Clinical trials: Nonsuicidal Self-Injury, open to volunteers
Nonsuicidal Self Injury, Emotion Regulation
Neuro- and Biofeedback in Nonsuicidal Self-injury
Nonsuicidal self-injury (NSSI) is defined as the direct, deliberate destruction of one's own body tissue without suicidal intent, typically including behaviors such as cutting, burning, or hitting oneself.
- Trial name
- NCT05656001
- Testing
- Real-time functional magnetic resonance imaging Neurofeedback and Real-time Biofeedback
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Östergötland
Self Injurious Behavior, Self Injurious Behavior Without Suicidal Intent
Examining the Effectiveness of a Brief Therapeutic Intervention for Reducing Self-Harm Among Adolescents
Non-suicidal self-injury (NSSI), defined as deliberate self-inflicted destruction of body tissue without intent to die, is particularly prevalent during mid-adolescence, with prevalence estimated around 16-22% in community…
- Trial name
- NCT07913425
- Testing
- Cutting Down Program - a three-month cognitive-behavioral psychotherapy focused on reducing self-injury urges and behaviors in adolescents
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- University of Haifa
Depression
A Study on the Intervention Effect of Therapeutic Horticulture Based on the Healing System on Non-suicidal Self-injury in Adolescent Patients With Depression
Non-suicidal self-harm is a serious issue. Adolescents with depression are among the high-risk groups for non-suicidal self-harm behavior.
- Trial name
- NCT07115381
- Testing
- Therapeutic Horticulture, Routine treatment and nursing
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Lei Huang
Psychiatric Disorder
Pilot Study on the Acceptability of Auricular Vagus Nerve Neurostimulation in Adolescents
Non-suicidal self-injury (NSSI) are acts defined by the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders 5) as intentional and deliberate, occurring outside a psychotic state and directly causing moderate injury.
- Trial name
- NEUROMUTE (NCT06433583)
- Testing
- transcutaneous auricular vagal nerve stimulation
- Where
- 2 sites in France
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Nonsuicidal Self Injury, Emotion Regulation
Emotion Regulation Dysfunctions in NSSI Adolescents in Naturalistic Contexts
Nonsuicidal self-injury (NSSI) is defined as direct, deliberate bodily harm without suicidal intention. Recent studies indicate that prevalence rates are increasing worldwide, in particular under adolescents, indicating a growing…
- Trial name
- NCT05907421
- Testing
- Acceptance mindset
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Caregivers, Suicide
A Pilot Study of a DBT-Informed Caregiver Risk Management Workshop
The goal of this pilot clinical trial is to explore the feasibility and acceptability of implementing an intervention for caregivers in our health care system.
- Conditions
- Caregivers, Suicide, Nonsuicidal Self Injury, Adolescent
- Trial name
- NCT07852429
- Testing
- Workshop and consultation for caregivers of at risk youth
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Nonsuicidal Self Injury, Risk-Taking
Social Feedback and Dysfunctional Risk Taking in NSSI Adolescents
Nonsuicidal self-injury (NSSI) is defined as direct, intentional physical injury without suicidal intention. Problematic interpersonal relationships and decision-making have been demonstrated to play crucial roles in this…
- Trial name
- NCT05981677
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Self-harm, Personality Disorder, Borderline
Self-harm Behaviour Among the Most At-risk Adolescents
In the proposed study, three objectives will be pursued: 1. To develop a method to identify more effectively the acute and long-term risk of adolescents with the most threatening self-harm behaviours. 2.
- Conditions
- Self-harm, Personality Disorder, Borderline, Epigenetic Disorder, Non-Suicidal Self Injury
- Trial name
- SH-MARA (NCT05765864)
- Testing
- Enrollment questionnaire, General questionnaire1, General questionnaire2, General questionnaire3, Columbia Suicide Severity Rating Scale (CSSRS), The Brief Non-Suicidal Self-Injury Assessment Tool (B-NSSI-AT)
- Where
- 2 sites in Slovenia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana, Faculty of Medicine
Nonsuicidal Self Injury, Nonsuicidal Self-Injury
Psychological Treatment for Adolescents With Self-injury Within Intensive Mental Health Outpatient Services: Randomized Controlled Pilot Trial
The overarching aim of this study is to develop and evaluate a new blended treatment format, which combines face-to-face and digital treatment components, for Emotion Regulation Individual Therapy for Adolescents (ERITA).
- Conditions
- Nonsuicidal Self Injury, Nonsuicidal Self-Injury, Self-Harm
- Trial name
- NCT07755774
- Testing
- Blended ERITA, Treatment as Usual (TAU), Concomitant care
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Non-suicidal Self-injury (NSSI)
Non-Suicidal Self-Injury Digital Psychotherapy Trial
The goal of this randomized, parallel-controlled clinical trial is to investigate multi-dimensional biomarkers (blood, brain imaging, clinical information, and symptom assessment) in adolescents with Non-Suicidal Self-Injury…
- Trial name
- NSSI-DPT (NCT07683234)
- Testing
- digital psychotherapy, Treatment as Usual (TAU)
- Volunteers
- 110 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Aggressive Behavior in Fragile X Syndome
Inhibition of Aggressive Behavior in Participants With Fragile X Syndrome
The goal of this clinical trial is to learn if drug SRX246 works to treat irritability, agitation, aggression and self-injury (IAAS) behaviors in adult males with Fragile X Syndrome (FXS).
