Clinical trials: Obesity; Overweight
Morbid Obesity, Surgery
Oxygen Reserve Index: Utility as Early Warning for Desaturation in Morbidly Obese Patients
The Oxygen Reserve Index (ORi) is a reference that could help clinicians with their assessments of normoxic and hyperoxic states by scaling the measured absorption information between 0.00 and 1.00.
- Trial name
- NCT03021551
- Testing
- Rainbow sensor
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Masimo Corporation
Obesity
Naltrexone/Bupropion (Mysimba) to Optimize Weight Outcomes After Obesity Surgery
Limited/poor weight loss and weight regain are concerns following bariatric surgery, and weight regain may increase the risk for relapse of comorbidities related to obesity.
- Trial name
- NCT04399395
- Testing
- Naltrexone/bupropion, Lifestyle
- Sponsor
- Oslo University Hospital
Perioperative Care, Bariatric Surgery
Do Text Message Reminders Increase Preoperative Exercise in Obesity Surgery Candidates?
Preoperative exercise has been shown to improve physiological and functional capacity in patients undergoing abdominal surgery to prepare them for the stress of surgery.
- Conditions
- Perioperative Care, Bariatric Surgery, Obesity
- Trial name
- NCT01607177
- Testing
- Daily text message reminders
- Where
- New Zealand
- Volunteers
- 102 people
- Sponsor
- University of Auckland, New Zealand
Obesity & Overweight, Obesity (Disorder)
Optimizing Self-Monitoring Feedback Delivery for the Treatment of Overweight and Obesity
The purpose of this research study is to learn how to best provide weekly feedback on individual progress toward intervention goals during a weight loss program.
- Trial name
- NCT07227051
- Testing
- Feedback on Calorie Goal Attainment, Feedback on Dietary Quality, Feedback on Physical Activity Goal Attainment
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Parental Stress, Parent and Child Stress
Family Based Mindfulness Intervention
The goal of the proposed interdisciplinary study is to assess feasibility of recruiting a pilot sample of parents of toddlers and engaging them in a pilot study to test a version of mindfulness-based intervention for parenting…
- Conditions
- Parental Stress, Parent and Child Stress, Parental and Child Obesity, Child Obesity
- Trial name
- NCT01974102
- Testing
- Lifestyle counseling, Parenting Mindfully for Health (PMH)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Yale University
Obesity
Phase 2a Obesity Study of Oral Doses of Oleoyl-Estrone (MP-101)
The purpose of this study is to evaluate the safety, preliminary efficacy, and pharmacokinetics of two 14-day cycles of escalating oral doses of MP 101 in 100 obese adult subjects.
- Trial name
- NCT00449202
- Testing
- oleoyl-estrone (MP 101)
- Where
- 3 sites in United States, Switzerland
- Volunteers
- 100 people
- Sponsor
- Manhattan Pharmaceuticals
Overweight, Obesity
Protein, Fiber, and Metabolic Syndrome - The PROFIMET Study
Randomized controlled single-blinded intervention study in 111 overweight and obese subjects with risk factors of developing type 2 diabetes, with the aim to investigate effects of isoenergetic high cereal fiber as compared with…
- Conditions
- Overweight, Obesity, Metabolic Syndrome
- Trial name
- PROFIMET (NCT00579657)
- Testing
- control diet, supported by dietary supplement twice daily, high cereal fiber diet, supported by dietary supplement twice daily, high protein diet, supported by dietary supplement twice daily
- Where
- 4 sites in Germany, United Kingdom
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- German Institute of Human Nutrition
Obesity
Prevention & Promotion in the Treatment of Obesity
Making healthy food choices requires sacrificing immediate pleasures of consuming high calorie foods in order to achieve long-term health goals.
- Trial name
- PROSPER (NCT02990494)
- Testing
- STANDARD, PREVENT, PROMOTE
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Obesity, Neostigmine
Observational Study in Bariatric Surgery
Obesity in the world represents a growing share of the general population. At hospital, the management of these patients could be problematic especially when calculating the drug dosage.
- Conditions
- Obesity, Neostigmine, Residual Neuromuscular Blockade
- Trial name
- NEOCURE (NCT04244266)
- Testing
- NO INTERVENTION, it is an observational study
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Metabolomics, Obesity
Metabolomic Profiling in Adolescents With Obesity and Diabetes
The purpose of this study is to identify unique metabolite signatures associated with the development of Type 2 diabetes and diabetic kidney disease in children.
- Conditions
- Metabolomics, Obesity, Diabetes, Diabetic Nephropathies
- Trial name
- NCT02145572
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obesity, Severe Obesity
Energy Expenditure From ECAL Indirect Calorimeter in a Multicomponent Weight Management Service
Whether greater weight loss is as a result of a smaller reduction in energy expenditure with caloric restriction is not known. Resting energy expenditure and 24-hour energy expenditure vary substantially between individuals.
