Clinical trials: Nocturnal Enuresis
Overactive Bladder, Children
Gene Expression in the Overactive Bladder in Children
The aim of this study (the hypothesis) is to identify differences in the gene expression profile in the bladder muscle and hereby gain greater knowledge about the muscular mechanisms that cause overactive bladder and daytime…
- Trial name
- NCT02086058
- Where
- Denmark
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Enuresis, Nocturnal
Comparative Study of the Efficacy of TENS Versus Placebo in Isolated Primary Enuresis
Nocturnal enuresis is a functional urinary disorder in children. It is intermittent urinary incontinence during sleep in children aged 5 years and older.
- Trial name
- TENS-Enuresis (NCT04413461)
- Testing
- TENS
- Where
- 4 sites in France
- Volunteers
- 54 people
- Sponsor
- Fondation Lenval
Nocturnal Enuresis, Polysomnography
Sleep and Nocturnal Enuresis: Ambulatory Polysomnographic Study
Full ambulatory polysomnography at home performed two nights in 30 healthy children and one night in 30 children with mono-symptomatic nocturnal enuresis (15 with polyuria and 15 without polyuria).
- Trial name
- NCT03477812
- Testing
- Polysomnography (Full sleep registration)
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Enuresis, Obstructive Sleep Apnea
Intranasal Steroids for the Treatment of Nocturnal Enuresis With Associated Obstructive Sleep Apnea
Enuresis (E) or bedwetting is a common pediatric complaint, and recent research has discovered a link with obstructive sleep apnea (OSA).
- Conditions
- Enuresis, Obstructive Sleep Apnea, Sleep Disordered Breathing
- Trial name
- NCT01861145
- Testing
- Bed Alarm, Nasonex
- Where
- 2 sites in Canada
- Sponsor
- University of Alberta
Enuresis, Polyuria
Influence of Food-intake on Desmopressin Oral Tablets and MELT-formulation
Alarm-treatment as well as Desmopressin, a synthetic analogue of human vasopressin, are considered the only evidence-based medicine (EBM) IA treatments in monosymptomatic nocturnal enuresis (MNE).
- Trial name
- TM (NCT01036841)
- Testing
- desmopressin tablet, desmopressin MELT formulation
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- University Hospital, Ghent
Uterine Prolapse, Urine Incontinence
The Assessment of Fibrin Clot Phenotype and Thrombin Generation in Women After Urogynecological Surgeries.
Determination of fibrin clot properties along with thrombin generation in women after urigynecological surgery.
- Trial name
- NCT07295782
- Testing
- determination of fibrin clot properties
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Nocturnal Enuresis in Children, Primary Nocturnal Enuresis
Potential Adjuvant Therapies for Children With Primary Nocturnal Enuresis
To examine the possible reduction in dietary salt intake on the outcomes of nocturnal enuresis
- Trial name
- NCT07876947
- Testing
- Dietary Salt Restriction, Omega Supplementation
- Volunteers
- 100 people
- Sponsor
- Cairo University
Depression, Depressive State
A Study to Compare the Pharmacokinetic Profiles of Etravil® Tablet 10mg and Etravil® Tablet 25mg
To evaluate the pharmacokinetics of single oral dose of Amitriptyline hydrochloride film-coated tablet 10mg \& 25mg
- Conditions
- Depression, Depressive State, Enuresis
- Trial name
- DWETR (NCT01367080)
- Testing
- DWETR10, DWETR25
- Where
- South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Dong Wha Pharmaceutical Co. Ltd.
Nocturnal Enuresis
Urotherapy vs. Urotherapy With Constipation Treatment for Nocturnal Enuresis
Constipation treatment has been found to ameliorate symptoms in some patients with nocturnal enuresis (bed wetting at night). This study aims to explore if treatment of patients without overt constipation (As defined by the ROME…
- Trial name
- NCT02337413
- Testing
- Polyethylene glycol 3350, Constipation behavioral therapy, Urotherapy
- Where
- Israel
- Sponsor
- Rabin Medical Center
Urinary Incontinence, Menopause
Effects of Tanzberger Versus Pelvic Floor Muscle Exercises on Urinary Incontinence
Randomized clinical trial (RCT) will be conducted to compare the effects of Tanzberger exercises and pelvic floor muscle training on urinary incontinence and quality of life in post_menopausal females suffering from urine…
- Trial name
- NCT05916820
- Testing
- Tanzberger Exercises, Pelvic floor muscle training
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Lower Urinary Tract Disorder, Enuresis Nocturnal
Bladder Wall Thickness for Treatment Response in Children With Lower Urinary Tract Dysfunction or Enuresis
This study aims to evaluate the association between bladder wall thicknes and treatment response in children presenting with enuresis or lower urinary tract dysfunction.
