Clinical trials: Normal Gait
GLAUCOMA 1, OPEN ANGLE, D (Disorder)
Spectral Domain Optical Coherence Tomography Analysis for Glaucoma
The aim of this study is to examine whether there is a difference in macular ganglion cell complex thickness and retinal nerve fiber layer thickness in early-stage Primary open angle glaucoma and normal tension glaucoma with…
- Trial name
- NCT01612416
- Testing
- RS-3000 OCT measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Inonu University
Suppression of Ovulation
A Dose-finding Study to Evaluate the Effect of a Contraceptive Vaginal Ring, Releasing Nestorone® and Estradiol, on Cycle Control, Ovulation Inhibition, and Pharmacokinetics in Normal Cycling Women
This clinical trial is an experimental research study using a potential new form of birth control. Clinical trials include people who volunteer to take part in a study.
- Trial name
- NCT01586000
- Testing
- 10 µg/day E2 with NES 200® µg/day, 20 µg/day E2 with NES 200® µg/day, 40 µg/day E2 with NES 200® µg/day
- Where
- 8 sites in United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Kimberly Myer
Retinal Ageing
Carotenoid Supplementation and Normal Ocular Health
Normal ageing affects vision as a result of preretinal and retinal changes. Photoreceptors, the light sensitive cells in the retina, degenerate and the rods (responsible for night vision) are most susceptible to damage with…
- Trial name
- NCT02147171
- Testing
- VisionAce
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Open-angle Glaucoma, Low Tension Glaucoma
Waveform Analysis of the Doppler Curve of Ophthalmic Arteries in Glaucoma Patients
Color Doppler Imaging (CDI) has been providing information about ocular blood flow over the past decades. This non-invasive procedure based on ultrasound technique has identified increased resistance and decreased systolic blood…
- Trial name
- NCT01487655
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Physical Activity, Heart Failure
WHISH-2-Prevent Heart Failure
The WHISH-2-Prevent Heart Failure (HF) study is an ancillary study to the Women's Health Initiative Strong and Healthy (WHISH) exercise pragmatic trial.
- Conditions
- Physical Activity, Heart Failure, Heart Failure With Reduced Ejection Fraction, Heart Failure With Normal Ejection Fraction
- Trial name
- NCT03099889
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 49,936 people, healthy volunteers welcome
- Sponsor
- Memorial Hospital of Rhode Island
Eating Behavior
The Effect of Food Hedonics on Appetite Hormones Levels
30-40 healthy male subjects with a BMI between 18.5 and 24.9 kg/m2 will be tested for food preferences using a questionnaire with 141 different foods.
- Trial name
- NCT02615613
- Testing
- Low Acceptability Meal, High acceptability meal
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Gingivitis, Periodontitis
Application of Ultra-high Frequency Ultrasonography (UHFUS) to the Study of Gingival Tissues
Gingival inflammation triggered by the accumulation of bacterial is the primary risk factor for the development of periodontitis.
- Trial name
- NCT06480825
- Testing
- Performance of ultrasonographic scan
- Where
- 2 sites in Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Carbon Monoxide Poisoning
Normal Quantitative EEG (qEEG) Dataset
In this study, the investigators will collect EEG data in normal, healthy volunteers without a history of prior brain injury. This data will be analyzed by computer (quantitative, or qEEG) and stored in a normative database so…
- Trial name
- NormalEEG (NCT02375126)
- Testing
- Electroencephalography
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Intermountain Health Care, Inc.
Acute Kidney Injury
Pharmacokinetics of MB-102 and Use of the Non-invasive Optical Renal Function Monitor (ORFM) Device in Subjects With Normal and Impaired Renal Function and a Range of Skin Color Types
This study was a pilot, safety, and pharmacokinetic study of MB-102 versus iohexol and the use of the non-invasive optical renal function monitor (ORFM) device in normal and compromised renal function participants with different…
- Trial name
- NCT02772276
- Testing
- MB-102-- single dose of 4 µmol/kg, MB-102-- single dose of 130 mg, MB-102-single dose of 130 mg or 2 doses of 130 mg 12 hours apart
- Where
- 3 sites in United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- MediBeacon
Right Ventricular Hypertrophy, d-TGA
Right Ventricular Hypertrophy After Atrial Switch and Cardiovascular Magnetic Resonance (CMR) Findings
Systemic RV hypertrophy and impaired systolic function occur after atrial switch (AS) in d-transposition of the great arteries (d-TGA). Echocardiography has limitation in the assessment of the right ventricle (RV).
