Clinical trials: Normal Gait
Liver Disease, Hyponatremia
Study to Compare Conivaptan in Subjects With Mild & Moderate Liver Impairment Versus Subjects With Normal Liver Function
A study to compare a 48-hour continuous infusion of conivaptan in subjects with mild and moderate liver impairment versus subjects with normal liver function
- Trial name
- NCT00851227
- Testing
- conivaptan hydrochloride
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cumberland Pharmaceuticals
Patients With Impaired Hepatic Function
Pharmacokinetics Study in Patients With Impaired Hepatic Function
The objective of this study is to compare and evaluate the pharmacokinetics of ASP015K in patients with impaired hepatic function and subjects with normal hepatic function.
- Trial name
- NCT02586194
- Testing
- ASP015K
- Where
- 6 sites in Japan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Normal Tension Glaucoma
R&D of Non-invasive Innovative Intracranial Waves Monitoring System for Diagnostics and Treatment Monitoring of Patients with Normal Tension Glaucoma
Assessment and monitoring of intracranial pressure (ICP) changes are important in the management of cerebral pathologies. In the eye, ICP increase and decrease both correlate with optic neuropathies, the former because of…
- Trial name
- NCT06443411
- Testing
- Monitoring of cerebral hemodynamics
- Where
- Lithuania
- Volunteers
- 156 people
- Sponsor
- Lithuanian University of Health Sciences
Surgical Site Infections
Effect of Cefazolin and Normal Saline Irrigation on Surgical Site Infections (SSIs)
This study conducted to assess the effects of normal saline or cefazolin irrigation on the incidence of SSIs. Hypothesis: Normal saline or cefazolin irrigation decreases the incidence of SSIs.
- Trial name
- NCT01566734
- Testing
- Cefazolin irrigation, Normal Saline Irrigation
- Where
- Iran
- Volunteers
- 200 people
- Sponsor
- Hormozgan University of Medical Sciences
Vaginal Delivery, Normal Labor
Comparative Analysis of Analgesic Efficacy: by Single Shot Intrathecal Analgesia (SSSA) in Normal Labor
the goal of this randomized control trial is to compare the effect of adding fentanyl v.s dexmedetomidine to bupivacaine in single shot spinal analgesia in achievement of analgesia by decreasing visual analogue scale, onset and…
- Trial name
- SSSA (NCT06823349)
- Testing
- Dexmedetomidine, fentanyl, Saline 0.9%
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Jehan George Sadek
Healthy
The Effect of Celecoxib on the Antiplatelet Effect of Aspirin and Clopidogrel in Normal Volunteers
Background: The prevalence of arthritis which needs celecoxib prescription is high in patients with coronary artery disease. The main concern is that celecoxib would increase thrombogenicity by inhibiting the synthesis of…
- Trial name
- NCT00882388
- Testing
- aspirin, celecoxib, aspirin + celecoxib
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Breast Cancer, Shoulder
Morbidity After Diagnosis and Treatment of Breast Cancer Patients
This study will examine the frequency and severity of problems in women with breast cancer for 2 years following initial medical treatment, including: Physical impairments, such as loss of strength or flexibility, increased…
- Conditions
- Breast Cancer, Shoulder, Lymphedema, Fatigue
- Trial name
- NCT00027118
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Diabetes Mellitus, Type 2
A Study to Evaluate Safety, Tolerability and pK of Semaglutide ER Injectable Suspension in Healthy, Adult Human Subjects
The purpose of the trail is to evaluate the safety, tolerability and pharmacokinetics of a single escalated doses of semaglutide extended-release injectable suspension in healthy adult, human study participants under fasting…
- Trial name
- NCT06422624
- Testing
- Semaglutide Extended-release for Injectable Suspension, 1 mg, Semaglutide Extended-release for Injectable Suspension, 4 mg, Semaglutide Extended-release for Injectable Suspension, 8 mg
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bostal Drug Delivery Co., Ltd
Normal Physiology
Neurophysiology of Surround Inhibition in the Human Motor Cortex
Background: Movement disorders have many different causes and symptoms. Researchers still do not fully understand which parts of the brain are involved in fine movement.
