Clinical trials: Neuropathy
Chemotherapy-induced Neuropathy
Home-Based Exercise and Vagus Nerve Stimulation for Chemotherapy-Induced Neuropathy
Background: Studies highlight the potential benefits of home-based exercise for cancer survivors with chemotherapy-induced neuropathy (CIN); however, its effectiveness in alleviating CIN-related sensorimotor impairments and…
- Trial name
- CIN (NCT07877558)
- Testing
- Active non-invasive vagus nerve stimulation (nVNS), Home-based aerobic and resistance exercise program
- Where
- 3 sites in Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Anti-MAG Neuropathy
First in Human Study to Test the Safety and Preliminary Efficacy of PPSGG in Patients With Anti-MAG Neuropathy
In this study, the new drug called PPSGG (PN-1007) will be tested. Preliminary studies conducted in animals suggest PPSGG (PN-1007) might be a good treatment for reducing levels of anti-MAG antibodies in patients with anti-MAG…
- Trial name
- NCT04568174
- Testing
- PPSGG
- Where
- 7 sites in France, Netherlands and 3 more
- Volunteers
- 1 people
- Sponsor
- Polyneuron Pharmaceuticals AG
Diabetic Neuropathy, Arthritis
Effect of Holofiber Socks and Bedding on Pain and Quality of Sleep in Subjects With Chronic Foot Pain
This study is designed to assess the effects of socks and bedding materials on foot pain, the level of blood oxygen existing in the feet and quality of sleep in subjects who have chronic foot pain from either diabetic neuropathy…
- Conditions
- Diabetic Neuropathy, Arthritis, Peripheral Arterial Disease, Plantar Fasciitis
- Trial name
- NCT00458497
- Testing
- Holofiber fabric, PET fabric
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Southern California Institute for Research and Education
Amyloidosis Cardiac, Carpal Tunnel Syndrome
Prevalence of Wild Type Transthyretin Cardiac Amyloidosis in Patients Operated for Idiopathic Carpal Tunnel Syndrome
Wild-type transthyretin cardiac amyloidosis is an underdiagnosed depository disease in which fibril monomers of misfolded amyloid protein accumulates in various tissues, including the heart, and cause tissue dysfunction.
- Trial name
- CACTuS (NCT03996382)
- Testing
- DPD Scintigraphy
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Aarhus University Hospital Skejby
Painful Diabetic Neuropathy
Electromagnetic Stimulation (FREMS) in Patients With Painful Diabetic Neuropathy
We postulate that frequency-modulated electromagnetic stimulation (FREMS) may decrease pain in patients with painful diabetic neuropathy.
- Trial name
- NCT00337324
- Testing
- Frequency-modulated electromagnetic neural stimulation
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- IRCCS San Raffaele
Painful Diabetic Neuropathy
Trazodone in Painful Diabetic Neuropathy
The aim of the study is to collect preliminary information on the effect of low doses of trazodone on pain intensity in patients with painful diabetic neuropathy and to evaluate the neuropathic pain symptoms, anxiety, sleep…
- Trial name
- NCT03202979
- Testing
- Trazodone 20 mg, Trazodone 10 mg
- Where
- 20 sites in Czechia, Hungary and 1 more
- Volunteers
- 142 people
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Diabetic Neuropathies
Effect of Neurodynamic Mobilization Techniques in Patients With Diabetic Neuropathy
Neurodynamic mobilization Techniques and Selected Physical program used as a treatment for diabetic neuropathy patients and assessed by nerve condition study and function outcome.
- Trial name
- NCT05628168
- Testing
- Neurodynamic Mobilization Techniques, Selected Physical Therapy Program
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- October 6 University
Laser Acupuncture, Flexor Tendon Repair
Efficacy of Laser Acupuncture on Carpal Tunnel Syndrome Following Hand Flexor Tendon Repair
The purpose of this study is to determine the efficacy of laser acupuncture in alleviating CTS symptoms following flexor tendon repair in the hand.
- Conditions
- Laser Acupuncture, Flexor Tendon Repair, Hand Surgery, Carpal Tunnel Syndrome (CTS)
- Trial name
- LASER (NCT07014774)
- Testing
- Laser acupuncture, Traditional Therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Peripheral Nervous System Diseases, Testicular Neoplasms
Establishing of Neuronal-like Cells From Patients With Cisplatin-Induced Peripheral Neuropathy
This study targets patients with cisplatin-induced peripheral neuropathy and will allow us to: a) study peripheral neuropathy in diverse human sensory neurons in ways that were not possible previously; b) gain insight on…
- Trial name
- NCT02492360
- Testing
- Blood sample collection, Report of peripheral neuropathy after cisplatin therapy
- Where
- United States
- Sponsor
- Costantine Albany
Diabetic Foot Ulcer, Deep Diabetic Foot Ulcer
Comparative Effectiveness of Two Acellular Matrices (Dermacell vs. Integra) for Management of Deep Diabetic Foot Ulcers
Diabetes-related foot ulcers (DFUs) are a leading cause of hospitalization and amputation worldwide, and account for 33% of all direct costs of diabetes care in the US.
- Trial name
- NCT03476876
- Testing
- Dermacell, Integra
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Baylor College of Medicine
Ultrasound, Education
Tele-Ultrasound: VIrtual Hands-on Education for Novice Users
This study is intended to perform a comparative analysis of novice ultrasound users when taught in person versus virtually. This study aims to show that students will not demonstrate a statistical difference in scores learning in…
- Conditions
- Ultrasound, Education, Virtual
- Trial name
- NCT05013476
- Testing
- Butterfly handheld ultrasound machine
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Small-Fiber Neuropathy
Evaluation of Pregabalin in Idiopathic Small Fiber Neuropathy
Idiopathic Small Fiber Neuropathy (called SFN for short), is a condition where nerves that sense pain have become damaged, and often painful.
- Trial name
- NCT00787462
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Diabetes Mellitus, Foot Ulcers
Ulcer Monitoring in Diabetes Mellitus
Telemedicine technology enables a direct and online text- and image communication in the treatment system from patient to the ulcer specialist.
- Trial name
- Telesaar (NCT01608425)
- Testing
- telemedicine consultations
- Where
- 6 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Johnny Froekjaer
Sciatica, Electroacupuncture
Effectiveness of Electro-acupuncture and Manual Therapy on Pain and Fucntion in Patients With Sciatica
The aims of the study are: To study the pain efficacy of an electroacupuncture and manual therapy protocol versus the use of manual therapy in patients with sciatica.
- Conditions
- Sciatica, Electroacupuncture, Manual Therapy
- Trial name
- NCT04764890
- Testing
- Electroacupuncture, Manual therapy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- CEU San Pablo University
Diabetic Foot Ulcer
Evaluating the Efficacy NeoThelium FT in the Treatment of Diabetic Foot Ulcers
This is a randomized controlled crossover trial evaluating the efficacy of NeoThelium FT in conjunction with standard of care vs. standard of care alone in treating diabetic foot ulcers.
- Trial name
- NCT06938685
- Testing
- Standard of Care, NeoThelium FT
- Where
- 8 sites in United States
- Volunteers
- 132 people
- Sponsor
- NuScience Medical Biologics, LLC
HFpEF - Heart Failure With Preserved Ejection Fraction, HFmrEF
US Benchmarking Clinical Study
The goal of this observational study is to measure shear wave velocity (SWV) in patients with non-reduced left ventricular ejection fraction (LVEF) heart failure and left ventricular hypertrophy, with or without transthyretin…
- Conditions
- HFpEF - Heart Failure With Preserved Ejection Fraction, HFmrEF, ATTR-CM (Transthyretin Amyloid Cardiomyopathy), Left Ventricular Hypertrophy
- Trial name
- EMS-CT-1 (NCT07215715)
- Where
- 3 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- eMyosound SAS
Sciatica Acute, Sciatica
COMPARISON OF EFFICACY OF DIFFERENT DRUG COMBINATIONS IN ACUTE SCIATICA
The goal of this clinical trial is to compare different combinations of diclofenac with diclofenac monotherapy in acute sciatica.
- Trial name
- EDCLAS (NCT05626140)
- Testing
- Lacosamide 50 MG Oral Tablet [Vimpat], Codeine Phosphate, Diclofenac Sodium
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Pakistan Institute of Medical Sciences
Diabetic Foot Ulcer
Pathogenicity Factors of Staphylococcus Pettenkoferi in Foot Wounds and Osteitis in Diabetic Patients
Gram-positive cocci, particularly Staphylococcus aureus and coagulase-negative staphylococci (SCoN), are the bacteria most frequently isolated from diabetic foot ulcers. Although studies have been carried out on the role of S.
- Trial name
- PETTENK-OS (NCT06688084)
- Testing
- Molecular epidemiology of the collection, Study of the resistome of the S. pettenkoferi population, Study of the virulome of the S. pettenkoferi population
- Where
- France
- Volunteers
- 230 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Carpal Tunnel Syndrome, Trigger Finger
Question Prompt List for Common Hand Conditions
Patients with common hand conditions will be randomized to one of two groups- one will receive a question prompt list, the other will receive a list of 3 questions
- Conditions
- Carpal Tunnel Syndrome, Trigger Finger, Trigger Thumb, Dupuytren Contracture
- Trial name
- NCT03868449
- Testing
- Question Prompt List, 3 questions
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Stanford University
Diabetic Neuropathy, Painful
Tolerability of Switching to Duloxetine for the Management of Diabetic Nerve Pain
This study is to compare the tolerability of different methods for switching from another medication to duloxetine for the management of diabetic nerve pain.
- Trial name
- NCT00266643
- Testing
- duloxetine hydrochloride
- Where
- 20 sites in United States, Puerto Rico
- Volunteers
- 205 people
- Sponsor
- Eli Lilly and Company