Clinical trials: Noncommunicable Diseases
Breast Cancer, Cardiovascular (CV) Risk
Multicenter Cardiac Decision Impact Study in People With Breast Cancer
Background: Breast cancer is the most common cancer in women, and advances in early detection and treatment have led to steadily improved survival rates. Today, nearly 80% of breast cancer survivors are over 50 years of age.
- Conditions
- Breast Cancer, Cardiovascular (CV) Risk, Coronary Artery Calcifications
- Trial name
- CarDI (NCT07703033)
- Testing
- Measuring coronary artery calcifications (Agatston score) using routine radiotherapy planning CT scans and communicating the associated risk of cardiovascular disease to the patient.
- Where
- 5 sites in Denmark, Germany and 2 more
- Volunteers
- 1,000 people
- Sponsor
- UMC Utrecht
Non-Communicable Chronic Diseases
Prevalence of NCD Risk Factors in Kazakhstan
This is a cross-sectional study that aims to study the prevalence of risk factors of noncommunicable diseases in people aged 18 to 69 years using the standardized and adopted STEPS questionnaire in the Republic of Kazakhstan.
- Trial name
- NCT05122832
- Testing
- Blood test, STEPwise Approach to NCD Risk Factor Surveillance (STEPS), Spirometry
- Where
- Kazakhstan
- Volunteers
- 20,400 people
- Sponsor
- Asfendiyarov Kazakh National Medical University
Non Communicable Diseases, Health-risk Behaviours
Prevent Non-communicable Diseases Through Screening and Educating Emergency Department Attendees to Adopt Healthy Lifestyles
Objective: To examine the effectiveness of a general health promotion intervention based on self-determination theory in proactively helping emergency department (ED) attendees to adopt healthy lifestyles.
- Trial name
- NCT06889792
- Testing
- Theory of planned behaviour, Foot-in-the-door technique, Self-determination theory
- Where
- Hong Kong
- Volunteers
- 1,172 people
- Sponsor
- Chinese University of Hong Kong
Hypertension (HTN), Diabetes
Evaluation of a New Virtual Care Pathway for Older Adults With Noncommunicable Diseases
The purpose of this study is to evaluate a newly developed virtual care program for older adults with chronic diseases (hypertension, diabetes and lipid disorders) whether it is feasible and economical to implement in the…
- Conditions
- Hypertension (HTN), Diabetes, Dyslipidaemia
- Trial name
- TeleCOOP-NCD (NCT07843238)
- Testing
- Teleconsultation care pathway for older adults with NCDs (TeleCOOP-NCD©)
- Where
- Malaysia
- Volunteers
- 160 people
- Sponsor
- National University of Malaysia
Chronic Kidney Diseases, Non-Communicable Chronic Diseases
Understanding Risk Factors for Progressive Chronic Kidney Disease in Malawi
Worldwide, the number of people living with long-term health conditions, including chronic kidney disease (CKD), is increasing. CKD is usually asymptomatic in early stages but can progress to advanced disease, including kidney…
- Conditions
- Chronic Kidney Diseases, Non-Communicable Chronic Diseases, Non-communicable Disease, Kidney Diseases
- Trial name
- NCT06312072
- Testing
- No intervention; observational study
- Where
- Malawi
- Volunteers
- 1,100 people
- Sponsor
- Liverpool School of Tropical Medicine
HIV, Non Communicable Diseases
Effects of a Package of Evidence-based Interventions and Implementation Strategies Based on WHO PEN for People Living With HIV and Cardio-metabolic Conditions in Lusaka, Zambia
The purpose of this study is to evaluate the effects of a multi-level intervention known as "TASKPEN," adapted from the World Health Organization (WHO) Package of Essential Noncommunicable Disease Interventions (WHO-PEN) for the…
- Trial name
- TASKPEN UH3 (NCT05950919)
- Testing
- TASKPEN
- Where
- 12 sites in Zambia
- Volunteers
- 5,747 people
- Sponsor
- University of North Carolina, Chapel Hill
Noncommunicable Disease, Infections
Rural South and Southeast Asia Household Health Survey
A cross-sectional household survey with two-stage cluster-randomized sampling. This cross-sectional household survey design to recruit a random sample of households that is representative for each of the study sites.