- Trial name
- NCT01430897
- Where
- Germany
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Radiotracer, Hypertension
Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Groups 2, 3 & 4)
This study will evaluate the feasibility of using a sub-therapeutic dose of a fluorine-18 analogue of NP-59 ([18F]FNP-59) to image the adrenal gland.
- Conditions
- Radiotracer, Hypertension, Cholesterol
- Trial name
- NCT04546126
- Testing
- Dexamethasone (Group 2), Cosyntropin (Group 3), PET/CT Scan with FNP-59
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Benjamin Viglianti
Age-Related Macular Degeneration
A Pilot Study of the Safety of MC-1101 in Both Normal Volunteers and Patients With Early Dry AMD
The safety and comfort of repeated administrations of a topically-administered ophthalmic formulation of MC-1101 will be established through investigator assessments and subject reporting over a 3 day period.
- Trial name
- NCT01013376
- Testing
- MC-1101, Vehicle
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- MacuCLEAR, Inc.
Heart Failure, Obesity
Fatty Acid Radiotracer Comparison Study in Heart Failure Patients
A single center, open-label baseline controlled imaging study to designed to assess whether Positron Emission Tomography (PET) measurements of myocardial Fatty Acid (FA) metabolism performed with [18F]FluorbetaOx correlates with…
- Conditions
- Heart Failure, Obesity, Type 2 Diabetes Mellitus, Health Normal Volunteer Subjects
- Trial name
- NCT01648296
- Testing
- [18F]FluorbetaOx
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Normal Skin
TMFI Enhances Skin Surface and Epidermal PpIX Fluorescence
This study investigates a relatively new device TMFI and incubation of ALA in a cream-vehicle and a gel-vehicle.
- Trial name
- NCT04221126
- Testing
- TMFI, ALA cream, ALA gel
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Merete Haedersdal
Overweight, Obesity
Exercise Genes: Genomic Association With Exercise Reinforcement
This study tests whether different physical activity patterns are linked an individual's genes.
- Conditions
- Overweight, Obesity, Physical Activity
- Trial name
- ExGenes (NCT02416882)
- Testing
- Aerobic Exercise, Resistance Exercise, Sedentary Option
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Hepatic Impairment
MEK162 in Healthy Subjects With Normal Hepatic Function and Subjects With Impaired Hepatic Function
This study is a phase I, multi-center, open-label, single oral dose, parallel group study to assess the PK and safety of MEK162 in subjects with impaired hepatic function and healthy subjects with normal hepatic function.
- Trial name
- MEK162 (NCT02050815)
- Testing
- MEK162
- Where
- 5 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Array Biopharma, now a wholly owned subsidiary of Pfizer
Infertility
Influence of a Prematuration Culture With a Phosphodiesterase-3 Inhibitor (PDE3-I) on Embryonic Aneuploidy Rate and Developmental Potential
A single centre randomised controlled trial investigating the influence of a novel prematuration system (PMS) using a phosphodiesterase-3 inhibitor for in-vitro maturation of oocytes
- Trial name
- NCT00823420
- Testing
- prematuration culture
- Where
- Belgium
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Healthy, Schizophrenia
Eye Blink Response in Healthy Volunteers and Adults With Schizophrenia
The purpose of this study is to explore how the brain works during particular memory tasks in people with schizophrenia and healthy volunteers.
- Trial name
- NCT00001920
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Healthy Volunteers
Bioequivalence Study of Tacrolimus 5 mg Capsule Under Fasting Condition
The objective of the study is to demonstrate bioequivalence between Test Product (A): Tacrolimus Capsules 5 mg, manufactured by Panacea Biotec Limited, India and the corresponding Reference Product (B): Prograf (Tacrolimus)…
- Trial name
- NCT01080482
- Testing
- Tacrolimus 5 mg Capsule
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Panacea Biotec Ltd
Dyspepsia
Gastric Motor Function Measurement in Dyspepsia and Normal Subjects
This study is being done to measure the functions of the stomach after eating a meal and to develop a new method that will simultaneously measure both gastric emptying and the relaxation of the stomach after a meal using nuclear…
- Trial name
- NCT00296582
- Testing
- Gastric Motor Function Measurement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
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