Clinical trials: Nutritional Interventions
Hypercholesterolemia
Observation of the Effects of Guideline-driven Lifestyle Interventions, Including Use of a Red-yeast Based Nutraceutical
The objective of the present multinational, multicentre, prospective, scientific study is to confirm that prescription of a low-dose red yeast-based nutraceutical.
- Trial name
- NCT05000541
- Where
- 7 sites in Austria, Germany
- Volunteers
- 259 people
- Sponsor
- Mylan Inc.
Infant Development, Glucose, High Blood
Effect of Nutritional Intervention on Metabolic Response in Infants
The purpose of this study is to determine the glucose response of complementary feeding regimens consisting of two different follow-up formulas (FUFs) and infant cereals (ICs).
- Trial name
- NCT04483453
- Testing
- EXPL feeding regimen, CTRL feeding regimen
- Where
- Philippines
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Type II Diabetes Mellitus
A Study Evaluating the Efficacy and the Benefit of Integrated Personalized Diabetes Management (PDM) for Diabetic Patients.
This study is a German, prospective, multicenter, controlled, cluster-randomized, interventional comparative study evaluating the efficacy and benefits of integrated PDM care by measuring HbA1c levels in patients with Type 2…
- Trial name
- PDMProValueDSP (NCT02156349)
- Testing
- Accu-Chek Smart Pix Software, Accu-Chek Smart Pix readout Device
- Where
- 50 sites in Germany
- Volunteers
- 558 people
- Sponsor
- Hoffmann-La Roche
Knee Discomfort
Effect of Consuming a Bioactive Compound (EPP) on Joint Health in Healthy Adults
The objective of this trial is to determine the efficacy of oral administration of a bioactive compound (EPP) in healthy individuals with mild knee joint discomfort.
- Trial name
- NCT06650670
- Testing
- Dietary Supplement: EPP
- Where
- Spain
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Biosearch S.A.
Critical Illness, Dietary Modification
Meeting Protein Targets in Critically Ill Patients
This is a retrospective study of protein and energy intake in enterally fed critically ill adult patients before and after the introduction of a very high protein enteral nutrition formula in a single center medical/surgical ICU.
- Trial name
- PROTARGET (NCT03319836)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Société des Produits Nestlé (SPN)
Leber's Hereditary Optic Neuropathy (LHON)
Study to Assess the Efficacy and Safety of Raxone in LHON Patients
LEROS is an open-label interventional Phase IV study, designed to further assess the efficacy and safety of Raxone® in the long-term treatment of LHON patients.
- Trial name
- LEROS (NCT02774005)
- Testing
- Idebenone
- Where
- 29 sites in United States, Austria and 8 more
- Volunteers
- 199 people
- Sponsor
- Santhera Pharmaceuticals
Childhood Obesity
Evaluation of a Commercial Gaming Impact in a Childhood Obesity Intervention
Recently, researchers have been interested in the use of game play, mechanics and psychology for health-related engagement and behavior change.
- Trial name
- NCT01757925
- Testing
- weight managment program, Active Gaming
- Where
- 11 sites in United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- UnitedHealth Group
Overweight and Obesity
Mobile Phone Intervention for Physical Activity Maintenance in African American Men (MobileMen)
African American men are at risk of developing chronic disease partly due to low levels of regular physical activity. Studies have been effective in increasing physical activity levels in African American men; however for the…
- Trial name
- NCT03055416
- Testing
- Mobile Men App Prototype
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Dietary Modification
Evaluation of Bioavailability of Phenolic Compounds From Oxxynea®
The aim of this study is to evaluate bioavailability and pharmacokinetics of phenolic compounds from Oxxynea®, a blend of fruit and vegetable extracts, in healthy volunteers, during a randomized, double-blind and cross-over…
- Trial name
- NCT03432104
- Testing
- Oxxynea®
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fytexia
Overweight and Obesity
Web-based Weight Loss Intervention
Excess weight is a major risk factor underlying leading causes of death globally, including cardiovascular disease, type 2 diabetes, and some cancers.
- Trial name
- NCT03400696
- Testing
- Lower carbohydrate diet, Higher fiber diet, Physical activity focused
- Where
- 2 sites in United States
- Volunteers
- 63,656 people, healthy volunteers welcome
- Sponsor
- 23andMe, Inc.