- Conditions
- Noncommunicable Disease, Infections, Risk Factors, Health Status
- Trial name
- SEACTN-HHS (NCT05389540)
- Where
- 4 sites in Bangladesh, Burma and 2 more
- Volunteers
- 4,747 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Diabetes Mellitus (Type 2), Prediabetes
Evaluation of the Effectiveness of Implementing a Screening Strategy for the Diagnosis of Prediabetes and Type 2 Diabetes Mellitus in Primary Health Care in a Brazilian Municipality
Primary objective: To evaluate the effectiveness of the ARISE strategy on the proportion of individuals with confirmed T2DM diagnosis, per protocol criteria based on the PCDT-DM2 (Clinical Protocol and Therapeutic Guidelines for…
- Trial name
- ARISE (NCT07846319)
- Testing
- ARISE Strategy
- Where
- 2 sites in Brazil
- Volunteers
- 45,000 people, healthy volunteers welcome
- Sponsor
- epHealth
Cardiovascular Diseases, Stroke
Cohort in Qianwan New District, Ningbo
Our objective is to carry out research on prevention and control of noncommunicable chronic diseases, and establish a risk prediction mechanism for chronic diseases to promote early detection, early diagnosis and early treatment…
- Conditions
- Cardiovascular Diseases, Stroke, Non-Communicable Chronic Diseases
- Trial name
- NCT06387875
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Diabetes, Hypertension
The Use of a Community-based Organization to Change Lifestyle Characteristics Related to Non Communicable Diseases
This study attempts to implement a lifestyle intervention programme aimed at changing the dietary habits, physical activity and alcohol and tobacco consumption in the 25-60year old adults in the MOH area, Ragama and measure the…
- Conditions
- Diabetes, Hypertension, Stroke, Ischemic Heart Disease
- Trial name
- NCT01174381
- Testing
- lifestyle modification
- Where
- Sri Lanka
- Volunteers
- 440 people
- Sponsor
- University of Kelaniya
Type 2 Diabetes Mellitus (T2DM)
Effect of Tai Chi Versus Moderate-intensity Combined Exercise Training on Cardiovascular Health and Physical Functional Performance in Older Men and Women With T2DM: the Tai Chi Intervention for Diabetes Management During Aging (TIDA) Study
This randomized, single-blind, controlled clinical trial compares the effects of a 12-week Tai Chi program versus moderate-intensity combined exercise (MICE) training on cardiovascular health, glycemic control, and physical…
- Trial name
- TIDA (NCT07131761)
- Testing
- Tai chi, Moderate-Intensity Combined Exercise (MICE), Control ( No Exercise )
- Volunteers
- 66 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Chronic Non-communicable Disease
Risk Factors at Chronic Non-communicable Diseases in People of Working Age
Objectives: to study the clinical and demographic characteristics of working age persons, to highlight the main factors of non-communicable diseases (NCDs), to identify NCDs with physical examination, laboratory tests…
- Trial name
- FORTUNE (NCT06812767)
- Testing
- electrocardiography, analysis for glucose and cholesterol in the capillary blood, detection of microalbumuria
- Where
- Russia
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Parkinson Disease (PD), Chronic Heart Failure (CHF)
An Innovative Disease-net Management Model for Non-communicable Diseases (SIDERA^B)
The SIDERA^B telerehabilitation system is enabled by a multi-domain, multi-device platform providing at home multi-component rehabilitation, targeting cardiovascular (Chronic Heart Failure, CHF), pulmonary (Chronic Obstructive…
- Conditions
- Parkinson Disease (PD), Chronic Heart Failure (CHF), Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- SIDERA^B (NCT04041193)
- Testing
- SIDERA^B, Usual Care Program
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Non-communicable Diseases (NCD)
Enabling Environments for Non-communicable Disease Risk Reduction in Ethiopia
The ENABLE study focuses on pregnant women attending routine antenatal care (ANC) in urban primary health care facilities in four Ethiopian cities.
- Trial name
- ENABLE (NCT07442318)
- Testing
- Structured lifestyle counseling integrated into ANC, Standard routine ANC
- Where
- 4 sites in Ethiopia
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Health-risk Behaviours, Non Communicable Diseases
Screening and Educating Emergency Department Attendees on Health-risk Behaviours
Aim: To determine the feasibility and potential efficacy of a proactive approach using a brief self-determination theory-based intervention to help people attending the ED modify their health-risk behaviours and lead healthier…
- Trial name
- NCT05680519
- Testing
- theory of planned behaviour, foot-in-the-door technique, and self-determination theory intervention, Control group
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- Chinese University of Hong Kong
Non-Communicable Diseases, Stroke
Make my Day - Primary Prevention of Stroke
The purpose of this study is to evaluate the feasibility of a digital, person-centered stroke prevention program with a focus on primary prevention.
- Conditions
- Non-Communicable Diseases, Stroke, Cardiovascular Risk Factor
- Trial name
- NCT03730701
- Testing
- Prevention program for stroke
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Emelie Malstam
Health Behavior, Noncommunicable Diseases
The LvL UP Pilot Trial
Non-communicable diseases (NCDs), such as cardiovascular disease, diabetes, or cancer, and common mental disorders (CMDs), such as depression or anxiety, represent the primary causes of death and disability worldwide, causing…
- Conditions
- Health Behavior, Noncommunicable Diseases, Mental Health Issue, Lifestyle Risk Reduction
- Trial name
- NCT06360029
- Testing
- LvL UP, LvL UP + MI, Comparison
- Where
- 2 sites in Singapore
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Singapore ETH Centre
Smoking Cessation
Effect of Vernonia Cinerea Lozenges as a Smoking Cessation Aid in Patients With Non-communicable Diseases
Vernonia cinerea is an herbal which has been recorded in many Thai herbal formulation and Thai traditional medicine has used this herbal for treating various diseases included hypertension, asthma, fever, hepatitis, kidney stone…
- Trial name
- NCT06268002
- Testing
- Vernonia cinerea
- Where
- Thailand
- Volunteers
- 93 people
- Sponsor
- Chulalongkorn University
Obesity, Overweight
Targeting DNA-methylation Fingerprints Linked to Ultra-Processed Foods Consumption to Prevent Non-communicable Diseases: the METHYL-UP Study
Non-communicable diseases (NCD) are the main health challenge in industrialized countries. However, these diseases are preventable if an intervention based on lifestyle is implemented at the population level.
- Trial name
- METHYL-UP (NCT05319327)
- Testing
- Nutritional intervention, Control
- Where
- Spain
- Volunteers
- 33 people
- Sponsor
- IMDEA Food
Arterial Hypertension, Atherosclerosis Occlusive Disease
Gut Microbiota in Chronic Noncommunicable Diseases
It is an observational study in patients with chronic noncommunicable diseases (i.e. cardiovascular diseases, diabetes mellitus, non-alcoholic fatty liver disease, chronic obstructive pulmonary disease and asthma ) and control…
- Conditions
- Arterial Hypertension, Atherosclerosis Occlusive Disease, Heart Failure With Preserved Ejection Fraction, Heart Failure With Reduced Ejection Fraction
- Trial name
- NCT04820556
- Where
- 2 sites in Russia
- Volunteers
- 1,084 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine