT07597382)
- Testing
- Glucose Reference Food, NatureU Burn Plus Glucose
- Where
- China
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- OmniSolutions Laboratory Holdings Limited
Overweight and Obesity
Evaluation of Obex® in Overweight and Obesity
Obesity is an important and growing worldwide Obesity is highly related to the development of metabolic syndrome, diabetes, cardiovascular diseases and cancer Diverse adverse events have been reported with the use of antiobesity…
- Trial name
- NCT03541005
- Testing
- Obex
- Where
- Cuba
- Volunteers
- 160 people
- Sponsor
- Catalysis SL
Obesity, Binge Eating
Treatment of Obesity and Binge Eating: Behavioral Weight Loss Versus Stepped Care
This controlled study will test the effectiveness of a stepped-care approach to a standard behavioral weight loss treatment for obese patients with Binge Eating Disorder (BED).
- Trial name
- NCT00829283
- Testing
- Behavioral Weight Loss, Behavioral Weight Loss + Guided self-help Cognitive-behavioral Therapy, Sibutramine/Orlistat
- Where
- United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- Yale University
Overweight, Obesity
Effects of Obex in Overweight and Obese Patients
Obesity is an important and growing public health worldwide Obesity is highly related to the development of metabolic syndrome, diabetes, cardiovascular diseases and cancer An extensive body of evidence from efficacy trials has…
- Trial name
- NCT02145442
- Testing
- Obex
- Where
- Cuba
- Volunteers
- 40 people
- Sponsor
- Catalysis SL
Schizophrenia, Insulin Resistance
Salsalate for Insulin Resistance in Schizophrenia
Being obese is a common problem for people with schizophrenia. People with schizophrenia are more likely to be overweight compared to the general population.
- Trial name
- NCT01182727
- Testing
- salsalate
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- University of Maryland, Baltimore
Pregnancy, Obesity
Effect of Probiotics (Vivomixx®) on Weight, Microbiota and Glucose Tolerance in Obese Pregnant Women and Their Newborn
The purpose of the study is to investigate if the probiotics Vivomixx® can affect gestational weight gain, microbiota and pregnancy complications in pregnant obese women and birth weight body composition of their infants.
- Conditions
- Pregnancy, Obesity, Gestational Diabetes Mellitus
- Trial name
- POP (NCT02508844)
- Testing
- Vivomixx®
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Overweight and Obesity, Lupus Erythematosus
Methyl-donor Nutrient Supplementation and Methylation Profile in Lupus Patients With Obesity
Dietary supplementation with methyl donors has been demonstrated to increase DNA methylation in leucocytes whereas a limited dietary intake of methyl donors was associated with DNA hypomethylation.
- Trial name
- NCT05097365
- Testing
- Vitamin B12 + folic acid supplementation
- Where
- Brazil
- Volunteers
- 51 people
- Sponsor
- University of Sao Paulo
Obesity
Dose-ranging Study of SKF7™ for Obesity
This study has been designed as a randomized, double blinded, multi-centric, placebo controlled, and phase II dose-ranging study.
- Trial name
- NCT04557267
- Testing
- low-dose, Middle-dose, Higher-dose
- Where
- 3 sites in Indonesia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Obesity
A Study to Evaluate the Safety, Tolerability, and Weight Loss Efficacy of K-757 Alone and in Combination With K-833
This is a study to evaluate the safety and efficacy of K-757 alone and in combination with K-833 versus placebo in participants who are obese.
- Trial name
- NCT06019559
- Testing
- K-757 120 mg BID and K-833 100 mg BID
- Where
- 22 sites in United States
- Volunteers
- 155 people
- Sponsor
- TriGemX Bio, Inc.
Obesity
Thermogenic Properties of Zantrex-3
Background: Zantrex-3® is a popular dietary supplement for weight control, which consists of a combination of yerba mate, guarana, caffeine and damiana.
- Trial name
- ZANTREX (NCT01622101)
- Testing
- Thermogenic properties of Zantrex-3®
- Where
- Denmark
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Obesity
Longitudinal Assessment of Cardiovascular and Metabolic Parameters in Obese and Lean Children
The investigators hypothesize that cardiovascular and metabolic alterations due to obesity already manifest at childhood age. To identify these alterations and risk factors, the investigators have established a cohort of 177…
- Trial name
- NCT01605123
- Where
- 2 sites in Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
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