Clinical trials: OSA - Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA), Snoring
OSAHS Screening in Diverse Populations
The goal of this prospective observational study is to learn about the current prevalence of obstructive sleep apnea-hypopnea syndrome in community population, patients with specific diseases and special population from China.
- Conditions
- Obstructive Sleep Apnea (OSA), Snoring, Prevalence, Questionnaires and Surveys
- Trial name
- NCT07736872
- Testing
- patients with hypertension, diabetes, cardiovascular and cerebrovascular diseases, chronic obstructive pulmonary disease, asthma and other OSA related comorbidities.
- Where
- 2 sites in China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Kang Wu
Hypertension, Obstructive Sleep Apnea (OSA)
How Wall Squat Exercise Affects Blood Pressure in People With High Blood Pressure and Treated Sleep Apnea (WALLPRESS)
This study will look at whether a simple exercise called the isometric wall squat can help lower blood pressure in adults who have both hypertension and obstructive sleep apnoea treated with CPAP.
- Trial name
- WALLPRESS (NCT07730879)
- Testing
- Isometric Wall Squat
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Aveiro University
OSA - Obstructive Sleep Apnea, Palatal Expansion Technique
Miniscrew-Assisted Rapid Palatal Expansion for Obstructive Sleep Apnea
The goal of this clinical trial is to learn whether miniscrew-assisted rapid palatal expansion (MARPE) can improve obstructive sleep apnea (OSA) in late adolescents and adults aged 16 to 60 years.
- Trial name
- NCT07734688
- Testing
- Miniscrew-Assisted Rapid Palatal Expansion, Standard Care (in control arm)
- Volunteers
- 24 people
- Sponsor
- University of Malaya
Obstructive Sleep Apnea, Obstructive Sleep Apnea (OSA)
Identification of Biomarkers of Obstructive Sleep Apnea.
Obstructive sleep apnea (OSA) is a common sleep disorder associated with intermittent hypoxia, systemic inflammation, oxidative stress, and an increased risk of cardiovascular and metabolic diseases.
- Conditions
- Obstructive Sleep Apnea, Obstructive Sleep Apnea (OSA), Obstructive Sleep Apnea (OSAS), Obstructive Sleep Apnea (SAOS)
- Trial name
- NCT07723144
- Testing
- Positive Airway Pressure (PAP) Therapy
- Where
- Poland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Obstructive Sleep Apnea (OSA), Sleep Apnea - Obstructive
Clinical Trial of the Cryosa System for the Treatment of Obstructive Sleep Apnea (OASIS)
The objective of this study is to evaluate the safety and effectiveness of the Cryosa System when used as intended to perform the Cryosa Procedure.
- Conditions
- Obstructive Sleep Apnea (OSA), Sleep Apnea - Obstructive, OSA
- Trial name
- (OASIS) (NCT07720219)
- Testing
- Cryosa Procedure
- Volunteers
- 130 people
- Sponsor
- Cryosa, Inc.
Obstructive Sleep Apnea (OSA), Insomnia
Validating the Use of a Subjectively Reported Sleep Vital Sign
Sleep disorders are commonly under-recognized in the primary care setting and available screening tools are often are limited. The study inestigators hypothesize that the use of a novel subjective sleep vital sign (VS) will…
- Conditions
- Obstructive Sleep Apnea (OSA), Insomnia, Restless Leg Syndrome (RLS), Hypersomnia Type; Sleep Disorder
- Trial name
- SVS (NCT03018912)
- Testing
- Sleep VS
- Where
- United States
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obstructive Sleep Apnea (OSA)
Assessing the Validity of the PAP Problems Triage Tool in Patients With PAP Treatment for Obstructive Sleep Apnea
The intended use of the Positive Airway Pressure (PAP) Problems Triaging Tool (TT) is to appropriately triage patients with a PAP-associated problem(s) to a specific intervention(s) based on patient responses.
- Trial name
- TriagingTool (NCT05530967)
- Testing
- TT, VE
- Where
- United States
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obstructive Sleep Apnea (OSA), Positional Obstructive Sleep Apnea
Effectiveness of Audio Cues to Achieve Positional Therapy in Patients With Positional Obstructive Sleep Apnea
Patients with obstructive sleep apnea (OSA) often experience more frequent and severe breathing disturbances when sleeping in the supine (back-sleeping) position compared with non-supine positions.
- Trial name
- NCT07714330
- Testing
- Investigational Positional Therapy Device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- SleepDev, Inc
OSA, Heart Failure
Impact of Early Diagnosis and Treatment of OSA on Hospital Readmission in Hospitalized Cardiac Patients
The purpose of this study is to determine whether early diagnosis of obstructive sleep apnea and initiation of and adherence to CPAP therapy in hospitalized cardiac patients would impact 30-day hospital readmission rates.