- Conditions
- Obesity, Severe Obesity, Sleep Apnoea
- Trial name
- ECAL (NCT03638895)
- Testing
- ECAL Indirect Calorimeter, Diet, exercise & behaviour modification therapy
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Sleep Apnea, Obstructive, Obesity Hypoventilation Syndrome
Feasibility of a Modified Positive Airway Pressure Device to Treat Sleep Disordered Breathing
This study will use a modified version of a positive airway pressure device to supply air to the participant, while undergoing supervised polysomnography.
- Trial name
- NCT02368639
- Testing
- Fisher & Paykel Healthcare PAP Device
- Where
- New Zealand
- Volunteers
- 14 people
- Sponsor
- Fisher and Paykel Healthcare
Pediatric Obesity, Metabolic Syndrome
Cardio-Metabolic Risk Evaluation in Overweight and Obese Children
Metabolic and cardio-vascular complications can often appear in overweight and obese children from an early age. Currently, there are few studies in the specialized literature that correlate clinical, biological and ultrasound…
- Conditions
- Pediatric Obesity, Metabolic Syndrome, Nonalcoholic Fatty Liver, Atherosclerosis
- Trial name
- CardMetSOb (NCT05908877)
- Testing
- History and Clinical evaluation, Biological evaluation of the metabolic syndrome and components, Ultrasound evaluation of subclinical atherosclerosis and visceral fat storage
- Where
- Romania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Neoped - Centru de Pediatrie
Obesity, Cardiovascular Diseases
A Clinical Trial Of Two Educational Strategies In Cardiovascular Health In Child Population
AIM: To evaluate the effectiveness of two strategies in cardiovascular risk in children 2º grade in the community of Madrid. DESIGN: cluster-randomized trial with blinded evaluator SCOPE AND SUBJECTS OF STUDY: Children of both…
- Trial name
- SAVINHEARTS (NCT01418872)
- Testing
- Didactic Concerts
- Where
- Spain
- Volunteers
- 1,730 people, healthy volunteers welcome
- Sponsor
- Agencia Lain Entralgo
Severe Obesity
Effects of Long Biliopancreatic Limb Versus Long Alimentary Limb in Superobesity, a Randomized Study
Surgical bypassing of a longer section of the small bowel (when doing a gastric bypass operation) gives better results on body weight in the superobese.
- Trial name
- BMI>50 (NCT02033577)
- Testing
- Distal gastrojejunal bypass, RYGB
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Aleris Obesity
Obesity
Endoscopic Suturing System for Tissue Apposition
The objective of this feasibility trial is to evaluate the Ethicon Endo-Surgery Endoscopic Suturing System (ESS) for tissue apposition and reduction of the size of a dilated GJ anastomosis in subjects who are regaining weight…
- Trial name
- NCT00495222
- Testing
- Tissue plication, Endoscopic Suturing System
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Ethicon Endo-Surgery
High Cholesterol, Diabetes
Complete Lifestyle Medicine Intervention Program
This project will use a mixed design and will be conducted at the West Parry Sound Health Centre. Based on similar studies there is an expected 10% drop-out rate so 20 participants per group will be invited to aim to have 15…
- Conditions
- High Cholesterol, Diabetes, Obesity, Hypertension
- Trial name
- CLIP (NCT06192251)
- Testing
- Lifestyle Medicine
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Northern Ontario School of Medicine
Health Status Unknown, Obesity
Patients Navigators in Facilitating Weight Management in Obese Participants
This trial studies the effectiveness of patient navigators in facilitating weight management in obese participants. Health coaches or patient navigators may help more participants take part in weight management programs.
- Trial name
- NCT03674229
- Testing
- Informational Intervention, Questionnaire Administration, Telephone-Based Intervention
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- M.D. Anderson Cancer Center
Obesity, Type 2 Diabetes
Feel4Diabetes-study
The aim of the Feel4Diabetes-study is to develop, implement and evaluate a community-based intervention aiming to create a more supportive social and physical environment to promote lifestyle and behaviour change to prevent type…
- Trial name
- Feel4Diabetes (NCT02393872)
- Testing
- Feel4Diabetes-intervention
- Where
- Greece
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Obesity and Hypogonadism
Lifestyle Intervention and Testosterone Replacement in Obese Seniors
The prevalence of obesity in Veterans is greater than in the general population, and even more so among users of the VA Health Care System.
- Trial name
- LITROS (NCT02367105)
- Testing
- Testosterone, Lifestyle Therapy
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- VA Office of Research and Development
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