Clinical trials: Non-allergic Rhinitis
Allergic Rhinitis, Non-Allergic Rhinitis
Detection and Use of Nasal Nitrous Oxide and the Electronic Nose
Introduction: Rhinitis, sinonasal polyposis (SP) and asthma are diseases whose pathogenesis is based on inflammation. This will determine the presence of disease, its evolution and its treatment.
- Conditions
- Allergic Rhinitis, Non-Allergic Rhinitis, Nasal Polyps
- Trial name
- EPONA (NCT02476929)
- Testing
- Nasal nitrous oxide, Electronic nose
- Where
- Spain
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Common Cold
Clinical Trial to Optimise Levels of Vitamin D for Rhinovirus Protection
A phase II randomised, placebo-controlled trial to identify the optimal regimen of vitamin D supplementation for rhinovirus protection, determined by host responses to a clinically induced rhinovirus challenge.
- Trial name
- NCT04368520
- Testing
- Vitamin D3
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Common Cold
Efficacy of Homeopathic Nasal Formulation for Management of Experimental Rhinoviral Colds
Common colds affect many people and are the cause of bothersome symptoms such as runny or stuffy nose, sore throat, headache and sneezing.
- Trial name
- NCT00358774
- Testing
- homeopathic nasal spray
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Upper Respiratory Tract Infections
Nasal Spray With Glucose Oxidase Preventing Common Cold in Pre-school Children
To investigate if use of glucosoxidas nasal spray can reduce the number of days with upper respiratory tract infections in children beyond 4 years.
- Trial name
- NCT01883427
- Testing
- Glucose oxidase
- Where
- 4 sites in Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Krister Tano
Effects of; Cold
Role of Cryotherapy in Reduction of Post Operative Endodontic Pain Following Single Visit Root Canal Therapy
AIM : To determine the efficacy of cold saline irrigation in reduction of post operative pain following root canal therapy. METHODOLOGY : Forty patients requiring root canal treatment on permanent single rooted teeth were…
- Trial name
- NCT03044470
- Testing
- cryotherapy
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mamata Dental College
URTI, Common Cold
A Novel Cold and Flu Herbal Blend for Reducing the Duration and Severity of the Common Cold
The aim of this study is to evaluate the efficacy of a Novel Herbal Cold \& Flu Blend in reducing the duration of symptoms of the common cold.
- Trial name
- NOURTI (NCT07642648)
- Testing
- Novel Herbal Cold & Flu Blend
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Common Cold
Efficacy and Safety of Resveratrol and Carbossimetyl Beta Glucan in Treatment of Upper Airways Disease in Infancy
outpatient infants (0-6 months of life), affected by symptoms of upper airways disease will be randomly assigned to two type of intervention: A: treatment group, receiving resveratrol and carbossimetyl beta glucan; B: control…
- Trial name
- VIRNEO (NCT03683108)
- Testing
- Resveratrol and Carbossimetyl Beta Glucan, Saline Solution
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Policlinico Hospital
Common Cold
Duration of ColdZyme® II
The objective of this investigation is to verify that ColdZyme® is deposited onto the throat and estimate the half-life of the ColdZyme® solution in the oropharynx of human volunteers using a log-linear mixed-effects model (LMM).
- Trial name
- NCT03901846
- Testing
- ColdZyme
- Where
- Iceland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Enzymatica AB
Influenza, Common Cold
Pomegranate Products for Prevention of Common Cold
Pomegranate has a long history of use in folk medicine. There is vast data on the health benefits of pomegranate fruit and juice.
- Conditions
- Influenza, Common Cold, Cough, Headache
- Trial name
- NCT00617318
- Testing
- Pomegranate
- Where
- United States
- Volunteers
- 461 people, healthy volunteers welcome
- Sponsor
- Texas Heart Institute
Common Cold/Flu
Study to Investigate the Effects of Hot Drinks on Nasal Airway Resistance and Symptoms of Common Cold
Common cold medicines are often formulated as a hot drink yet there is no evidence in the public domain that presenting the medicine as a hot drink has any impact on symptom severity.
- Trial name
- NCT00495976
- Testing
- A commercially produced cordial drink
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cardiff University
Common Cold
Nasal Swab Study to Explore the Nasal Microbia
The objective of this study is to evaluate the microbial consortia and the host inflammatory factors present in the nasal passages of patients during upper respiratory symptomology and when healthy using culture and molecular…
- Trial name
- NCT02535442
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kimberly-Clark Corporation
Common Cold
Trial to Evaluate the Use of Pomegranate Concentrate (POMx) for the Prevention of Experimental Rhinovirus Infection
Pomegranate has a long history of use in folk medicine. There is vast data on the health benefits of pomegranate fruit and juice.
- Trial name
- NCT00655031
- Testing
- Pomegranate Concentrate (POMx)
- Where
- 3 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- POM Wonderful LLC
Temperature
Core Temperature in Open Water Wetsuited Swimming.
Swimming in cold water is intrinsically unsafe. One of the threats is a fall in core body temperature (Tcore), which adversely affects all body systems and increases the risk of death.
- Trial name
- NCT06685627
- Testing
- Open water wetsuited swimming.
- Where
- Norway
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Common Cold
Evaluation of the Use of Various Assessments of Common Cold Symptoms for Proof of Efficacy of ColdZyme Mouth Spray
This study evaluates the use of various assessments of common cold symptoms for proof of efficacy of ColdZyme Mouth Spray on naturally acquired common colds.
- Trial name
- NCT03831763
- Testing
- ColdZyme
- Where
- 7 sites in Germany
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Enzymatica AB
Common Cold
Experimental Human Rhinovirus Infection
Our primary objective is to set up the Human Rhinovirus (HRV)-model in our centre. In addition, to facilitate future clinical trials, we want to determine optimal read-out parameters and read-out time points for experimental HRV…
- Trial name
- EHRVI (NCT01823640)
- Testing
- Human Rhinovirus strain 16 (HRV-16)
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Healthy
A Study Investigating the Safety and Efficacy of Bio-Active Silver Hydrosol™ in Providing Immune Support
The objective of this study is to investigate the ability of Bio-Active Silver Hydrosol™ in providing immune support in healthy adult males and females participating in intense aerobic exercise.
- Trial name
- NCT04144673
- Testing
- Silver Hydrosol
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Natural Immunogenics Corp.
COVID-19 Respiratory Infection, FLU
Effect of Kunamin in SARS-CoV-2 RT-PCR Positive Covid-19 Patients
The primary objective of this study is to determine the safety and efficacy profile of the food supplement (KUNAMIN®) containing grape juice, seed, stem, and bark given to patients treated with the established treatment regimen…
- Conditions
- COVID-19 Respiratory Infection, FLU, Cold; Influenza, Bacterial Pneumonia
- Trial name
- NCT05417997
- Testing
- Kunamin®, Favipiravir, Enoxaparin
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- RAAS Nutritionals, LLC
Common Cold
A Trial of Echinacea in Children
This is a randomized trial to determine if echinacea is effective in shortening the length and/or lessening the severity of colds in children 2 through 11 years old.
- Trial name
- NCT00029211
- Testing
- Echinacea
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Acute Nasopharyngitis
Safety and Pharmacokinetic Study of Intranasal 2-DG in Healthy Volunteers
2-DG-01 is a randomized, double-blind, placebo-controlled, single and multiple ascending dose phase 1 study assessing safety, tolerability and pharmacokinetics of 2-DG in normal healthy volunteers (NHV).
- Trial name
- NCT05314933
- Testing
- 2-Deoxyglucose
- Where
- Austria
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- G.ST Antivirals GmbH
Common Cold, Healthy
Efficacy Study of A Lotion to Prevent Common Colds
The purpose of this of this study is to determine if 3804-250A can prevent the common cold caused by the rhinovirus when applied to the hands.
- Trial name
- NCT00993759
- Testing
- 3804-250A
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- The Dial Corporation