Clinical trials: Nonsuicidal Self-Injury
Self-Harm, Deliberate, Non-Suicidal Self Injury
Aspects of Self-harm - Cognition, Imaging and Treatability
Deliberate self-harm (DSH) is a common symptom in psychiatric disorders. This study aim at increased understanding of parameters associated with DSH with the long term goal to potentially improve and possibly personalise its…
- Conditions
- Self-Harm, Deliberate, Non-Suicidal Self Injury, Attempt Suicide, Personality Disorders
- Trial name
- NCT04905797
- Testing
- Emotional Stop Signal Task, Magnetic Resonance Imaging, World Health Organizations Disability Assessment Schedule (WHODAS 2.0)
- Where
- Sweden
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Region Skane
Non-suicidal Self-injury (NSSI)
Blended Unified Protocol for Chinese Adolescents With Non-Suicidal Self-Injury: A Randomized Controlled Trial
This study is an open-label, randomized controlled trial evaluating the efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Adolescents (UP-A) in reducing non-suicidal self-injury (NSSI) among…
- Trial name
- NCT07110181
- Testing
- a blended version of the Unified Protocol for Adolescents (UP-A), Standard psychiatric treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jian-Jun Ou
Self-Harm, Self-harm Behavior
Self-harm and the Prison Environment Mixed Methods Study
Self-harming behaviour is a major problem in UK prisons: the number of self-harm incidents has more than doubled over the past decade. People who self-harm in prison are at greater risk of subsequent death by suicide.
- Conditions
- Self-Harm, Self-harm Behavior, Self-Harm, Deliberate
- Trial name
- SHAPE (NCT06895668)
- Testing
- None (cohort study)
- Volunteers
- 458 people, healthy volunteers welcome
- Sponsor
- King's College London
Problem Behavior, Aggression
Basic and Applied Research on Extinction Bursts
Although highly effective, treatments like FCT include extinction, which can have adverse side effects. The extinction burst, an increase in the frequency or intensity of destructive behavior at the start of treatment, is the…
- Conditions
- Problem Behavior, Aggression, Self Injury
- Trial name
- NCT05925101
- Testing
- Extinction-only condition, Rate-drop condition, Rate-hold condition
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Borderline Personality Disorder, Suicide
Comparing Treatments for Self-Injury and Suicidal Behavior in People With Borderline Personality Disorder
This study will compare the effectiveness of two treatments, dialectical behavior therapy versus fluoxetine with clinical management, for reducing the risk of self-injury and suicidal behavior in people with borderline…
- Trial name
- NCT00834834
- Testing
- Fluoxetine, DBT, Citalopram
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- New York State Psychiatric Institute
Non-Suicidal Self Injury
A Case-Series Examination of a Brief CAT-Informed Intervention (CATCH-Y) for Young People That Have Self-Injured
Non-suicidal self-injury (NSSI), the term used for when somebody purposefully hurts themselves without intending to end their life. Often, it suggests that there are other difficulties going on in someone's life.
- Trial name
- CATCHY (NCT04708262)
- Testing
- Cognitive Analytic Therapy for Containing Self-Harm in Young People
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- University of Manchester
Nonsuicidal Self Injury, Stigmatization
Scar Resection and Reconstruction With Integra and Split Skin Grafts in Patients With Non-Suicidal Self-Inflicted Scars
Non-suicidal self-inflicted (NSSI) scars can act as a physical reminder of previous self-inflicted self-harm, thereby not only worsening the symptoms of depression and self-doubt but also leading to recurrent self-infliction and…
- Conditions
- Nonsuicidal Self Injury, Stigmatization, Cicatrix, Skin Transplantations
- Trial name
- NCT04420442
- Testing
- Scar Transformation Group
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Berufsgenossenschaftliche Unfallklinik Ludwigshafen
Adolescent - Emotional Problem, Adolescent Problem Behavior
Treating Self-criticism in Adolescents: a Study With Single-case Experimental Design
In this pilot study, the effect of a group intervention targeting self-criticism in adolescents in a clinical child- and adolescent psychiatric outpatient setting will be examined using a single-case experimental design (AB).