- Conditions
- OSA, Heart Failure, Myocardial Infarction, Arrhythmia, Cardiac
- Trial name
- CV Readmit (NCT03647891)
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obstructive Sleep Apnea (OSA)
CPAP Population Management
The investigators propose a study to formally compare two Continuous Positive Airway Pressure (CPAP) follow-up pathways: 1) Usual care - follow-up visits reflect standard care practice and we rely on patients to reach out to us…
- Trial name
- NCT04559737
- Testing
- Case Management
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obstructive Sleep Apnea, OSA
Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Neurostimulation
Multi-center, open-label, prospective, randomized clinical trial of the aura6000(R) System for the reduction of apnea and hypopneas in adult patients with moderate to severe obstructive sleep apnea who have failed or are…
- Conditions
- Obstructive Sleep Apnea, OSA, Apnea, Apnea, Obstructive
- Trial name
- OSPREY (NCT04950894)
- Testing
- Hypoglossal Nerve Stimulation
- Where
- 19 sites in United States
- Volunteers
- 107 people
- Sponsor
- LivaNova
Obstructive Sleep Apnea (OSA), Syndrome, Obstructive Sleep Apnea
Implantable Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea
The objective of this study is to evaluate the safety and preliminary effectiveness of an implantable hypoglossal nerve stimulation system for moderate-to-severe obstructive sleep apnea (OSA).
- Conditions
- Obstructive Sleep Apnea (OSA), Syndrome, Obstructive Sleep Apnea, Respiration Disorders, Sleep Apnea Syndrome, Obstructive
- Trial name
- NCT07711678
- Testing
- Implantable Hypoglossal Nerve Stimulation System
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Beijing Pins Medical Co., Ltd
Obstructive Sleep Apnea (OSA)
DAW2020 on OSA Endotypic Traits
Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. Some OSA patients with low arousal threshold wake up prematurely during an obstructive event and do not have time for…
- Trial name
- SedOSA (NCT04538755)
- Testing
- DAW2020 oral capsule
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Sleep Apnea Obstructive (OSA)
Micromanaging Human Sleep Physiology to Treat Sleep Apnea and Other Disorders
This study will examine whether a combination of breathing training during wake and targeted reactivation of the training during sleep can induce breathing changes during sleep and subsequent cognitive benefits during wake.
- Trial name
- NCT06926036
- Testing
- Wake training + TMR
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Northwestern University
Obstructive Sleep Apnea (OSA)
Clinical Trial of the Cryosa System for the Treatment of Obstructive Sleep Apnea (ARCTIC_AUS)
This is a prospective, multicenter, non-randomized single-arm safety and performance study to collect data to evaluate the safety of the Cryosa procedure to treat obstructive sleep apnea (OSA) in patients with moderate to severe…
- Trial name
- NCT07021833
- Testing
- Cryosa Procedure
- Sponsor
- Cryosa, Inc.
Obstructive Sleep Apnea (OSA), Suspected Obstructive Sleep Apnea
Empirical CPAP Therapy for Suspected Obstructive Sleep Apnea in a Resource-Limited Setting
Obstructive sleep apnea (OSA) is a condition where a person's airway repeatedly collapses during sleep, causing them to stop breathing briefly and disrupting their rest.
- Conditions
- Obstructive Sleep Apnea (OSA), Suspected Obstructive Sleep Apnea, Sleep Apnea Syndromes
- Trial name
- NCT07693101
- Volunteers
- 80 people
- Sponsor
- Assiut University
Obstructive Sleep Apnea (OSA)
Level 3 Validation Study
This study will compare the output of a new Level 3 polysomnography system against in-laboratory polysomnography.
- Trial name
- NCT07688603
- Testing
- Comparison 1: Level 1 Polysomnography: Cadwell/Alice, Comparison 2: Level 3 Test: Berry Sleep Apnea Screening Monitor
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Windsor Sleep Disorders Clinic
OSA - Obstructive Sleep Apnea
The Optimal One-Month Dosing of Lemborexant for Moderate Obstructive Sleep Apnea (OSA) Patients With Low Arousal Threshold
The goal of this clinical trial is to investigate the 1-month treatment effects of different dose of lemborexant in moderate OSA adult patients (18-65 years of age) with low arousal threshold.
- Trial name
- LMOSALAT (NCT07683442)
- Testing
- Lemborexant 5 MG [Dayvigo] Period 1, Lemborexant 5 MG [Dayvigo] Period 2, Lemborexant 5 MG [Dayvigo] Period 3
- Where
- Thailand
- Volunteers
- 36 people
- Sponsor
- Chulalongkorn University
Obstructive Sleep Apnea (OSA)
Mandibular Advancement Device (MAD) and Continuous Positive Airway Pressure (CPAP) for Treatment of Adult Patients Diagnosed With Moderate Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a frequent illness related to sleep and breathing with many symptoms and complications. The primary choices of treatment are continuous positive airway pressure (CPAP) and removable appliance for…
- Trial name
- NCT07677332
- Testing
- Mandibular advancement device (MAD), Continuous positive airway pressure (CPAP)
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- University of Copenhagen
Asthma, Obstructive Sleep Apnoea (OSA)
Is Asthma in Subjects With Obstructive Sleep Apnoea (OSA) Due to Dysanapsis
Intention to review patient letters from sleep clinic to see if their lung function fit in with Dysynapsis in wheezing patients or if it is true asthma
- Conditions
- Asthma, Obstructive Sleep Apnoea (OSA), Dysanapis
- Trial name
- NCT04142905
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust