Clinical trials: Obesity, diet or lifestyle or exercise or nutrition or physical activity or counseling, open to volunteers
- Condition Obesity
- Drug or intervention diet OR lifestyle OR exercise OR nutrition OR physical activity OR counseling
- Status Open to volunteers
Physical Inactivity, Overweight
Individual Variability in Energy Compensation After a 12-Week Supervised Exercise Intervention
This prospective, single-arm interventional study will investigate why adults receiving the same prescribed dose and relative intensity of exercise show divergent changes in energy balance, body weight, and body composition.
- Conditions
- Physical Inactivity, Overweight, Obesity
- Trial name
- NCT07893249
- Testing
- Supervised Aerobic Exercise Programme
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Liver Cirrhoses, Portal Hypertension Related to Cirrhosis
Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease
Cirrhosis is a form of advanced liver disease that can lead to serious complications, especially when combined with severe obesity.
- Conditions
- Liver Cirrhoses, Portal Hypertension Related to Cirrhosis, Severe Obesity, TIPS
- Trial name
- OPTIMAL (NCT07058155)
- Testing
- Transjugular Intrahepatic Portosystemic Shunt (TIPS), Sleeve Gastrectomy, Anti-Obesity Pharmacotherapy (Class Effect)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The Cleveland Clinic
Obesity, Weight Control
ASCEND-1: Lifestyle Intervention Plus Mazdutide for Weight Management
Obesity is a chronic, progressive, and relapsing disease. Although lifestyle interventions and anti-obesity medications are effective for inducing weight loss, evidence regarding their role in long-term weight maintenance after…
- Trial name
- NCT07517042
- Testing
- Mazdutide, Intensive Lifestyle Intervention, Usual Lifestyle Counseling
- Where
- 13 sites in China
- Volunteers
- 420 people
- Sponsor
- Shanghai Zhongshan Hospital
Obesity
Weight Loss Through Mayo Clinic Diet
The purpose of study is to evaluate the efficacy of the Mayo Clinic Diet in clinically significant weight loss (>5%) versus usual care.
- Trial name
- NCT06862375
- Testing
- Mayo Clinic Diet, Usual Care
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obesity & Overweight
Multimodal Intervention for Weight Management and Health in the Elderly Population
Aging may be accompanied by changes in body composition, muscle strength, metabolic health, and well-being. In older adults with overweight or obesity, strategies that combine physical exercise, behavioral changes, and…
- Trial name
- NCT07820774
- Testing
- Nutritional guidance focused on adopting a high-protein diet., Group Cognitive Behavioral Therapy Intervention, Resistance Training Program
- Where
- Brazil
- Volunteers
- 54 people
- Sponsor
- Universidade Cesumar (UNICESUMAR)
Diabete Type 2, Obesity & Overweight
Nutrition Intervention Optimization to Better Utilize Resources and Support Health
Not having enough food for each person in a household, also called food insecurity, makes it hard to eat a nutritious diet, maintain a healthy weight, and manage diabetes risk.
- Conditions
- Diabete Type 2, Obesity & Overweight, Nutritional Intervention, Food Insecurity
- Trial name
- NOURISH (NCT07713836)
- Testing
- Meal kits, No-prep meals, Culinary nutrition classes
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Tufts University
Obesity (BMI Equal to or >30), Postmenopausal Symptoms
Time-Restricted Eating and Personalized Energy-Restricted Diet in Obese Postmenopausal Women
This clinical study aims to compare the effects of time-restricted eating and a personalized energy-restricted diet on anthropometric measurements, body composition, biochemical parameters, blood pressure, handgrip strength…
- Conditions
- Obesity (BMI Equal to or >30), Postmenopausal Symptoms, Sleep Quality
- Trial name
- NCT07874399
- Testing
- Time-Restricted Eating, Personalized Energy-Restricted Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gazi University
Hypertension, Dyslipidemia
A Novel Digital Tool Clinicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors
The investigators will conduct a feasibility and pilot efficacy randomized controlled trial to test the usability and user satisfaction of an evidence-based digital health tool the investigators developed for clinicians to use to…
- Conditions
- Hypertension, Dyslipidemia, Diabetes Mellitus, Obesity
- Trial name
- P3-EX (NCT07238556)
- Testing
- Experimental - 12 Week P3-EX Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants, Active Control - 12 Week ACSM-PAVS Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants
- Where
- 3 sites in United States
- Volunteers
- 72 people
- Sponsor
- University of Connecticut
PCOS (Polycystic Ovary Syndrome), Insulin Resistance
Inositol and Metformin Administration in Mediterranean Diet and Low-Carbohydrate Diets in Women With PCOS
Polycystic ovary syndrome (PCOS) is a common endocrine disorder frequently associated with obesity, insulin resistance (IR), and metabolic dysfunction.
