Clinical trials: Non-Suicidal Self-Injury
Self-Harm, Depression
Signatures of N-Ac for Non-Suicidal Self-Injury in Adolescents
To measure NAC-induced changes to concentrations of glutathione (GSH) in the anterior cingulate cortex (ACC) as measured by magnetic resonance spectroscopy (MRS) in 36 adolescents and young adults with NSSI (12 in each group…
- Conditions
- Self-Harm, Depression, Suicide
- Trial name
- NCT04005053
- Testing
- N-acetyl cysteine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Minnesota
Nonsuicidal Self Injury, Self Hatred
Single-Session Intervention Targeting Self-Injurious Behavior in Adolescents
Participants (aged 13-16) will be randomized to: (1) an online, active control group program encouraging feelings disclosure (i.e.
- Conditions
- Nonsuicidal Self Injury, Self Hatred, Suicidal Thoughts, Suicide Attempts
- Trial name
- Project SAVE (NCT04498143)
- Testing
- Project SAVE ("Stop Adolescent Violence Everywhere") SSI, Active Comparator: Supportive Therapy ("Share Your Feelings") SSI
- Where
- United States
- Volunteers
- 565 people, healthy volunteers welcome
- Sponsor
- University of Denver
Depression, Self-injurious Behavior
Interpersonal Psychotherapy for Depressed Adolescents Engaging in Non-suicidal Self-injury
The purpose of this study is to examine the feasibility of using Interpersonal Psychotherapy for Depressed Adolescents (IPT-A) to treat adolescents who are experiencing symptoms of depression and are engaging in non-suicidal…
- Trial name
- IPT-ASI (NCT00401102)
- Testing
- Interpersonal Psychotherapy for Depressed Adolescents
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New York State Psychiatric Institute
Self-Injurious Behavior, Self Harm
Treating Self Injurious Behavior: A Novel Brain Stimulation Approach
The purpose of this study is to explore the tolerability and effectiveness of transcranial direct current stimulation (tDCS) as a potential treatment for non-suicidal self-injury (NSSI).
- Conditions
- Self-Injurious Behavior, Self Harm, Self-injury, Self-inflicted Injury
- Trial name
- NCT04244786
- Testing
- Transcranial direct current stimulation, No intervention
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- New York State Psychiatric Institute
Lesch-Nyhan Disease, Self-injurious Behavior
Ecopipam Treatment of Self-Injurious Behavior in Subjects With Lesch-Nyhan Disease
The purpose of this research study is to gather scientific information about the effectiveness and safety of the study drug, Ecopipam (PSYRX 101), for the treatment of self-injurious behaviors when compared with the effectiveness…
- Trial name
- NCT01751802
- Testing
- Ecopipam
- Where
- 2 sites in United States, Spain
- Volunteers
- 9 people
- Sponsor
- Emalex Biosciences Inc.
Tuberous Sclerosis Complex, Self-injury
Rapalogues for Autism Phenotype in TSC: A Feasibility Study
The purpose of this study is to assess the feasibility and safety of administering rapalogues, sirolimus or everolimus, in participants with Tuberous Sclerosis Complex (TSC) and self-injury and to measure cognitive and behavioral…
- Conditions
- Tuberous Sclerosis Complex, Self-injury, Autism
- Trial name
- RAPT (NCT01929642)
- Testing
- Sirolimus, Everolimus
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Suicidal Ideation
Observational Study to Compare Outcomes of Different Psychiatric Treatment of Suicidal Adolescents
To address the unmet need of optimizing the treatment and management for adolescent suicidality, the investigators propose to evaluate the effectiveness and safety of telehealth services compared to inpatient and OCIC for…
- Trial name
- Pre-START (NCT04625686)
- Testing
- Mental Health Treatment
- Where
- 4 sites in United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Depression
iTBS for Adolescent Depression: An Open Label Study Evaluating Safety and Efficacy of Treatment
This is an open label, pilot, feasibility study evaluating effects of Intermittent Theta Burst Transcranial Magnetic Stimulation (iTBS) on 5 eligible adolescents for the treatment of depression.
- Trial name
- NCT04485455
- Testing
- iTBS Device/Motor Threshold Coil, iTBS Device/Treatment Coil
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of North Carolina, Chapel Hill
Depression, Anxiety
Digital Mental Health Service for Non-Treatment Seeking Young Adults
This is a feasibility trial of a personalized 8-week text messaging intervention aimed at young adults (ages 18-25) with depression and anxiety who are not interested in -- or experience barriers to -- receiving traditional…
- Conditions
- Depression, Anxiety, Suicidal Ideation
- Trial name
- NCT04948268
- Testing
- Adaptive messaging intervention, Non-personalized messaging intervention, Coaching
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Northwestern University
Problem Behavior, Self-injury
Resurgence as Choice: Basic and Clinical Studies
Background: Functional communication training (FCT) is a commonly used intervention for teaching appropriate communication skills to children with intellectual disabilities who exhibit severe destructive behavior.
- Conditions
- Problem Behavior, Self-injury, Communication
- Trial name
- NCT03423940
- Testing
- Functional communication training
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Suicidal Ideation, Suicide, Attempted
Safety Planning in Juvenile Justice for Suicidal Youth
This study will examine the feasibility and acceptability of a program designed to conduct safety planning with youth in the juvenile justice system who are at risk for a suicide attempt and/or self-injury and to increase the…
- Conditions
- Suicidal Ideation, Suicide, Attempted, Nonsuicidal Self-injury
- Trial name
- Safety (NCT03655470)
- Testing
- Safety Planning, Standard care
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Brown University
Self-Injurious Behavior, Deliberate Self-Harm
A Study Examining Adolescents With Non-Suicidal Self-Injury
This study will examine longitudinal brain development in young adolescent girls with a history of Non-Suicidal Self-Injury (NSSI).
- Trial name
- RDoC (NCT02947308)
- Where
- 3 sites in United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Borderline Personality Disorder, Suicide
Comparing Treatments for Self-Injury and Suicidal Behavior in People With Borderline Personality Disorder
This study will compare the effectiveness of two treatments, dialectical behavior therapy versus fluoxetine with clinical management, for reducing the risk of self-injury and suicidal behavior in people with borderline…
- Trial name
- NCT00834834
- Testing
- Fluoxetine, DBT, Citalopram
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- New York State Psychiatric Institute