- Trial name
- NCT03018262
- Testing
- TMS - sub-study 1, TMS - sub-study 2, TMS - sub-study 3
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Frontotemporal Lobar Degeneration, Alzheimer Disease
PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620
The investigators will compare [18F]-PI-2620 tau PET scans from patients with frontotemporal lobar degeneration (FTLD), patients with non-amnestic presentations of Alzheimer's disease (naAD), and demographically matched…
- Conditions
- Frontotemporal Lobar Degeneration, Alzheimer Disease, Cognitively Normal
- Trial name
- NCT05456503
- Testing
- [18F]-PI-2620
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Skin Cancer
In Vivo Confocal Microscopy of Cutaneous Neoplasms and Normal Skin
The purpose of this study is to investigate new non-invasive imaging techniques for the evaluation of skin lesions, as well as normal skin.
- Trial name
- NCT00588315
- Where
- 4 sites in United States
- Volunteers
- 1,889 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Brain Infarction
Normal Saline Infusion After Intravenous Thrombolysis in Stroke
The intravenous administration of abundant normal saline is an easy-to-use strategy commonly employed to expand the blood volume.
- Trial name
- NCT07497542
- Testing
- normal saline
- Where
- China
- Volunteers
- 752 people
- Sponsor
- Tianjin Medical University General Hospital
Postural Orthostatic Tachycardia Syndrome, Post Acute Sequelae of SARS CoV 2 Infection
NC Testing in LC & POTS
Patients with Postural Orthostatic Tachycardia Syndrome (POTS) and Post-Acute Sequelae of COVID (PASC, or "Long COVID") experience cognitive dysfunction.
- Trial name
- NCT05914649
- Testing
- IV normal saline (999 mL infusion), IV normal saline (50 mL infusion)
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Weight Loss, Obesity
A Study to Assess the Effect of a Normal vs. High Protein Diets in Carbohydrates Metabolism in Obese Subjects With Diabetes or Prediabetes
The objective of the study is to assess the effect of low-calorie diets with normal (18%) vs. high (35%) protein (mainly coming from animal source) composition on body weight and carbohydrates metabolism in overweight and obese…
- Conditions
- Weight Loss, Obesity, Diabetes, Diet, Reducing
- Trial name
- NCT02559479
- Testing
- Weight loss interventional study with a low-calorie 18%-protein diet, Weight loss interventional study with a low-calorie 35%-protein diet
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Instituto Aragones de Ciencias de la Salud
Normal Healthy Subjects With no Known Ocular Diseases
Retinal Fundus Camera Evaluation
Establish a normal baseline setting configuration for image capture using the Topcon TRC-NW400 non-mydriatic retinal camera.
- Trial name
- NCT02293174
- Testing
- Topcon TRC-NW400, TRC-NW8, TRC-NW400
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Topcon Medical Systems, Inc.
Healthy Volunteers
3-Way Crossover Study to Compare the PK (Pharmokinetics) and to Evaluate the Effect of Food on the Bioavailability
This is a single center, Phase 1, randomized, open-label, single-dose, 3 treatment, 3-period, 6-sequence, crossover study designed to compare the PK of SMP-100 dissolved in water for oral administration with SMP-100 tablets under…
- Trial name
- NCT05029518
- Testing
- SMP-100
- Where
- Australia
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Chengdu SciMount Pharmatech Co., Ltd.
Immune System Tolerance, Depression
ESAN II - Energy Sensing in Depression
The purpose of this study is to assess the effects of polyphenols from natural aronia juice on the immune system. Therefore, the study aims to distinguish the effects of natural juices that are rich in phytonutrients such as…
- Conditions
- Immune System Tolerance, Depression, Obesity, Microbial Colonization
- Trial name
- NCT05432362
- Testing
- Aronia Juice
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Ocular Tolerance, Skin Tolerance
A Clinical Study of Systane® Lid Wipes in Brazil
The purpose of this study is to verify the skin and ocular tolerance of the product Systane® Lid Wipes.
- Trial name
- NCT02380261
- Testing
- Systane® Lid Wipes
- Where
- Brazil
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Renal Impairment
Pharmacokinetics and Safety of ABT-493 and ABT-530 in Subjects With Normal and Impaired Renal Function
This is an open-label, single dose study designed to assess the pharmacokinetics and safety of ABT-493 and ABT-530 in subjects with either normal renal function or impaired renal function.
- Trial name
- NCT02442258
- Testing
- ABT-493, ABT-530
- Where
- 3 sites in United States, New Zealand
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- AbbVie
Schizophrenia
Comparison of Video Consent Versus Routine Consent for Participation in Research Studies
The purpose of this study is to examine a novel technique for improving the informed consent process for participation in research by the older psychiatric population.
- Trial name
- NCT00430391
- Testing
- DVD Consent, Routine Control
- Where
- United States
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego