Clinical trials: Nosocomial Infections
Crossing Infections, Drug Resistance, Microbial
Evaluation of Cost of Nosocomial Infection
This study will investigate the cost and impact of Healthcare Associated Infection (HAI) to patients, the health service and the wider community.
- Trial name
- ECONI (NCT03253640)
- Testing
- Exposure
- Where
- 2 sites in United Kingdom
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Glasgow Caledonian University
Infection
Use of Provodine to Protect HCW Hands (Aim II.1)
The investigators will assess whether applying Provodine, an FDA-approved hand hygiene product with a long duration of anti-microbial action, to healthcare workers' hands protects against self-contamination during the removal of…
- Trial name
- NCT03972826
- Testing
- Provodine
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Dysbiosis, Catheter-Related Infections
Cutaneous Microbiota Evolution in ICU Patients With CVC (ICMc)
Intensive Care Unit (ICU) patients are exposed to catheter-related infections with an important morbidity. Catheter colonization is constant but infection is not. Cutaneous dysbiosis could be the missing link.
- Trial name
- ICMc (NCT06095076)
- Testing
- Skin swabbing, Data collection
- Where
- French Guiana
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Death, Nosocomial Infection
Prophylactic Probiotics in Premature Infants
This study tries to determine whether the oral administration of a specific probiotic (good bacteria) in premature infants hospitalized in a neonatal intensive care unit may prevent infections and the development of a severe…
- Trial name
- C3P (NCT00727363)
- Testing
- Lactobacillus reuteri
- Where
- 8 sites in Colombia
- Volunteers
- 751 people, healthy volunteers welcome
- Sponsor
- Colombian Neonatal Research Network
Children, Only, Educational Problems
Toy Hygiene Education For Hospitalized Mothers
The present study aims to evaluate the effectiveness of toy hygiene education given to mothers of hospitalized children on their knowledge and practices, as well as the cleanliness of toy surfaces.
- Conditions
- Children, Only, Educational Problems, Hospital Infection
- Trial name
- NCT06199804
- Testing
- Toy Hygiene Training
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Sibel Küçükoğlu
COVID-19
COVID-19 Infection in Healthcare Workers
Introduction: The SARS-Cov-2 outbreak in France and the concomitant massive increase in the number of cases requiring hospital management create a major risk of COVID-19 infection for hospital staff.
- Trial name
- HOP-COVID (NCT04386759)
- Testing
- Cohort
- Where
- France
- Volunteers
- 1,858 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthcare Associated Infection
Evaluation of Healthcare Waste Management Practices and Problems Among Primary and Secondary Hospitals
Healthcare waste is defined as the total waste stream from a healthcare facility. Most of it (75-90%) is similar waste to domestic waste and is known as healthcare general waste and is made up of paper, plastic packaging, food…
- Trial name
- NCT06739863
- Testing
- healthcare waste management
- Where
- Pakistan
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Superior University
Multidrug Resistance
Point Prevalence Study of Multidrug-Resistant Organism Carriage by Healthcare Personnel
Acquisition and transmission of MDROs in healthcare facilities is a major patient safety problem, afflicting in particular the antibiotic-exposed and immunodeficient patient populations.
- Trial name
- NCT01952158
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Pseudomonas Aeruginosa, Colonization, Asymptomatic
Carbapenem-resistant Pseudomonas Aeruginosa: the SAMPAN Study.
Pseudomonas aeruginosa causes severe infections in hospitalized patients. The worldwide emergence of carbapenem-resistant P. aeruginosa (CRPA) makes infections by these pathogens almost untreatable.
- Conditions
- Pseudomonas Aeruginosa, Colonization, Asymptomatic, Nosocomial Infection
- Trial name
- SAMPAN (NCT05282082)
- Where
- 3 sites in Indonesia, Italy and 1 more
- Volunteers
- 2,105 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Nosocomial Infections, Pneumonia, Ventilator-Associated
A Efficacy and Safety Study of Nasal Prongs With Proprietary Surface Coating Aiming to Reduce Bacterial Colonization
The study is a first step in establishing the safety and efficacy of the CytaCoat technology when applied to a medical device such as a nasal prong and the clinical data generated will serve as a basis for continuous studies in…
- Trial name
- NCT02756351
- Testing
- CytaCoat Nasal Prong, Inspiration Healthcare Inspire nCPAP Nasal Prong
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- CytaCoat AB
Influenza, Influenza Prophylaxis
Oseltamivir and Baloxavir Marboxil for Prophylaxis Against Influenza Under a Hospital-based Setting
This study aims to randomly assign close contacts of hospitalized influenza virus patients to receive baloxavir marboxil prophylaxis, oseltamivir prophylaxis or no antiviral prophylaxis and monitor the incidence of clinical…
- Conditions
- Influenza, Influenza Prophylaxis, Nosocomial Infection
- Trial name
- NCT06762587
- Testing
- Baloxavir Marboxil, Oseltamivir
- Where
- China
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Hospital Infections, Environment, Controlled
CLEAN Frontline: A Stepped Wedge Cluster Trial
Environmental hygiene is a key component of infection prevention in healthcare, and a driver of healthcare associated infections.