- Conditions
- Adolescent - Emotional Problem, Adolescent Problem Behavior, Nonsuicidal Self Injury, Depressive Symptoms
- Trial name
- NCT05247190
- Testing
- Treating self-criticism
- Where
- Sweden
- Volunteers
- 19 people
- Sponsor
- Region Östergötland
Transcranial Alternating Current Stimulation, Non-suicidal Self-injury
Intervention Effect of High-Definition Transcranial Alternating Current Stimulation (HD-tACS) on Non-suicidal Self-injury (NSSI)
To investigate the intervention effect of high-definition transcranial alternating current stimulation (HD-tACS) on patients with Non-suicidal Self-injury (NSSI) and its underlying neural mechanism by magnetic resonance imaging…
- Trial name
- NCT06127056
- Testing
- High-Definition Transcranial Alternating Current Stimulation (HD-tACS)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Depression, Self-injurious Behavior
Interpersonal Psychotherapy for Depressed Adolescents Engaging in Non-suicidal Self-injury
The purpose of this study is to examine the feasibility of using Interpersonal Psychotherapy for Depressed Adolescents (IPT-A) to treat adolescents who are experiencing symptoms of depression and are engaging in non-suicidal…
- Trial name
- IPT-ASI (NCT00401102)
- Testing
- Interpersonal Psychotherapy for Depressed Adolescents
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New York State Psychiatric Institute
Nonsuicidal Self-Injury, Self-Harm
Internet-delivered Emotion Regulation Individual Therapy or Adolescents (IERITA) With Self-injury Within Child and Adolescent Mental Health Services: Pilot Study
The overall purpose of the study is to implement and evaluate IERITA (Internet-delivered Emotion Regulation Individual Therapy for Adolescents) within child and adolescent mental health services for adolescents engaging in…
- Trial name
- NCT06817278
- Testing
- Adaptable IERITA, Standard IERITA, Treatment as usual
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Depression
A Study on the Intervention Effect of Therapeutic Horticulture Based on the Healing System on Non-suicidal Self-injury in Adolescent Patients With Depression
Non-suicidal self-harm is a serious issue. Adolescents with depression are among the high-risk groups for non-suicidal self-harm behavior.
- Trial name
- NCT07115381
- Testing
- Therapeutic Horticulture, Routine treatment and nursing
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Lei Huang
Nonsuicidal Self-Injury, Self-Injurious Behavior
Naltrexone for Nonsuicidal Self-Injury
This randomized, double-blinded, placebo-controlled clinical trial aims to evaluate the efficacy and safety of naltrexone in reducing nonsuicidal self-injurious behavior among individuals with nonsuicidal self-injury.
- Trial name
- NCT07641283
- Testing
- Naltrexone 50mg (Whanin Naltrexone Tab. 50mg)
- Where
- 3 sites in South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Hospital
Borderline Personality Disorder, Self-harm
Effects of Psychiatric Admissions on Self-harm and Suicide in People With Borderline Personality Disorder
The current study aims to evaluate the impact of long (>5 days) and/or compulsory psychiatric inpatient care on subsequent healthcare utilization for self-harm and suicide in people with borderline personality disorder, a…
- Conditions
- Borderline Personality Disorder, Self-harm, Non-suicidal Self-injury, Suicide
- Trial name
- NCT06424509
- Testing
- High degree of long (>5 days) and/or compulsory psychiatric inpatient care
- Where
- Sweden
- Volunteers
- 390 people
- Sponsor
- Lund University
Nonsuicidal Self Injury, Prediction Errors
Impact of Emotional Reactivity on Dysfunctional Decision-Making in NSSI Adolescents
Nonsuicidal self-injury (NSSI) is defined as direct, intentional physical injury without suicidal intention. Studies revealed that dysfunctional interpersonal relationships and reward-related decision-making may play crucial…
- Trial name
- NCT05981612
- Where
- China
- Volunteers
- 80 people
- Sponsor
- University of Electronic Science and Technology of China
NSSI
Effects of Repetitive Transcrannial Magnetic Stimulation on Non-Suicidal Self-Injury
Non-suicidal self-injury (NSSI) refers to a series of direct and consequently repeated injuries to one's body without suicidal intent. At present, it has become an important issue of mental disorders.
- Trial name
- NCT06540300
- Testing
- rTMS stimulation of left M1
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Nanjing Medical University
Nonsuicidal Self Injury, Risk-Taking
Social Feedback and Dysfunctional Risk Taking in NSSI Adolescents
Nonsuicidal self-injury (NSSI) is defined as direct, intentional physical injury without suicidal intention. Problematic interpersonal relationships and decision-making have been demonstrated to play crucial roles in this…
- Trial name
- NCT05981677
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Non-Suicidal Self Injury, Suicide
Dialectical Behavioral Therapy in Juvenile Justice
Self-injurious thoughts and behaviors (SITBs) are a serious public health concern, particularly for youth involved in the juvenile justice system (JJS), which the Georgia State Juvenile Justice System (GAJJS) intends to address…
- Conditions
- Non-Suicidal Self Injury, Suicide, Self-harm, Emotion Regulation
- Trial name
- DBT-A&JJS (NCT05583279)
- Testing
- Dialetical Behavioral Therapy for Adolescents
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Catholic University of America
Non-suicidal Self-injury
Research on the Intervention of VR-based Emotion Regulation Technology on Adolescent Non-suicide Self-injury Behavior
Non suicidal self injury (NSSI) has become a serious social and public health problem allover the world, and the incidence rate is increasing year by year.
- Trial name
- VR (NCT05734872)
- Testing
- Virtual Reality Technology, Routine mental health course training
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Caregivers, Suicide
A Pilot Study of a DBT-Informed Caregiver Risk Management Workshop
The goal of this pilot clinical trial is to explore the feasibility and acceptability of implementing an intervention for caregivers in our health care system.
- Conditions
- Caregivers, Suicide, Nonsuicidal Self Injury, Adolescent
- Trial name
- NCT07852429
- Testing
- Workshop and consultation for caregivers of at risk youth
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco