Clinical trials: Non-suicidal Self-injury (NSSI), open to volunteers
Nonsuicidal Self Injury, Emotion Regulation
Emotion Regulation Dysfunctions in NSSI Adolescents in Naturalistic Contexts
Nonsuicidal self-injury (NSSI) is defined as direct, deliberate bodily harm without suicidal intention. Recent studies indicate that prevalence rates are increasing worldwide, in particular under adolescents, indicating a growing…
- Trial name
- NCT05907421
- Testing
- Acceptance mindset
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Nonsuicidal Self Injury, Risk-Taking
Social Feedback and Dysfunctional Risk Taking in NSSI Adolescents
Nonsuicidal self-injury (NSSI) is defined as direct, intentional physical injury without suicidal intention. Problematic interpersonal relationships and decision-making have been demonstrated to play crucial roles in this…
- Trial name
- NCT05981677
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Non-suicidal Self-injury (NSSI)
Non-Suicidal Self-Injury Digital Psychotherapy Trial
The goal of this randomized, parallel-controlled clinical trial is to investigate multi-dimensional biomarkers (blood, brain imaging, clinical information, and symptom assessment) in adolescents with Non-Suicidal Self-Injury…
- Trial name
- NSSI-DPT (NCT07683234)
- Testing
- digital psychotherapy, Treatment as Usual (TAU)
- Volunteers
- 110 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
NSSI
Effects of Repetitive Transcrannial Magnetic Stimulation on Non-Suicidal Self-Injury
Non-suicidal self-injury (NSSI) refers to a series of direct and consequently repeated injuries to one's body without suicidal intent. At present, it has become an important issue of mental disorders.
- Trial name
- NCT06540300
- Testing
- rTMS stimulation of left M1
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Nanjing Medical University
Non-suicidal Self-injury (NSSI), Adolescent
Neurobiological Markers of Non-suicidal Self-injury and Treatment Mechanisms of Adolescent Self-injury Intervention Skills Training
The goal of this clinical trial is to evaluate the effectiveness and safety of Adolescent Self-Injury Intervention Skills Training (ASIST), a treatment program developed by the research team, compared with treatment as usual…
- Trial name
- ASIST (NCT07910110)
- Testing
- Adolescent Self-Injury Intervention Skills Training (ASIST), Treatment as Usual (TAU)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University
Self-harm Behavior, Eating Disorders
Evaluation of National Highly Specialized Care for Children and Adolescents With Severe Self-Harm or Eating Disorders
National Highly Specialized Care (NHV) is provided in Sweden to children and adolescents with severe and treatment-resistant self-harm or eating disorders when previous treatment has not led to sufficient improvement.
- Conditions
- Self-harm Behavior, Eating Disorders, Non-suicidal Self-injury (NSSI)
- Trial name
- NHV_CHILD (NCT07898059)
- Testing
- National Highly Specialized Care (NHV)
- Where
- 2 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Karolinska Institutet
Self-Harm, Self-Harm, Deliberate
Group Treatment for Self-harming Adolescents and Their Parents: a Randomized Controlled Trial
Adolescent non-suicidal self-injury (NSSI) is common, strongly associated with psychiatric comorbidity and an increased risk of future suicide attempt.
- Conditions
- Self-Harm, Self-Harm, Deliberate, Self-harm Behavior, Non-Suicidal Self Injury
- Trial name
- ERA (NCT07720063)
- Testing
- Emotion Regulation Group Therapy for Self-harming Adolescents, ERA, Functional habits for mental health, FUNK
- Volunteers
- 180 people
- Sponsor
- Karolinska Institutet
Temporal Interference Stimulation, Non Suicidal Self Injury
TIS for NSSI in Adolescent Depression
Temporal Interference Stimulation (TIS) has been successfully used to help patients with depression. However, its role in alleviating self injuries remained uncertain.
- Conditions
- Temporal Interference Stimulation, Non Suicidal Self Injury, Major Depressive Disorder
- Trial name
- NCT07554755
- Testing
- Active Temporal Interference Stimulation (TIS)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Second Hospital of Anhui Medical University
Non-suicidal Self-injury (NSSI)
Acceptance and Commitment Therapy-Based Chatbot for Non-suicidal Self-Injury in Adolescents
The purpose of this study is to evaluate the feasibility and effectiveness of a self-guided digital Acceptance and Commitment Therapy (ACT) intervention for adolescents who engage in non-suicidal self-injury (NSSI).
- Trial name
- NCT07848620
- Testing
- ACT-Based Chatbot
- Volunteers
- 100 people
- Sponsor
- Central China Normal University
Non-suicidal Self-injury (NSSI)
Blended Unified Protocol in Chinese Adolescents With Non-Suicidal Self-Injury
This study utilizes the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Adolescents (UP-A) to address non-suicidal self-injury among Chinese adolescents.
- Trial name
- NCT06858540
- Testing
- Unified protocol for transdiagnostic treatment of emotional disorders in adolescents
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Jian-Jun Ou
Non-Suicidal Self-Injury, Emotional Dysregulation
Integrated Motivational Interviewing and Rational Emotive Behavior Therapy Intervention for Non-Suicidal Self-Injury Among Malaysian Primary School Students: A Feasibility Trial Protocol
This study aims to evaluate the feasibility and preliminary effects of the MIND-SET Intervention Module, an integrated Motivational Interviewing and Rational Emotive Behavior Therapy (MI-REBT) intervention, among Malaysian…
- Trial name
- MIND-SET (NCT07627061)
- Testing
- MIND-SET Intervention Module, PRISMA Mental Health Module
- Where
- Malaysia
- Volunteers
- 105 people
- Sponsor
- Universiti Utara Malaysia
Nonsuicidal Self-Injury, Self-Injurious Behavior
Naltrexone for Nonsuicidal Self-Injury
This randomized, double-blinded, placebo-controlled clinical trial aims to evaluate the efficacy and safety of naltrexone in reducing nonsuicidal self-injurious behavior among individuals with nonsuicidal self-injury.
- Trial name
- NCT07641283
- Testing
- Naltrexone 50mg (Whanin Naltrexone Tab. 50mg)
- Where
- 3 sites in South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Hospital
Non-suicidal Self-injury (NSSI)
Efficacy of Triple-daily 15mA tACS on Adolescent NSSI
This study aims to evaluate the clinical effectiveness of triple-daily 15 mA tACS stimulation in adolescents with Nonsuicidal Self-Injury (NSSI) by comparing the outcomes of active versus sham tACS interventions.
- Trial name
- NCT06919432
- Testing
- Active-tACS (Nexalin Technology, Inc., Houston, TX, USA)
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Shanghai Mental Health Center
Nonsuicidal Self Injury, Prediction Errors
Impact of Emotional Reactivity on Dysfunctional Decision-Making in NSSI Adolescents
Nonsuicidal self-injury (NSSI) is defined as direct, intentional physical injury without suicidal intention. Studies revealed that dysfunctional interpersonal relationships and reward-related decision-making may play crucial…
- Trial name
- NCT05981612
- Where
- China
- Volunteers
- 80 people
- Sponsor
- University of Electronic Science and Technology of China
Non-suicidal Self-injury (NSSI)
Blended Unified Protocol for Chinese Adolescents With Non-Suicidal Self-Injury: A Randomized Controlled Trial
This study is an open-label, randomized controlled trial evaluating the efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Adolescents (UP-A) in reducing non-suicidal self-injury (NSSI) among…
- Trial name
- NCT07110181
- Testing
- a blended version of the Unified Protocol for Adolescents (UP-A), Standard psychiatric treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jian-Jun Ou
Self-harm Behavior, Eating Disorders
Evaluation of National Highly Specialized Care for Adults With Treatment-Resistant Self-Harm and Eating Disorders: Substudy 1
This study aims to evaluate National Highly Specialized Care (NHV) for adults with severe and treatment-resistant self-harm or eating disorders in Sweden.
- Conditions
- Self-harm Behavior, Eating Disorders, Non-suicidal Self-injury (NSSI)
- Trial name
- NHV_ADULTS (NCT07878897)
- Testing
- National Highly Specialized Care (NHV)
- Where
- 2 sites in Sweden
- Volunteers
- 250 people
- Sponsor
- Karolinska Institutet
Transcranial Alternating Current Stimulation, Non-suicidal Self-injury
Intervention Effect of High-Definition Transcranial Alternating Current Stimulation (HD-tACS) on Non-suicidal Self-injury (NSSI)
To investigate the intervention effect of high-definition transcranial alternating current stimulation (HD-tACS) on patients with Non-suicidal Self-injury (NSSI) and its underlying neural mechanism by magnetic resonance imaging…
- Trial name
- NCT06127056
- Testing
- High-Definition Transcranial Alternating Current Stimulation (HD-tACS)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Nonsuicidal Self Injury, Pain Empathy
Altered Neural Pain Empathic Reactivity in NSSI Adolescents
Nonsuicidal self-injury (NSSI) is defined as direct, deliberate bodily harm without suicidal intention. In recent years, growing evidence suggests that NSSI has become a worldwide public health issue.
- Trial name
- NCT05968313
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China