- Conditions
- PCOS (Polycystic Ovary Syndrome), Insulin Resistance, Obesity (BMI>30)
- Trial name
- NCT07770711
- Testing
- Metformin, İnositol, Folic Acid
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dicle University
Normal-weight Obesity
The Interaction of Body Composition, Sex Hormones and Exercise in Men
The overall objective of this project is to advance understanding of the causes of normal weight obesity (NWO) in men, namely the hormone profile and related potential mediating mechanisms, and the efficacy of different modes of…
- Trial name
- AHA-NWO (NCT06970457)
- Testing
- Resistance Exercise Training, Aerobic Exercise Training
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Type2diabetes, Heart Failure
Understanding and Addressing Risks of Low Socioeconomic Status and Diabetes for Heart Failure
This study aims to determine whether a 6-month multilevel intervention involving problem-solving training, exercise training and support from community health workers is more effective in improving outcomes for individuals with…
- Conditions
- Type2diabetes, Heart Failure, Obesity
- Trial name
- UNLOAD-HF (NCT06364644)
- Testing
- Community Champions, Homegrown Heroes
- Where
- 2 sites in United States
- Volunteers
- 156 people
- Sponsor
- Johns Hopkins University
Obesity
Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments
Background Obesity and physical inactivity contribute substantially to cardiovascular disease risk, diabetes, hypertension, and dyslipidemia.
- Trial name
- NCT03288207
- Testing
- AMRA(r) Researcher Image reconstruction software, MRI: radiofrequency coils (Device Manufacturer: Siemens Medical Solutions USA, Inc.), MRI: Research pulse sequences (Device Manufacturer: NIH)
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Bariatric Surgery and Physical Activity, Obesity/Therapy
Impact of a Perioperative Physical Exercise and Respiratory Physiotherapy Program on the Patient Undergoing Bariatric Surgery
The goal of this clinical trial is to see the impact of a physical exercise programme and respiratory physiotherapy before and after bariatric surgery in obese patients.
- Conditions
- Bariatric Surgery and Physical Activity, Obesity/Therapy, Bariatric Surgery Complications, Bariatric Patients
- Trial name
- CAPS-OB (NCT06987903)
- Testing
- Pre- and post-operative physical exercise programme, Pre- and post-operative respiratory physiotherapy
- Where
- Spain
- Volunteers
- 132 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Obesity and Overweight
Effects of Ultra Processed Food on Intestinal Energy Harvest
Ultra processed food is everywhere in modern society and may contain multiple ingredients that affect the way participants' bodies store energy.
- Trial name
- UPFEH (NCT06853288)
- Testing
- Diet containing 80% ultra processed foods, Diet containing 20% ultra processed foods
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Columbia University
Obesity, Physical Inactivity
Exercise Snacks Enabled by an mHealth Intervention Delivered in General Practice to Promote a Sustainable Active Lifestyle in Adults With Obesity
Adults with obesity gain as much from regular physical activity as anyone else, but structured exercise programmes are hard to sustain once the programme ends.
- Conditions
- Obesity, Physical Inactivity, Sedentary Behavior
- Trial name
- SnackFIT (NCT07867665)
- Testing
- Exercise snacks programme, Conversational agent, Wrist-worn activity tracker
- Where
- 3 sites in Czechia
- Volunteers
- 306 people
- Sponsor
- Charles University, Czech Republic
Sacropenic Obesity
Effects of the EatWelLog App on Enhancing Diet Management for Older Adults With Sarcopenic Obesity
Background: Sarcopenic obesity (SO) affects 10% of older adults increased to 23% of those 75+, raising health risks and health cost.
- Trial name
- NCT07867795
- Testing
- Dietary Modification programme, Exercise Training, The EatWelLog App
- Where
- Hong Kong
- Volunteers
- 212 people
- Sponsor
- The Hong Kong Polytechnic University
Child Obesity
Community Active and Healthy Families Pragmatic Trial
This is a randomized pragmatic trial of the Community-AHF intervention to evaluate its effectiveness at decreasing body mass index in 5-12 year old children.
- Trial name
- NCT07868471
- Testing
- Community Active and Healthy Families Intensive Health Behavior and Lifestyle Treatment
- Volunteers
- 416 people
- Sponsor
- University of Colorado, Denver
Dietary Assessment, Dietary and Lifestyle Behaviour Change
BRE-13: Mediterranean Diet
Explore the effect of MedDiet vs. Usual Diet on circulating and breast tumor fatty acid profiles. The investigators aim to examine impact on tumor biology in newly diagnosed participants.
- Conditions
- Dietary Assessment, Dietary and Lifestyle Behaviour Change, Dietary Behavior, Metabolic Health
- Trial name
- BRE-13 (NCT07869355)
- Testing
- Explore the effect of MedDiet vs. Usual Diet on Fatty Acid Profile, Explore the effect of MedDiet vs. Usual Diet on Breast Tumor Tissue, Explore the effect of MedDiet vs. Usual Diet on Lipids
- Volunteers
- 30 people
- Sponsor
- University of Illinois at Chicago
Obese Individuals, Central Adiposity
Post-exercise Blood Pressure With Inorganic Nitrate
This study is examining whether acute inorganic nitrate supplementation in the form of beetroot juice, paired with an acute bout of exercise, affects blood pressure and what is the magnitude of the difference compared to exercise…
- Trial name
- BEET-DOWN (NCT07869472)
- Testing
- Beetroot Juice - Active + Exercise, Beetroot Juice - Active + No exercise
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Obesity, Child Obesity
Family COMIDA (Consumo de Opciones Más Ideales De Alimentos) (Eating More Ideal Food Options)
The purpose of this study is to determine the most effective family-centered intervention (FCI) for weight loss and obesity prevention in Hispanic families.
- Conditions
- Obesity, Child Obesity, Weight Loss
- Trial name
- NCT07144800
- Testing
- Parent Weekly Individual Telephone Support, Child Education, Parent Initial Counseling
- Where
- United States
- Volunteers
- 1,319 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center