Faltering Growth
Intervention Study to Investigate the Effects of ONS Use Among Malaysian Children With Faltering Growth
A randomised, open label, controlled intervention study to test the effect of the test product with dietary counselling versus dietary counselling alone on Weight-for-Age z-score change in children from ≥ 1 to ≤ 6 years of age…
- Trial name
- MONS (NCT05193630)
- Testing
- Milnutri Sure™
- Where
- Malaysia
- Volunteers
- 172 people
- Sponsor
- Danone Specialized Nutrition (M) Sdn Bhd
Type 2 Diabetes, Diabetes Mellitus Type 2
AIM-MET: AI-Guided Microbiome-Targeted Nutrition for Glycemic Improvement in Type 2 Diabetes
AIM-MET is a randomized clinical study testing whether a fixed microbiome-targeted nutritional product can improve blood sugar control in adults with type 2 diabetes when used in addition to usual stable diabetes treatment.
- Trial name
- AIM-MET (NCT07622628)
- Testing
- Microbiome-targeted oral food supplement
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- ENBIOSIS BIOTECHNOLOGIES
Hypercholesterolemia, Dyslipidemias
A Study to Evaluate the Effectiveness and Safety of Fixed-Dose Combination of Pitavastatin/ Ezetimibe
The objective of this study is to evaluate the effectiveness and safety of Pitavastatin/Ezetimibe FDC in patients with hypercholesterolemia.
- Trial name
- PIVOTAL (NCT07083206)
- Where
- South Korea
- Volunteers
- 4,500 people
- Sponsor
- Ahn-Gook Pharmaceuticals Co.,Ltd
Obesity, Overweight
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)
The purpose of this pediatric, chronic weight management, Phase 3 Master Protocol (PWMP) is to create a framework to evaluate the safety and efficacy of pharmacologic agents for the treatment of obesity or overweight in pediatric…
- Trial name
- ADVANCE (NCT06672549)
- Testing
- Orforglipron
- Where
- 116 sites in United States, Belgium and 11 more
- Volunteers
- 125 people
- Sponsor
- Eli Lilly and Company
Obesity
Evaluation of a Powered Stapler System on Surgical Interventions Required During Laparoscopic Sleeve Gastrectomy
This study will provide clinical data in an observational setting. Individuals undergoing LSG, and who meet study entry criteria, may be enrolled.
- Trial name
- NCT02358785
- Testing
- ECHELON FLEX™ Powered Plus Stapler
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Ethicon Endo-Surgery
Physiological Stress, Cognitive Performance
Dietary Intervention With Brain-friendly Diet
To evaluate the effect of dietary intervention on metabolic risk profile, and on potential simultaneous changes in physiological and cognitive functions and to collect a unique database using state-of-the-art technologies on…
- Conditions
- Physiological Stress, Cognitive Performance, LDL Cholesterol
- Trial name
- BRAVE (NCT03346486)
- Testing
- Control diet, Intervention diet
- Where
- Finland
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Fazer Group
Diabetes Mellitus, Type 2
An Intervention Program to Control Diabetes
Study to evaluate the effectiveness of a structured intervention to improve diabetes control.
- Trial name
- NCT00543621
- Testing
- daily enteral nutritional product and/or behavioral changes
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Abbott Nutrition
Diabetes Mellitus Self Management Education, Diabetes
Digital Health Intervention On Awareness Of Vaccination Against Influenza Among Adults With Diabetes
The study leveraged the Dario digital health platform to retrospectively analyze data from 64,904 users with diabetes assigned by the platform into three groups: Group A received previously studied monthly flu nudge messages…
- Trial name
- NCT06840236
- Testing
- Adapted Flu nudge messages, Previously studied based on RCT
- Where
- Israel
- Volunteers
- 8,431 people
- Sponsor
- LabStyle Innovations Ltd.
Metabolic Syndrome, Gut Bacteria
Health Improvement Through Food and Lifestyle Intervention Based On Personalized Retail Advice
FLORA is a longitudinal intervention study with a randomized, parallel group design. Primary objective is to improve metabolic health through gut microbiota modulation by means of a retailer-driven personalized dietary…
- Conditions
- Metabolic Syndrome, Gut Bacteria, Personalized Nutrition
- Trial name
- FLORA (NCT04102891)
- Testing
- Microbiota modulation diet
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- SmartWithFood
Osteoporosis
HDDO-1614 Intervention Trial
Randomized, Open-label, Single-dose, 3-period, 6-sequence, 3-way crossover Study
- Trial name
- NCT03234244
- Testing
- Bazedoxifene 20 mg, Cholecalciferol, Bazedoxifene 20mg and Cholecalciferol
- Where
- South Korea
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Hyundai Pharmaceutical Co., LTD.