- Conditions
- Lower Urinary Tract Disorder, Enuresis Nocturnal, Bladder Wall Thickness
- Trial name
- NCT07656935
- Testing
- Bladder Wall Thickness Measurement by Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Enuresis, Nocturnal
Enuresis Alarm - Is a Manual Trigger System Beneficial?
The purpose of this study is to evaluate whether the bedwetting alarm trigger activated by parents to wake their child, in addition to the moisture alarm, will improve treatment success compared to the moisture alarm alone.
- Trial name
- NCT03522818
- Testing
- Manual Trigger, Normal
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Gina Lockwood
Daytime Urinary Incontinence
Micturition Reeducation in Children With Cerebral Palsy
This study evaluates the effectiveness of a voiding reeducation program as treatment for incontinence in children with a brain injury.
- Trial name
- NCT02364063
- Testing
- urotherapy with or without pharmacotherapy
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Ghent
Enuresis
Family Help Program: Nighttime Enuresis Treatment Program
The purpose of the Strongest Families (formerly Family Help Program)is to evaluate the effectiveness of the Strongest Families distance intervention compared to usual or standard care that is typically provided to children with…
- Trial name
- NCT00270621
- Testing
- FHP Night time ENuresis Intervention
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Oncology, Incontinence
Mebeverine For 1st Year Daytime And Nocturnal Incontinence After Orthotopic W-Ileal Neobladders
A randomized controlled trial to assess clinically the efficacy of the selective ileum spasmolytic mebeverine on daytime incontinence and nocturnal enuresis of orthotopic w-ileal neobladders and quality of life effect within 1…
- Conditions
- Oncology, Incontinence, Incontinence, Daytime Urinary, Incontinence, Nighttime Urinary
- Trial name
- NCT03147599
- Testing
- Coloverin
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Enuresis
Efficacy and Safety of Vitamin D Supplementation Combined With Alarm Therapy in Treating Nocturnal Enuresis
This prospective, randomized, two-arm, parallel-design controlled clinical trial aims to determine whether high-dose vitamin D supplementation combined with alarm therapy improves outcomes in children with primary monosymptomatic…
- Trial name
- NCT06508333
- Testing
- alarm therapy, Vitamin D3
- Where
- China
- Volunteers
- 262 people
- Sponsor
- Xing Liu
Enuresis, Nocturnal
Uroflowmetry and Nocturnal Enuresis
This study will evaluate the uroflowmetry parameters of patients which were treated for enuresis.
- Trial name
- NCT07028645
- Testing
- desmopressin melt form 120 μg, Desmopressin lyophilisate (Melt), Propiverine tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Furkan Adem Canbaz
Urinary Bladder, Overactive, Incontinence, Urge
Post-procedural Pain Associated With 5 Versus 20 Intravesical Injections of Onabotulinumtoxin A
Currently, in clinical practice there has been no standardization in the number of injections a single dose of intradetrusor onabotulinumtoxin A is administered in.
- Conditions
- Urinary Bladder, Overactive, Incontinence, Urge, Incontinence, Urinary, Urinary Urge Incontinence
- Trial name
- NCT04305743
- Testing
- OnabotulinumtoxinA 100 UNT
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of South Florida
Monosymptomatic Nocturnal Enuresis
Desmopressin Melt: Impact on Sleep and Daytime Functioning
Nocturnal enuresis affects 10% of the 7-year-old children and is essentially caused by a mismatch between nocturnal bladder capacity and the amount of urine produced during the night together with failure of the child to awaken…
- Trial name
- SLEEP (NCT01645475)
- Testing
- Desmopressin lyophilisate (Melt)
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent
Sleep Fragmentation, Poor Quality Sleep
Impact of Behavioral Treatment of Insomnia on Nighttime Urine Production
Nocturia is prevalent in older adults and it vastly reduces quality of life. Yet its treatment remains inadequate because its causes are not well understood, especially nocturnal polyuria or increased urine production at night.
- Conditions
- Sleep Fragmentation, Poor Quality Sleep, Nocturia, Nocturnal Enuresis
- Trial name
- NCT03883724
- Testing
- Brief behavioral treatment of insomnia (BBTI), Information-only control (IC)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh