Clinical trials: Nutritional Deficiency
Vitamin D Deficiency
Controlled Trial of Prenatal Vitamin D3 Supplementation to Prevent Vitamin D Deficiency in Mothers and Their Infants
The purpose of this research study is to compare the effects of higher dose vitamin D with commonly recommended dose in pregnant women to see which is better in achieving and/or maintaining sufficient vitamin D blood levels…
- Trial name
- PA 03-103 (NCT00610688)
- Testing
- Prenatal Vitamin, Cholecalciferol (Vitamin D3)
- Where
- 2 sites in United States, United Arab Emirates
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Fanconi Anemia
Hematopoietic Stem Cell Transplantation for Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using Total Body Irradiation, Cyclophosphamide and Fludarabine
The purpose of this research study is to: (1) determine if the combination of low dose total body irradiation, low dose cyclophosphamide and the addition of fludarabine, and a serum to suppress the immune system can allow…
- Trial name
- NCT00595127
- Testing
- Cyclophosphamide, Fludarabine, Total body irradiation (TBI)
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Secondary Hyperparathyroidism
Suspected Deficient Activation of Vitamin D in Patients With Secondary Hyperparathyroidism
The purpose of this study is to determine if a reduction in the enzyme 1-hydroxylase, which activates Vitamin D, is the cause of overactivity of the parathyroid glands (called secondary hyperparathyroidism - normal blood calcium…
- Trial name
- 1hydroxylase (NCT00754442)
- Testing
- Teriparatide
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Vitamin D Deficiency, Pre-Eclampsia
Effect of Vitamin D3 Supplementation in Pregnancy on Risk of Pre-eclampsia
Vitamin D deficient pregnant ladies were selected and randomized into 2 groups for routine daily dose of multivitamin (400IU vitamin D3) versus maximum safest treatment daily dose (4000IU vitamin D3).
- Trial name
- NCT03101150
- Testing
- 400 IU Vitamin D3, 4000 IU Vitamin D3
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- King Fahad Medical City
PCOS, Depression
Metformin, Vitamin D, and Depression in Polycystic Ovary Syndrome (PCOS) Trial
Open-label randomized clinical trial assessing the efficacy of Metformin versus Vitamin D in improving symptoms of depressed mood in polycystic ovary syndrome.
- Conditions
- PCOS, Depression, Vitamin D Deficiency, Insulin Resistance
- Trial name
- MINDD (NCT03380091)
- Testing
- Metformin, Vitamin D
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Vitamin D Deficiency
Safety of Vitamin D Supplementation in Older Persons
This study will evaluate the safety over 6 months of two different doses of vitamin D (cholecalciferol) in men and women age 65 and older. It will also evaluate if supplementation with vitamin D improves physical performance.
- Trial name
- NCT00681590
- Testing
- cholecalciferol (vitamin D)
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Miami
Hookworm Infection, Hookworm Disease
Safety and Immunogenicity Study of Na-GST-1 With or Without CpG
Na-GST-1 is a protein expressed during the adult stage of the hookworm life cycle that is thought to play a role in the parasite's degradation of host hemoglobin for use as an energy source.
- Trial name
- NCT02143518
- Testing
- Na-GST-1/Alhydrogel®, CpG 10104
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
G6PD Deficiency
Evaluation of a Diagnostic to Identify Glucose-6-phosphate Dehydrogenase (G6PD) Deficiency in Brazil
Th objectives of this study are: To determine the performance of G6PD tests in detecting G6PD activity and hemoglobin (Hb) compared to a reference assay To assess the comprehension of the G6PD test packaging and labelling among…
- Trial name
- NCT04033640
- Testing
- SD Biosensor STANDARD G6PD Test, Pointe Scientific Test Kit, HemoCue System
- Where
- 2 sites in Brazil
- Volunteers
- 1,754 people, healthy volunteers welcome
- Sponsor
- PATH
Malnutrition
Prospective Evaluation of NOTES (Natural Orifice Translumenal Endoscopic Surgery) PEG "Rescue"
The purpose of this study is to determine: 1. Utility of urgent upper endoscopy in setting of dislodges (percutaneous endoscopic gastrostomy) PEG tube. 2.
- Trial name
- PEGRescue (NCT01119040)
- Testing
- Natural Orifice Translumenal Endoscopic Surgery
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Urea Cycle Disorder
Manipulating the Gut Microbiome Study
The objective is to determine if acetohydroxamic acid (AHA) can prevent hydrolysis of urea by inhibiting the bacterial urease of gut flora of both healthy control adults as well as adults with urea cycle disorders
- Trial name
- NCT03181828
- Testing
- Acetohydroxamic Acid Oral Tablet, No treatment
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Nicholas Ah Mew
Vitamin d Deficiency
Blue Sky Study: Impact of Milk and Vitamin D for Child Growth and Health
This intervention study will address the impact of vitamin D fortified milk and vitamin D supplements on the growth, levels of vitamin D, insulin-like growth factor 1, growth hormone, academic attention, respiratory infections…
- Trial name
- BSS (NCT00886379)
- Testing
- Mongolian milk without vitamin D, Mongolian milk with vitamin D, UHT milk
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Vitamin D Deficiency
Personalized Vitamin D Supplementation in European and African Americans
The proposed study is a randomized, double-blind, controlled, multi-center clinical trial of six months of daily oral vitamin D3 (cholecalciferol).
- Trial name
- NCT02362269
- Testing
- Vitamin D
- Where
- 2 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Vitamin D Deficiency
Evaluation of Vitamin D Requirements During Pregnancy
The purpose of this study is to determine the effectiveness of vitamin D supplementation during pregnancy starting at the beginning of the second trimester.
- Trial name
- NCT00292591
- Testing
- cholecalciferol (vitamin D3), cholecalciferol
- Where
- United States
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Arterial Stiffening, Aging
Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women
The purpose of this study is to find out why women's arteries stiffen as they go through menopause, and how this is affected by estrogen loss.
- Conditions
- Arterial Stiffening, Aging, Menopause
- Trial name
- SHAPE (NCT00608062)
- Testing
- GnRHant - Ganirelix acetate, Transdermal estradiol patch
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obesity, Visceral, Cardiovascular Diseases
Impact of Liraglutide 3.0 on Body Fat Distribution
This study is a clinical study to investigate the efficacy of liraglutide compared to placebo in reducing visceral adiposity measured by MRI in overweight or obese subjects at high risk for cardiovascular disease after 40 weeks…
- Conditions
- Obesity, Visceral, Cardiovascular Diseases, Fat Disorder
- Trial name
- NCT03038620
- Testing
- Liraglutide
- Where
- United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Hypovitaminosis D
Comparing a Novel Phototherapy Kiosk to Oral Vitamin D Supplementation
The purpose of this project is to demonstrate the capability of a standing phototherapy kiosk (SPK) to stimulate cutaneous vitamin D3 and subsequent production of 25 Hydroxyvitamin (OH) D safely and as efficiently as an oral…
- Trial name
- NCT04556136
- Testing
- Standing Phototherapy Kiosk, D3 Oral supplement
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
G6PD Deficiency
Validation of a Diagnostic Test for Glucose-6-phosphate Dehydrogenase (G6PD) Deficiency in Anti-coagulated Blood
The primary objective of the study is to assess the accuracy of the SD Biosensor STANDARD™ point-of-care (POC) G6PD test in measuring G6PD activity and classifying results compared to a reference assay and across repeated…
- Trial name
- NCT04054661
- Testing
- SD Biosensor STANDARD G6PD Test, Pointe Scientific Test Kit, HemoCue System
- Where
- United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- PATH
Lynch Syndrome
Overcoming Barriers to the Uptake of Cascade Screening for Lynch Syndrome: Workbook Feasibility Study
The investigators will evaluate the feasibility of an intervention to improve Lynch syndrome cascade screening uptake. The investigators will conduct a pilot study among 15 patients diagnosed with Lynch Syndrome and 5 genetic…
- Trial name
- NCT04978350
- Testing
- Educational Workbook
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Chromium Deficiency, Diabetes Mellitus
Examination of the Effects of Chromium Levels on Glucose Metabolism, Lipid Metabolism, Morbidity and Mortality Rates in Patients Followed in Intensive Care Unit
The goal of this observational study is to determine the effects of chromium serum levels on glucose metabolism, lipid metabolism, morbidity and mortality rates in critically ill intensive care patients.
- Conditions
- Chromium Deficiency, Diabetes Mellitus, Hyperlipidemias, Hypercholesterolemia
- Trial name
- NCT06334042
- Testing
- Serum Chromium Level
- Where
- Turkey (Türkiye)
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Oguzhan Kahveci
Healthy
Bioequivalence Study of Colchicine Tablets
This randomized, single dose, three-way crossover study will evaluate the bioequivalence of two formulations of colchicine, the test product (colchicine 0.6mg Mutual) and a marketed combination product (colchicine 0.5 mg with…
- Trial name
- NCT01021020
- Testing
- Colchicine, Colchicine/Probenecid
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mutual Pharmaceutical Company, Inc.