- Trial name
- NCT07328529
- Testing
- SRX246
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Azevan Pharmaceuticals
Nonsuicidal Self-Injury
Trial to Evaluate the Effects of Naltrexone in Nonsuicidal Self-injury
The goal of this clinical trial is to learn if naltrexone works to treat nonsuicidal self-injurious behavior in adolescents and adults.
- Trial name
- NiNsSIB (NCT06622239)
- Testing
- Naltrexone
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Hospital
Depression Disorders, Non-suicidal Self-injury
The Impact of Beta-band Transcranial Alternating Current Stimulation (tACS) on Impulse Inhibition in Adolescents With Non-suicidal Self-injury
This clinical trial aims to determine whether beta-band transcranial alternating current stimulation (tACS) can improve impulse inhibition in adolescents with non-suicidal self-injury (NSSI) and to evaluate its safety.
- Trial name
- NCT07152925
- Testing
- Beta-frequency transcranial alternating current stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
NSSI
Effects of Repetitive Transcrannial Magnetic Stimulation on Non-Suicidal Self-Injury
Non-suicidal self-injury (NSSI) refers to a series of direct and consequently repeated injuries to one's body without suicidal intent. At present, it has become an important issue of mental disorders.
- Trial name
- NCT06540300
- Testing
- rTMS stimulation of left M1
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Nanjing Medical University
Non-suicidal Self-injury (NSSI), Adolescent
Neurobiological Markers of Non-suicidal Self-injury and Treatment Mechanisms of Adolescent Self-injury Intervention Skills Training
The goal of this clinical trial is to evaluate the effectiveness and safety of Adolescent Self-Injury Intervention Skills Training (ASIST), a treatment program developed by the research team, compared with treatment as usual…
- Trial name
- ASIST (NCT07910110)
- Testing
- Adolescent Self-Injury Intervention Skills Training (ASIST), Treatment as Usual (TAU)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University
Self-harm Behavior, Eating Disorders
Evaluation of National Highly Specialized Care for Children and Adolescents With Severe Self-Harm or Eating Disorders
National Highly Specialized Care (NHV) is provided in Sweden to children and adolescents with severe and treatment-resistant self-harm or eating disorders when previous treatment has not led to sufficient improvement.
- Conditions
- Self-harm Behavior, Eating Disorders, Non-suicidal Self-injury (NSSI)
- Trial name
- NHV_CHILD (NCT07898059)
- Testing
- National Highly Specialized Care (NHV)
- Where
- 2 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Karolinska Institutet
Self-injury, Suicidal Ideation and Behavior
Pilot Trial of an Emotion Regulation and Executive Functioning Intervention for Self-Injurious Thoughts and Behaviors (SITBs) in Children
The goal of this study is to develop and test an outpatient intervention for preadolescents (ages 7-12) with self-injurious thoughts and behaviors (SITBs). The main questions it aims to answer are: 1.
- Conditions
- Self-injury, Suicidal Ideation and Behavior, Executive Functioning, Emotion Regulation
- Trial name
- NCT07281365
- Testing
- Treatment as usual (TAU), Preadolescent SITB Intervention
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Colorado, Denver
Self-Harm, Self-Harm, Deliberate
Group Treatment for Self-harming Adolescents and Their Parents: a Randomized Controlled Trial
Adolescent non-suicidal self-injury (NSSI) is common, strongly associated with psychiatric comorbidity and an increased risk of future suicide attempt.
- Conditions
- Self-Harm, Self-Harm, Deliberate, Self-harm Behavior, Non-Suicidal Self Injury
- Trial name
- ERA (NCT07720063)
- Testing
- Emotion Regulation Group Therapy for Self-harming Adolescents, ERA, Functional habits for mental health, FUNK
- Volunteers
- 180 people
- Sponsor
- Karolinska Institutet
Temporal Interference Stimulation, Non Suicidal Self Injury
TIS for NSSI in Adolescent Depression
Temporal Interference Stimulation (TIS) has been successfully used to help patients with depression. However, its role in alleviating self injuries remained uncertain.
- Conditions
- Temporal Interference Stimulation, Non Suicidal Self Injury, Major Depressive Disorder
- Trial name
- NCT07554755
- Testing
- Active Temporal Interference Stimulation (TIS)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Second Hospital of Anhui Medical University
Non-suicidal Self-injury (NSSI)
Acceptance and Commitment Therapy-Based Chatbot for Non-suicidal Self-Injury in Adolescents
The purpose of this study is to evaluate the feasibility and effectiveness of a self-guided digital Acceptance and Commitment Therapy (ACT) intervention for adolescents who engage in non-suicidal self-injury (NSSI).
- Trial name
- NCT07848620
- Testing
- ACT-Based Chatbot
- Volunteers
- 100 people
- Sponsor
- Central China Normal University