- Conditions
- Hospital Infections, Environment, Controlled, Infection Control
- Trial name
- NCT05540886
- Testing
- TEACH CLEAN
- Where
- Cambodia
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
COVID-19, Molecular Sequence Variation
COVID-19 Genomic Sequencing for Nosocomial Outbreak Investigations
This is a tertiary care hospital-based prospective molecular epidemiology study in Montreal, Canada. When nosocomial transmission was suspected by local infection control teams' investigations, SARS-CoV-2 viral genomic sequencing…
- Conditions
- COVID-19, Molecular Sequence Variation, Nosocomial Infection
- Trial name
- NOSO-COVID (NCT05411562)
- Testing
- SARS-CoV-2 genomic sequencing
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Healthcare Associated Infection, Hand Hygiene
Effect of Video Camera Monitoring Feedback on Hand Hygiene Compliance and Infections in NICU
The purpose of this study is to determine if use of the video camera surveillance system for HH observation and performance feedback about HH compliance rates can improve the HH compliance of HCWs and reduce healthcare-associated…
- Conditions
- Healthcare Associated Infection, Hand Hygiene, Neonatal Infection
- Trial name
- CaM-HAI (NCT04053257)
- Testing
- Hand hygiene compliance observation with video camera surveillance system and performance feedback of the HH rates to HCWs
- Where
- Turkey (Türkiye)
- Volunteers
- 8,335 people, healthy volunteers welcome
- Sponsor
- Marmara University
Healthcare Associated Infection, Nosocomial Infection
Red Light Photobiomodulation and Topical Disinfectants
The goal of this clinical trial is to evaluate the potential effects of photobiomodulation when used with topical disinfectants in the anterior nares of healthy adults.
- Conditions
- Healthcare Associated Infection, Nosocomial Infection, Surgical Site Infection
- Trial name
- NCT05797818
- Testing
- Methylene Blue Only, Chlorhexidine Gluconate Only, Methylene Blue + Chlorhexidine Gluconate
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ondine Biomedical Inc.
Heart Failure, Healthcare Associated Infection
Ventricular Assist Device (VAD) Infection Prevention Survey
Annually, more than 250,000 patients in the U.S. with end-stage heart failure stand to benefit from ventricular assist device (VAD) therapy.
- Conditions
- Heart Failure, Healthcare Associated Infection, Ventricular Assist Device
- Trial name
- NCT03843021
- Testing
- VAD Infection Prevention Survey
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Influenza
Asymptomatic Flu Project
Although clinical presentation of influenza is often symptomatic, asymptomatic cases also occur. The knowledge of the incidence of asymptomatic influenza among healthcare workers is very important because of the risk of…
- Trial name
- AFP (NCT02868658)
- Testing
- Blood sampling, Nasal swab
- Where
- France
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Pathogen Resistance, Pneumococcal Infection
Aerosolized and Intravenous Colistin in Healthy Adults
Colistin is amphipathic, cannot be absorbed from the gastrointestinal tract and is administered intramuscularly, intravenously (IV) or via inhalation.
- Conditions
- Pathogen Resistance, Pneumococcal Infection, Pneumonia
- Trial name
- NCT01863719
- Testing
- Colistimethate sodium
- Where
- 2 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hand Hygiene, Surgical Wound Infection
Surgical Handwashing: Drying With One or Two Surgical Towels
This study aims to determine whether the use of two sterile towels for drying after surgical handwashing results in fewer contamination events compared to the use of only one towel among healthcare personnel.
- Conditions
- Hand Hygiene, Surgical Wound Infection, Healthcare Associated Infection, Medical Errors
- Trial name
- NCT06420934
- Testing
- Drying procedure after surgical handwashing
- Where
- Colombia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Instituto de Ortopedia Infantil Roosevelt
Craniotomy Surgery, Preventive Health Care
The Effect of Bundle Application on Surgical Site Infection
Surgical site infections (SSI) are the most common complications after surgical operations and are in the top three in Healthcare Associated Infections (HIE).
- Trial name
- NCT06724354
- Testing
- The Surgical Site Infections Precaution Package Form includes the parameters that should be applied to patients before, during and after surgery.
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Cukurova University